University of Basel

Summary

Organization: University of Basel
Country: Switzerland

Top Publications

  1. ncbi News in autoimmune disease
    A Tyndall
    Department of Rheumatology, University of Basel Kantonsspital
    Schweiz Med Wochenschr 130:113-8. 2000
  2. ncbi Stem cells and rheumatology: update on adult stem cell therapy in autoimmune diseases
    Alan Tyndall
    University Hospital, Basle, Switzerland
    Arthritis Rheum 55:521-5. 2006
  3. ncbi Bone marrow mesenchymal stromal cells (BM-MSCs) from healthy donors and auto-immune disease patients reduce the proliferation of autologous- and allogeneic-stimulated lymphocytes in vitro
    C Bocelli-Tyndall
    Department of Rheumatology, University of Basel, Basel, Switzerland
    Rheumatology (Oxford) 46:403-8. 2007
  4. ncbi Human articular chondrocytes suppress in vitro proliferation of anti-CD3 activated peripheral blood mononuclear cells
    Chiara Bocelli-Tyndall
    Department of Rheumatology, University of Basel, Felix Plattel Spital, Burgfelderstrasse 101, 4012 Basel, Switzerland
    J Cell Physiol 209:732-4. 2006
  5. pmc Clinical risk assessment of organ manifestations in systemic sclerosis: a report from the EULAR Scleroderma Trials And Research group database
    U A Walker
    Department of Rheumatology, Basle University, Felix Platter Spital, Burgfelderstrasse 101, Basel 4012, Switzerland
    Ann Rheum Dis 66:754-63. 2007
  6. pmc Immunomodulatory properties of mesenchymal stem cells: a review based on an interdisciplinary meeting held at the Kennedy Institute of Rheumatology Division, London, UK, 31 October 2005
    Alan Tyndall
    Rheumatology, University Hospital Basel, Felix Platter Spital, Burgfelderstrasse 101, Basel, CH 4012, Switzerland
    Arthritis Res Ther 9:301. 2007
  7. ncbi Adult stem cell treatment of scleroderma
    Alan Tyndall
    Department of Rheumatology, University of Basel, Switzerland
    Curr Opin Rheumatol 19:604-10. 2007
  8. doi Rheumatic conditions in human immunodeficiency virus infection
    U A Walker
    Department of Rheumatology, Basel University, Basel, Switzerland
    Rheumatology (Oxford) 47:952-9. 2008
  9. ncbi Why do we need noncommercial, investigator-initiated clinical trials?
    Alan Tyndall
    Department of Rheumatology, University of Basel, Switzerland
    Nat Clin Pract Rheumatol 4:354-5. 2008
  10. doi Chronic GVHD as an autoimmune disease
    Alan Tyndall
    Department of Rheumatology, University of Basel, Felix Platter Spital, Burfelderstrasse 101, 4012 Basel, Switzerland
    Best Pract Res Clin Haematol 21:281-9. 2008

