Valentino Cattori

Summary

Affiliation: University of Zurich
Country: Switzerland

Publications

  1. doi request reprint The kinetics of feline leukaemia virus shedding in experimentally infected cats are associated with infection outcome
    Valentino Cattori
    Clinical Laboratory, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland
    Vet Microbiol 133:292-6. 2009
  2. doi request reprint Inhibition of Feline leukemia virus replication by the integrase inhibitor Raltegravir
    Valentino Cattori
    Clinical Laboratory, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 260, CH 8057 Zurich, Switzerland
    Vet Microbiol 152:165-8. 2011
  3. doi request reprint Association between endogenous feline leukemia virus loads and exogenous feline leukemia virus infection in domestic cats
    Ravi Tandon
    Clinical Laboratory, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 260, 8057 Zurich, Switzerland
    Virus Res 135:136-43. 2008
  4. ncbi request reprint Cellular segregation of feline leukemia provirus and viral RNA in leukocyte subsets of long-term experimentally infected cats
    Andrea C Pepin
    Clinical Laboratory, Vetsuisse Faculty, University of Zurich, Switzerland
    Virus Res 127:9-16. 2007
  5. ncbi request reprint Vaccination against the feline leukaemia virus: outcome and response categories and long-term follow-up
    Regina Hofmann-Lehmann
    Clinical Laboratory, Vetsuisse Faculty, University of Zurich, Winterthurerstr 260, CH 8057 Zurich, Switzerland
    Vaccine 25:5531-9. 2007
  6. doi request reprint Real-time PCR investigation of feline leukemia virus proviral and viral RNA loads in leukocyte subsets
    Valentino Cattori
    Clinical Laboratory, Vetsuisse Faculty, University of Zurich, Winterthurerstreet 260, CH 8057 Zurich, Switzerland
    Vet Immunol Immunopathol 123:124-8. 2008
  7. ncbi request reprint Real-time PCR-based prevalence study, infection follow-up and molecular characterization of canine hemotropic mycoplasmas
    Nicole Wengi
    Department for Farm Animals, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 260, 8057 Zurich, Switzerland
    Vet Microbiol 126:132-41. 2008
  8. pmc Phylogenetic analysis of "Candidatus Mycoplasma turicensis" isolates from pet cats in the United Kingdom, Australia, and South Africa, with analysis of risk factors for infection
    Barbara Willi
    Clinical Laboratory, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 260, 8057 Zurich, Switzerland, and Bryanston Veterinary Hospital, South Africa
    J Clin Microbiol 44:4430-5. 2006
  9. pmc Dominance of highly divergent feline leukemia virus A progeny variants in a cat with recurrent viremia and fatal lymphoma
    A Katrin Helfer-Hungerbuehler
    Clinical Laboratory, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland
    Retrovirology 7:14. 2010
  10. pmc Exposure of cats to low doses of FeLV: seroconversion as the sole parameter of infection
    Andrea Major
    Clinical Laboratory, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 260, 8057, Zurich, Switzerland
    Vet Res 41:17. 2010

