Liam O'Mahony

Summary

Country: Switzerland

Publications

  1. doi request reprint Novel immunotherapeutic approaches for allergy and asthma
    Liam O'Mahony
    Swiss Institute of Allergy and Asthma Research, University of Zurich, Davos, Switzerland
    Autoimmunity 43:493-503. 2010
  2. pmc Research needs in allergy: an EAACI position paper, in collaboration with EFA
    Nikolaos G Papadopoulos
    Allergy Department, 2nd Pediatric Clinic, University of Athens, Athens, Greece
    Clin Transl Allergy 2:21. 2012
  3. pmc Bifidobacterium animalis AHC7 protects against pathogen-induced NF-κB activation in vivo
    David O'Mahony
    Alimentary Health Ltd, National University of Ireland, Cork, Ireland
    BMC Immunol 11:63. 2010
  4. pmc Functional modulation of human intestinal epithelial cell responses by Bifidobacterium infantis and Lactobacillus salivarius
    Ann M O'Hara
    Alimentary Pharmabiotic Centre, University College Cork, National University of Ireland, Cork, Ireland
    Immunology 118:202-15. 2006
  5. ncbi request reprint Prevention of allergy by a recombinant multi-allergen vaccine with reduced IgE binding and preserved T cell epitopes
    Fariba Karamloo
    Swiss Institute of Allergy and Asthma Research SIAF, Davos, Switzerland
    Eur J Immunol 35:3268-76. 2005
  6. pmc Immunomodulation by Bifidobacterium infantis 35624 in the murine lamina propria requires retinoic acid-dependent and independent mechanisms
    Patrycja Konieczna
    Swiss Institute of Allergy and Asthma Research SIAF, University of Zurich, Davos, Switzerland
    PLoS ONE 8:e62617. 2013
  7. doi request reprint Loss of vagal anti-inflammatory effect: in vivo visualization and adoptive transfer
    Caitlin O'Mahony
    Alimentary Pharmabiotic Centre, National University of Ireland, Cork, Ireland
    Am J Physiol Regul Integr Comp Physiol 297:R1118-26. 2009
  8. doi request reprint Bifidobacterium infantis 35624 administration induces Foxp3 T regulatory cells in human peripheral blood: potential role for myeloid and plasmacytoid dendritic cells
    Patrycja Konieczna
    Swiss Institute of Allergy and Asthma Research SIAF, University of Zurich, Zurich, Switzerland
    Gut 61:354-66. 2012
  9. doi request reprint Role of Treg in immune regulation of allergic diseases
    Oscar Palomares
    Swiss Institute of Allergy and Asthma Research SIAF, University of Zurich, Davos, Switzerland
    Eur J Immunol 40:1232-40. 2010
  10. pmc In vivo switch to IL-10-secreting T regulatory cells in high dose allergen exposure
    Flurina Meiler
    Swiss Institute of Allergy and Asthma Research, University of Zurich, 7270 Davos, Switzerland
    J Exp Med 205:2887-98. 2008

Collaborators

Detail Information

Publications55

  1. doi request reprint Novel immunotherapeutic approaches for allergy and asthma
    Liam O'Mahony
    Swiss Institute of Allergy and Asthma Research, University of Zurich, Davos, Switzerland
    Autoimmunity 43:493-503. 2010
    ..This review will discuss novel approaches to the management of allergy and asthma by targeting the T regulatory cell via modulation of the commensal microbiota and allergen-SIT...
  2. pmc Research needs in allergy: an EAACI position paper, in collaboration with EFA
    Nikolaos G Papadopoulos
    Allergy Department, 2nd Pediatric Clinic, University of Athens, Athens, Greece
    Clin Transl Allergy 2:21. 2012
    ..Active involvement of all stakeholders, including Patient Organizations and policy makers are necessary to achieve the aims emphasized herein...
  3. pmc Bifidobacterium animalis AHC7 protects against pathogen-induced NF-κB activation in vivo
    David O'Mahony
    Alimentary Health Ltd, National University of Ireland, Cork, Ireland
    BMC Immunol 11:63. 2010
    ..The aim of this study was to investigate the potential molecular and cellular mechanisms underpinning the Bifidobacterium animalis AHC7 protective effect...
  4. pmc Functional modulation of human intestinal epithelial cell responses by Bifidobacterium infantis and Lactobacillus salivarius
    Ann M O'Hara
    Alimentary Pharmabiotic Centre, University College Cork, National University of Ireland, Cork, Ireland
    Immunology 118:202-15. 2006
    ..infantis or L. salivarius, these commensal bacteria exert immunomodulatory effects on intestinal immune cells that mediate host responses to flagellin and enteric pathogens...
