University of Geneva

Summary

Organization: University of Geneva
Country: Switzerland

Top Publications

  1. doi The nuclear pore complex: bridging nuclear transport and gene regulation
    Caterina Strambio-de-Castillia
    Department of Microbiology and Molecular Medicine, University of Geneva, 1 rue Michel Servet, CH 1211 Geneva, Switzerland
    Nat Rev Mol Cell Biol 11:490-501. 2010
  2. ncbi [Vaccinology update for 2008: what's new in Switzerland?]
    C A Siegrist
    Centre de vaccinologie et d immunologie néonatale, CMU, 1211 Geneve
    Rev Med Suisse 4:72-5. 2008
  3. doi An automated system for intracellular and intranuclear injection
    Ron C Hogg
    Department of Neurosciences Fondamentales, Medical Faculty, University of Geneva, Switzerland
    J Neurosci Methods 169:65-75. 2008
  4. ncbi Aging and lexical inhibition: the effect of orthographic neighborhood frequency in young and older adults
    Christelle Robert
    Department of Psychology, Universite Bordeaux 2, France
    J Gerontol B Psychol Sci Soc Sci 62:P340-2. 2007
  5. ncbi Long-term sealing ability of Pulp Canal Sealer, AH-Plus, GuttaFlow and Epiphany
    S Bouillaguet
    Department of Cariology and Endodontology, University of Geneva, Geneva, Switzerland
    Int Endod J 41:219-26. 2008
  6. ncbi The influence of action perception on object recognition: a developmental study
    Pierre Mounoud
    Department of Psychology, Universite de Geneve, Geneva, Switzerland
    Dev Sci 10:836-52. 2007
  7. ncbi Role of histone and DNA methylation in gene regulation
    Isabelle Vaillant
    Laboratory of Plant Genetics, University of Geneva, Sciences III, 30 Quai Ernest Ansermet, CH 1211 Geneva 4, Switzerland
    Curr Opin Plant Biol 10:528-33. 2007
  8. ncbi Gene-environment interactions in the skeletal response to nutrition and exercise during growth
    Jean Philippe Bonjour
    Division of Bone Diseases, WHO Collaborating Centre for Osteoporosis Prevention, Department of Rehabilitation and Geriatrics, University Hospitals of Geneva, Geneva 14, Switzerland
    Med Sport Sci 51:64-80. 2007
  9. ncbi The impact of pharmaceutical company funding on results of randomized trials of nicotine replacement therapy for smoking cessation: a meta-analysis
    Jean Francois Etter
    Institute of Social and Preventive Medicine, University of Geneva, Switzerland
    Addiction 102:815-22. 2007
  10. ncbi Anatomical modelling of the musculoskeletal system from MRI
    Benjamin Gilles
    MIRALab, University of Geneva, CH 1211 Geneva, Switzerland
    Med Image Comput Comput Assist Interv 9:289-96. 2006

Research Grants

  1. ROLE OF GLIL IN BASAL CELL CARCINOMA DEVELOPMENT
    Ariel Ruiz i Altaba; Fiscal Year: 2002
  2. FUNCTION OF THE GLI GENES IN SONIC SIGNALING
    Ariel Ruiz i Altaba; Fiscal Year: 2002
  3. FUNCTION OF THE GLI GENES IN SONIC HEDGEHOG SIGNALING
    Ariel Ruiz i Altaba; Fiscal Year: 2007
  4. Anthrax toxin-host cell interactions
    FRANCOISE VAN DER GOOT; Fiscal Year: 2004
  5. Gag and Cyclophillin in HIV-1 Replication
    Jeremy Luban; Fiscal Year: 2006
  6. Cyclophilin A Function in the Immune System
    Jeremy Luban; Fiscal Year: 2006
  7. Cyclophilin A Function in the Immune System
    Jeremy Luban; Fiscal Year: 2009
  8. GAG AND CYCLOPHILIN IN HIV1 REPLICATION
    Jeremy Luban; Fiscal Year: 2003
  9. MOLECULAR DESCRIPTION OF HIV1 GAG ASSEMBLY
    Jeremy Luban; Fiscal Year: 2000
  10. Molecular Description of HIV-1 GAG Assembly
    Jeremy Luban; Fiscal Year: 2003

Scientific Experts

Detail Information

Publications62

  1. doi The nuclear pore complex: bridging nuclear transport and gene regulation
    Caterina Strambio-de-Castillia
    Department of Microbiology and Molecular Medicine, University of Geneva, 1 rue Michel Servet, CH 1211 Geneva, Switzerland
    Nat Rev Mol Cell Biol 11:490-501. 2010
    ....
