Maria Planck

Summary

Affiliation: University Hospital
Country: Sweden

Publications

  1. ncbi hMLH1, hMSH2 and hMSH6 mutations in hereditary non-polyposis colorectal cancer families from southern Sweden
    M Planck
    Department of Oncology, University Hospital, Lund, Sweden
    Int J Cancer 83:197-202. 1999
  2. ncbi Somatic frameshift alterations in mononucleotide repeat-containing genes in different tumor types from an HNPCC family with germline MSH2 mutation
    M Planck
    Department of Oncology, University Hospital, Lund, Sweden
    Genes Chromosomes Cancer 29:33-9. 2000
  3. ncbi Cytogenetic aberrations and heterogeneity of mutations in repeat-containing genes in a colon carcinoma from a patient with hereditary nonpolyposis colorectal cancer
    Maria Planck
    Department of Oncology, University Hospital, 221 85 Lund, Sweden
    Cancer Genet Cytogenet 134:46-54. 2002
  4. ncbi High frequency of microsatellite instability and loss of mismatch-repair protein expression in patients with double primary tumors of the endometrium and colorectum
    Maria Planck
    Department of Oncology, The Jubileum Institution, University Hospital, Lund, Sweden
    Cancer 94:2502-10. 2002
  5. ncbi Microsatellite instability and expression of MLH1 and MSH2 in carcinomas of the small intestine
    Maria Planck
    Department of Oncology, University Hospital, Lund, Sweden
    Cancer 97:1551-7. 2003
  6. doi Detecting EGFR alterations in clinical specimens-pitfalls and necessities
    Sofi Isaksson
    Department of Clinical Sciences, Division of Oncology, Lund University, Medicon Village, SE 223 81, Lund, Sweden
    Virchows Arch 463:755-64. 2013
  7. doi Genome-wide DNA methylation analysis of lung carcinoma reveals one neuroendocrine and four adenocarcinoma epitypes associated with patient outcome
    Anna Karlsson
    Division of Oncology and Pathology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden
    Clin Cancer Res 20:6127-40. 2014
  8. pmc Genomic and transcriptional alterations in lung adenocarcinoma in relation to EGFR and KRAS mutation status
    Maria Planck
    Department of Oncology, Clinical Sciences, Lund University and Skåne University Hospital, Medicon Village, Lund, Sweden
    PLoS ONE 8:e78614. 2013
  9. pmc Phenotypic heterogeneity in hereditary non-polyposis colorectal cancer: identical germline mutations associated with variable tumour morphology and immunohistochemical expression
    Britta Halvarsson
    Department of Pathology, Lund University Hospital, Lund, Sweden
    J Clin Pathol 60:781-6. 2007
  10. doi Histological specificity of alterations and expression of KIT and KITLG in non-small cell lung carcinoma
    Annette Salomonsson
    Division of Oncology, Department of Clinical Sciences, Lund University and Skåne University Hospital, Lund, Sweden
    Genes Chromosomes Cancer 52:1088-96. 2013

