Tore Saxne

Summary

Affiliation: Lund University Hospital
Country: Sweden

Publications

  1. pmc Hormone replacement therapy, calcium and vitamin D3 versus calcium and vitamin D3 alone decreases markers of cartilage and bone metabolism in rheumatoid arthritis: a randomized controlled trial [ISRCTN46523456]
    Helena Forsblad d'Elia
    Department of Rheumatology and Inflammation Research, The Sahlgrenska Academy at Goteborg University, Goteborg, Sweden
    Arthritis Res Ther 6:R457-68. 2004
  2. pmc Serum cartilage oligomeric matrix protein (COMP) decreases in rheumatoid arthritis patients treated with infliximab or etanercept
    Meliha Crnkic
    Department of Rheumatology, Lund University Hospital, Lund, Sweden
    Arthritis Res Ther 5:R181-5. 2003
  3. pmc Treatment with TNF blockers and mortality risk in patients with rheumatoid arthritis
    Lennart T H Jacobsson
    Department of Rheumatology, Malmo University Hospital, S 205 02 Malmo, Sweden
    Ann Rheum Dis 66:670-5. 2007
  4. doi Sick leave in patients with ankylosing spondylitis before and after anti-TNF therapy: a population-based cohort study
    Lars E Kristensen
    Department of Orthopedics, Musculoskeletal Sciences, Clinical Sciences Lund, Lund University, Lund, Sweden
    Rheumatology (Oxford) 51:243-9. 2012
  5. pmc Impact of concomitant DMARD therapy on adherence to treatment with etanercept and infliximab in rheumatoid arthritis. Results from a six-year observational study in southern Sweden
    Lars Erik Kristensen
    Department of Rheumatology, Lund University Hospital, Kioskgatan 3, SE 221 85 Lund, Sweden
    Arthritis Res Ther 8:R174. 2006
  6. pmc The association between antibody levels before and after 7-valent pneumococcal conjugate vaccine immunization and subsequent pneumococcal infection in chronic arthritis patients
    Johanna Nagel
    Department of Clinical Sciences, Lund, Section of Rheumatology, Lund University, and Skåne University Hospital, Kioskgatan 3, SE 221 85, Lund, Sweden
    Arthritis Res Ther 17:124. 2015
  7. pmc Disease activity level, remission and response in established rheumatoid arthritis: performance of various criteria sets in an observational cohort, treated with anti-TNF agents
    Anders Gülfe
    Dept of Rheumatology, Lund University Hospital, Lund, Sweden
    BMC Musculoskelet Disord 10:41. 2009
  8. ncbi The LUNDEX, a new index of drug efficacy in clinical practice: results of a five-year observational study of treatment with infliximab and etanercept among rheumatoid arthritis patients in southern Sweden
    Lars Erik Kristensen
    Department of Rheumatology, Lund University Hospital, Lund, Sweden
    Arthritis Rheum 54:600-6. 2006
  9. pmc Early changes in bone mineral density measured by digital X-ray radiogrammetry predict up to 20 years radiological outcome in rheumatoid arthritis
    Meliha C Kapetanovic
    Department of Clinical Sciences, Lund, Section of Rheumatology, Lund University, Kioskgatan 3, Lund SE 22185, Sweden
    Arthritis Res Ther 13:R31. 2011
  10. doi Increased serum COMP predicts mortality in SSc: results from a longitudinal study of interstitial lung disease
    Roger Hesselstrand
    Department of Rheumatology, Skane University Hospital, S 221 85 Lund, Sweden
    Rheumatology (Oxford) 51:915-20. 2012