  2. ncbi [Vaccinology update for 2008: what's new in Switzerland?]
    C A Siegrist
    Centre de vaccinologie et d immunologie néonatale, CMU, 1211 Geneve
    Rev Med Suisse 4:72-5. 2008
    ..A source of information to be recommended without hesitation!..
  3. doi An automated system for intracellular and intranuclear injection
    Ron C Hogg
    Department of Neurosciences Fondamentales, Medical Faculty, University of Geneva, Switzerland
    J Neurosci Methods 169:65-75. 2008
    ..Moreover, we demonstrate that this method can also be successfully applied to inject zebrafish embryos and could be extended to other cell types...
  4. ncbi Aging and lexical inhibition: the effect of orthographic neighborhood frequency in young and older adults
    Christelle Robert
    Department of Psychology, Universite Bordeaux 2, France
    J Gerontol B Psychol Sci Soc Sci 62:P340-2. 2007
    ..These data are consistent with the assumption of an age-related decline in lexical inhibition and activation. The findings are discussed in the framework of visual word recognition and aging...
  5. ncbi Long-term sealing ability of Pulp Canal Sealer, AH-Plus, GuttaFlow and Epiphany
    S Bouillaguet
    Department of Cariology and Endodontology, University of Geneva, Geneva, Switzerland
    Int Endod J 41:219-26. 2008
    ..To evaluate the long-term sealing ability of four contemporary endodontic sealers [Pulp Canal Sealer (PCS), AH-Plus, GuttaFlow and Epiphany] using a fluid filtration technique...
  6. ncbi The influence of action perception on object recognition: a developmental study
    Pierre Mounoud
    Department of Psychology, Universite de Geneve, Geneva, Switzerland
    Dev Sci 10:836-52. 2007
    ..Implications of these results for the organization and development of conceptual knowledge are discussed...
  7. ncbi Role of histone and DNA methylation in gene regulation
    Isabelle Vaillant
    Laboratory of Plant Genetics, University of Geneva, Sciences III, 30 Quai Ernest Ansermet, CH 1211 Geneva 4, Switzerland
    Curr Opin Plant Biol 10:528-33. 2007
    ..Recent studies have refined our understanding of the biological significance of and the molecular mechanisms involved in the interplay between DNA and histone H3 methylation...
  8. ncbi Gene-environment interactions in the skeletal response to nutrition and exercise during growth
    Jean Philippe Bonjour
    Division of Bone Diseases, WHO Collaborating Centre for Osteoporosis Prevention, Department of Rehabilitation and Geriatrics, University Hospitals of Geneva, Geneva 14, Switzerland
    Med Sport Sci 51:64-80. 2007
    ..Identifying the functionally implicated genes interacting with mechanical loading and/or specific nutrients represents a formidable but hopefully not intractable challenge...
  9. ncbi The impact of pharmaceutical company funding on results of randomized trials of nicotine replacement therapy for smoking cessation: a meta-analysis
    Jean Francois Etter
    Institute of Social and Preventive Medicine, University of Geneva, Switzerland
    Addiction 102:815-22. 2007
    ..To assess whether source of funding affected the results of trials of nicotine replacement therapy (NRT) for smoking cessation...
