Gongda Xue

Summary

Affiliation: Friedrich Miescher Institute
Country: Switzerland

Publications

  1. doi Akt/PKB-mediated phosphorylation of Twist1 promotes tumor metastasis via mediating cross-talk between PI3K/Akt and TGF-β signaling axes
    Gongda Xue
    Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland
    Cancer Discov 2:248-59. 2012
  2. doi PKB/Akt-dependent regulation of cell motility
    Gongda Xue
    Friedrich Miescher Institute for Biomedical Research, Maulbeerstrasse 66, CH 4058, Basel, Switzerland
    J Natl Cancer Inst 105:393-404. 2013
  3. doi Phosphorylation of basic helix-loop-helix transcription factor Twist in development and disease
    Gongda Xue
    Friedrich Miescher Institute for Biomedical Research, Maulbeerstrasse 66, CH 4058 Basel, Switzerland
    Biochem Soc Trans 40:90-3. 2012
  4. doi Protein kinase B (PKB/Akt), a key mediator of the PI3K signaling pathway
    Elisabeth Fayard
    Friedrich Miescher Institute for Biomedical Research, Maulbeerstrasse 66, 4058, Basel, Switzerland
    Curr Top Microbiol Immunol 346:31-56. 2010
  5. doi The kinases NDR1/2 act downstream of the Hippo homolog MST1 to mediate both egress of thymocytes from the thymus and lymphocyte motility
    Fengyuan Tang
    Friedrich Miescher Institute for Biomedical Research, 4058 Basel, Switzerland Department of Biomedicine, University of Basel, 4058 Basel, Switzerland
    Sci Signal 8:ra100. 2015

Collaborators

Detail Information

Publications5

  1. doi Akt/PKB-mediated phosphorylation of Twist1 promotes tumor metastasis via mediating cross-talk between PI3K/Akt and TGF-β signaling axes
    Gongda Xue
    Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland
    Cancer Discov 2:248-59. 2012
    ..Our results describe a novel signaling event linking PI3K/Akt hyperactivation in tumor cells to direct regulation of Twist1 activation and tumor metastasis...
  2. doi PKB/Akt-dependent regulation of cell motility
    Gongda Xue
    Friedrich Miescher Institute for Biomedical Research, Maulbeerstrasse 66, CH 4058, Basel, Switzerland
    J Natl Cancer Inst 105:393-404. 2013
    ..We focus in particular on its direct influence on cell migration and invasion, epithelial-mesenchymal transition, and cancer metastasis...
  3. doi Phosphorylation of basic helix-loop-helix transcription factor Twist in development and disease
    Gongda Xue
    Friedrich Miescher Institute for Biomedical Research, Maulbeerstrasse 66, CH 4058 Basel, Switzerland
    Biochem Soc Trans 40:90-3. 2012
    ....
  4. doi Protein kinase B (PKB/Akt), a key mediator of the PI3K signaling pathway
    Elisabeth Fayard
    Friedrich Miescher Institute for Biomedical Research, Maulbeerstrasse 66, 4058, Basel, Switzerland
    Curr Top Microbiol Immunol 346:31-56. 2010
    ....
  5. doi The kinases NDR1/2 act downstream of the Hippo homolog MST1 to mediate both egress of thymocytes from the thymus and lymphocyte motility
    Fengyuan Tang
    Friedrich Miescher Institute for Biomedical Research, 4058 Basel, Switzerland Department of Biomedicine, University of Basel, 4058 Basel, Switzerland
    Sci Signal 8:ra100. 2015
    ..Together, our findings indicate that the kinases NDR1 and NDR2 function as downstream effectors of MST1 to mediate thymocyte egress and T cell migration. ..