Collaborators

Detail Information

Publications24

  1. pmc Hormone replacement therapy, calcium and vitamin D3 versus calcium and vitamin D3 alone decreases markers of cartilage and bone metabolism in rheumatoid arthritis: a randomized controlled trial [ISRCTN46523456]
    Helena Forsblad d'Elia
    Department of Rheumatology and Inflammation Research, The Sahlgrenska Academy at Goteborg University, Goteborg, Sweden
    Arthritis Res Ther 6:R457-68. 2004
    ..We suggest that biochemical markers of bone and cartilage turnover may provide a useful tool for assessing novel treatment modalities in arthritis, concerning both joint protection and prevention of osteoporosis...
  2. pmc Serum cartilage oligomeric matrix protein (COMP) decreases in rheumatoid arthritis patients treated with infliximab or etanercept
    Meliha Crnkic
    Department of Rheumatology, Lund University Hospital, Lund, Sweden
    Arthritis Res Ther 5:R181-5. 2003
    ..Serum COMP has potential as a useful marker for evaluating tissue effects of novel treatment modalities in rheumatoid arthritis...
  3. pmc Treatment with TNF blockers and mortality risk in patients with rheumatoid arthritis
    Lennart T H Jacobsson
    Department of Rheumatology, Malmo University Hospital, S 205 02 Malmo, Sweden
    Ann Rheum Dis 66:670-5. 2007
    ..To assess mortality in patients with rheumatoid arthritis (RA) treated with tumour necrosis factor (TNF) inhibitors, compared with a standard RA population...
  4. doi Sick leave in patients with ankylosing spondylitis before and after anti-TNF therapy: a population-based cohort study
    Lars E Kristensen
    Department of Orthopedics, Musculoskeletal Sciences, Clinical Sciences Lund, Lund University, Lund, Sweden
    Rheumatology (Oxford) 51:243-9. 2012
    ..To study levels of sick leave and disability pension before and after TNF-antagonist therapy in AS patients...
  5. pmc Impact of concomitant DMARD therapy on adherence to treatment with etanercept and infliximab in rheumatoid arthritis. Results from a six-year observational study in southern Sweden
    Lars Erik Kristensen
    Department of Rheumatology, Lund University Hospital, Kioskgatan 3, SE 221 85 Lund, Sweden
    Arthritis Res Ther 8:R174. 2006
    ..Concomitant MTX is associated with improved treatment continuation of biologics when compared with both TNF blockers as monotherapy and TNF blockers combined with other DMARDs...
  6. pmc The association between antibody levels before and after 7-valent pneumococcal conjugate vaccine immunization and subsequent pneumococcal infection in chronic arthritis patients
    Johanna Nagel
    Department of Clinical Sciences, Lund, Section of Rheumatology, Lund University, and Skåne University Hospital, Kioskgatan 3, SE 221 85, Lund, Sweden
    Arthritis Res Ther 17:124. 2015
    ....
  7. pmc Disease activity level, remission and response in established rheumatoid arthritis: performance of various criteria sets in an observational cohort, treated with anti-TNF agents
    Anders Gülfe
    Dept of Rheumatology, Lund University Hospital, Lund, Sweden
    BMC Musculoskelet Disord 10:41. 2009
    ..We therefore wanted to compare the performance of the DAS28, SDAI and CDAI activity indices, their activity states, their response criteria, and also compare with the ACR response criteria in an observational clinical setting...
  8. ncbi The LUNDEX, a new index of drug efficacy in clinical practice: results of a five-year observational study of treatment with infliximab and etanercept among rheumatoid arthritis patients in southern Sweden
    Lars Erik Kristensen
    Department of Rheumatology, Lund University Hospital, Lund, Sweden
    Arthritis Rheum 54:600-6. 2006
    ..To describe the use of the LUNDEX, a new index for comparing the long-term efficacy and tolerability of biologic therapies in rheumatoid arthritis (RA) patients treated in clinical practice...
  9. pmc Early changes in bone mineral density measured by digital X-ray radiogrammetry predict up to 20 years radiological outcome in rheumatoid arthritis
