- Higher occurrence of childhood cancer in families with germline mutations in BRCA2, MMR and CDKN2A genesSusanne Magnusson
Department of Oncology, Institution of Clinical Sciences, Lund University, Lund University Hospital, Lund, 22185, Sweden
Fam Cancer 7:331-7. 2008..4; 95% CI 3.5-44.1), MMR genes (OR 29.0; 95% CI 9.1-92.6), and CDKN2A (OR 30.2; 95% CI 7.0-131.1). This study suggests that the risk for childhood tumors is increased in families with germline mutations in the BRCA2, MMR and CDKN2A genes...
- Prevalence of germline TP53 mutations and history of Li-Fraumeni syndrome in families with childhood adrenocortical tumors, choroid plexus tumors, and rhabdomyosarcoma: a population-based surveySusanne Magnusson
Department of Oncology, Clinical Sciences, Lund University, Lund, Sweden
Pediatr Blood Cancer 59:846-53. 2012..In this study, we evaluated the frequency of germline TP53 mutations and family history in a population-based series of patients...
- Increased incidence of childhood, prostate and breast cancers in relatives of childhood cancer patientsSusanne Magnusson
Department of Oncology, Clinical Sciences, Lund University, Barngatan 2B, 22185, Lund, Sweden
Fam Cancer 11:145-55. 2012..Studying extended families with multiple childhood tumors may be a valuable approach to understanding the etiology of childhood tumors...