Petter Vikman

Summary

Affiliation: Lund University
Country: Sweden

Publications

  1. doi request reprint RNA sequencing: current and prospective uses in metabolic research
    Petter Vikman
    Diabetes and EndocrinologyDepartment of Clinical Sciences, Malmo University Hospital, CRC, Lund University, Building 60, Level 13, Entrance 72, S 205 02 Malmo, Skåne, Sweden
    J Mol Endocrinol 53:R93-101. 2014
  2. ncbi request reprint Transcriptional regulation of inflammatory and extracellular matrix-regulating genes in cerebral arteries following experimental subarachnoid hemorrhage in rats. Laboratory investigation
    Petter Vikman
    Department of Clinical Sciences, Experimental Vascular Research, Lund, Sweden
    J Neurosurg 107:1015-22. 2007
  3. ncbi request reprint Gene expression and molecular changes in cerebral arteries following subarachnoid hemorrhage in the rat
    Petter Vikman
    Department of Clinical Sciences, Experimental Vascular Research, Lunds universitet, Lund, Sweden
    J Neurosurg 105:438-44. 2006
  4. ncbi request reprint Gene expression profiling in the human middle cerebral artery after cerebral ischemia
    P Vikman
    Department of Experimental Vascular Research, Institution of Medicine, Lund University, Lund, Sweden
    Eur J Neurol 13:1324-32. 2006
  5. ncbi request reprint Cerebrovascular ETB, 5-HT1B, and AT1 receptor upregulation correlates with reduction in regional CBF after subarachnoid hemorrhage
    Saema Ansar
    Department of Clinical Sciences, Division of Experimental Vascular Research, Lund University, 221 84 Lund, Sweden
    Am J Physiol Heart Circ Physiol 293:H3750-8. 2007
  6. ncbi request reprint Cerebral ischemia induces transcription of inflammatory and extracellular-matrix-related genes in rat cerebral arteries
    Petter Vikman
    Department of Clinical Sciences, Experimental Vascular Research, BMC A13, 221 84, Lund, Sweden
    Exp Brain Res 183:499-510. 2007
  7. pmc Protein kinase C inhibition attenuates vascular ETB receptor upregulation and decreases brain damage after cerebral ischemia in rat
    Marie Henriksson
    Division of Experimental Vascular Research, Department of Clinical Sciences in Lund, Lund University, Sweden
    BMC Neurosci 8:7. 2007
  8. pmc Inhibition of PKC activity blocks the increase of ETB receptor expression in cerebral arteries
    Marie Henriksson
    Division of Experimental Vascular Research, Clinical Sciences, Lund University, Lund, Sweden
    BMC Pharmacol 6:13. 2006
  9. ncbi request reprint MEK1/2 inhibition attenuates vascular ETA and ETB receptor alterations after cerebral ischaemia
    Marie Henriksson
    Division of Experimental Vascular Research, Department of Clinical Sciences in Lund, BMC A13, Lund University, Lund, 221 84 Sweden
    Exp Brain Res 178:470-6. 2007
  10. pmc Lipid-soluble cigarette smoking particles induce expression of inflammatory and extracellular-matrix-related genes in rat cerebral arteries
    Petter Vikman
    Department of Clinical Sciences, Experimental Vascular Research, Lund, Sweden
    Vasc Health Risk Manag 5:333-41. 2009

