L Stefan Lohmander

Summary

Affiliation: Lund University Hospital
Country: Sweden

Publications

  1. ncbi Longitudinal and cross-sectional variability in markers of joint metabolism in patients with knee pain and articular cartilage abnormalities
    L S Lohmander
    Department of Orthopedics, Lund University Hospital, Sweden
    Osteoarthritis Cartilage 6:351-61. 1998
  2. pmc Patient relevant outcomes after total hip replacement. A comparison between different surgical techniques
    Anna K Nilsdotter
    Spenshult Hospital of Rheumatic Diseases, Halmstad, Sweden
    Health Qual Life Outcomes 1:21. 2003
  3. pmc Revision and complication rates in 654 Exeter total hip replacements, with a maximum follow-up of 20 years
    Jonas Franklin
    Department of Orthopedics, Central Hospital, 600 Akureyri, Iceland
    BMC Musculoskelet Disord 4:6. 2003
  4. pmc A randomised, placebo controlled, comparative trial of the gastrointestinal safety and efficacy of AZD3582 versus naproxen in osteoarthritis
    L S Lohmander
    Department of Orthopaedics, Lund University, SE 221 85 Lund, Sweden
    Ann Rheum Dis 64:449-56. 2005
  5. ncbi Markers of altered metabolism in osteoarthritis
    L Stefan Lohmander
    Department of Orthopaedics, Lund University Hospital, Lund, Sweden
    J Rheumatol Suppl 70:28-35. 2004
  6. ncbi The release of crosslinked peptides from type II collagen into human synovial fluid is increased soon after joint injury and in osteoarthritis
    L Stefan Lohmander
    Lund University Hospital, Lund, Sweden
    Arthritis Rheum 48:3130-9. 2003
  7. ncbi [Osteoarthritis is frequent, very frequent. What can we do?]
    Stefan Lohmander
    Avdelningen för ortopedi, institutionen för rörelseorganens sjukdomar, Universitetssjukhuset, Lund
    Lakartidningen 99:4342-4. 2002
  8. ncbi [Research, progress and controversies around osteoarthritis]
    Stefan Lohmander
    Avdelningen för ortopedi, institutionen för rörelseorganens sjukdomar, Universitetssjukhuset, Lund
    Lakartidningen 99:4720-2. 2002
  9. ncbi [Many paths converge in arthritis. Awareness of risk factors and illness mechanisms increase steadily]
    Stefan Lohmander
    Avdelningen för ortopedi, institutionen för rörelseorganens sjukdomar, Universitetssjukhuset, Lund
    Lakartidningen 99:4480-3. 2002
  10. ncbi ["Sham" surgery. A study from the USA shows that placebo surgery is as good as arthroscopic debridement and lavage]
    Stefan Lohmander
    Avdelningen för ortopedi, institutionen för rörelseorganens sjukdomar, Universitetssjukhuset i Lund
    Lakartidningen 99:3926-9. 2002

Detail Information

Publications67

  1. ncbi Longitudinal and cross-sectional variability in markers of joint metabolism in patients with knee pain and articular cartilage abnormalities
    L S Lohmander
    Department of Orthopedics, Lund University Hospital, Sweden
    Osteoarthritis Cartilage 6:351-61. 1998
    ....
  2. pmc Patient relevant outcomes after total hip replacement. A comparison between different surgical techniques
    Anna K Nilsdotter
    Spenshult Hospital of Rheumatic Diseases, Halmstad, Sweden
    Health Qual Life Outcomes 1:21. 2003
    ..To investigate differences in pre- and postoperative patient-relevant outcome between hybrid total hip replacement (THR) and cemented THR in patients with primary osteoarthritis (OA)...
  3. pmc Revision and complication rates in 654 Exeter total hip replacements, with a maximum follow-up of 20 years
    Jonas Franklin
    Department of Orthopedics, Central Hospital, 600 Akureyri, Iceland
    BMC Musculoskelet Disord 4:6. 2003
    ..Total hip replacements (THR) have been done at FSA Central Hospital in Akureyri, Iceland since 1982 with the Exeter hip implant being in use from the beginning...
