Ning Xu

Summary

Affiliation: Lund University
Country: Sweden

Publications

  1. pmc Determination of single-nucleotide polymorphism in the proximal promoter region of apolipoprotein M gene in coronary artery diseases
    Lu Zheng
    Comprehensive Laboratory, The Third Affiliated Hospital, Suzhou University, Changzhou China
    Int J Gen Med 2:177-82. 2009
  2. pmc Decreased activities of apolipoprotein m promoter are associated with the susceptibility to coronary artery diseases
    Lu Zheng
    1 Comprehensive Laboratory, Third Affiliated Hospital of Soochow University, Changzhou 213003, China
    Int J Med Sci 11:365-72. 2014
  3. pmc TO901317 regulating apolipoprotein M expression mediates via the farnesoid X receptor pathway in Caco-2 cells
    Chunhua Zhu
    Department of Cardiothoracic Surgery, Third Affiliated Hospital of Suzhou University, Changzhou 213003, P R China
    Lipids Health Dis 10:199. 2011
  4. pmc Impaired plasma lipid profiles in acute hepatitis
    Libo Luo
    First People s Hospital of Changzhou, Jiangsu 213003, China
    Lipids Health Dis 9:5. 2010
  5. pmc Increased plasma apoM levels in the patients suffered from hepatocellular carcinoma and other chronic liver diseases
    Jingting Jiang
    Department of Tumor Biological Treatment, The Third Affiliated Hospital of Suzhou University, Changzhou 213003, PR China
    Lipids Health Dis 7:25. 2008
  6. ncbi request reprint Down-regulation of apolipoprotein M expression is mediated by phosphatidylinositol 3-kinase in HepG2 cells
    Ning Xu
    Section of Clinical Chemistry and Pharmacology, Department of Laboratory Medicine, Lunds University, S 221 85 Lund, Sweden
    Biochim Biophys Acta 1761:256-60. 2006
  7. ncbi request reprint Suppression of apolipoprotein M expression and secretion in alloxan-diabetic mouse: Partial reversal by insulin
    Ning Xu
    Division of Clinical Chemistry and Pharmacology, Institute of Laboratory Medicine, Lund University, Lund, S 221 85 Lund, Sweden
    Biochem Biophys Res Commun 342:1174-7. 2006
  8. ncbi request reprint Expression pattern of apolipoprotein M during mouse and human embryogenesis
    Xiao Ying Zhang
    Laboratory of Molecular Medicine, The Third Affiliated Hospital, Suzhou University, Changzhou, China
    Acta Histochem 106:123-8. 2004
  9. pmc Expression and localization of apolipoprotein M in human colorectal tissues
    Guanghua Luo
    Comprehensive Laboratory, Third Affiliated Hospital, Suzhou University, Changzhou, China
    Lipids Health Dis 9:102. 2010
  10. doi request reprint Expression of apolipoprotein M in human hepatocellular carcinoma tissues
    Jingting Jiang
    Department of Tumor Biological Treatment, The Third Affiliated Hospital, Soochow University, Jiangsu Changzhou, China
    Acta Histochem 113:53-7. 2011

Collaborators

Detail Information

Publications50

  1. pmc Determination of single-nucleotide polymorphism in the proximal promoter region of apolipoprotein M gene in coronary artery diseases
    Lu Zheng
    Comprehensive Laboratory, The Third Affiliated Hospital, Suzhou University, Changzhou China
    Int J Gen Med 2:177-82. 2009
    ..In the present studies, we investigated the SNP T-778C of apoM gene in CAD patients and controls in the Han Chinese population. Moreover we examined whether serum apoM levels could be influenced by this promoter mutation...
  2. pmc Decreased activities of apolipoprotein m promoter are associated with the susceptibility to coronary artery diseases
    Lu Zheng
    1 Comprehensive Laboratory, Third Affiliated Hospital of Soochow University, Changzhou 213003, China
    Int J Med Sci 11:365-72. 2014
    ....
  3. pmc TO901317 regulating apolipoprotein M expression mediates via the farnesoid X receptor pathway in Caco-2 cells
    Chunhua Zhu
    Department of Cardiothoracic Surgery, Third Affiliated Hospital of Suzhou University, Changzhou 213003, P R China
    Lipids Health Dis 10:199. 2011
    ..In the present study we further investigated regulation of apoM expression in Caco-2 cells stimulated by a liver X receptor (LXR) agonist, TO901317...