  5. ncbi request reprint Prevention of allergy by a recombinant multi-allergen vaccine with reduced IgE binding and preserved T cell epitopes
    Fariba Karamloo
    Swiss Institute of Allergy and Asthma Research SIAF, Davos, Switzerland
    Eur J Immunol 35:3268-76. 2005
    ....
  6. pmc Immunomodulation by Bifidobacterium infantis 35624 in the murine lamina propria requires retinoic acid-dependent and independent mechanisms
    Patrycja Konieczna
    Swiss Institute of Allergy and Asthma Research SIAF, University of Zurich, Davos, Switzerland
    PLoS ONE 8:e62617. 2013
    ..infantis-fed mice. Thus, CD103(+)RALDH(+) LP dendritic cells are important cellular targets for microbiota-associated effects on mucosal immunoregulation...
  7. doi request reprint Loss of vagal anti-inflammatory effect: in vivo visualization and adoptive transfer
    Caitlin O'Mahony
    Alimentary Pharmabiotic Centre, National University of Ireland, Cork, Ireland
    Am J Physiol Regul Integr Comp Physiol 297:R1118-26. 2009
    ..The proinflammatory effect of vagotomy is transferable using splenic T cells and highlights a previously unappreciated cellular mechanism for linking central parasympathetic processes with mucosal inflammation and immune homeostasis...
  8. doi request reprint Bifidobacterium infantis 35624 administration induces Foxp3 T regulatory cells in human peripheral blood: potential role for myeloid and plasmacytoid dendritic cells
    Patrycja Konieczna
    Swiss Institute of Allergy and Asthma Research SIAF, University of Zurich, Zurich, Switzerland
    Gut 61:354-66. 2012
    ..Intestinal homoeostasis is dependent on immunological tolerance to the microbiota...
  9. doi request reprint Role of Treg in immune regulation of allergic diseases
    Oscar Palomares
    Swiss Institute of Allergy and Asthma Research SIAF, University of Zurich, Davos, Switzerland
    Eur J Immunol 40:1232-40. 2010
    ..The identification of the molecules involved in these processes will contribute to the development of more efficient and safer treatment modalities...
  10. pmc In vivo switch to IL-10-secreting T regulatory cells in high dose allergen exposure
    Flurina Meiler
    Swiss Institute of Allergy and Asthma Research, University of Zurich, 7270 Davos, Switzerland
    J Exp Med 205:2887-98. 2008
    ..Thus, rapid switch and expansion of IL-10-producing Tr1 cells and the use of multiple suppressive factors represent essential mechanisms in immune tolerance to a high dose of allergens in nonallergic individuals...
  11. doi request reprint IL-10 suppresses CD2-mediated T cell activation via SHP-1
    Alison Taylor
    Swiss Institute of Allergy and Asthma Research SIAF, Davos, Switzerland
    Mol Immunol 46:622-9. 2009
    ..In conclusion, SHP-1-mediated inhibition of CD2 signaling represents a novel mechanism for direct T cell suppression by IL-10...
  12. pmc Modulation of pathogen-induced CCL20 secretion from HT-29 human intestinal epithelial cells by commensal bacteria
    Shomik Sibartie
    Alimentary Pharmabiotic Centre, University College Cork, National University of Ireland, Cork, Ireland
    BMC Immunol 10:54. 2009
    ..CCL20 and interleukin (IL)-8 secretion and nuclear factor (NF)-kappaB activation were measured using enzyme-linked immunosorbent assays...
  13. doi request reprint Claudin-1 expression in airway smooth muscle exacerbates airway remodeling in asthmatic subjects
    Hiroyuki Fujita
    Swiss Institute of Allergy and Asthma Research, University of Zurich, Davos, Switzerland
    J Allergy Clin Immunol 127:1612-21.e8. 2011
    ..Tight junction (TJ) proteins, which are expressed in endothelial and epithelial cells and affect tissue integrity, might exist in other types of cells and display additional functions in the asthmatic lung...
  14. doi request reprint Histamine receptor 2 modifies dendritic cell responses to microbial ligands
    Remo Frei
    Swiss Institute of Allergy and Asthma Research SIAF, University of Zurich, Davos, Switzerland
    J Allergy Clin Immunol 132:194-204. 2013
    ..The induction of tolerance and protective immunity to microbes is significantly influenced by host- and microbiota-derived metabolites, such as histamine...