Detail Information

Publications38

  1. ncbi News in autoimmune disease
    A Tyndall
    Department of Rheumatology, University of Basel Kantonsspital
    Schweiz Med Wochenschr 130:113-8. 2000
    ..We must not forget the aim of improving quality of life for our patients, and not just improvement of immunological laboratory parameters...
  2. ncbi Stem cells and rheumatology: update on adult stem cell therapy in autoimmune diseases
    Alan Tyndall
    University Hospital, Basle, Switzerland
    Arthritis Rheum 55:521-5. 2006
  3. ncbi Bone marrow mesenchymal stromal cells (BM-MSCs) from healthy donors and auto-immune disease patients reduce the proliferation of autologous- and allogeneic-stimulated lymphocytes in vitro
    C Bocelli-Tyndall
    Department of Rheumatology, University of Basel, Basel, Switzerland
    Rheumatology (Oxford) 46:403-8. 2007
    ....
  4. ncbi Human articular chondrocytes suppress in vitro proliferation of anti-CD3 activated peripheral blood mononuclear cells
    Chiara Bocelli-Tyndall
    Department of Rheumatology, University of Basel, Felix Plattel Spital, Burgfelderstrasse 101, 4012 Basel, Switzerland
    J Cell Physiol 209:732-4. 2006
    ..To investigate whether mature human articular chondrocytes (AC) exhibit an antiproliferative effect on activated peripheral blood mononuclear cells (PBMC) and to compare this effect with other cells of mesenchymal origin...
  5. pmc Clinical risk assessment of organ manifestations in systemic sclerosis: a report from the EULAR Scleroderma Trials And Research group database
    U A Walker
    Department of Rheumatology, Basle University, Felix Platter Spital, Burgfelderstrasse 101, Basel 4012, Switzerland
    Ann Rheum Dis 66:754-63. 2007
    ..In order to better understand the vascular, immunological and fibrotic processes of SSc and to guide its treatment, the EULAR Scleroderma Trials And Research (EUSTAR) group was formed in June 2004...
  6. pmc Immunomodulatory properties of mesenchymal stem cells: a review based on an interdisciplinary meeting held at the Kennedy Institute of Rheumatology Division, London, UK, 31 October 2005
    Alan Tyndall
    Rheumatology, University Hospital Basel, Felix Platter Spital, Burgfelderstrasse 101, Basel, CH 4012, Switzerland
    Arthritis Res Ther 9:301. 2007
    ..This review summarizes the findings of a 1-day meeting devoted to the subject with the aim of coordinating efforts...
  7. ncbi Adult stem cell treatment of scleroderma
    Alan Tyndall
    Department of Rheumatology, University of Basel, Switzerland
    Curr Opin Rheumatol 19:604-10. 2007
    ....
  8. doi Rheumatic conditions in human immunodeficiency virus infection
    U A Walker
    Department of Rheumatology, Basel University, Basel, Switzerland
    Rheumatology (Oxford) 47:952-9. 2008
    ..Thus, rheumatic diseases and asymptomatic immune phenomena remain prevalent in HIV-infected persons even after the widespread implementation of highly active anti-retroviral therapy...
  9. ncbi Why do we need noncommercial, investigator-initiated clinical trials?
    Alan Tyndall
    Department of Rheumatology, University of Basel, Switzerland
    Nat Clin Pract Rheumatol 4:354-5. 2008
  10. doi Chronic GVHD as an autoimmune disease
    Alan Tyndall
    Department of Rheumatology, University of Basel, Felix Platter Spital, Burfelderstrasse 101, 4012 Basel, Switzerland
    Best Pract Res Clin Haematol 21:281-9. 2008
    ....
  11. doi Geographical variation of disease manifestations in systemic sclerosis: a report from the EULAR Scleroderma Trials and Research (EUSTAR) group database
    U A Walker
    Felix Platter Spital, Basel, Switzerland
    Ann Rheum Dis 68:856-62. 2009
    ..The aetiology is unknown. Genetic and environmental susceptibility factors have been implicated. It is unknown whether disease presentation varies within Europe...
  12. doi Human bone marrow mesenchymal stem cells and chondrocytes promote and/or suppress the in vitro proliferation of lymphocytes stimulated by interleukins 2, 7 and 15
    C Bocelli-Tyndall
    Institute of Surgical Research and Hospital Management and Department of Biomedicine, University Hospital Basel, Basel, Switzerland
    Ann Rheum Dis 68:1352-9. 2009
    ....
  13. doi Imaging tools for the clinical assessment of idiopathic inflammatory myositis
    Ulrich A Walker
    Department of Rheumatology, Basel University, Basel, Switzerland
    Curr Opin Rheumatol 20:656-61. 2008
    ..To summarize advances in the imaging of idiopathic inflammatory myopathies...
  14. doi Multipotent mesenchymal stromal cells for autoimmune diseases: teaching new dogs old tricks