Detail Information

Publications34

  1. doi request reprint The kinetics of feline leukaemia virus shedding in experimentally infected cats are associated with infection outcome
    Valentino Cattori
    Clinical Laboratory, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland
    Vet Microbiol 133:292-6. 2009
    ..To determine the clinically relevant outcome of FeLV infection in exposed cats, however, p27 antigen levels in the peripheral blood should be measured...
  2. doi request reprint Inhibition of Feline leukemia virus replication by the integrase inhibitor Raltegravir
    Valentino Cattori
    Clinical Laboratory, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 260, CH 8057 Zurich, Switzerland
    Vet Microbiol 152:165-8. 2011
    ..Therefore, Raltegravir may be a potential therapeutical agent for felids with progressive FeLV infection...
  3. doi request reprint Association between endogenous feline leukemia virus loads and exogenous feline leukemia virus infection in domestic cats
    Ravi Tandon
    Clinical Laboratory, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 260, 8057 Zurich, Switzerland
    Virus Res 135:136-43. 2008
    ..In conclusion, our results demonstrated an association between enFeLV loads and FeLV replication but not outcome of infection. enFeLV should be considered as an important confounder in experimental FeLV infection or vaccination studies...
  4. ncbi request reprint Cellular segregation of feline leukemia provirus and viral RNA in leukocyte subsets of long-term experimentally infected cats
    Andrea C Pepin
    Clinical Laboratory, Vetsuisse Faculty, University of Zurich, Switzerland
    Virus Res 127:9-16. 2007
    ..The herein described methods are important prerequisites to gain a deeper insight into the pathogenesis of FeLV infection...
  5. ncbi request reprint Vaccination against the feline leukaemia virus: outcome and response categories and long-term follow-up
    Regina Hofmann-Lehmann
    Clinical Laboratory, Vetsuisse Faculty, University of Zurich, Winterthurerstr 260, CH 8057 Zurich, Switzerland
    Vaccine 25:5531-9. 2007
    ..Persistence of plasma viral RNA was moderately associated with reactivation of FeLV infection. In conclusion, sensitive molecular assays are important tools for reviewing pathogenesis of FeLV infection...
  6. doi request reprint Real-time PCR investigation of feline leukemia virus proviral and viral RNA loads in leukocyte subsets
    Valentino Cattori
    Clinical Laboratory, Vetsuisse Faculty, University of Zurich, Winterthurerstreet 260, CH 8057 Zurich, Switzerland
    Vet Immunol Immunopathol 123:124-8. 2008
    ..These results indicate that FeLV persistent viremia is associated with secondary viremia of bone marrow origin, whereas regressive cats only sustain a non-productive infection in low numbers of lymphocytes...
  7. ncbi request reprint Real-time PCR-based prevalence study, infection follow-up and molecular characterization of canine hemotropic mycoplasmas
    Nicole Wengi
    Department for Farm Animals, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 260, 8057 Zurich, Switzerland
    Vet Microbiol 126:132-41. 2008
    ..sanguineus. Nonetheless, veterinarians may expect hemoplasma infections in dogs with a travel history and/or after potential tick vector exposure...
  8. pmc Phylogenetic analysis of "Candidatus Mycoplasma turicensis" isolates from pet cats in the United Kingdom, Australia, and South Africa, with analysis of risk factors for infection
    Barbara Willi
    Clinical Laboratory, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 260, 8057 Zurich, Switzerland, and Bryanston Veterinary Hospital, South Africa
    J Clin Microbiol 44:4430-5. 2006
    ..In summary, "Candidatus Mycoplasma turicensis" infection in pet cats exists over a wide geographical area and significantly decreased PCV values are observed in cats coinfected with other feline hemoplasmas...
  9. pmc Dominance of highly divergent feline leukemia virus A progeny variants in a cat with recurrent viremia and fatal lymphoma
    A Katrin Helfer-Hungerbuehler
    Clinical Laboratory, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland
    Retrovirology 7:14. 2010
    ..5 years after the initial experimental exposure to FeLV-A/Glasgow-1. The goals of the present study were to investigate this FeLV reoccurrence and molecularly characterize the progeny viruses...
  10. pmc Exposure of cats to low doses of FeLV: seroconversion as the sole parameter of infection
    Andrea Major
    Clinical Laboratory, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 260, 8057, Zurich, Switzerland
    Vet Res 41:17. 2010
    ..Therefore, commonly used detection methods do not detect all FeLV-infected animals, possibly leading to an underestimation of the prevalence of infection...
  11. ncbi request reprint Copy number polymorphism of endogenous feline leukemia virus-like sequences
    Ravi Tandon
    Clinical Laboratory, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 260, CH 8057 Zurich, Switzerland
    Mol Cell Probes 21:257-66. 2007
    ..The assays described herein are important prerequisites to quantify enFeLV loads and thus to investigate the influence of enFeLV loads on the course of FeLV infection...