  15. doi request reprint Recombinant lactobacilli expressing linoleic acid isomerase can modulate the fatty acid composition of host adipose tissue in mice
    Eva Rosberg-Cody
    Alimentary Pharmabiotic Centre APC, Cork, Ireland
    Microbiology 157:609-15. 2011
    ..These data demonstrate that a single gene (encoding linoleic acid isomerase) expressed in an intestinal microbe can influence the fatty acid composition of host fat...
  16. pmc Commensal-induced regulatory T cells mediate protection against pathogen-stimulated NF-kappaB activation
    Caitlin O'Mahony
    Alimentary Pharmabiotic Centre, University College Cork, Cork, Ireland
    PLoS Pathog 4:e1000112. 2008
    ....
  17. pmc Bifidobacterium infantis 35624 modulates host inflammatory processes beyond the gut
    David Groeger
    Alimentary Health Ltd, Cork, Ireland
    Gut Microbes 4:325-39. 2013
    ..In conclusion, these data show that the immunomodulatory effects of the microbiota in humans are not limited to the mucosal immune system but extend to the systemic immune system. ..
  18. ncbi request reprint Lactobacillus and bifidobacterium in irritable bowel syndrome: symptom responses and relationship to cytokine profiles
    Liam O'Mahony
    Alimentary Pharmabiotic Centre, University College Cork, Cork, Ireland
    Gastroenterology 128:541-51. 2005
    ..The aim of this study was to compare the response of symptoms and cytokine ratios in irritable bowel syndrome (IBS) with ingestion of probiotic preparations containing a lactobacillus or bifidobacterium strain...
  19. pmc Portrait of an immunoregulatory Bifidobacterium
    Patrycja Konieczna
    Swiss Institute of Allergy and Asthma Research, University of Zurich, Davos Platz, Switzerland
    Gut Microbes 3:261-6. 2012
    ..In addition, we discuss the potential DC subset-specific mechanisms, which could contribute to DC(REG) and T(REG) programming by specific gut microbes...
  20. ncbi request reprint Mechanisms of allergen-specific immunotherapy
    Cezmi A Akdis
    Swiss Institute of Allergy and Asthma Research SIAF, Davos, Switzerland
    Chem Immunol Allergy 91:195-203. 2006
    ..By the application of the recent knowledge in mechanisms of allergen-SIT, more rational and safer approaches are awaiting in the future for the prevention and cure of allergic diseases...
  21. doi request reprint Mycobacterium avium subsp. Paratuberculosis (MAP) as a modifying factor in Crohn's disease
    Shomik Sibartie
    Alimentary Pharmabiotic Centre, University College Cork, National University of Ireland, Cork, Ireland
    Inflamm Bowel Dis 16:296-304. 2010
    ..Our aim was to examine the influence of MAP on T-cell proliferation and cytokine responses in patients with inflammatory bowel disease (IBD)...
  22. pmc Transcription factors RUNX1 and RUNX3 in the induction and suppressive function of Foxp3+ inducible regulatory T cells
    Sven Klunker
    Swiss Institute of Allergy and Asthma Research Davos, University of Zurich, CH 7270 Davos Platz, Switzerland
    J Exp Med 206:2701-15. 2009
    ..Furthermore, FOXP3 and RUNX3 were colocalized in human tonsil T reg cells. These data demonstrate Runx transcription factors as a molecular link in TGF-beta-induced Foxp3 expression in iT reg cell differentiation and function...
  23. doi request reprint Mucosal cytokine imbalance in irritable bowel syndrome
    John Macsharry
    Alimentary Health Ltd, Cork, Ireland
    Scand J Gastroenterol 43:1467-76. 2008
    ..To systematically examine mucosal biopsies for differences in cytokine gene expression and protein secretion...
  24. doi request reprint Regulatory effects of histamine and histamine receptor expression in human allergic immune responses
    Cezmi A Akdis
    Swiss Institute of Allergy and Asthma Research SIAF, Davos, Switzerland
    Chem Immunol Allergy 94:67-82. 2008
    ..In addition, differences in affinities of these receptors for histamine are highly decisive for the biological effects of histamine and drugs that target histamine receptors...