  10. ncbi Anatomical modelling of the musculoskeletal system from MRI
    Benjamin Gilles
    MIRALab, University of Geneva, CH 1211 Geneva, Switzerland
    Med Image Comput Comput Assist Interv 9:289-96. 2006
    ..We validate our methods for the hip joint and the thigh (20 muscles, 4 bones) on 4 datasets: average error = 1.5 mm, computation time = 15 min...
  11. ncbi Cell growth control: little eukaryotes make big contributions
    C De Virgilio
    Département de Microbiologie et Médecine Moléculaire, Universite de Geneve, CMU, Geneva, Switzerland
    Oncogene 25:6392-415. 2006
    ..Given the unsurpassed resources available to yeast researchers, this simple eukaryote continues to contribute to our understanding of eukaryotic cell growth in general and TOR function in particular...
  12. ncbi Dynamics of composite polymerization mediates the development of cuspal strain
    S Bouillaguet
    Division of Cariology and Endodontology, School of Dental Medicine, University of Geneva, 19 Rue BarthElemy Menn, 1205 Geneva, Switzerland
    Dent Mater 22:896-902. 2006
    ..Our hypothesis was that composites with higher polymerization shrinkage should cause more cuspal strain as measured by ESPI...
  13. ncbi Deciphering the human nucleolar proteome
    Yohann Coute
    Biomedical Proteomics Research Group, Département de biologie structurale et bioinformatique, Centre Medical Universitaire, 1 rue Michel Servet, 1211 Geneva 14, Switzerland
    Mass Spectrom Rev 25:215-34. 2006
    ....
  14. ncbi The effects of beta1-adrenergic blockade on cardiovascular oxygen flow in normoxic and hypoxic humans at exercise
    Guido Ferretti
    Departement de Physiologie, Centre Medical Universitaire, Geneva, Switzerland
    Eur J Appl Physiol 95:250-9. 2005
    ..The two observed relationships between QvO(2) and SaO(2) apply to conditions of predominant sympathetic or vagal activation, respectively. Moving from one line to the other implies resetting of the cardiovascular regulation...
  15. ncbi [Diagnosis and management of mild bleeding disorders]
    P Fontana
    Service d angiologie et d hémostase, Departement de Medecine Interne, HUG, 1211 Geneve
    Rev Med Suisse 4:122-6. 2008
    ..Several pharmacological agents are available; however, before prophylactic administration of such drugs, a trade-off between their thrombotic risks and excessive bleeding should be made...
  16. doi Conscious emotional experience emerges as a function of multilevel, appraisal-driven response synchronization
    Didier Grandjean
    Swiss Center for Affective Sciences, University of Geneva, 7 rue des Battoirs, CH 1205 Geneva, Switzerland
    Conscious Cogn 17:484-95. 2008
    ..Third, we review recent neuroscience evidence that bolsters our claim of the central importance of the synchronization of neuronal assemblies at different levels of processing...
  17. ncbi [Medicine and the social sciences: a creative alliance]
    M de Coulon
    Rev Med Suisse 4:1062-5. 2008
  18. pmc Relationships between structural dynamics and functional kinetics in oligomeric membrane receptors
    Stuart J Edelstein
    European Molecular Biology Laboratory European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, UK
    Biophys J 98:2045-52. 2010
    ..Concerning published varphi(F) values underlying the conformational wave hypothesis for nicotinic receptors, we note that interpretations may be complicated by variations in the width of harmonic energy profiles...
  19. ncbi [Vaccine update 2009: questions around the safety of the influenza A (H1N1) vaccine]
    Claire Anne Siegrist
    Centre de vaccinologie et d immunologie néonatale, HUG et Faculté de médecine, 1211 Geneve 14
    Rev Med Suisse 6:67-70. 2010
    ..The huge number of questions sent by professionals to InfoVac experts (www.infovac.ch), and the expressed gratitude, allows for some hope...