Detail Information

Publications16

  1. ncbi hMLH1, hMSH2 and hMSH6 mutations in hereditary non-polyposis colorectal cancer families from southern Sweden
    M Planck
    Department of Oncology, University Hospital, Lund, Sweden
    Int J Cancer 83:197-202. 1999
    ..Our results present novel germ-line DNA-repair gene mutations, one of these in hMSH6, and demonstrate the diversified mutation spectrum in Sweden, where no founder mutation has so far been identified...
  2. ncbi Somatic frameshift alterations in mononucleotide repeat-containing genes in different tumor types from an HNPCC family with germline MSH2 mutation
    M Planck
    Department of Oncology, University Hospital, Lund, Sweden
    Genes Chromosomes Cancer 29:33-9. 2000
    ..We suggest, however, that the accumulation of somatic frameshifts, rather than the specific loci in which these occur, drives the development of the tumorigenic phenotype in HNPCC...
  3. ncbi Cytogenetic aberrations and heterogeneity of mutations in repeat-containing genes in a colon carcinoma from a patient with hereditary nonpolyposis colorectal cancer
    Maria Planck
    Department of Oncology, University Hospital, 221 85 Lund, Sweden
    Cancer Genet Cytogenet 134:46-54. 2002
    ..Furthermore, the observed intratumoral heterogeneity of mutations in coding repeats implies these changes occur late in tumorigenesis and, thus, probably play a role in tumor progression rather than initiation...
  4. ncbi High frequency of microsatellite instability and loss of mismatch-repair protein expression in patients with double primary tumors of the endometrium and colorectum
    Maria Planck
    Department of Oncology, The Jubileum Institution, University Hospital, Lund, Sweden
    Cancer 94:2502-10. 2002
    ..The objective of this study was to estimate the proportion of double primary tumors of the endometrium and colorectum that displays tumor characteristics suggestive of MMR deficiency...
  5. ncbi Microsatellite instability and expression of MLH1 and MSH2 in carcinomas of the small intestine
    Maria Planck
    Department of Oncology, University Hospital, Lund, Sweden
    Cancer 97:1551-7. 2003
    ..However, a subset of several sporadic tumor types, including about 15% of colon cancers, also evolve through defective MMR...
  6. doi Detecting EGFR alterations in clinical specimens-pitfalls and necessities
    Sofi Isaksson
    Department of Clinical Sciences, Division of Oncology, Lund University, Medicon Village, SE 223 81, Lund, Sweden
    Virchows Arch 463:755-64. 2013
    ....
  7. doi Genome-wide DNA methylation analysis of lung carcinoma reveals one neuroendocrine and four adenocarcinoma epitypes associated with patient outcome
    Anna Karlsson
    Division of Oncology and Pathology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden
    Clin Cancer Res 20:6127-40. 2014
    ..However, whether clinically relevant subgroups based on DNA methylation patterns exist in lung cancer remains unclear...
  8. pmc Genomic and transcriptional alterations in lung adenocarcinoma in relation to EGFR and KRAS mutation status
    Maria Planck
    Department of Oncology, Clinical Sciences, Lund University and Skåne University Hospital, Medicon Village, Lund, Sweden
    PLoS ONE 8:e78614. 2013
    ..Improved knowledge about genomic and transcriptional alterations in and between mutation-defined subgroups may identify genes involved in disease development or progression...
  9. pmc Phenotypic heterogeneity in hereditary non-polyposis colorectal cancer: identical germline mutations associated with variable tumour morphology and immunohistochemical expression
    Britta Halvarsson
    Department of Pathology, Lund University Hospital, Lund, Sweden
    J Clin Pathol 60:781-6. 2007
    ..Colorectal cancer in HNPCC is characterised by poor tumour differentiation, an expanding growth pattern, and a pronounced lymphocytic reaction with tumour-infiltrating lymphocytes...
  10. doi Histological specificity of alterations and expression of KIT and KITLG in non-small cell lung carcinoma
    Annette Salomonsson
    Division of Oncology, Department of Clinical Sciences, Lund University and Skåne University Hospital, Lund, Sweden
    Genes Chromosomes Cancer 52:1088-96. 2013
    ....
  11. doi Lack of supportive evidence for the use of immunohistochemical staining to identify occult regional lymph node metastases in primary lung cancer
    Per Jonsson
    Department of Thoracic Surgery, Lund University and Skåne University Hospital, 221 85, Lund, Sweden
    Virchows Arch 464:429-34. 2014
    ..Moreover, we report several potential pitfalls in the use of broad-spectrum cytokeratin IHC staining for OM detection, for example staining of intra-nodal mesothelial cells...
  12. doi Genomic and transcriptional alterations in lung adenocarcinoma in relation to smoking history
    Anna Karlsson
    Division of Oncology and Pathology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden CREATE Health Strategic Center for Translational Cancer Research, Lund University, Lund, Sweden
    Clin Cancer Res 20:4912-24. 2014
    ..Cigarette smoking is the major pathogenic factor for lung cancer. The precise mechanisms of tobacco-related carcinogenesis and its effect on the genomic and transcriptional landscape in lung cancer are not fully understood...
  13. doi Landscape of somatic allelic imbalances and copy number alterations in human lung carcinoma
    Johan Staaf
    Department of Oncology, Clinical Sciences, Lund University and Skåne University Hospital, Barngatan 2B, Lund, Sweden
    Int J Cancer 132:2020-31. 2013
    ..In summary, these analyses provide a comprehensive overview of the landscape of genomic alterations in lung cancer, highlighting differences but also similarities between subgroups of the disease...
  14. ncbi Familial risk of tumors associated with hereditary non-polyposis colorectal cancer: a Swedish population-based study
    K Ericson
    Dept of Oncology, Lund University Hospital, Lund, Sweden
    Scand J Gastroenterol 39:1259-65. 2004
    ....
  15. ncbi Defective mismatch-repair in patients with multiple primary tumours including colorectal cancer
    K Ericson
    Department of Oncology, University Hospital, 221 85 Lund, Sweden
    Eur J Cancer 39:240-8. 2003
    ..We conclude that the development of multiple primary tumours, including synchronous or metachronous colorectal cancers, is associated with an increased frequency of MSI and loss of immunohistochemical expression of MLH1 and MSH2...
  16. doi Identification of transcriptional subgroups in EGFR-mutated and EGFR/KRAS wild-type lung adenocarcinoma reveals gene signatures associated with patient outcome
    Maria Planck
    Authors Affiliations Department of Oncology, Clinical Sciences, Skåne University Hospital and CREATE Health Strategic Center for Translational Cancer Research, Lund University, Lund, Sweden
    Clin Cancer Res 19:5116-26. 2013
    ..We sought to determine whether transcriptional subgroups of clinical relevance exist within EGFR-mutated, KRAS-mutated, or EGFR and KRAS wild-type (EGFRwt/KRASwt) adenocarcinomas...