Armin von Gunten

Summary

Affiliation: Centre Hospitalier Universitaire Vaudois
Country: Switzerland

Publications

  1. ncbi request reprint Environmental reduplicative paramnesia in a case of atypical Alzheimer's disease
    Armin von Gunten
    Service Universitaire de Psychiatrie de l Age Avancé, Centre Hospitalier Universitaire Vandois, Lausanne, Switzerland
    Neurocase 11:216-26. 2005
  2. ncbi request reprint Cognitive and demographic determinants of dementia in depressed patients with subjective memory complaints
    Armin von Gunten
    Service of Old Age Psychiatry, Department of Psychiatry, CHUV, Lausanne, Switzerland
    Eur Neurol 54:154-8. 2005
  3. ncbi request reprint Morphological substrates of cognitive decline in nonagenarians and centenarians: a new paradigm?
    Anouk Imhof
    Department of Psychiatry, HUG, Belle Idee, University of Geneva School of Medicine, Geneva, Switzerland
    J Neurol Sci 257:72-9. 2007
  4. ncbi request reprint Cognitive impact of neuronal pathology in the entorhinal cortex and CA1 field in Alzheimer's disease
    Armin von Gunten
    Service of Old Age Psychiatry, University of Lausanne School of Medicine, 1008 Prilly, Lausanne, Switzerland
    Neurobiol Aging 27:270-7. 2006
  5. doi request reprint Pathological substrates of cognitive decline in Alzheimer's disease
    Panteleimon Giannakopoulos
    Department of Psychiatry, University of Geneva School of Medicine, Chene Bourg, Geneva, Switzerland
    Front Neurol Neurosci 24:20-9. 2009
  6. pmc Population pharmacokinetic approach to evaluate the effect of CYP2D6, CYP3A, ABCB1, POR and NR1I2 genotypes on donepezil clearance
    Muriel Noetzli
    Unit of Pharmacogenetics and Clinical Psychopharmacology, Centre for Psychiatric Neuroscience, Department of Psychiatry, Hospital of Cery, Lausanne University Hospital, Prilly, Switzerland
    Br J Clin Pharmacol 78:135-44. 2014
  7. doi request reprint Relationship of CYP2D6, CYP3A, POR, and ABCB1 genotypes with galantamine plasma concentrations
    Muriel Noetzli
    Unit of Pharmacogenetics and Clinical Psychopharmacology, Centre for Psychiatric Neuroscience, Department of Psychiatry, University Hospital Lausanne, Prilly Lausanne, Switzerland
    Ther Drug Monit 35:270-5. 2013
  8. ncbi request reprint Assessing the cognitive impact of Alzheimer disease pathology and vascular burden in the aging brain: the Geneva experience
    Panteleimon Giannakopoulos
    Division of Geriatric Psychiatry, Department of Psychiatry, University of Geneva School of Medicine, 1225 Chene Bourg, Geneva, Switzerland
    Acta Neuropathol 113:1-12. 2007
  9. ncbi request reprint Prediction of early weight gain during psychotropic treatment using a combinatorial model with clinical and genetic markers
    Frederik Vandenberghe
    aUnit of Pharmacogenetics and Clinical Psychopharmacology, Department of Psychiatry, Centre for Psychiatric Neuroscience bDepartment of Psychiatry, Center for Psychiatric Epidemiology and Psychopathology cDepartment of Psychiatry, Service of Old Age Psychiatry dDepartment of Psychiatry, Service of General Psychiatry, Lausanne University Hospital, Hospital of Cery, Prilly eDepartment of Pharmaceutical Sciences, School of Pharmacy, University of Geneva, University of Lausanne, Geneva, Switzerland
    Pharmacogenet Genomics 26:547-557. 2016
  10. pmc Association between frailty and delirium in older adult patients discharged from hospital
    Henk Verloo
    Department Nursing Sciences, University of Applied Sciences, Lausanne, Switzerland
    Clin Interv Aging 11:55-63. 2016

Collaborators

Detail Information

Publications40

  1. ncbi request reprint Environmental reduplicative paramnesia in a case of atypical Alzheimer's disease
    Armin von Gunten
    Service Universitaire de Psychiatrie de l Age Avancé, Centre Hospitalier Universitaire Vandois, Lausanne, Switzerland
    Neurocase 11:216-26. 2005
    ..These findings are compared to those reported in frontal and frontotemporal variants of AD and discussed in the light of current anatomoclinical models for environmental RP...