  4. pmc Impaired plasma lipid profiles in acute hepatitis
    Libo Luo
    First People s Hospital of Changzhou, Jiangsu 213003, China
    Lipids Health Dis 9:5. 2010
    ..It may conclude that examinations of plasma lipid profile could be considered as a clinical index to reflect liver damage in the active phase of hepatitis...
  5. pmc Increased plasma apoM levels in the patients suffered from hepatocellular carcinoma and other chronic liver diseases
    Jingting Jiang
    Department of Tumor Biological Treatment, The Third Affiliated Hospital of Suzhou University, Changzhou 213003, PR China
    Lipids Health Dis 7:25. 2008
    ..To determine plasma apolipoprotein M (apoM) levels and other lipid profiles in hepatocellular carcinoma (HCC) patients compared to other chronic liver diseases and normal subjects...
  6. ncbi request reprint Down-regulation of apolipoprotein M expression is mediated by phosphatidylinositol 3-kinase in HepG2 cells
    Ning Xu
    Section of Clinical Chemistry and Pharmacology, Department of Laboratory Medicine, Lunds University, S 221 85 Lund, Sweden
    Biochim Biophys Acta 1761:256-60. 2006
    ..In conclusion, this study shows that apoM expression is regulated by PI3-kinase in HepG2-cells...
  7. ncbi request reprint Suppression of apolipoprotein M expression and secretion in alloxan-diabetic mouse: Partial reversal by insulin
    Ning Xu
    Division of Clinical Chemistry and Pharmacology, Institute of Laboratory Medicine, Lund University, Lund, S 221 85 Lund, Sweden
    Biochem Biophys Res Commun 342:1174-7. 2006
    ..Based on these results, we suggest that insulin regulates apoM synthesis in vivo and, therefore, that the reduction of apoM expression is a general phenomenon in diabetes models...
  8. ncbi request reprint Expression pattern of apolipoprotein M during mouse and human embryogenesis
    Xiao Ying Zhang
    Laboratory of Molecular Medicine, The Third Affiliated Hospital, Suzhou University, Changzhou, China
    Acta Histochem 106:123-8. 2004
    ..ApoM was also detected in stomach and skeletal muscle in early stages of embryogenesis (3-5 months)...
  9. pmc Expression and localization of apolipoprotein M in human colorectal tissues
    Guanghua Luo
    Comprehensive Laboratory, Third Affiliated Hospital, Suzhou University, Changzhou, China
    Lipids Health Dis 9:102. 2010
    ..In the present study, we therefore examined apoM expression in human colorectal tissues including cancer tissues, cancer adjacent normal tissues, polyp tissues and normal mucosa as well as inflammatory mucosa...
  10. doi request reprint Expression of apolipoprotein M in human hepatocellular carcinoma tissues
    Jingting Jiang
    Department of Tumor Biological Treatment, The Third Affiliated Hospital, Soochow University, Jiangsu Changzhou, China
    Acta Histochem 113:53-7. 2011
    ..The clinical significance of apoM in relation to HCC still needs further investigation...
  11. ncbi request reprint Transforming growth factor-beta down-regulates apolipoprotein M in HepG2 cells
    Ning Xu
    Department of Clinical Chemistry, Institute of Laboratory Medicine, University Hospital of Lund, Klinikgatan 19, S 221 85 Lund, Sweden
    Biochim Biophys Acta 1683:33-7. 2004
    ..Further, all four cytokines had more pronounced effects on apoM mRNA expression than apoB mRNA expression. The present study suggested that apoM, like apoB, may be involved in the hepatic lipoprotein assembly in vivo...
  12. doi request reprint Palmitic acid suppresses apolipoprotein M gene expression via the pathway of PPARβ/δ in HepG2 cells
    Guanghua Luo
    Comprehensive Laboratory, The Third Affiliated Hospital of Soochow University, Changzhou 213003, PR China
    Biochem Biophys Res Commun 445:203-7. 2014
    ....
  13. ncbi request reprint Leptin inhibits apolipoprotein M transcription and secretion in human hepatoma cell line, HepG2 cells
    Guanghua Luo
    Laboratory of Molecular Medicine, The Third Affiliated Hospital, Suzhou University, Changzhou 213003, China
    Biochim Biophys Acta 1734:198-202. 2005
    ..The mechanism on the contradictory effects of leptin on apoM expression in vivo and in vitro needs further investigation...