    A Tyndall
    Department of Rheumatology, University of Basel, University Rheumatology Clinic, Basel, Switzerland
    Bone Marrow Transplant 43:821-8. 2009
    ..Multidisciplinary groups are collaborating to ensure maximal use of available resources to establish the place, if any, of MSC in the treatment of AD...
  15. doi Cellular therapy of systemic lupus erythematosus
    A Tyndall
    Department of Rheumatology, University of Basel, Felix Platter Hospital, 4012, Basel, Switzerland
    Lupus 18:387-93. 2009
    ..Mesenchymal stem cells are in an exploratory phase for the treatment of acute autoimmune disease including SLE. The principle is that they home to inflammed tissue and exert an antiinflammatory paracrine effect...
  16. doi [Scleroderma and fibrosing diseases]
    U A Walker
    Rheumatologische Universitätsklinik, Universitat Basel, Burgfelderstrasse 101, Basel, Switzerland
    Z Rheumatol 68:312-9. 2009
    ..The diagnostic relevance of a histopathological diagnosis of fibrosing diseases varies and ranges from a disease-supporting to a disease-defining value...
  17. doi Future targets in the management of systemic sclerosis
    A Tyndall
    Department of Rheumatology, Felix Platter Hospital, Basel, Switzerland
    Rheumatology (Oxford) 48:iii49-53. 2009
    ....
  18. doi Erectile dysfunction in systemic sclerosis
    U A Walker
    Department of Rheumatology, Basel University, Basel, Switzerland
    Ann Rheum Dis 68:1083-5. 2009
    ..When intracavernous injections of prostaglandin E1 (alprostadil) are ineffective, the implantation of a penile prosthesis may be considered. Complex treatment options may require the involvement of urology...
  19. ncbi Autologous hematopoietic stem cell transplantation for autoimmune diseases
    Alan Tyndall
    Department of Rheumatology, University Hospital, Basel, Switzerland
    Acta Haematol 114:239-47. 2005
    ..Basic science programs are also being undertaken to study the immunological mechanisms underlying the clinical events observed...
  20. pmc Systemic sclerosis in Europe: first report from the EULAR Scleroderma Trials And Research (EUSTAR) group database
    A Tyndall
    Department of Rheumatology, Felix Platter Spital, CH 4012, Basel, Switzerland
    Ann Rheum Dis 64:1107. 2005
  21. pmc Immune ablation and stem-cell therapy in autoimmune disease. Clinical experience
    A Tyndall
    Department of Rheumatology, University of Basel, Basel, Switzerland
    Arthritis Res 2:276-80. 2000
    ..No one regimen was clearly superior to another, with a trend toward more infectious complications with more intense regimens. Prospective, controlled randomized trials are indicated and being planned...
  22. ncbi [Results of neurorehabilitation. An outcome study 20 months after stroke]
    M Frank
    Geriatrisches Kompetenzzentrum Felix Platter Spital, Basel
    Praxis (Bern 1994) 89:1799-808. 2000
    ..This seems to be true for more severely disabled patients, too, if rehabilitative therapies, home services and day care are consequently provided...
  23. ncbi Immunoablation and haemopoietic stem cell transplantation for severe autoimmune disease with special reference to systemic lupus erythematosus
    A Tyndall
    University Department of Rheumatology, Felix Platter Spital, Burgfelderstrasses 101, Basal 4012, Switzerland
    Lupus 10:214-5. 2001
    ..Randomised, prospective controlled phase III trials are desired, but by consensus, more phase I and II data is required to plan the optimal protocol...
  24. pmc Haemopoietic stem cell transplantation in the treatment of severe autoimmune diseases 2000
    A Tyndall
    Department of Rheumatology, University Hospital, Basel, Switzerland
    Ann Rheum Dis 60:702-7. 2001
    ..Further phase I and II data are required in SLE, JIA, and vasculitis. The need for continuing collection of all cases after mobilisation by the standardised EBMT and IBMTR data forms was emphasised...
  25. ncbi [Particle disease. Is tribology a topic in revision surgery?]
    R Elke
    Orthopadische Universitatsklinik, Felix Platter Spital, Burgfelderstrasse 101, CH 4012 Basel
    Orthopade 30:258-65. 2001
    ..Advantages and downsides regarding particle generation and higher standards of precision in positioning the components are discussed...
  26. ncbi [Acetabulum revision. Classifications and treatment possibilities]
    R Elke
    Orthopadische Universitatsklinik, Felix Platter Spital, Burgfelderstrasse 101, CH 4012 Basel
    Orthopade 30:266-72. 2001