  20. doi Short-term change in self-reported COPD symptoms after smoking cessation in an internet sample
    J F Etter
    Institute of Social and Preventive Medicine, University of Geneva, CMU, 1 rue Michel Servet, CH 1211 Geneva 4, Switzerland
    Eur Respir J 35:1249-55. 2010
    ..COPD is largely underdiagnosed and undertreated. Internet screening is reliable and may allow for the early detection of COPD symptoms at a large scale, in patients who may otherwise have no access to COPD case-finding efforts...
  21. doi Attentional networks efficiency in preterm children
    R Pizzo
    Child Clinical Neuropsychology Unit, University of Geneva, Geneva, Switzerland
    J Int Neuropsychol Soc 16:130-7. 2010
    ..We also observed a significantly higher correlation between the orienting and executive control networks in the preterm group, suggesting less differentiation of these two networks in this population...
  22. pmc Detection of genomic variation by selection of a 9 mb DNA region and high throughput sequencing
    Sergey I Nikolaev
    Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland
    PLoS ONE 4:e6659. 2009
    ....
  23. ncbi Full-mouth adhesive rehabilitation of a severely eroded dentition: the three-step technique. Part 2
    Francesca Vailati
    Dept of Fixed Prosthodontics and Occlusion, School of Dental Medicine, University of Geneva, Switzerland
    Eur J Esthet Dent 3:128-46. 2008
    ..A brief summary of the first step is also included...
  24. doi Inhibition of basal p38 or JNK activity enhances epithelial barrier function through differential modulation of claudin expression
    Fabio Carrozzino
    Dept of Cell Physiology and Metabolism, Faculty of Medicine, University of Geneva, Geneva, Switzerland
    Am J Physiol Cell Physiol 297:C775-87. 2009
    ....
  25. doi Endocytosis, asymmetric cell division, stem cells and cancer: unus pro omnibus, omnes pro uno
    Maximilian Fürthauer
    Department of Biochemistry, University of Geneva, Sciences II, CH 1211 Geneva 4, Switzerland
    Mol Oncol 3:339-53. 2009
    ..We review recent findings suggesting that an understanding of the relationship between endocytosis, asymmetric cell division, stem cells and cancer will be crucial to unravel the cell biological basis of tumourigenesis...
  26. ncbi Persistence and growth of faecal culturable bacterial indicators in water column and sediments of Vidy Bay, Lake Geneva, Switzerland
    John Pote
    University of Geneva, E A Forel Institute, 10 route de Suisse, 1290 Versoix, Switzerland
    J Environ Sci (China) 21:62-9. 2009
    ....
  27. pmc Compromised stability of DNA methylation and transposon immobilization in mosaic Arabidopsis epigenomes
    Jon Reinders
    Department of Plant Biology, University of Geneva, Sciences III, Geneva, Switzerland
    Genes Dev 23:939-50. 2009
    ..Such persistently "unstable" epigenetic states complicate linkage-based epigenomic mapping. Thus, future epigenomic analyses should consider possible genetic instabilities and alternative mapping strategies...
  28. doi Untangling the phylogeny of amoeboid protists
    Jan Pawlowski
    Department of Zoology and Animal Biology, University of Geneva, Geneva, Switzerland
    J Eukaryot Microbiol 56:16-25. 2009
    ..Finally, we highlight the interest of Amoebozoa and Rhizaria for understanding eukaryotic evolution and suggest that resolving their phylogenies will be among the main challenges for future phylogenomic analyses...
  29. doi Divergence in prevalence of mesiocclusion caused by different diagnostic criteria
    Christine Bettina Staudt
    Division of Orthodontics, Section de Médecine Dentaire, Faculte de Medecine, University of Geneva, Geneva, Switzerland
    Am J Orthod Dentofacial Orthop 135:323-7. 2009
    ..In addition to differences in ethnic background, sex, and age, inconsistency in diagnostic criteria might be important. Our aim was to investigate the prevalence of mesiocclusion in the same group by modifying the diagnostic criteria...