  4. pmc A randomised, placebo controlled, comparative trial of the gastrointestinal safety and efficacy of AZD3582 versus naproxen in osteoarthritis
    L S Lohmander
    Department of Orthopaedics, Lund University, SE 221 85 Lund, Sweden
    Ann Rheum Dis 64:449-56. 2005
    ..To evaluate the gastrointestinal safety and efficacy of the COX inhibiting nitric oxide donator AZD3582 in patients with hip or knee osteoarthritis...
  5. ncbi Markers of altered metabolism in osteoarthritis
    L Stefan Lohmander
    Department of Orthopaedics, Lund University Hospital, Lund, Sweden
    J Rheumatol Suppl 70:28-35. 2004
  6. ncbi The release of crosslinked peptides from type II collagen into human synovial fluid is increased soon after joint injury and in osteoarthritis
    L Stefan Lohmander
    Lund University Hospital, Lund, Sweden
    Arthritis Rheum 48:3130-9. 2003
    ..To determine concentrations of crosslinked C-telopeptide fragments of type II collagen (CTX-II) in synovial fluid (SF) from patients with joint injury, osteoarthritis (OA), or other knee arthritides...
  7. ncbi [Osteoarthritis is frequent, very frequent. What can we do?]
    Stefan Lohmander
    Avdelningen för ortopedi, institutionen för rörelseorganens sjukdomar, Universitetssjukhuset, Lund
    Lakartidningen 99:4342-4. 2002
  8. ncbi [Research, progress and controversies around osteoarthritis]
    Stefan Lohmander
    Avdelningen för ortopedi, institutionen för rörelseorganens sjukdomar, Universitetssjukhuset, Lund
    Lakartidningen 99:4720-2. 2002
  9. ncbi [Many paths converge in arthritis. Awareness of risk factors and illness mechanisms increase steadily]
    Stefan Lohmander
    Avdelningen för ortopedi, institutionen för rörelseorganens sjukdomar, Universitetssjukhuset, Lund
    Lakartidningen 99:4480-3. 2002
    ..Increased occupational joint load, joint injuries and obesity are well recognized risk factors for osteoarthritis...
  10. ncbi ["Sham" surgery. A study from the USA shows that placebo surgery is as good as arthroscopic debridement and lavage]
    Stefan Lohmander
    Avdelningen för ortopedi, institutionen för rörelseorganens sjukdomar, Universitetssjukhuset i Lund
    Lakartidningen 99:3926-9. 2002
  11. pmc What can we do about osteoarthritis?
    L S Lohmander
    Department of Orthopedics, University Hospital, Lund, Sweden
    Arthritis Res 2:95-100. 2000
    ..Will saving the cartilage improve patient pain and function? Effective outcome measures are needed to accelerate testing of new treatments. Further improvement is needed in joint implant technology to decrease costs, wear and loosening...
  12. pmc Knee complaints vary with age and gender in the adult population. Population-based reference data for the Knee injury and Osteoarthritis Outcome Score (KOOS)
    Przemyslaw T Paradowski
    Department of Orthopedics, Clinical Sciences, Lund University Hospital, SE 221 85 Lund, Sweden
    BMC Musculoskelet Disord 7:38. 2006
    ....
  13. pmc The effect of patient characteristics on variability in pain and function over two years in early knee osteoarthritis
    Przemyslaw T Paradowski
    Department of Orthopedics, Lund University, Lund University Hospital, SE 221 85 Lund, Sweden
    Health Qual Life Outcomes 3:59. 2005
    ..The objective of this study was to investigate the influence of age, gender, and body mass index (BMI) on clinically relevant change in pain and function over two years in subjects at high risk for or with knee OA...
  14. ncbi Long-term outcome of meniscectomy: symptoms, function, and performance tests in patients with or without radiographic osteoarthritis compared to matched controls
    E M Roos
    Institute of Musculoskeletal Disease, Department of Orthopedics, Lund University, Sweden
    Osteoarthritis Cartilage 9:316-24. 2001
    ..To describe the long-term influence of meniscectomy on pain, functional limitations, and muscular performance. To assess the effects of radiographic osteoarthritis (OA), gender and age on these outcomes in patients with meniscectomy...
  15. pmc Treatment for acute anterior cruciate ligament tear: five year outcome of randomised trial
    Richard B Frobell
    Department of Orthopaedics, Clinical Sciences Lund, Lund University, SE 22185 Lund, Sweden
    BMJ 346:f232. 2013
    ....