  25. doi request reprint Increased activation-induced cell death of high IFN-gamma-producing T(H)1 cells as a mechanism of T(H)2 predominance in atopic diseases
    Tunc Akkoc
    Swiss Institute of Allergy and Asthma Research, Davos, Switzerland
    J Allergy Clin Immunol 121:652-658.e1. 2008
    ..Increased activation and massive infiltration of T cells in the dermis without any evidence for the expansion of their numbers in peripheral blood characterize atopic dermatitis...
  26. doi request reprint Mechanisms and treatment of allergic disease in the big picture of regulatory T cells
    Cezmi A Akdis
    Swiss Institute of Allergy and Asthma Research, University of Zurich, Davos, Switzerland
    J Allergy Clin Immunol 123:735-46; quiz 747-8. 2009
    ..Current strategies for drug development and allergen-specific immunotherapy exploit these observations, with the potential for preventive therapies and cure for allergic diseases...
  27. ncbi request reprint TH17 cells in the big picture of immunology
    Carsten B Schmidt-Weber
    Swiss Institute of Allergy and Asthma Research, Switzerland
    J Allergy Clin Immunol 120:247-54. 2007
    ..This review summarizes the recent developments on T(H) cell subsets and integrates these findings into existing concepts of immunopathologic mechanisms...
  28. doi request reprint Therapeutic manipulation of immune tolerance in allergic disease
    Mubeccel Akdis
    Swiss Institute of Allergy and Asthma Research, University of Zurich, Obere Strasse 22, Davos Platz, Switzerland
    Nat Rev Drug Discov 8:645-60. 2009
    ..This Review highlights current knowledge of immunomodulatory therapies for the manipulation of immune tolerance and highlights recent approaches to improve allergen-specific immunotherapy for the treatment of allergic diseases...
  29. ncbi request reprint Apoptosis and loss of adhesion of bronchial epithelial cells in asthma
    Axel Trautmann
    Swiss Institute of Allergy and Asthma Research SIAF, Davos, Switzerland
    Int Arch Allergy Immunol 138:142-50. 2005
    ..Since EC shedding is a histologic hallmark of asthma, the intercellular junction of EC may be a target of pro-inflammatory cytokines...
  30. ncbi request reprint A major allergen gene-fusion protein for potential usage in allergen-specific immunotherapy
    Fatimah Kussebi
    Swiss Institute of Allergy and Asthma Research, Davos, Switzerland
    J Allergy Clin Immunol 115:323-9. 2005
    ..Differences between epitopes of IgE that recognize the 3-dimensional structure of allergens and T cells that recognize linear amino acid sequences provide a suitable tool for novel vaccine development for specific immunotherapy...
  31. doi request reprint IL-32 is expressed by human primary keratinocytes and modulates keratinocyte apoptosis in atopic dermatitis
    Norbert Meyer
    Swiss Institute of Allergy and Asthma Research SIAF, University of Zurich, Davos, Switzerland High altitude Clinic of Davos, Davos Wolfgang, Switzerland
    J Allergy Clin Immunol 125:858-865.e10. 2010
    ..IL-32 is a proinflammatory cytokine that is involved in the inflammatory processes of rheumatoid arthritis, chronic obstructive pulmonary disease, and Crohn disease. Recently, it was shown that upregulation of IL-32 induces apoptosis...
  32. pmc The Surface-Associated Exopolysaccharide of Bifidobacterium longum 35624 Plays an Essential Role in Dampening Host Proinflammatory Responses and Repressing Local TH17 Responses
    Elisa Schiavi
    Swiss Institute of Allergy and Asthma Research SIAF, University of Zurich, Davos, Switzerland
    Appl Environ Microbiol 82:7185-7196. 2016
    ..longum 35624 plays an essential role in dampening proinflammatory host responses to the strain and that loss of exopolysaccharide production results in the induction of local TH17 responses...
  33. doi request reprint Irritable bowel syndrome-type symptoms in patients with inflammatory bowel disease: a real association or reflection of occult inflammation?
    John Keohane
    Department of Medicine, Alimentary Pharmabiotic Centre, University College Cork, National University of Ireland, Cork, Ireland
    Am J Gastroenterol 105:1788, 1789-94; quiz 1795. 2010
    ....
  34. doi request reprint Metabolic activity of the enteric microbiota influences the fatty acid composition of murine and porcine liver and adipose tissues
    Rebecca Wall
    Alimentary Pharmabiotic Centre, Cork, Ireland
    Am J Clin Nutr 89:1393-401. 2009
    ..Recent reports suggest that the metabolic activity of the gut microbiota may contribute to the pathogenesis of obesity and hepatic steatosis...