  30. doi Historical record of mercury contamination in sediments from the Babeni Reservoir in the Olt River, Romania
    Andrea Garcia Bravo
    Institut F A Forel, University of Geneva, Versoix, Switzerland
    Environ Sci Pollut Res Int 16:S66-75. 2009
    ..Preliminary analyses (unpublished) showed high Hg concentrations in the surface sediment of the Babeni Reservoir. One core was taken in the upstream Valcea Reservoir to provide a local background level of Hg concentrations in sediments...
  31. ncbi Ego involvement and effort: cardiovascular, electrodermal, and performance effects
    Guido H E Gendolla
    Department of Psychology, University of Geneva, Geneva, Switzerland
    Psychophysiology 42:595-603. 2005
    ....
  32. ncbi Internet-based smoking cessation programs
    Jean Francois Etter
    Institute of Social and Preventive Medicine, University of Geneva, CMU, Case Postale, CH 1211 Geneva 4, Switzerland
    Int J Med Inform 75:110-6. 2006
    ..To present a smoking cessation website and a reflection on the use of the Internet as a smoking cessation tool...
  33. ncbi Carbohydrate moieties in human secretory component
    G J Hughes
    Department of Medical Biochemistry at the Medical Center, Faculty of Medicine, University of Geneva, 1 rue Michel Servet, CH 1211, Geneva, Switzerland
    Biochim Biophys Acta 1434:86-93. 1999
    ..Three of these oligosaccharides are the major carbohydrate moieties in human lactoferrin. A possible biological role of the secretory component glycans in the protection of mucosal surfaces is discussed...
  34. ncbi Expression of alpha-1 proteinase inhibitor in human islet microvascular endothelial cells
    J Lou
    Department of Surgery, University Hospital, University of Geneva, Switzerland
    Diabetes 48:1773-8. 1999
    ..These results indicate that HI-MVEC exhibit some specific morphological and functional characteristics that differ from MVEC derived from other organs...
  35. ncbi Acetylcholine synthesis and quantal release reconstituted by transfection of mediatophore and choline acetyltranferase cDNAs
    A Bloc
    Pharmacologie, Centre Medical Universitaire, Geneve, Switzerland
    Eur J Neurosci 11:1523-34. 1999
    ....
  36. ncbi Anatomy teaching for medical undergraduates: general practice as a guideline? The brain
    J H Fasel
    Department of Morphology, University Medical Center, Geneva, Switzerland
    Clin Anat 12:115-9. 1999
    ..We also hope that this approach may serve as a model for the teaching of other basic sciences...
  37. ncbi Differential usage of two 5' splice sites in a complex exon generates additional protein sequence complexity in chicken CLIP-170 isoforms
    L Griparic
    Molecular Biophysics Program and Department of Biological Science, Florida State University, Tallahassee, FL, USA
    Biochim Biophys Acta 1449:119-24. 1999
    ..Differential usage of the 5'-splice junctions in this complex exon appears to be tissue- rather than isoform-specific...
  38. ncbi von Willebrand factor (vWf) as a plasma marker of endothelial activation in diabetes: improved reliability with parallel determination of the vWf propeptide (vWf:AgII)
    U M Vischer
    Department of Internal Medicine, HCU, Geneva, Switzerland
    Thromb Haemost 80:1002-7. 1998
    ....
  39. ncbi Influence of maternal antibodies on vaccine responses: inhibition of antibody but not T cell responses allows successful early prime-boost strategies in mice
    C A Siegrist
    W H O Collaborating Center for Neonatal Vaccinology, Department of Pathology, University of Geneva Medical School, Switzerland
    Eur J Immunol 28:4138-48. 1998
    ..It suggests that effective vaccine responses may be obtained earlier in presence of maternal antibodies through the use of appropriate immunization strategies using conventional or novel vaccines for early priming...
