Affiliation: Swiss Federal Institute of Technology
- Bunched, the Drosophila homolog of the mammalian tumor suppressor TSC-22, promotes cellular growthSilvia Gluderer
Institute of Molecular Systems Biology, ETH Zurich, Wolfgang Pauli Str, 16, 8093 Zurich, Switzerland
BMC Dev Biol 8:10. 2008..Possible redundancy among the members of the TSC-22/Dip/Bun protein family complicates a genetic analysis. In Drosophila, all proteins homologous to the TSC-22/Dip/Bun family members are derived from a single locus called bunched (bun)...
- Madm (Mlf1 adapter molecule) cooperates with Bunched A to promote growth in DrosophilaSilvia Gluderer
Institute of Molecular Systems Biology, ETH Zurich, Wolfgang Pauli Strasse 16, 8093 Zurich, Switzerland
J Biol 9:9. 2010..In Drosophila, the long isoform Bunched A (BunA) acts as a growth promoter, but how BunA controls growth has remained obscure...
- The Drosophila homolog of human tumor suppressor TSC-22 promotes cellular growth, proliferation, and survivalXiaodong Wu
Cutaneous Biology Research Center and Massachusetts General Hospital Cancer Center, Massachusetts General Hospital Harvard Medical School, Charlestown, MA 02129, USA
Proc Natl Acad Sci U S A 105:5414-9. 2008..We speculate that reduced TSC22D1 expression generally reduces cellular fitness and only contributes to carcinogenesis in specific tissue environments...