  2. ncbi request reprint Cognitive and demographic determinants of dementia in depressed patients with subjective memory complaints
    Armin von Gunten
    Service of Old Age Psychiatry, Department of Psychiatry, CHUV, Lausanne, Switzerland
    Eur Neurol 54:154-8. 2005
    ..However, not all such patients have cognitive decline. The aim of this longitudinal study was to identify possible clinical determinants of progressive deterioration in depressed elderly patients with SMC...
  3. ncbi request reprint Morphological substrates of cognitive decline in nonagenarians and centenarians: a new paradigm?
    Anouk Imhof
    Department of Psychiatry, HUG, Belle Idee, University of Geneva School of Medicine, Geneva, Switzerland
    J Neurol Sci 257:72-9. 2007
    ....
  4. ncbi request reprint Cognitive impact of neuronal pathology in the entorhinal cortex and CA1 field in Alzheimer's disease
    Armin von Gunten
    Service of Old Age Psychiatry, University of Lausanne School of Medicine, 1008 Prilly, Lausanne, Switzerland
    Neurobiol Aging 27:270-7. 2006
    ..Moreover, they show that less than 50% of the cognitive variability may be attributable to AD neuronal pathology in these areas...
  5. doi request reprint Pathological substrates of cognitive decline in Alzheimer's disease
    Panteleimon Giannakopoulos
    Department of Psychiatry, University of Geneva School of Medicine, Chene Bourg, Geneva, Switzerland
    Front Neurol Neurosci 24:20-9. 2009
    ..The present review discusses the complex structure/function relationships in brain aging and AD within the theoretical framework of the functional neuropathology of brain aging...
  6. pmc Population pharmacokinetic approach to evaluate the effect of CYP2D6, CYP3A, ABCB1, POR and NR1I2 genotypes on donepezil clearance
    Muriel Noetzli
    Unit of Pharmacogenetics and Clinical Psychopharmacology, Centre for Psychiatric Neuroscience, Department of Psychiatry, Hospital of Cery, Lausanne University Hospital, Prilly, Switzerland
    Br J Clin Pharmacol 78:135-44. 2014
    ..We aimed to evaluate clinical and genetic factors influencing donepezil disposition in a patient population recruited from a naturalistic setting...
  7. doi request reprint Relationship of CYP2D6, CYP3A, POR, and ABCB1 genotypes with galantamine plasma concentrations
    Muriel Noetzli
    Unit of Pharmacogenetics and Clinical Psychopharmacology, Centre for Psychiatric Neuroscience, Department of Psychiatry, University Hospital Lausanne, Prilly Lausanne, Switzerland
    Ther Drug Monit 35:270-5. 2013
    ..We aimed to study the relationship between genetic variants influencing the activity of these enzymes and transporters with galantamine steady state plasma concentrations...
  8. ncbi request reprint Assessing the cognitive impact of Alzheimer disease pathology and vascular burden in the aging brain: the Geneva experience
    Panteleimon Giannakopoulos
    Division of Geriatric Psychiatry, Department of Psychiatry, University of Geneva School of Medicine, 1225 Chene Bourg, Geneva, Switzerland
    Acta Neuropathol 113:1-12. 2007
    ....
  9. ncbi request reprint Prediction of early weight gain during psychotropic treatment using a combinatorial model with clinical and genetic markers
    Frederik Vandenberghe
    aUnit of Pharmacogenetics and Clinical Psychopharmacology, Department of Psychiatry, Centre for Psychiatric Neuroscience bDepartment of Psychiatry, Center for Psychiatric Epidemiology and Psychopathology cDepartment of Psychiatry, Service of Old Age Psychiatry dDepartment of Psychiatry, Service of General Psychiatry, Lausanne University Hospital, Hospital of Cery, Prilly eDepartment of Pharmaceutical Sciences, School of Pharmacy, University of Geneva, University of Lausanne, Geneva, Switzerland
    Pharmacogenet Genomics 26:547-557. 2016
    ..The large interindividual variability of drug-induced WG can be explained in part by genetic and clinical factors...