  16. ncbi The long-term consequence of anterior cruciate ligament and meniscus injuries: osteoarthritis
    L Stefan Lohmander
    Department of Orthopaedics, Clinical Sciences Lund, Lund University, Lund, Sweden
    Am J Sports Med 35:1756-69. 2007
    ....
  17. doi Incidence of severe knee and hip osteoarthritis in relation to different measures of body mass: a population-based prospective cohort study
    L S Lohmander
    Department of Orthopedics, Clinical Sciences Lund, Lund University, Lund, Sweden
    Ann Rheum Dis 68:490-6. 2009
    ..To determine in a prospective population-based cohort study relationships between different measures of body mass and the incidence of severe knee and hip osteoarthritis defined as arthroplasty of knee or hip due to osteoarthritis...
  18. ncbi Change in self-reported outcomes and objective physical function over 7 years in middle-aged subjects with or at high risk of knee osteoarthritis
    E M Roos
    Department of Orthopedics, Clinical Sciences Lund, Lund University, Sweden
    Ann Rheum Dis 67:505-10. 2008
    ..In the present work, we describe the clinical course and predictors of change in self-reported outcomes and objectively assessed physical function over time in middle-aged subjects at high risk of, or with knee osteoarthritis (OA)...
  19. ncbi Estimation of the identity of proteolytic aggrecan fragments using PAGE migration and Western immunoblot
    A Struglics
    Department of Clinical Sciences, Orthopaedics, Lund University, Lund, Sweden
    Osteoarthritis Cartilage 14:898-905. 2006
    ..To develop calculation models, using Western immunoblot, as a tool for the estimation of proteolytic human aggrecan fragment identity...
  20. doi The acutely ACL injured knee assessed by MRI: are large volume traumatic bone marrow lesions a sign of severe compression injury?
    R B Frobell
    Department of Orthopedics, Clinical Sciences Lund, Lund University, Lund, Sweden
    Osteoarthritis Cartilage 16:829-36. 2008
    ..To relate BML location and volume to cortical depression fractures, meniscal injuries and patient characteristics...
  21. doi Western blot quantification of aggrecan fragments in human synovial fluid indicates differences in fragment patterns between joint diseases
    A Struglics
    Department of Orthopaedics, Clinical Sciences Lund, Lund University, Sweden
    Osteoarthritis Cartilage 17:497-506. 2009
    ..To develop a Western blot method for quantification of multiple aggrecan fragments in human synovial fluids (SFs)...
  22. doi Sex differences in the association between body mass index and total hip or knee joint replacement resulting from osteoarthritis
    J Franklin
    Department of Orthopaedics, Clinical Sciences Lund, Lund University, Sweden
    Ann Rheum Dis 68:536-40. 2009
    ..To examine the association between body mass index (BMI) and osteoarthritis (OA) leading to total hip (THR) or knee (TKR) joint replacement...
  23. doi The acutely ACL injured knee assessed by MRI: changes in joint fluid, bone marrow lesions, and cartilage during the first year
    R B Frobell
    Department of Orthopedics, Clinical Sciences Lund, Lund University, Lund, Sweden
    Osteoarthritis Cartilage 17:161-7. 2009
    ..To identify factors associated with these changes...
  24. pmc Synovial fluid level of aggrecan ARGS fragments is a more sensitive marker of joint disease than glycosaminoglycan or aggrecan levels: a cross-sectional study
    Staffan Larsson
    Department of Orthopaedics, Clinical Sciences Lund, Lund University, SE 221 85 Lund, Sweden
    Arthritis Res Ther 11:R92. 2009
    ....
  25. pmc Association between synovial fluid levels of aggrecan ARGS fragments and radiographic progression in knee osteoarthritis
    Staffan Larsson
    Department of Orthopedics, Clinical Sciences Lund, Lund University, BMC C12, Klinikgatan 28, SE 221 84 Lund, Sweden
    Arthritis Res Ther 12:R230. 2010
    ..We determined whether synovial fluid (SF) levels of ARGS-aggrecan distinguish subjects with progressive radiographic knee osteoarthritis (ROA) from those with stable or no ROA...