    ..After a mean follow-up of 7.1 years, not a single cup had to be revised for aseptic loosening. The 9.5% dislocations were due to abductor insufficiencies because of trochanteric pathologies or muscular alterations from former approaches...
  27. ncbi [Shaft revision. Classification and treatment]
    R Elke
    Orthopadische Universitatsklinik, Felix Platter Spital, Burgfelderstrasse 101, CH 4012 Basel
    Orthopade 30:280-6. 2001
    ..Type 4 defects are reconstructed with a combination of a revision stem and an allograft...
  28. ncbi [Modular shafts in hip prosthesis revision surgery]
    H U Cameron
    Orthopaedic and Arthritic Institute, 318 43 Wellesley St E, Toronto, ON M4Y 1H1, Canada
    Orthopade 30:287-93. 2001
    ..To date no particular downside has been noted as a result of the use of a modular stem...
  29. ncbi [Cement removal with ultrasound in revision or total hip prosthesis]
    C A Schwaller
    Orthopädische Universitätsklinik Basel, Felix Platter Spital, Burgfelderstrasse 101, CH 4012 Basel, Schweiz
    Orthopade 30:310-6. 2001
    ..We present an ultrasonic device for rapid cement removal with minimum risk of trauma to the fragile femoral bone. The technique of cement removal with ultrasound is described and problems and risks are addressed...
  30. ncbi Autologous hematopoietic stem cell transplantation for severe autoimmune disease with special reference to rheumatoid arthritis
    A Tyndall
    Department of Rheumatology, University of Basel, Switzerland
    J Rheumatol Suppl 64:5-7. 2001
    ..Randomized, prospective controlled phase III trials have begun in SSc and will soon commence in RA and multiple sclerosis. More phase I and II data are required for systemic lupus erythematosus and juvenile idiopathic arthritis...
  31. ncbi Posterior tibial tendon dysfunction and MR imaging in rheumatoid arthritis
    Paul Hasler
    Rheumatology University Clinic, Felix Platter Spital and University Hospital, Basel, Switzerland
    Rheumatol Int 22:38-40. 2002
    ..This case illustrates a pitfall in MRI imaging with potential diagnostic and therapeutic consequences...
  32. ncbi [When forgetting is not possible]
    M I von Muehlenen
    Medizinische Universitäts Poliklinik, Kantonsspital Basel, Switzerland
    Praxis (Bern 1994) 92:1141-4. 2003
  33. ncbi Haematopoietic stem cell transplantation for the treatment of systemic sclerosis and other autoimmune disorders
    Alan Tyndall
    Department of Rheumatology, University of Basle, Felix Platter Spital, CH 4012, Basle, Switzerland
    Expert Opin Biol Ther 3:1041-9. 2003
    ..It is hypothesised that this results in fewer autoinflammatory and unwanted stimulatory signals to other systems such as vascular endothelium and fibroblasts, and these mechanisms are currently under study...
  34. ncbi [Rheumatoid arthritis--clinical picture and important differential diagnoses]
    Thomas Vogt
    Rheumatologische Universitätsklinik, Felix Platter Spital und Universitätsspital, Basel
    Ther Umsch 62:265-8. 2005
    ..Diseases to be separated from rheumatoid are other arthritides of autoimmune origin, the cristal arthropathies, vasculitides, septic and parainfectious arthritides, osteoarthritis, and paraneoplastic syndromes...
  35. ncbi [Rheumatoid arthritis--pearls and myths]
    A Tyndall
    Rheumatologische Universitätsklinik, Felix Platter Spital, Basel
    Ther Umsch 62:269-71. 2005
  36. ncbi [Rheumatoid arthritis--new perspectives in its diagnosis]
    M I von Mühlenen
    Rheumatologische Universitätspoliklinik, Felix Platter Spital, Basel
    Ther Umsch 62:273-9. 2005
    ..Traditional and new diagnostic tools like ultrasound and MRI are reviewed and analysed in the perspective of early recognition of disease...
  37. pmc Haematopoietic stem cell transplantation in the treatment of severe autoimmune disease: results from phase I/II studies, prospective randomized trials and future directions
    A Tyndall
    Department of Rheumatology, University Hospital Basle, Basle, Switzerland
    Clin Exp Immunol 141:1-9. 2005
    ..In those who relapsed, many responded to agents which pre transplant had been ineffective. The study of immune reconstitution and gene expression pre and post HSCT is being undertaken to further understand the mechanism of autoimmunity...
  38. doi [Oral anticoagulation in the elderly - practical aspects and risk-benefit trade-off in atrial fibrillation]
    M Frank
    Geriatrisches Kompetenzzentrum, Felix Platter Spital, Basel
    Praxis (Bern 1994) 99:429-35. 2010
    ..In the end, the decision to start or withhold anticoagulation has to be taken individually...