  35. ncbi request reprint IL-10 inhibits CD28 and ICOS costimulations of T cells via src homology 2 domain-containing protein tyrosine phosphatase 1
    Alison Taylor
    Swiss Institute of Allergy and Asthma Research, Davos, Switzerland
    J Allergy Clin Immunol 120:76-83. 2007
    ..Specific T-cell activation requires T-cell receptor stimulation and the generation of costimulatory signals. Major costimulatory signals are delivered to T cells by the interaction of CD28 and inducible costimulator (ICOS)...
  36. doi request reprint Technical Advance: Function and efficacy of an {alpha}4-integrin antagonist using bioluminescence imaging to detect leukocyte trafficking in murine experimental colitis
    Carola T Murphy
    Alimentary Pharmabiotic Centre, University College Cork, National University of Ireland, Cork, Ireland
    J Leukoc Biol 88:1271-8. 2010
    ..Furthermore, in vivo bioluminescence imaging is a valuable strategy for preclinical evaluation of potential therapeutics that target leukocyte trafficking in inflammatory diseases...
  37. doi request reprint A molecular analysis of fecal and mucosal bacterial communities in irritable bowel syndrome
    Caroline Codling
    Department of Medicine, Alimentary Pharmabiotic Centre, Cork University Hospital, Cork, Ireland
    Dig Dis Sci 55:392-7. 2010
    ....
  38. ncbi request reprint T regulatory cells in allergy
    Mubeccel Akdis
    Swiss Institute of Allergy and Asthma Research SIAF, Davos, Switzerland
    Chem Immunol Allergy 91:159-73. 2006
    ..It is associated with regulation of antibody isotypes and effector cells to the direction of a healthy immune response and opens a window for novel therapies of allergic diseases...
  39. doi request reprint Immune tolerance in allergy
    Mubeccel Akdis
    Swiss Institute of Allergy and Asthma Research SIAF, University of Zurich, Obere Strasse 22, CH 7270 Davos Platz, Switzerland
    Curr Opin Immunol 21:700-7. 2009
    ..This review focuses on current knowledge of immune tolerance to allergens in healthy immune response to allergens and allergen-SIT...
  40. doi request reprint Interleukins (from IL-1 to IL-38), interferons, transforming growth factor β, and TNF-α: Receptors, functions, and roles in diseases
    Mubeccel Akdis
    Swiss Institute of Allergy and Asthma Research SIAF, University of Zurich, Davos, Switzerland Electronic address
    J Allergy Clin Immunol 138:984-1010. 2016
    ....
  41. pmc Human dendritic cell DC-SIGN and TLR-2 mediate complementary immune regulatory activities in response to Lactobacillus rhamnosus JB-1
    Patrycja Konieczna
    Swiss Institute of Allergy and Asthma Research, University of Zurich, Davos, Switzerland
    PLoS ONE 10:e0120261. 2015
    ..Thus, inhibition or delay of intracellular processing may be a novel strategy by which certain commensals may avoid the induction of proinflammatory responses. ..
  42. pmc Bifidobacterium infantis 35624 protects against salmonella-induced reductions in digestive enzyme activity in mice by attenuation of the host inflammatory response
    Erin L Symonds
    Alimentary Pharmabiotic Centre, National University Ireland, Cork, Ireland
    Clin Transl Gastroenterol 3:e15. 2012
    ....
  43. ncbi request reprint Histamine regulation of innate and adaptive immunity
    Ruth Ferstl
    Swiss Institute of Allergy and Asthma Research, University of Zurich, Davos, Switzerland
    Front Biosci (Landmark Ed) 17:40-53. 2012
    ..In this review, we discuss histamine receptor expression and differential activation of cells within both the innate and adaptive immune response and the signal transduction mechanisms which influence their activity...
  44. doi request reprint Small intestinal bacterial overgrowth in nonalcoholic steatohepatitis: association with toll-like receptor 4 expression and plasma levels of interleukin 8
    Ahmed Abu Shanab
    Alimentary Pharmabiotic Centre, Department of Medicine, University College Cork, National University of Ireland, Cork, Ireland
    Dig Dis Sci 56:1524-34. 2011
    ..Liver injury and fibrosis could be related to exposure to bacterial products of intestinal origin and, most notably, endotoxin, including lipopolysaccharide (LPS)...