  26. pmc Similar group mean scores, but large individual variations, in patient-relevant outcomes over 2 years in meniscectomized subjects with and without radiographic knee osteoarthritis
    Przemyslaw T Paradowski
    Department of Orthopedics, Lund University Hospital, SE 221 85 Lund, Sweden
    Health Qual Life Outcomes 2:38. 2004
    ..The aim of the study was, thus, to assess the variation in pain and function on group and individual level over 2 years in previously meniscectomized individuals with and without radiographic knee osteoarthritis (OA)...
  27. ncbi Substantial disability 3 months after arthroscopic partial meniscectomy: A prospective study of patient-relevant outcomes
    E M Roos
    Departments of Physical Therapy and Orthopaedics, Lund University, Lund, Sweden
    Arthroscopy 16:619-26. 2000
    ..We further suggest that preoperative information for the meniscectomy patient should include a realistic expected functional outcome...
  28. pmc Radiographic stage of osteoarthritis or sex of the patient does not predict one year outcome after total hip arthroplasty
    A K Nilsdotter
    Department of Orthopaedics, Halmstad County Hospital, Sweden
    Ann Rheum Dis 60:228-32. 2001
    ..To investigate sex related differences in preoperative radiographic and self reported status and in postoperative outcome...
  29. ncbi Human osteoarthritis synovial fluid and joint cartilage contain both aggrecanase- and matrix metalloproteinase-generated aggrecan fragments
    A Struglics
    Department of Orthopaedics, Lund University, Lund, Sweden
    Osteoarthritis Cartilage 14:101-13. 2006
    ..To identify the major aggrecanase- and matrix metalloproteinase (MMP)-generated aggrecan fragments in human osteoarthritis (OA) synovial fluid and in human OA joint cartilage...
  30. pmc Predictors of patient relevant outcome after total hip replacement for osteoarthritis: a prospective study
    A K Nilsdotter
    Department of Orthopaedics, Lund University Hospital, Spenshult Hospital of Rheumatic Diseases, Halmstad, Sweden
    Ann Rheum Dis 62:923-30. 2003
    ..To investigate prospectively long term patient relevant outcomes after unilateral total hip replacement (THR) for osteoarthritis (OA). To identify non-responders to this intervention and patient related predictors of unsatisfactory outcome...
  31. pmc Patellofemoral osteoarthritis coexistent with tibiofemoral osteoarthritis in a meniscectomy population
    M Englund
    Department of Orthopaedics, Lund University Hospital, SE 221 85 Lund, Sweden
    Ann Rheum Dis 64:1721-6. 2005
    ..To evaluate the frequency of patellofemoral osteoarthritis and its relevance to symptoms and function in a meniscectomy population...
  32. ncbi Patient-relevant outcomes fourteen years after meniscectomy: influence of type of meniscal tear and size of resection
    M Englund
    Department of Orthopedics, Lund University Hospital, S-221 85, Sweden
    Rheumatology (Oxford) 40:631-9. 2001
    ....
  33. ncbi Risk factors for symptomatic knee osteoarthritis fifteen to twenty-two years after meniscectomy
    M Englund
    Lund University, Lund, Sweden
    Arthritis Rheum 50:2811-9. 2004
    ....
  34. doi Treatment for acute anterior cruciate ligament tear: five year outcome of randomised trial
    Richard B Frobell
    Department of Orthopaedics, Clinical Sciences Lund, Lund University, Sweden
    Br J Sports Med 49:700. 2015
    ..ACL) rupture, do patient reported or radiographic outcomes after five years differ between those treated with rehabilitation plus early ACL reconstruction and those treated with rehabilitation and optional delayed ACL reconstruction?..
  35. doi Aggrecanase cleavage in juvenile idiopathic arthritis patients is minimally detected in the aggrecan interglobular domain but robust at the aggrecan C-terminus
    André Struglics
    Lund University, Lund, Sweden
    Arthritis Rheum 64:4151-61; author reply 4162-3. 2012
    ..To investigate aggrecan degradation in juvenile idiopathic arthritis (JIA)...
  36. doi A randomized trial of treatment for acute anterior cruciate ligament tears
    Richard B Frobell
    Department of Orthopedics, Clinical Sciences Lund, Lund University, Lund, Sweden
    N Engl J Med 363:331-42. 2010
    ..The optimal management of a torn anterior cruciate ligament (ACL) of the knee is unknown...