  40. ncbi Differential reactivity of brain microvascular endothelial cells to TNF reflects the genetic susceptibility to cerebral malaria
    J Lou
    Department of Anesthesiology, Pharmacology and Surgical Intensive Care, University Hospital, Geneva, Switzerland
    Eur J Immunol 28:3989-4000. 1998
    ..These results indicate that brain MVEC purified from CM-S and CM-R mice exhibit distinctive sensitivity to TNF This difference may be partly due to a differential regulation of TNF receptors and via distinct protein kinase pathways...
  41. ncbi Selective vulnerability of neocortical association areas in Alzheimer's disease
    P Giannakopoulos
    Department of Psychiatry, HUG Belle Idée, University of Geneva School of Medicine, Switzerland
    Microsc Res Tech 43:16-23. 1998
    ..Moreover, recent data on pathological correlates of apraxia in AD are examined in the light of the hypothesis of global corticocortical disconnection in this disorder...
  42. ncbi Cerebral cortex pathology in aging and Alzheimer's disease: a quantitative survey of large hospital-based geriatric and psychiatric cohorts
    P Giannakopoulos
    Department of Psychiatry, HUG Belle Idée, University of Geneva School of Medicine, Switzerland
    Brain Res Brain Res Rev 25:217-45. 1997
    ..These observations are discussed in the light of the hypothesis of global corticocortical disconnection and with respect to the notion of selective neuronal vulnerability in Alzheimer's disease...
  43. ncbi Haptic processing by the left hemisphere in a split-brain patient
    M Badan
    Faculty of Psychology and Educational Sciences, University of Geneva, Switzerland
    Neuropsychologia 35:1275-87. 1997
    ....
  44. ncbi The secalosides, novel tumor cell growth inhibitory glycosides from a pollen extract
    J C Jaton
    Department of Medical Biochemistry, University of Geneva, Switzerland
    J Nat Prod 60:356-60. 1997
    ..IC50 values obtained were about 5 micrograms/mouse for the secalosides and 1 microgram/mouse for 3 and 4...
  45. ncbi Haemostatic properties of human pulmonary and cerebral microvascular endothelial cells
    G E Grau
    Department of Anaesthesiology, University Hospital, Geneva, Switzerland
    Thromb Haemost 77:585-90. 1997
    ..It is concluded that MVEC display different haemostatic features depending on the tissue they come from and that lung MVEC from ARDS patients present a procoagulant profile when compared with those from controls...
  46. ncbi Post-stripping sclerodermiform dermatitis
    L E French
    Department Hospitalo Universitaire Romand de Dermatologie Geneva Lausanne, Geneva, Switzerland
    Arch Dermatol 135:1387-91. 1999
    ....
  47. ncbi Human calf microvascular compliance measured by near-infrared spectroscopy
    T Binzoni
    Departments of Physiology and Radiology, Faculty of Medicine, University of Geneva, 1211 Geneva 4, Switzerland
    J Appl Physiol (1985) 88:369-72. 2000
    ..However, by following the changes in oxy- and deoxyhemoglobin in the P range -16 to 100 mmHg, it appears to be possible to assess the characteristics of the vasomotor response of the arteriolar system...
  48. ncbi The parting of the endothelium: miracle, or simply a junctional affair?
    C Johnson-Leger
    Department of Pathology, Centre Medical Universitaire, Switzerland
    J Cell Sci 113:921-33. 2000
    ..Passage of the leukocyte across the endothelium appears to require delocalization of certain endothelial cell molecules and proteolytic degradation of junctional complexes...
  49. ncbi Mislocalization of flashes during smooth pursuit hardly depends on the lighting conditions
    Dirk Kerzel
    Faculte de Psychologie et des Sciences de l Education, Universite de Geneve, 40 bd du Pont d Arve, CH 1205 Geneve, Switzerland
    Vision Res 46:1145-54. 2006
    ..We conclude that although the lighting conditions do influence the localization errors under some circumstances, it is certainly not so that such errors are absent whenever the experiment is conducted in the dark...