  45. ncbi request reprint Mechanisms of allergen-specific immunotherapy
    Mubeccel Akdis
    Swiss Institute of Allergy and Asthma Research, Davos, Switzerland
    J Allergy Clin Immunol 119:780-91. 2007
    ..Current understanding of mechanisms of allergen-SIT, particularly the role of Treg cells in peripheral tolerance, may enable novel treatment strategies...
  46. ncbi request reprint T regulatory cells in allergy: novel concepts in the pathogenesis, prevention, and treatment of allergic diseases
    Mubeccel Akdis
    Swiss Institute of Allergy and Asthma Research SIAF, Davos, Switzerland
    J Allergy Clin Immunol 116:961-8; quiz 969. 2005
    ..Current strategies for drug development and allergen-specific immunotherapy exploit these observations with the potential to provide cure for allergic diseases...
  47. doi request reprint The cellular orchestra in skin allergy; are differences to lung and nose relevant?
    Mubeccel Akdis
    2Swiss Institute of Allergy and Asthma Research SIAF, Davos, Switzerland
    Curr Opin Allergy Clin Immunol 10:443-51. 2010
    ....
  48. doi request reprint Prebiotics, probiotics, synbiotics, and the immune system: experimental data and clinical evidence
    Remo Frei
    aSwiss Institute of Allergy and Asthma Research, University of Zurich bChristine Kühne Center for Allergy Research and Education CK CARE, Davos, Switzerland
    Curr Opin Gastroenterol 31:153-8. 2015
    ..Certain probiotics, prebiotics, and synbiotics are able to influence immune responses. In this review, we highlight the recent publications (within the last 2 years) that have substantially progressed this field...
  49. doi request reprint Interleukins, from 1 to 37, and interferon-γ: receptors, functions, and roles in diseases
    Mubeccel Akdis
    Swiss Institute of Allergy and Asthma Research, University of Zurich, Davos, Switzerland
    J Allergy Clin Immunol 127:701-21.e1-70. 2011
    ..We discuss their signaling pathways, cellular sources, targets, roles in immune regulation and cellular networks, roles in allergy and asthma, and roles in defense against infections...
  50. doi request reprint Mechanisms of allergen-specific immunotherapy
    Cezmi A Akdis
    Swiss Institute of Allergy and Asthma Research SIAF, University of Zurich, Davos, Switzerland
    J Allergy Clin Immunol 127:18-27; quiz 28-9. 2011
    ..New strategies for immune intervention will likely include targeting of the molecular mechanisms of allergen tolerance and reciprocal regulation of effector and Treg cell subsets...
  51. ncbi request reprint A second step of chemotaxis after transendothelial migration: keratinocytes undergoing apoptosis release IFN-gamma-inducible protein 10, monokine induced by IFN-gamma, and IFN-gamma-inducible alpha-chemoattractant for T cell chemotaxis toward epidermis in
    Sven Klunker
    Swiss Institute of Allergy and Asthma Research, Davos, Switzerland
    J Immunol 171:1078-84. 2003
    ..Keratinocytes undergoing apoptosis in acute eczematous lesions release chemokines that attract more T cells toward the epidermis, which may further augment the inflammation and keratinocyte apoptosis...
  52. pmc Role of Regulatory Cells in Oral Tolerance
    Marcin Wawrzyniak
    Swiss Institute of Allergy and Asthma Research SIAF, University of Zurich, Davos, Switzerland
    Allergy Asthma Immunol Res 9:107-115. 2017
    ....
  53. doi request reprint Regulation of the immune response and inflammation by histamine and histamine receptors
    Liam O'Mahony
    Swiss Institute of Allergy and Asthma Research SIAF, University of Zurich, Davos, Switzerland
    J Allergy Clin Immunol 128:1153-62. 2011
    ....
  54. ncbi request reprint IL-10 and TGF-beta cooperate in the regulatory T cell response to mucosal allergens in normal immunity and specific immunotherapy
    Marek Jutel
    Swiss Institute of Allergy and Asthma Research SIAF, Davos, Switzerland
    Eur J Immunol 33:1205-14. 2003
    ..Together, these results demonstrate a deviation towards a regulatory/suppressor T cell response during SIT and in normal immunity as a key event for the healthy immune response to mucosal antigens...
  55. ncbi request reprint Immune regulation by histamine
    Marek Jutel
    Swiss Institute of Allergy and Asthma Research, Obere Strasse 22, CH 7270 Davos, Switzerland
    Curr Opin Immunol 14:735-40. 2002
    ..Apparently, diverse effects of histamine on immune regulation are because of differential expression of four types of histamine receptors and their distinct intracellular signals...