Collaborators

Detail Information

Publications20

  1. doi request reprint RNA sequencing: current and prospective uses in metabolic research
    Petter Vikman
    Diabetes and EndocrinologyDepartment of Clinical Sciences, Malmo University Hospital, CRC, Lund University, Building 60, Level 13, Entrance 72, S 205 02 Malmo, Skåne, Sweden
    J Mol Endocrinol 53:R93-101. 2014
    ..The only drawback is the large data amounts produced, which together with the complexity of the data can make a researcher spend far more time on analysis than performing the actual experiment. ..
  2. ncbi request reprint Transcriptional regulation of inflammatory and extracellular matrix-regulating genes in cerebral arteries following experimental subarachnoid hemorrhage in rats. Laboratory investigation
    Petter Vikman
    Department of Clinical Sciences, Experimental Vascular Research, Lund, Sweden
    J Neurosurg 107:1015-22. 2007
    ....
  3. ncbi request reprint Gene expression and molecular changes in cerebral arteries following subarachnoid hemorrhage in the rat
    Petter Vikman
    Department of Clinical Sciences, Experimental Vascular Research, Lunds universitet, Lund, Sweden
    J Neurosurg 105:438-44. 2006
    ..The authors investigated early changes in the cerebral arteries of rats that occur after subarachnoid hemorrhage (SAH)...
  4. ncbi request reprint Gene expression profiling in the human middle cerebral artery after cerebral ischemia
    P Vikman
    Department of Experimental Vascular Research, Institution of Medicine, Lund University, Lund, Sweden
    Eur J Neurol 13:1324-32. 2006
    ..Gene expression studies in the human MCA leading to the ischemic region is similar to that seen after MCA occlusion in rats. We found new genes that support the dynamic changes that occur in the MCA distributing to the ischemic region...
  5. ncbi request reprint Cerebrovascular ETB, 5-HT1B, and AT1 receptor upregulation correlates with reduction in regional CBF after subarachnoid hemorrhage
    Saema Ansar
    Department of Clinical Sciences, Division of Experimental Vascular Research, Lund University, 221 84 Lund, Sweden
    Am J Physiol Heart Circ Physiol 293:H3750-8. 2007
    ..These changes occur in parallel with a successive decrease in CBF. Thus there is a temporal correlation between the changes in receptor expression and CBF reduction, suggesting a linkage...
  6. ncbi request reprint Cerebral ischemia induces transcription of inflammatory and extracellular-matrix-related genes in rat cerebral arteries
    Petter Vikman
    Department of Clinical Sciences, Experimental Vascular Research, BMC A13, 221 84, Lund, Sweden
    Exp Brain Res 183:499-510. 2007
    ....
  7. pmc Protein kinase C inhibition attenuates vascular ETB receptor upregulation and decreases brain damage after cerebral ischemia in rat
    Marie Henriksson
    Division of Experimental Vascular Research, Department of Clinical Sciences in Lund, Lund University, Sweden
    BMC Neurosci 8:7. 2007
    ..The present study aimed to examine the effect of the PKC inhibitor Ro-32-0432 on endothelin receptor upregulation, infarct volume and neurology outcome after middle cerebral artery occlusion in rat...
  8. pmc Inhibition of PKC activity blocks the increase of ETB receptor expression in cerebral arteries
    Marie Henriksson
    Division of Experimental Vascular Research, Clinical Sciences, Lund University, Lund, Sweden
    BMC Pharmacol 6:13. 2006
    ..Furthermore, immunohistochemistry was used to demonstrate the ETB receptor protein distribution in the MCA and Western blot to measure which of the PKC subtypes that were affected by the inhibitors...
  9. ncbi request reprint MEK1/2 inhibition attenuates vascular ETA and ETB receptor alterations after cerebral ischaemia
    Marie Henriksson
    Division of Experimental Vascular Research, Department of Clinical Sciences in Lund, BMC A13, Lund University, Lund, 221 84 Sweden
    Exp Brain Res 178:470-6. 2007
    ..The vascular effects of U0126 provide new perspective on possible mechanisms of actions of MAPK inhibition in cerebral ischaemia...
  10. pmc Lipid-soluble cigarette smoking particles induce expression of inflammatory and extracellular-matrix-related genes in rat cerebral arteries
    Petter Vikman
    Department of Clinical Sciences, Experimental Vascular Research, Lund, Sweden
    Vasc Health Risk Manag 5:333-41. 2009
    ..Cigarette smoking is one of the strongest risk factors for stroke. However, the underlying molecular mechanisms that smoke leads to the pathogenesis of stroke are incompletely understood...
  11. pmc Discriminative Prediction of A-To-I RNA Editing Events from DNA Sequence
    Jiangming Sun
    Department of Clinical Sciences in Malmo, Unit of Molecular Metabolism, Lund University Diabetes Centre, CRC, Malmo, Sweden