  50. ncbi Nitric oxide production within rat urothelial cells
    D Mastrangelo
    Urology Clinic, Department of Surgery, Geneva University Hospital, Switzerland
    J Urol 170:1409-14. 2003
    ..We investigated endogenous NO production in the proximal half of the rat ureter, localized its cellular source, characterized the NOS isoforms involved and assessed the impact of NO on ureteral motility...
  51. ncbi Cell biology. Apoptosis--the calcium connection
    Nicolas Demaurex
    Department of Physiology, University of Geneva Medical Center, Geneva, Switzerland
    Science 300:65-7. 2003
  52. ncbi The Q motif: a newly identified motif in DEAD box helicases may regulate ATP binding and hydrolysis
    N Kyle Tanner
    Departement de Biochimie Medicale, Centre Medical Universitaire, 1, rue Michel Servet, 1211 Geneva 4, Switzerland
    Mol Cell 11:127-38. 2003
    ..These results are consistent with computer studies of the solved crystal structures...
  53. ncbi Retinoids induce lumen morphogenesis in mammary epithelial cells
    Roberto Montesano
    Department of Morphology, University of Geneva Medical Center, CH 1211 Geneva 4, Switzerland
    J Cell Sci 115:4419-31. 2002
    ..Collectively, our results provide evidence that RA promotes lumen formation by mammary epithelial cells in vitro and suggest that it plays a similar role during mammary gland development in vivo...
  54. ncbi Physicochemical aspects of lead bioaccumulation by Chlorella vulgaris
    Vera I Slaveykova
    Analytical and Biophysical Environmental Chemistry, University of Geneva, Switzerland
    Environ Sci Technol 36:969-75. 2002
    ..67) M(-1) at pH 6. Results were discussed within the perspective of the free ion activity and biotic ligand models...
  55. ncbi The use of digital dermoscopy for the follow-up of congenital nevi: a pilot study
    R P Braun
    Pigmented Skin Lesion Unit, Department of Dermatology, University Hospital Geneva, Geneva, Switzerland
    Pediatr Dermatol 18:277-81. 2001
    ..We showed the feasibility of follow-up of congenital nevi using digital dermoscopy. Furthermore, we identified three different patterns as well as some typical structures seen in congenital nevi by DD...
  56. ncbi Coexistence in a predator-prey system
    M Droz
    Département de Physique Théorique, Universite de Geneve, quai E Ansermet 24, 1211 Geneve 4, Switzerland
    Phys Rev E Stat Nonlin Soft Matter Phys 63:051909. 2001
    ..We demonstrate that the probability of arriving at one of the above states depends on the initial densities of the prey and predator populations, the amount of cover, and the way it is spatially distributed...
  57. ncbi Raft membrane domains: from a liquid-ordered membrane phase to a site of pathogen attack
    F G van der Goot
    Department of Biochemistry, University of Geneva, 1211 Geneva, 30 quai E Ansermet, Switzerland
    Semin Immunol 13:89-97. 2001
    ..Elucidation of these interactions requires a detailed understanding raft structure and dynamics...
  58. pmc Raft-partitioning of the ubiquitin ligases Cbl and Nedd4 upon IgE-triggered cell signaling
    F Lafont
    Max Planck Institute of Molecular Cell Biology and Genetics, Pfotenhauerstrasse 110, D 01307 Dresden, Germany
    Proc Natl Acad Sci U S A 98:3180-4. 2001
    ..Because Cbl is known to interact with the FcepsilonRI signaling complex, ubiquitination is likely to be an important parameter regulating IgE-triggered signaling occurring in rafts...
  59. ncbi [Respiratory sleep disorders in the elderly]
    J P Janssens
    Departement de Geriatrie, Hopitaux Universitaires de Geneve
    Rev Med Suisse Romande 120:869-79. 2000
    ..SRBD should be considered as a possible cause of "reversible dementia" and sought for in the presence of daytime somnolence, delirium, or unexplained right-sided heart failure in older patients...