  14. ncbi request reprint Specific tissue expression and cellular localization of human apolipoprotein M as determined by in situ hybridization
    Xiao Ying Zhang
    Laboratory of Molecular Medicine, The Third Affiliated Hospital, Suzhou University, Changzhou, China
    Acta Histochem 105:67-72. 2003
    ..The present study helps to elucidate the pathophysiological functions of apoM in vivo...
  15. pmc Effects of simvastatin on apolipoprotein M in vivo and in vitro
    Xiaoying Zhang
    Division of Clinical Chemistry and Pharmacology, Department of Laboratory Medicine, Lund University, S 221 85 Lund, Sweden
    Lipids Health Dis 10:112. 2011
    ..To investigate effects of lipid lowering drug, simvastatin, on apolipoprotein M expression in the hyperlipidemic mice and in hepatic cell line, HepG2 cells...
  16. doi request reprint Liver X receptor agonist downregulates hepatic apoM expression in vivo and in vitro
    Xiaoying Zhang
    Comprehensive Laboratory, The Third Affiliated Hospital of Suzhou University, Changzhou 213003, China
    Biochem Biophys Res Commun 371:114-7. 2008
    ..The combination of RA and T0901317 showed additive effects, which suggests that apoM expression can be modulated by LXR/RXR pathway...
  17. ncbi request reprint Both leptin and leptin-receptor are essential for apolipoprotein M expression in vivo
    Ning Xu
    Department of Clinical Chemistry, Institute of Laboratory Medicine, University Hospital of Lund, S 221 85 Lund, Sweden
    Biochem Biophys Res Commun 321:916-21. 2004
    ..We conclude that both leptin and leptin-receptor are essential for the apoM expression, indicating that leptin is physiologically regulating apoM synthesis in vivo...
  18. ncbi request reprint Hyperglycemia down-regulates apolipoprotein M expression in vivo and in vitro
    Xiaoying Zhang
    Comprehensive Laboratory, The Third Affiliated Hospital, Suzhou University, Changzhou 213003, China
    Biochim Biophys Acta 1771:879-82. 2007
    ..However, in HepG2 cells both glucose and insulin markedly inhibited apoM expression these effects were additive. Thus, the possible effects of insulin in vivo seem to be mediated indirectly...
  19. ncbi request reprint [Apolipoprotein M expression in human colorectal cancer tissues and its clinicopathological relevance]
    Qin Feng Mu
    Comprehensive Laboratory, The Third Affiliated Hospital, Suzhou University, Jiangsu Changzhou 213003, China
    Zhonghua Wei Chang Wai Ke Za Zhi 15:855-8. 2012
    ..To investigate the mRNA and protein expression levels of apolipoprotein M (apoM) in the human colorectal cancer tissues, and to explore its clinical relevance...
  20. ncbi request reprint Immunochemical staining of MT2-MMP correlates positively to angiogenesis of human esophageal cancer
    Lujun Chen
    Comprehensive Laboratory, Third Affiliated Hospital of Suzhou University, Jiangsu, Changzhou, China
    Anticancer Res 30:4363-8. 2010
    ....
  21. pmc Lipids changes in liver cancer
    Jing Ting Jiang
    Department of Tumor Biological Treatment, The Third Affiliated Hospital, Suzhou University, Changzhou, China
    J Zhejiang Univ Sci B 8:398-409. 2007
    ..In this review we summarize the clinical significance of lipid and lipoprotein metabolism under liver cancer...
  22. pmc Metabolism of high density lipoproteins in liver cancer
    Jing Ting Jiang
    Department of Tumor Biological Treatment, The Third Affiliated Hospital of Suzhou University, Changzhou 213003, Jiangsu Province, China
    World J Gastroenterol 13:3159-63. 2007
    ..It depends on the integrity of cellular function of liver, which ensures homeostasis of lipid and lipoprotein metabolism. When liver cancer occurs these processes are impaired and high-density lipoproteins are changed...
  23. doi request reprint Immunolocalisation of tissue factor in esophageal cancer is correlated with intratumoral angiogenesis and prognosis of the patient
    Lujun Chen
    Comprehensive Laboratory, The Third Affiliated Hospital of Suzhou University, Jiangsu Changzhou 213003, China
    Acta Histochem 112:233-9. 2010
    ..0056). It is concluded that TF immunopositivity in ESCC tissues is strongly correlated to the intratumoral angiogenesis and to poor patient prognosis...