    PLoS ONE 11:e0164962. 2016
    ..g., by targeted deep sequencing. In conclusion, the approach described here is a useful tool to identify potential A-to-I RNA editing events without the requirement of extensive RNA sequencing...
  12. doi request reprint A systems genetics approach identifies genes and pathways for type 2 diabetes in human islets
    Jalal Taneera
    Lund University Diabetes Center, Department of Clinical Sciences, Diabetes and Endocrinology, Skåne University Hospital Malmö, Lund University, Malmo 20502, Sweden
    Cell Metab 16:122-34. 2012
    ..The data present a global map of genes associated with islet dysfunction and demonstrate the value of systems genetics for the identification of genes potentially involved in T2D...
  13. pmc Smoking particles enhance endothelin A and endothelin B receptor-mediated contractions by enhancing translation in rat bronchi
    Bengt W Granström
    Department of Medicine, Clinical Sciences, Lund University, Lund, Sweden
    BMC Pulm Med 6:6. 2006
    ..To study the effect of smoking on the endothelin system in rat airways, bronchial segments were exposed to DMSO-soluble smoking particles (DSP) from cigarette smoke, to nicotine and to DMSO, respectively...
  14. ncbi request reprint Angiotensin II-induced vasodilatation in cerebral arteries is mediated by endothelium-derived hyperpolarising factor
    Angelica Wackenfors
    Division of Experimental Vascular Research, Department of Clinical Science, Lund University Hospital, Lund, Sweden
    Eur J Pharmacol 531:259-63. 2006
    ..The angiotensin II dilatation was blocked by the angiotensin AT1 and AT2 receptor blockers candesartan and PD 123319. Both angiotensin AT1 and AT2 receptors were detected on the endothelium by immunohistochemistry...
  15. doi request reprint Serotonin (5-HT) receptor 2b activation augments glucose-stimulated insulin secretion in human and mouse islets of Langerhans
    Hedvig Bennet
    Lund University Diabetes Centre, Department of Clinical Sciences, Unit of Diabetes and Celiac Disease, Clinical Research Centre, Jan Waldenströms gata 35, Clinical Research Centre House 91 10, Skåne University Hospital Malmö, SE 20502, Malmo, Sweden
    Diabetologia 59:744-54. 2016
    ..The aim of the present study was to explore the role of the 5-HT2B receptor in the regulation of insulin secretion in mouse and human islets, as well as in clonal INS-1(832/13) cells...
  16. doi request reprint Complement inhibitor CD55 governs the integrity of membrane rafts in pancreatic beta cells, but plays no role in insulin secretion
    Vini Nagaraj
    Department of Clinical Sciences, Lund University, SE 20502 Malmo, Sweden
    Biochem Biophys Res Commun 460:518-24. 2015
    ..However CD55 does not interfere with insulin secretion in beta cells, which is in sharp contrast to the action of the complement inhibitor CD59. ..
  17. pmc Global genomic and transcriptomic analysis of human pancreatic islets reveals novel genes influencing glucose metabolism
    João Fadista
    Lund University Diabetes Centre, Department of Clinical Sciences, Skåne University Hospital Malmö, Lund University, 20502 Malmo, Sweden
    Proc Natl Acad Sci U S A 111:13924-9. 2014
    ..Taken together, this study provides new insights into the complexity of gene regulation in human pancreatic islets and better understanding of how genetic variation can influence glucose metabolism. ..
  18. pmc TCF7L2 is a master regulator of insulin production and processing
    Yuedan Zhou
    Department of Clinical Sciences, CRC, Lund University, Malmo 20502, Sweden
    Hum Mol Genet 23:6419-31. 2014
    ..These multiple targets in key pathways may explain why TCF7L2 has emerged as the gene showing one of the strongest associations with T2D. ..
  19. ncbi request reprint HDAC7 is overexpressed in human diabetic islets and impairs insulin secretion in rat islets and clonal beta cells
    Mahboubeh Daneshpajooh
    Epigenetics and Diabetes Unit, Department of Clinical Sciences, Lund University Diabetes Centre, Lund University, CRC, 20502, Malmo, Sweden
    Diabetologia 60:116-125. 2017
    ..Our aim was to investigate the role of HDAC7 in human and rat pancreatic islets and clonal INS-1 beta cells (INS-1 832/13)...
  20. pmc Influence of Familial Renal Glycosuria Due to Mutations in the SLC5A2 Gene on Changes in Glucose Tolerance over Time
    Emilia Ottosson-Laakso
    Diabetes and Endocrinology, Department of Clinical Sciences, Lund University, Malmo, Sweden
    PLoS ONE 11:e0146114. 2016
    ..In conclusion, in this family with familial glycosuria we did not find any evidence that chronic loss of glucose in the urine would protect from deterioration of the glucose tolerance over time. ..