  12. doi request reprint Absolute quantitation of feline leukemia virus proviral DNA and viral RNA loads by TaqMan real-time PCR and RT-PCR
    Valentino Cattori
    Clinical Laboratory, University of Zeurich, Winterthurerstrasse, Zurick, Switzerland
    Methods Mol Biol 429:73-87. 2008
    ..cRNA is synthesized from the linearized plasmid DNA. Standard DNA and RNA are quantified, diluted and used to determine efficiency, sensitivity, linear amplification range, and precision of the quantitative TaqMan real-time PCR assays...
  13. doi request reprint How molecular methods change our views of FeLV infection and vaccination
    Regina Hofmann-Lehmann
    Clinical Laboratory, Vetsuisse Faculty, University of Zurich, Winterthurerstr 260, CH 8057 Zurich, Switzerland
    Vet Immunol Immunopathol 123:119-23. 2008
    ..The use of sensitive molecular methods will contribute to a more in-depth understanding of the FeLV pathogenesis...
  14. pmc Prevalence, risk factor analysis, and follow-up of infections caused by three feline hemoplasma species in cats in Switzerland
    Barbara Willi
    Clinical Laboratory, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 260, 8057 Zurich, Switzerland
    J Clin Microbiol 44:961-9. 2006
    ....
  15. pmc Real-time PCR investigation of potential vectors, reservoirs, and shedding patterns of feline hemotropic mycoplasmas
    Barbara Willi
    Clinical Laboratory, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 260, 8057 Zurich, Switzerland
    Appl Environ Microbiol 73:3798-802. 2007
    ..Neither the investigated tick nor the rodent population seems to represent a major reservoir for feline hemotropic mycoplasmas in Switzerland...
  16. doi request reprint Quantification of endogenous and exogenous feline leukemia virus sequences by real-time PCR assays
    Ravi Tandon
    Clinical Laboratory, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 260, 8057 Zurich, Switzerland
    Vet Immunol Immunopathol 123:129-33. 2008
    ..In conclusion, the quantitative real-time PCR assays described herein are important prerequisites to quantify enFeLV proviral loads in felids and thus are important tools to investigate the role of enFeLV loads in FeLV infection...
  17. pmc Stimulation with a class A CpG oligonucleotide enhances resistance to infection with feline viruses from five different families
    Céline Robert-Tissot
    Clinical Laboratory, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 260, CH 8057, Zurich, Switzerland
    Vet Res 43:60. 2012
    ..Altogether, our data highlight the promising potential of CpG-A to induce a preventive antiviral state in the cat and to protect feline populations against a broad range of virus infections...
  18. doi request reprint Quantification of the humoral immune response and hemoplasma blood and tissue loads in cats coinfected with 'Candidatus Mycoplasma haemominutum' and feline leukemia virus
    Godelind A Wolf-Jäckel
    Clinical Laboratory, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland
    Microb Pathog 53:74-80. 2012
    ..The tissue loads appeared to correlate with the duration of infection and with the blood loads, but no evidence of significant CMhm tissue sequestration was found...
  19. pmc Molecular Investigations of Rickettsia helvetica infection in dogs, foxes, humans, and Ixodes ticks
    Felicitas S Boretti
    Clinic for Small Animal Internal Medicine, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 260, 8057 Zurich, Switzerland
    Appl Environ Microbiol 75:3230-7. 2009
    ..e., R. helvetica was 13 times more frequent in unfed ticks than the tick-borne encephalitis virus), many mammals may be exposed to R. helvetica. The PCR assay described here represents an important tool for studying this topic...
  20. doi request reprint Feline leukemia virus infection: a threat for the survival of the critically endangered Iberian lynx (Lynx pardinus)
    Marina L Meli
    Clinical Laboratory, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 260, CH 8057 Zurich, Switzerland
    Vet Immunol Immunopathol 134:61-7. 2010
    ..It could result in epidemics that have the potential to eradicate the entire lynx population...
  21. pmc Quantitative TaqMan real-time PCR assays for gene expression normalisation in feline tissues
    Yvonne Kessler
    University of Zurich, Switzerland
    BMC Mol Biol 10:106. 2009
    ....
  22. pmc Identification, molecular characterization, and occurrence of two bovine hemoplasma species in Swiss cattle and development of real-time TaqMan quantitative PCR assays for diagnosis of bovine hemoplasma infections
    Marina L Meli
    Clinical Laboratory, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland
    J Clin Microbiol 48:3563-8. 2010
    ..wenyonii and exhibited higher M. wenyonii blood loads than animals with unrelated diseases and healthy animals. Coinfections may increase the pathogenicity and clinical significance of bovine hemoplasmosis...
  23. doi request reprint Importance of canine distemper virus (CDV) infection in free-ranging Iberian lynxes (Lynx pardinus)
    Marina L Meli