    Meliha C Kapetanovic
    Department of Clinical Sciences, Lund, Section of Rheumatology, Lund University, Kioskgatan 3, Lund SE 22185, Sweden
    Arthritis Res Ther 13:R31. 2011
    ..This study's objective was to investigate whether DXR-BMD loss early in the course of the disease predicts the development of joint damage in RA patients followed for up to 20 years...
  10. doi Increased serum COMP predicts mortality in SSc: results from a longitudinal study of interstitial lung disease
    Roger Hesselstrand
    Department of Rheumatology, Skane University Hospital, S 221 85 Lund, Sweden
    Rheumatology (Oxford) 51:915-20. 2012
    ..Serum COMP reflects skin fibrosis in SSc. The purpose of this study was to examine whether serum COMP reflects fibrotic lung involvement in SSc patients and to study if serum COMP predicts mortality...
  11. doi Increased cartilage turnover and circulating autoantibodies in different subsets before the clinical onset of rheumatoid arthritis
    Carl Turesson
    Correspondence to Dr Carl Turesson, Department of Rheumatology, Skane University Hospital, Södra Förstadsgatan 101, S 205 02 Malmo, Sweden
    Ann Rheum Dis 70:520-2. 2011
    ..Cartilage biomarkers, such as cartilage oligomeric matrix protein (COMP), have not been studied previously in samples collected before the diagnosis of RA...
  12. pmc Predictors of infusion reactions during infliximab treatment in patients with arthritis
    Meliha C Kapetanovic
    Department of Rheumatology, Lund University Hospital, Lund, Sweden
    Arthritis Res Ther 8:R131. 2006
    ..RA patients treated with infliximab without methotrexate, and who are positive at baseline for ANAs are at increased risk for developing infliximab-related infusion reactions...
  13. doi Decrease in sick leave among patients with rheumatoid arthritis in the first 12 months after start of treatment with tumour necrosis factor antagonists: a population-based controlled cohort study
    Tor Olofsson
    Musculoskeletal Sciences, Department of Orthopedics, Clinical Sciences Lund, Lund, Sweden
    Ann Rheum Dis 69:2131-6. 2010
    ..To investigate the effect of tumour necrosis factor (TNF) antagonist treatment of patients with rheumatoid arthritis (RA) on sick leave (SL) and disability pension (DP) in a population-based setting in southern Sweden...
  14. doi Antibody response is reduced following vaccination with 7-valent conjugate pneumococcal vaccine in adult methotrexate-treated patients with established arthritis, but not those treated with tumor necrosis factor inhibitors
    Meliha Crnkic Kapetanovic
    Department of Clinical Sciences Lund, Section of Rheumatology, Lund University, Lund, Sweden
    Arthritis Rheum 63:3723-32. 2011
    ....
  15. doi Limited impact of fibromodulin deficiency on the development of experimental skin fibrosis
    Kristofer Andréasson
    Department of Clinical Sciences Lund, Section of Rheumatology and Molecular Skeletal Biology, Lund University, Lund, Sweden
    Exp Dermatol 25:558-61. 2016
    ..We conclude that the impact of FMOD deficiency on the development of experimental skin fibrosis is limited. ..
  16. ncbi Cartilage oligomeric matrix protein: a new promising biomarker of liver fibrosis in chronic hepatitis C
    Kristofer Andréasson
    a From the Section of Rheumatology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden
    Infect Dis (Lond) 47:915-8. 2015
    ..001). After successful treatment of CHC, COMP decreased from 18 to 13 U/l (p = 0.011). We suggest that COMP is associated with the stage of liver fibrosis in CHC. The biomarker potential of COMP in CHC warrants further investigation. ..
  17. doi Extracellular matrix alterations and acute inflammation; developing in parallel during early induction of pulmonary fibrosis
    Kristina Rydell-Törmänen
    Section of Rheumatology, Department of Clinical Science, Lund University, Lund, Sweden
    Lab Invest 92:917-25. 2012
    ..A transient neutrophilia is detected and increased number of macrophages likely represents a clearance process of said neutrophils. The study suggests fibrosis initiation and acute inflammation to occur in parallel in this model...