  10. pmc Association between frailty and delirium in older adult patients discharged from hospital
    Henk Verloo
    Department Nursing Sciences, University of Applied Sciences, Lausanne, Switzerland
    Clin Interv Aging 11:55-63. 2016
    ..This study aimed to explore the relationship between delirium and frailty in older adults discharged from hospitals...
  11. doi request reprint Clock-drawing test performance in the normal elderly and its dependence on age and education
    Armin von Gunten
    Service Universitaire, Departement de Psychiatrie, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland
    Eur Neurol 60:73-8. 2008
    ..The main objective was to assess the relative frequency and types of errors on the clock-drawing test (CDT) in normal elderly subjects, and the dependence of their CDT performance upon their age and education...
  12. doi request reprint Association of genetic risk scores with body mass index in Swiss psychiatric cohorts
    Núria Saigi-Morgui
    aUnit of Pharmacogenetics and Clinical Psychopharmacology, Department of Psychiatry, Centre for Psychiatric Neuroscience bDepartment of Psychiatry, Centre of Psychiatric Epidemiology and Psychopathology cService of Old Age Psychiatry, Department of Psychiatry dService of General Psychiatry, Department of Psychiatry, Lausanne University Hospital, Prilly eDepartment of Mental Health and Psychiatry, University Hospital of Geneva fSchool of Pharmaceutical Sciences, University of Geneva, University of Lausanne, Geneva gInstitute of Social and Preventive Medicine IUMSP, Lausanne University Hospital hSwiss Institute of Bioinformatics, Lausanne, Switzerland
    Pharmacogenet Genomics 26:208-17. 2016
    ....
  13. doi request reprint Behavioral and psychological symptoms and cognitive decline in patients with amnestic MCI and mild AD: a two-year follow-up study
    Cornelia Pocnet
    Institute of Psychology, University of Lausanne, Lausanne, Switzerland
    Int Psychogeriatr 27:1379-89. 2015
    ..Hence, we wondered to what extent specific BPS are associated with cognitive decline in participants with MCI or AD...
  14. pmc Demyelination in mild cognitive impairment suggests progression path to Alzheimer's disease
    Cristian Carmeli
    LREN, Department of Clinical Neurosciences, Centre Hospitalier Universitaire Vaudois CHUV, and University of Lausanne, Lausanne, Switzerland
    PLoS ONE 8:e72759. 2013
    ..In vivo staging of preclinical AD can be developed in terms of WM/GM demyelination. ..
  15. doi request reprint Personality traits and behavioral and psychological symptoms in patients at an early stage of Alzheimer's disease
    Cornelia Pocnet
    Service of Old Age Psychiatry, Department of Psychiatry, Lausanne University Hospital, Prilly Lausanne, Switzerland
    Int J Geriatr Psychiatry 28:276-83. 2013
    ..Focusing on individual personality structure, we explored the relationship between premorbid personality and its changes over 5 years, and BPS in patients at an early stage of AD...
  16. ncbi request reprint Subtle imitation behaviour in convenience samples of normal, demented, and currently depressed elderly subjects
    Armin von Gunten
    Service of Old Age Psychiatry of the Department of Psychiatry CHUV, Lausanne, Switzerland
    Int J Geriatr Psychiatry 22:568-73. 2007
    ..The clinical significance of imitation behaviour (IB) is unclear. The aim of this study was to investigate the prevalence of subtle naïve and obstinate IB in convenience samples of normal elderly, demented, and depressed subjects...
  17. doi request reprint Abnormal sensitivity to negative feedback in late-life depression
    Armin von Gunten
    Service of Old Age Psychiatry, Department of Psychiatry, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Prilly Lausanne, Switzerland
    Psychiatry Clin Neurosci 65:333-40. 2011
    ..The purpose of the present study was to probe sensitivity to potentially misleading negative feedback on cognitive tasks as a possible mechanism of cognitive impairment in elderly patients with mild depression...
  18. ncbi request reprint Personality changes in patients with beginning Alzheimer disease
    Cornelia Pocnet
    Service of Old Age Psychiatry, Department of Psychiatry, Centre Hospitalier Universitaire Vaudois, University of Lausanne, Switzerland
    Can J Psychiatry 56:408-17. 2011
    ..We compared both current personality characteristics using structured interviews as well as current and previous personality traits as assessed by proxies...
  19. ncbi request reprint [Cognitive impairment in elderly patients: what to do in primary care?]