  24. pmc Influence of liver cancer on lipid and lipoprotein metabolism
    Jingting Jiang
    Section of Clinical Chemistry and Pharmacology, Institute of Laboratory Medicine, Lund University, S 221 85 Lund, Sweden
    Lipids Health Dis 5:4. 2006
    ..LDL and HDL have therefore been proposed as a carrier for the water-insoluble anti-cancer agents...
  25. ncbi request reprint [A novel method of detecting mitochondrial C1494T and A1555G mutations by using the base-quenched probe technique in a single PCR assay]
    Lu Zheng
    Comprehensive Laboratoty, Third Affiliated Hospital, Soochow University, Changzhou 213003, China
    Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 47:326-9. 2012
    ..In the present study we describe a new method to detect the mitochondrial DNA (mtDNA) mutations A1555G and C1494T by using the base-quenched probe technique in a single PCR reaction...
  26. ncbi request reprint Mechanisms and significance of lipoprotein(a) in hepatocellular carcinoma
    Jing Ting Jiang
    Department of Tumor Biological Treatment, Third Affiliated Hospital, Suzhou University, Changzhou 213003, China
    Hepatobiliary Pancreat Dis Int 8:25-8. 2009
    ..Hepatocellular carcinoma is one of the most common fatal malignant tumors in China and in other Southeast Asian countries. It has been demonstrated that plasma lipid profiles are changed in liver cancer...
  27. pmc Lipid synthesis and secretion in HepG2 cells is not affected by ACTH
    Maria Skoog
    Section of Clinical Chemistry and Pharmacology, Institute of Laboratory Medicine, Lunds University, S 22185 Lund, Sweden
    Lipids Health Dis 9:48. 2010
    ..The present study suggests that ACTH lowers plasma lipids in humans mainly mediated by the inhibition of apoB synthesis and did not via the reduced lipid synthesis...
  28. ncbi request reprint A novel pattern of pp65-positive cytomegalic endothelial cells circulating in peripheral blood from a renal transplant recipient
    Qing Ye
    Comprehensive Laboratory, The Third Affiliated Hospital, Suzhou University, Changzhou 213003, China
    Acta Histochem 106:107-10. 2004
    ..It is suggested that these novel localization patterns of CEC may play a role in the host defense in patients infected with HCMV, but the exact relation between HCMV infection and CEC formation needs further investigation...
  29. doi request reprint Genotyping of single nucleotide polymorphisms using base-quenched probe: a method does not invariably depend on the deoxyguanosine nucleotide
    Guanghua Luo
    Comprehensive Laboratory, Third Affiliated Hospital, Suzhou University, Changzhou 213003, China
    Anal Biochem 386:161-6. 2009
    ..It is concluded that this method is precise, simple, and economic as well as suitable for large-scale genotyping studies...
  30. ncbi request reprint Expression of MMP-10 in lung cancer
    Xiaoying Zhang
    Comprehensive Laboratory, The Third Affiliated Hospital, Suzhou University, Changzhou 213003, China
    Anticancer Res 27:2791-5. 2007
    ..MMP-10 is one of the most important and well-characterized members of the MMP family. In the present study, we examined MMP-10 mRNA and protein levels in non-small cell lung cancer (NSCLC)...
  31. ncbi request reprint Correlation of apolipoprotein M with leptin and cholesterol in normal and obese subjects
    Ning Xu
    Department of Clinical Chemistry, Institute of Laboratory Medicine, University Hospital of Lund, S 221 85 Lund, Sweden
    J Nutr Biochem 15:579-82. 2004
    ..These two parameters yielded a value of r(2) = 0.28, thereby explaining approximately 30% of the variance in apoM. Hence, we show that apoM is positively related to leptin and negatively related to cholesterol in humans...
  32. ncbi request reprint Mutations of PTEN gene in gliomas correlate to tumor differentiation and short-term survival rate
    Yiling Yang
    Section of Clinical Chemistry and Pharmacology, Institute of Laboratory Medicine, Lunds University, S 221 85 Lund, Sweden
    Anticancer Res 30:981-5. 2010
    ..038, odds ratio=7.80), respectively. The present study suggests that PTEN mutations are late events in the malignant progression of glioma and the occurrence of PTEN mutations are significantly correlated to patients' short-term survival...