  18. doi Bone mineral density in the hand as a predictor for mortality in patients with rheumatoid arthritis
    Christina Book
    Department of Rheumatology, Malmo University Hospital, Malmo, Sweden
    Rheumatology (Oxford) 48:1088-91. 2009
    ..A predictor for long-term prognosis might also predict increased mortality in RA. The aim of the present study was to evaluate BMD in the hand as a predictor for all-cause mortality...
  19. doi Sustained Remission Improves Physical Function in Patients with Established Rheumatoid Arthritis, and Should Be a Treatment Goal: A Prospective Observational Cohort Study from Southern Sweden
    Jon Thorkell Einarsson
    From the Department of Clinical Sciences Lund, Section of Rheumatology, Lund University, Skane University Hospital, Lund, Sweden The Parker Institute, Department of Rheumatology, Bispebjerg and Frederiksberg Hospital, the Capital Region of Copenhagen, Copenhagen, Denmark J T Einarsson, MD, Department of Clinical Sciences Lund, Section of Rheumatology, Lund University, Skåne University Hospital P Geborek, MD, PhD, Department of Clinical Sciences Lund, Section of Rheumatology, Lund University, Skåne University Hospital T Saxne, MD, PhD, Professor, Department of Clinical Sciences Lund, Section of Rheumatology, Lund University, Skåne University Hospital L E Kristensen, MD, PhD, Department of Clinical Sciences Lund, Section of Rheumatology, Lund University, Skane University Hospital, and The Parker Institute, Department of Rheumatology, Bispebjerg and Frederiksberg Hospital, the Capital Region of Copenhagen M C Kapetanovic, MD, PhD, Department of Clinical Sciences Lund
    J Rheumatol 43:1017-23. 2016
    ....
  20. pmc Prevalence and incidence of gout in southern Sweden from the socioeconomic perspective
    Meliha C Kapetanovic
    Department of Clinical Sciences, Lund, Section for Rheumatology, Lund University, Lund and Skåne University Hospital, Section for Rheumatology in Lund and Malmö, Lund, Sweden
    RMD Open 2:e000326. 2016
    ..To estimate the prevalence and cumulative incidence of gout in southern Sweden with respect to socioeconomic status...
  21. ncbi Fibronectin fragments cause release and degradation of collagen-binding molecules from equine explant cultures
    Anna Johnson
    Department of Cell and Molecular Biology, Section for Connective Tissue Biology, Lund University, Lund, Sweden
    Osteoarthritis Cartilage 12:149-59. 2004
    ..In this study we investigated the fate of the collagen- and cell-binding molecules Cartilage oligomeric matrix protein (COMP) and chondroadherin...
  22. ncbi Treatment with tumor necrosis factor blockers is associated with a lower incidence of first cardiovascular events in patients with rheumatoid arthritis
    Lennart T H Jacobsson
    Department of Rheumatology, Malmo University Hospital, Malmo, Sweden
    J Rheumatol 32:1213-8. 2005
    ..To investigate the risk of cardiovascular disease (CVD) in patients with rheumatoid arthritis (RA) treated with tumor necrosis factor (TNF) inhibitors, compared to a standard RA population...
  23. pmc Circulating complexes between tumour necrosis factor-alpha and etanercept predict long-term efficacy of etanercept in juvenile idiopathic arthritis
    Robin Kahn
    Department of Pediatrics, Clinical Sciences Lund, Lund University and Skåne University Hospital, Lund, Sweden
    Acta Paediatr 105:427-32. 2016
    ..We studied whether serum levels of TNF-α, free or bound to etanercept, could predict long-term efficacy of etanercept in children with JIA...
  24. ncbi Prediction of mortality in rheumatoid arthritis based on disease activity markers
    Christina Book
    Department of Rheumatology, Malmo University Hospital, S 205 02 Malmo, Sweden
    J Rheumatol 32:430-4. 2005
    ..The risks and predictors for mortality in patients with rheumatoid arthritis (RA) were examined in a cohort of 152 consecutive outpatients (119 women, 33 men) seen in a 2 month period...