    Florence Brulhart Gremaud
    Departement de Medecine, CHUV, Lausanne
    Rev Med Suisse 9:2029-33. 2013
    ..Unclear situations benefit from an assessment in a memory clinic...
  20. ncbi request reprint Stereologic analysis of hippocampal Alzheimer's disease pathology in the oldest-old: evidence for sparing of the entorhinal cortex and CA1 field
    Armin von Gunten
    Service of Old Age Psychiatry, University of Lausanne School of Medicine, 1008 Prilly, Lausanne, Switzerland
    Exp Neurol 193:198-206. 2005
    ..They also suggest that dementia in extreme aging depends more on the damage of hippocampal subdivisions commonly less affected than on severe NFT formation and neuronal loss in the CA1 field and entorhinal cortex...
  21. doi request reprint An exploratory study on facial emotion recognition capacity in beginning Alzheimer's disease
    Marzanna Wiechetek Ostos
    Consultation de la Mémoire, Departement de Psychiatrie, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland
    Eur Neurol 65:361-7. 2011
    ..It was the aim of this study to investigate facial emotion recognition (FER) in the elderly with cognitive impairment...
  22. doi request reprint Genetics-Based Population Pharmacokinetics and Pharmacodynamics of Risperidone in a Psychiatric Cohort
    Frederik Vandenberghe
    Unit of Pharmacogenetics and Clinical Psychopharmacology, Centre for Psychiatric Neuroscience, Department of Psychiatry, Hospital of Cery, Lausanne University Hospital, 1008, Prilly, Switzerland
    Clin Pharmacokinet 54:1259-72. 2015
    ..High interindividual variability in plasma concentrations of risperidone and its active metabolite, 9-hydroxyrisperidone, may lead to suboptimal drug concentration...
  23. doi request reprint Cognition and psychopathology in nonagenarians and centenarians living in geriatric nursing homes in Switzerland: a focus on anosognosia
    Jean Frédéric Mall
    Service of Old Age Psychiatry, Department of Psychiatry, Centre Hospitalier Universitaire Vaudois CHUV, Prilly Lausanne, Switzerland
    Psychogeriatrics 14:55-62. 2014
    ..Very little is known about psychiatric symptoms and cognitive abilities other than memory in this population. This exploratory study focuses on anosognosia and its relationship with common psychiatric and cognitive symptoms...
  24. doi request reprint A longitudinal study on delirium in nursing homes
    Armin von Gunten
    Service of Old Age Psychiatry, Department of Psychiatry, Lausanne University Hospital, Prilly Lausanne, Switzerland Electronic address
    Am J Geriatr Psychiatry 21:963-72. 2013
    ..To investigate the evolution of delirium of nursing home (NH) residents and their possible predictors...
  25. ncbi request reprint [The differential diagnosis of cognitive disorders in general practice: dementia and delirium]
    Armin von Gunten
    Service Universitaire de Psychiatrie de l Age Avancé, Departement de Psychiatrie, CHUV, Prilly
    Rev Med Suisse 3:389-90, 392, 394-5. 2007
    ....
  26. ncbi request reprint [Preventive approaches to dementia]
    Stephan Eyer
    Department de Medecine, CHUV, Lausanne
    Rev Med Suisse 6:2141-5. 2010
    ..Cognitive training and physical activity seem promising. This paper describes recent studies that assessed the benefits of preventive strategies in the domain of dementia, especially in Alzheimer's disease...
  27. pmc Development and validation of clinical profiles of patients hospitalized due to behavioral and psychological symptoms of dementia
    Claudia Ortoleva Bucher
    Institute of Higher Education and Research in Healthcare IUFRS, Faculty of Biology and Medicine, University of Lausanne and Lausanne University Hospital, Route de la Corniche 10, 1010, Lausanne, Switzerland
    BMC Psychiatry 16:261. 2016
    ..The present study aims to partition patients hospitalized due to behavioral and psychological symptoms of dementia into profiles based on a global evaluation of mental health using cluster analysis...
  28. doi request reprint Life events, salivary cortisol, and cognitive performance in nondemented subjects: a population-based study
    Sami Ouanes
    Department of Psychiatry, University Hospital of Lausanne, Lausanne, Switzerland
    Neurobiol Aging 51:1-8. 2016
    ..The association of higher cortisol levels with poorer cognition might be not a mere reflection of stressful events but rather explained by other factors, yet to be elucidated...