  33. ncbi request reprint Clinical application of determining serum AFP-IgM complexes for diagnosis of small hepatocellular carcinoma
    Jingting Jiang
    Department of Tumor Biological Treatment, The Third Affiliated Hospital, Soochow University, Changzhou 213003, PR China
    Anticancer Res 31:687-91. 2011
    ..4 ± 571.8 AU/ml) than in the patients with tumor diameter >3 cm (604.9 ± 749.9 AU/ml). It is concluded that determining serum levels of both AFP-IgM immune complex and AFP may have potential benefit for the diagnosis of small HCC...
  34. pmc Apolipoprotein M
    Guanghua Luo
    Department of Clinical Chemistry, Institute of Laboratory Medicine, University Hospital of Lund, S 221 85 Lund, Sweden
    Lipids Health Dis 3:21. 2004
    ..ApoM concentration in plasma is positively correlated to leptin level in obese subjects. These may suggest that apoM is related to the initiation and progression of MODY3 and/or obesity...
  35. ncbi request reprint Effects of platelet-activating factor, tumor necrosis factor, and interleukin-1alpha on the expression of apolipoprotein M in HepG2 cells
    Ning Xu
    Department of Clinical Chemistry, University Hospital of Lund, Lund, S 221 85, Sweden
    Biochem Biophys Res Commun 292:944-50. 2002
    ..The cellular mechanism of the effects of PAF or Lexipafant on apoM metabolism requires further investigations...
  36. ncbi request reprint Treatment of advanced gastric cancer by chemotherapy combined with autologous cytokine-induced killer cells
    Jingting Jiang
    The Third Affiliated Hospital, Suzhou University, Changzhou 213003, China
    Anticancer Res 26:2237-42. 2006
    ..It is concluded that chemotherapy plus CIK cells has obvious benefits for patients who suffer from advanced gastric cancers...
  37. doi request reprint A novel method of detecting alpha-1 antitrypsin deficiency of Z mutant (GAG(342)AAG) in a single PCR reaction using base-quenched probe
    Li Qin
    Comprehensive Laboratory, Changzhou Key Lab of Individualized Diagnosis and Treatment Associated with High Technology Research, The Third Affiliated Hospital of Soochow University, Changzhou 213003, China
    Clin Chim Acta 427:29-33. 2014
    ..Of all the deficiency alleles, Z mutant is the most common variant and causes severe complications. Here, we described a novel and quick method to detect Z mutant using the base-quenched probe technique in only one single PCR reaction...
  38. ncbi request reprint Association of prothrombin and protein S with plasma triglyceride-rich lipoproteins in humans after test meals rich in milk fat or soybean oil
    Li Zhou
    Gastroenterology Division, Department of Medicine, Lund University, Tornavägen, Sweden
    Thromb Res 108:209-13. 2002
    ..In the present study, we examined the effects of saturated and unsaturated fat meals on the association of prothrombin and protein S with TG-rich lipoproteins in vivo...
  39. ncbi request reprint ACTH reduces the rise in ApoB-48 levels after fat intake
    Maria Skoog
    Division of Clinical Chemistry and Pharmacology, Department of Laboratory Medicine, ILM, Lunds University, S 221 85 Lund, Sweden
    Atherosclerosis 191:433-9. 2007
    ..This study confirms earlier reports on the lipid-lowering effects of ACTH and supports our theory, based on in vitro studies, that the lipid-lowering effects of ACTH administration in man involves an inhibition of ApoB production...
  40. ncbi request reprint Immunohistochemical localization of programmed death-1 ligand-1 (PD-L1) in gastric carcinoma and its clinical significance
    Changping Wu
    The Third Affiliated Hospital of Suzhou University, Changzhou 213003, China
    Acta Histochem 108:19-24. 2006
    ....
  41. ncbi request reprint Identification of human intestinal alkaline sphingomyelinase as a novel ecto-enzyme related to the nucleotide phosphodiesterase family
    Rui Dong Duan
    Gastroenterology Laboratory, Biomedical Center, B11, Lund University, S 221 84 Lund, Sweden
    J Biol Chem 278:38528-36. 2003
    ..In conclusion, we identified the amino acid and cDNA sequences of human intestinal alk-SMase, and found that it is a novel ecto-enzyme related to the NPP family with specific features essential for its SMase activity...
