A Bouchon

Summary

Affiliation: Basel Institute for Immunology
Country: Switzerland

Publications

  1. ncbi request reprint Critical role for mitochondria in B cell receptor-mediated apoptosis
    A Bouchon
    Tumor Immunology Program, German Cancer Research Center DKFZ, Heidelberg, Germany
    Eur J Immunol 30:69-77. 2000
  2. ncbi request reprint Tumor necrosis factor-related apoptosis-inducing ligand retains its apoptosis-inducing capacity on Bcl-2- or Bcl-xL-overexpressing chemotherapy-resistant tumor cells
    H Walczak
    Tumor Immunology Program, German Cancer Research Center, Heidelberg, Germany
    Cancer Res 60:3051-7. 2000

Detail Information

Publications2

  1. ncbi request reprint Critical role for mitochondria in B cell receptor-mediated apoptosis
    A Bouchon
    Tumor Immunology Program, German Cancer Research Center DKFZ, Heidelberg, Germany
    Eur J Immunol 30:69-77. 2000
    ..Thus, BCR-mediated apoptosis is initiated by the caspase-independent induction of mitochondrial PT resulting in release of cytochrome c and subsequent activation of caspase-9, downstream caspases and apoptosis...
  2. ncbi request reprint Tumor necrosis factor-related apoptosis-inducing ligand retains its apoptosis-inducing capacity on Bcl-2- or Bcl-xL-overexpressing chemotherapy-resistant tumor cells
    H Walczak
    Tumor Immunology Program, German Cancer Research Center, Heidelberg, Germany
    Cancer Res 60:3051-7. 2000
    ..Thus, TRAIL may still kill tumors that have acquired resistance to chemotherapeutic drugs by overexpression of Bcl-2 or Bcl-xL. These data will influence future treatment strategies involving TRAIL...