  29. doi request reprint Importance of early weight changes to predict long-term weight gain during psychotropic drug treatment
    Frederik Vandenberghe
    Unit of Pharmacogenetics and Clinical Psychopharmacology, Centre for Psychiatric Neuroscience, Department of Psychiatry, Lausanne University Hospital, Hospital of Cery, Prilly, Switzerland
    J Clin Psychiatry 76:e1417-23. 2015
    ..The authors aimed to determine the potential predictive power of an early weight gain after the introduction of weight gain-inducing psychotropic drugs on long-term weight gain...
  30. doi request reprint Subjective cognitive decline in patients with mild cognitive impairment and healthy older adults: association with personality traits
    Joseph Studer
    Service of Old Age Psychiatry, Department of Psychiatry, Lausanne University Hospital, Lausanne, Switzerland
    Geriatr Gerontol Int 14:589-95. 2014
    ....
  31. doi request reprint Population pharmacokinetic study of memantine: effects of clinical and genetic factors
    Muriel Noetzli
    Unit of Pharmacogenetics and Clinical Psychopharmacology, Centre for Psychiatric Neuroscience, Department of Psychiatry, Hospital of Cery, University Hospital Lausanne, 1008 Prilly Lausanne, Switzerland
    Clin Pharmacokinet 52:211-23. 2013
    ..Considerable inter-individual variability in plasma concentrations has been reported. We aimed to investigate clinical and genetic factors influencing memantine disposition...
  32. doi request reprint Delirium upon admission to Swiss nursing homes: a cross-sectional study
    Armin von Gunten
    Service of Old Age Psychiatry, Department of Psychiatry, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Prilly, Switzerland
    Swiss Med Wkly 140:376-81. 2010
    ..We wished to investigate the prevalence of delirium in patients upon admission to nursing homes and whether or not the previous place of residence predicts delirium...
  33. doi request reprint The impact of personality characteristics on the clinical expression in neurodegenerative disorders--a review
    Armin von Gunten
    Consultation de la Mémoire, Service Universitaire de Psychiatrie de l Age Avancé, Departement de Psychiatrie, Centre Hospitalier Universitaire Vaudois and University of Lausanne, 1005 Lausanne, Switzerland
    Brain Res Bull 80:179-91. 2009
    ....
  34. ncbi request reprint Hippocampal volume and subjective memory impairment in depressed patients
    Armin von Gunten
    Service universitaire de psychogériatrie, Route du Mont, 1008 Prilly, Lausanne, Switzerland
    Eur Psychiatry 19:438-40. 2004
    ....
  35. ncbi request reprint Stereologic analysis of microvascular morphology in the elderly: Alzheimer disease pathology and cognitive status
    Constantin Bouras
    Departments of Psychiatry, HUG Belle Idée, University of Geneva School of Medicine, Switzerland
    J Neuropathol Exp Neurol 65:235-44. 2006
    ....
  36. ncbi request reprint Neural substrates of cognitive and behavioral deficits in atypical Alzheimer's disease
    Armin von Gunten
    Division of Old Age Psychiatry, Department of Psychiatry CHUV, Prilly Lausanne, Switzerland
    Brain Res Rev 51:176-211. 2006
    ....
  37. doi request reprint Vocally disruptive behavior in the elderly: a systematic review
    Armin von Gunten
    Service Universitaire de Psychiatrie de l Age Avancé SUPAA, Prilly, Switzerland
    Int Psychogeriatr 20:653-72. 2008
    ..It may occur in as many as 40% of nursing home residents. This study is a review of the existing literature on this condition...
  38. ncbi request reprint [Treatment of Alzheimer's disease: clinicians's lecture]
    Sabine Joray
    Rev Med Suisse 2:307. 2006
  39. ncbi request reprint Environmental reduplicative paramnesia in a case of atypical Alzheimer's disease
    Armin von Gunten
    J Neurol 251:750-2. 2004
  40. ncbi request reprint [Dementia syndrome of affective and psychotic origin in the elderly: illustration with clinical cases]
    Armin von Gunten
    Hôpital psychogériatrique, Service universitaire de psychogériatrie, rte du Mont, 1008 Prilly
    Rev Med Suisse Romande 122:85-9. 2002
    ....