  60. ncbi Human and Xenopus cingulin share a modular organization of the coiled-coil rod domain: predictions for intra- and intermolecular assembly
    S Citi
    Department of Molecular Biology, University of Geneva, Geneva, 1205, Switzerland
    J Struct Biol 131:135-45. 2000
    ..Cingulin mRNA ( approximately 5.2 kb) was detected by Northern blotting in epithelial tissues. A human cingulin EST was mapped to chromosome 1q21 using the UniGene database...
  61. pmc Vasopressin-induced von Willebrand factor secretion from endothelial cells involves V2 receptors and cAMP
    J E Kaufmann
    Division of Clinical Biochemistry, Geneva, Switzerland Research Institute for Molecular Pharmacology, Berlin, Germany
    J Clin Invest 106:107-16. 2000
    ..They also demonstrate functional expression of V2R in endothelial cells, and provide a cellular mechanism for the hemostatic effects of DDAVP...
  62. ncbi Dynamic changes in nuclear architecture during mitosis: on the role of protein phosphorylation in spindle assembly and chromosome segregation
    E A Nigg
    Department of Molecular Biology, Sciences II, University of Geneva, 30, Quai Ernest Ansermet, Geneva 4, CH 1211, Switzerland
    Exp Cell Res 229:174-80. 1996
    ..This observation hints at the existence of a checkpoint linking Cdc2 activation to the presence of functional centrosomes...

Research Grants40

  1. ROLE OF GLIL IN BASAL CELL CARCINOMA DEVELOPMENT
    Ariel Ruiz i Altaba; Fiscal Year: 2002
    ..In addition, understanding how deregulation of the Shh signaling pathway and Gli1 function lead to BCC formation, will shed light into the normal role of this gene in follicle development. ..
  2. FUNCTION OF THE GLI GENES IN SONIC SIGNALING
    Ariel Ruiz i Altaba; Fiscal Year: 2002
    ....
  3. FUNCTION OF THE GLI GENES IN SONIC HEDGEHOG SIGNALING
    Ariel Ruiz i Altaba; Fiscal Year: 2007
    ..In addition, the knowledge of how the SHH-GLI pathway affects brain precursors will help our understanding of how brain tumors arise, an area of research covered under a different, yet related, project in the laboratory. ..
  4. Anthrax toxin-host cell interactions
    FRANCOISE VAN DER GOOT; Fiscal Year: 2004
    ..abstract_text> ..
  5. Gag and Cyclophillin in HIV-1 Replication
    Jeremy Luban; Fiscal Year: 2006
    ..These immunologic abnormalities would be expected to contribute to HIV-1 replication and pathogenesis. ..
  6. Cyclophilin A Function in the Immune System
    Jeremy Luban; Fiscal Year: 2006
    ..New information concerning these basic biological processes will help understand the etiology of such diseases as asthma and AIDS, and, therefore, is critical for the development of much-needed medical therapies. ..
  7. Cyclophilin A Function in the Immune System
    Jeremy Luban; Fiscal Year: 2009
    ..New information concerning these basic biological processes will help understand the etiology of such diseases as asthma and AIDS, and, therefore, is critical for the development of much-needed medical therapies. ..
  8. GAG AND CYCLOPHILIN IN HIV1 REPLICATION
    Jeremy Luban; Fiscal Year: 2003
    ..4) To gain biochemical evidence for the function of CyPA for HIV-1 replication, including a test of the hypothesis that this cellular protein acts by destabilizing HIV-1 cores, thereby promoting disassembly in the newly infected cell. ..
  9. MOLECULAR DESCRIPTION OF HIV1 GAG ASSEMBLY
    Jeremy Luban; Fiscal Year: 2000
    ..The role of viral RNA in Gag multimerization will also be studied. Finally, a selection of techniques will be used to assess how mutations affecting Gag multimerization impact upon HIV-1 infectivity in vitro. ..
  10. Molecular Description of HIV-1 GAG Assembly
    Jeremy Luban; Fiscal Year: 2003
    ..Experiments proposed here will promote understanding of HIV-1 replication mechanisms and may contribute to development of new antiviral agents. ..