Affiliation: Kantonsspital Liestal
- [Hereditary breast and ovarian cancer - indications for genetic testing, counseling and options for mutation carriers]Nicole Bürki
Frauenklinik, Kantonsspital Liestal
Ther Umsch 67:359-66. 2010..Each of the three management options 'intensified cancer screening', 'chemoprevention' and 'prophylactic surgery' is discussed thoroughly. Recommended cancer screening in male mutation carriers are mentioned as well...
- Levels of plasma circulating cell free nuclear and mitochondrial DNA as potential biomarkers for breast tumorsCorina Kohler
Laboratory for Prenatal Medicine and Gynecologic Oncology, Women s Hospital Department of Biomedicine, University of Basel, Switzerland
Mol Cancer 8:105. 2009..In this connection, circulating cell-free DNA (ccf DNA) seems to be a promising candidate. Altered levels of ccf nuclear DNA (nDNA) and mitochondrial DNA (mtDNA) have been found in several cancer types and might have a diagnostic value...
- Evidence for breast cancer as an integral part of Lynch syndromeNicole Buerki
Department of Obstetrics and Gynecology, Cantonal Hospital of Liestal, Liestal, Switzerland
Genes Chromosomes Cancer 51:83-91. 2012..7%) of 22 breast cancer specimens from MLH1/MSH2 mutation carriers. These findings, thus, provide strong molecular evidence for a pivotal role of MMR deficiency in breast cancer development in Lynch syndrome...