  42. ncbi request reprint Heterogeneous transportation of alpha1B-adrenoceptor in living cells
    Yinghua Guan
    Beijing National Laboratory for Molecular Sciences, State Key Laboratory for Structural Chemistry of Unstable and Stable Species, and Department of Chemical Biology, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China
    Biophys Chem 127:149-54. 2007
    ....
  43. ncbi request reprint Nucleotide sequence of the p53 cDNA of beluga whale (Delphinapterus leucas)
    Ning Xu
    Division of Molecular Epidemiology, Kobe University Graduate School of Medicine, 7 5 1, Kusunoki cho, Chuo Ku, Japan
    Gene 288:159-66. 2002
    ..The similarities with the former two animals at the amino acid level were also more than 85%. Lower similarity of the beluga whale p53 gene was also found with those of lower tetrapods, fish and invertebrates...
  44. ncbi request reprint Role of endothelin-1 and nitric oxide bioavailability in transplant-related vascular injury: comparative effects of rapamycin and cyclosporine
    Danny Ramzy
    Heart Transplant Program, Toronto General Hospital, University Health Network, University of Toronto, Toronto, Ontario, Canada
    Circulation 114:I214-9. 2006
    ..We previously demonstrated that CyA results in impairment of nitric oxide bioavailability and enhanced sensitivity to endothelin-1 (ET-1). In this study, we evaluated rapamycin (SRL) for its effects on the endothelium...
  45. ncbi request reprint Time-dependent reversal of sepsis-induced PMN uptake and lung vascular injury by expression of CD18 antagonist
    Ning Xu
    Department of Pharmacology, College of Medicine, The University of Illinois, 835 S Wolcott Avenue, Chicago, IL 60612, USA
    Am J Physiol Lung Cell Mol Physiol 282:L796-802. 2002
    ..The results support the model that initial engagement of CD18 integrins enables the further recruitment of additional PMN into lung tissues such that PMN continue to sequester and migrate after E. coli challenge...
  46. ncbi request reprint The transport of alpha(1A)-adrenergic receptor with 33-nm step size in live cells
    Zhang Yi Liang
    State Key Laboratory for Structural Chemistry of Unstable and Stable Species, Department of Chemical Biology, College of Chemistry and Molecular Engineering, Peking University, Beijing, China
    Biochem Biophys Res Commun 353:231-7. 2007
    ..These results provided insight into the mechanism of GPCR transport in vivo...
  47. ncbi request reprint [Inhibition of HBV core antigen gene expression in human embryonic kidney cell line AD293 by plasmid-based RNAi]
    Ning Xu
    Institute of Infectious Diseases, The First Affiliated Hospital, Key Laboratory of Infectious Diseases Ministry of Health, College of Medicine, Zhejiang University, Hangzhou 310003, China
    Zhejiang Da Xue Xue Bao Yi Xue Ban 34:104-9. 2005
    ..To inhibit HBV core antigen gene expression with plasmid-based RNAi...
  48. ncbi request reprint [Application of PCR-based tRNAval Pol III-shRNA expression cassettes in screening of efficient siRNA for inhibiting hepatitis B virus]
    Xiu cheng Pan
    Institute of Infectious Disease, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310003, China
    Zhejiang Da Xue Xue Bao Yi Xue Ban 35:154-60. 2006
    ..To screen efficient siRNA for inhibiting hepatitis B virus using the technique of PCR-based tRNA(val) Pol III-shRNA expression cassettes (SECs)...
  49. doi request reprint Human alpha-defensin-1 inhibits growth of human lung adenocarcinoma xenograft in nude mice
    Ning Xu
    State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, West China Medical School, Sichuan University, Chengdu, Sichuan, People s Republic of China
    Mol Cancer Ther 7:1588-97. 2008
    ..The antiangiogenesis effect of HNP1 may contribute to its inhibitory activity in vivo, and HNP1 might involve the host immune response to tumor. These findings provide a rationale for developing HNP1-based gene therapy for cancer...
  50. pmc Inhibition of hepatitis B virus surface antigen expression by small hairpin RNA in vitro
    Zheng Gang Yang
    Institute of Infectious Diseases, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310003, Zhejiang Province, China
    World J Gastroenterol 11:498-502. 2005
    ..To explore the anti-hepatitis B virus effect of RNA interference (RNAi) using small hairpin RNA (shRNA) expression vector...