    Clinical Laboratory, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 260, CH 8057 Zurich, Switzerland
    Vet Microbiol 146:132-7. 2010
    ..To reduce the infectious pressure of CDV on this endangered population, a mass dog vaccination should be considered...
  24. pmc Worldwide occurrence of feline hemoplasma infections in wild felid species
    Barbara Willi
    Clinical Laboratory, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 260, 8057 Zurich, Switzerland
    J Clin Microbiol 45:1159-66. 2007
    ..In conclusion, 9 out of 15 wild felid species from three different continents were found to be infected with feline hemoplasmas. The effect of feline hemoplasma infections on wild felid populations needs to be further investigated...
  25. ncbi request reprint Reassessment of feline leukaemia virus (FeLV) vaccines with novel sensitive molecular assays
    Regina Hofmann-Lehmann
    Clinical Laboratory, Vetsuisse Faculty, University of Zurich, Winterthurerstr 260, CH 8057 Zurich, Switzerland
    Vaccine 24:1087-94. 2006
    ..The loads were significantly associated with the infection outcome. Thus, commonly used FeLV vaccines understood to be successful model antiretroviral vaccines protecting against FeLV-related diseases do not confer sterilizing immunity...
  26. ncbi request reprint Quantitation of feline leukaemia virus viral and proviral loads by TaqMan real-time polymerase chain reaction
    Ravi Tandon
    Clinical Laboratory, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 260, CH 8057 Zurich, Switzerland
    J Virol Methods 130:124-32. 2005
    ..Thus, for most effective detection of FeLV exposure and characterization of the infection in a cat, PCR assays are recommended as diagnostic tools...
  27. doi request reprint Quantification and molecular characterization of the feline leukemia virus A receptor
    A Katrin Helfer-Hungerbuehler
    Clinical Laboratory, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland
    Infect Genet Evol 11:1940-50. 2011
    ..The differential susceptibility of different species to FeLV could not be attributed to variations in the fTHTR1 sequence...
  28. ncbi request reprint Rapid detection of feline leukemia virus provirus integration into feline genomic DNA
    Valentino Cattori
    Clinical Laboratory, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 260, CH 8057 Zurich, Switzerland
    Mol Cell Probes 20:172-81. 2006
    ....
  29. doi request reprint In vitro inhibition of feline leukaemia virus infection by synthetic peptides derived from the transmembrane domain
    Eva Boenzli
    Clinical Laboratory, Faculty of Veterinary Medicine, University of Zurich, Zurich, Switzerland
    Antivir Ther 16:905-13. 2011
    ..We identified and synthetically produced 11 FeLV peptides and evaluated their potential to block FeLV infection in vitro...
  30. pmc Feline leukemia virus and other pathogens as important threats to the survival of the critically endangered Iberian lynx (Lynx pardinus)
    Marina L Meli
    Clinical Laboratory, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland
    PLoS ONE 4:e4744. 2009
    ..In this context, a retrospective survey on prevalence of selected feline pathogens in free-ranging lynxes was initiated...
  31. doi request reprint The innate antiviral immune system of the cat: molecular tools for the measurement of its state of activation
    Céline Robert-Tissot
    Clinical Laboratory, Vetsuisse Faculty, University of Zurich, Winterthurerstr 260, CH 8057 Zurich, Switzerland
    Vet Immunol Immunopathol 143:269-81. 2011
    ....
  32. doi request reprint Evaluation of the effect of short-term treatment with the integrase inhibitor raltegravir (Isentress) on the course of progressive feline leukemia virus infection
    Andrea Boesch
    Clinical Laboratory, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 260, 8057 Zurich, Switzerland Electronic address
    Vet Microbiol 175:167-78. 2015
    ..However, no complete control of viremia was achieved. Further investigations are needed to find an optimized treatment against FeLV. (250 words). ..
  33. doi request reprint Molecular characterization and virus neutralization patterns of severe, non-epizootic forms of feline calicivirus infections resembling virulent systemic disease in cats in Switzerland and in Liechtenstein
    Barbara Willi
    Clinical Laboratory, University of Zurich, Zurich, Switzerland Clinic for Small Animal Internal Medicine, University of Zurich, Zurich, Switzerland Electronic address
    Vet Microbiol 182:202-12. 2016
    ..In conclusion, clinicians should be aware of severe, non-epizootic forms of FCV infections with initial clinical presentations similar to VSD. ..
  34. pmc Identification, molecular characterization, and experimental transmission of a new hemoplasma isolate from a cat with hemolytic anemia in Switzerland
    Barbara Willi
    Clinical Laboratory, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 260, 8057 Zurich, Switzerland
    J Clin Microbiol 43:2581-5. 2005
    ..coccoides and M. haemomuris. A quantitative real-time PCR assay specific for this newly discovered agent was developed, which will be a prerequisite for the diagnosis of infections with the new hemoplasma isolate...