  37. pmc The Knee injury and Osteoarthritis Outcome Score (KOOS): from joint injury to osteoarthritis
    Ewa M Roos
    Department of Orthopaedics, Lund University Hospital, SE 221 85 Lund, Sweden
    Health Qual Life Outcomes 1:64. 2003
    ..The measure is relatively new and further use of the instrument will add knowledge and suggest areas that need to be further explored and improved...
  38. ncbi Comparative responsiveness of measures of pain and function after total hip replacement
    A K Nilsdotter
    Department of Orthopedics, Halmstad County Hospital, Sweden
    Arthritis Rheum 45:258-62. 2001
    ..CONCLUSION: Self-administered questionnaires like WOMAC and SF-36 are more responsive measures of pain and function than range of motion, performance tests, and observer-administered questions (FAS) following total hip replacement...
  39. ncbi Impact of type of meniscal tear on radiographic and symptomatic knee osteoarthritis: a sixteen-year followup of meniscectomy with matched controls
    M Englund
    Department of Orthopedics, Lund University Hospital, SE 221 85 Lund, Sweden
    Arthritis Rheum 48:2178-87. 2003
    ..To investigate long-term radiographic and patient-relevant outcome of isolated limited meniscectomy with regard to type of meniscal tear and extent of surgical resection...
  40. doi C-reactive protein, metabolic syndrome and incidence of severe hip and knee osteoarthritis. A population-based cohort study
    G Engstrom
    AstraZeneca R and D, Lund, Sweden
    Osteoarthritis Cartilage 17:168-73. 2009
    ..To explore the relationships between C-reactive protein (CRP), metabolic syndrome (MetS) and incidence of severe knee or hip osteoarthritis (OA) in a prospective study...
  41. ncbi Association of radiographic hand osteoarthritis with radiographic knee osteoarthritis after meniscectomy
    M Englund
    Lund University Hospital, Lund, Sweden
    Arthritis Rheum 50:469-75. 2004
    ..To evaluate the association between radiographic hand osteoarthritis (OA), a disease with marked heredity, and radiographic knee OA in patients treated with meniscectomy...
  42. ncbi Age and waiting time as predictors of outcome after total hip replacement for osteoarthritis
    A K Nilsdotter
    Department of Orthopedics, Halmstad County Hospital, Halmstad, Sweden
    Rheumatology (Oxford) 41:1261-7. 2002
    ..To investigate in a prospective study the relationship between age, pre-operative status, waiting time and post-operative outcome in patients assigned for unilateral total hip replacement (THR) due to osteoarthritis (OA)...
  43. ncbi High prevalence of knee osteoarthritis, pain, and functional limitations in female soccer players twelve years after anterior cruciate ligament injury
    L S Lohmander
    Lund University, Lund, Sweden
    Arthritis Rheum 50:3145-52. 2004
    ..To determine the prevalence of radiographic knee osteoarthritis (OA) as well as knee-related symptoms and functional limitations in female soccer players 12 years after an anterior cruciate ligament (ACL) injury...
  44. pmc Effect of leisure time physical activity on severe knee or hip osteoarthritis leading to total joint replacement: a population-based prospective cohort study
    Eva Ageberg
    Department of Orthopedics, Clinical Sciences Lund, Lund University, Lund, Sweden
    BMC Musculoskelet Disord 13:73. 2012
    ..The aim was to explore in a prospective population-based cohort study the influence of leisure time physical activity on severe knee or hip OA, defined as knee or hip replacement due to OA...
  45. ncbi Tissue engineering of cartilage: do we need it, can we do it, is it good and can we prove it?
    L Stefan Lohmander
    Department of Orthopedics, University Hospital Lund, SE 22185 Lund, Sweden
    Novartis Found Symp 249:2-10; discussion 10-6, 170-4, 239-41. 2003
    ..The relationship between these outcome dimensions is unclear. However, the outcome as judged by the patient using standardized measures is the gold standard...
  46. ncbi Clinical update: treating osteoarthritis
    L Stefan Lohmander
    Department of Orthopaedics, Clinical Sciences Lund, Lund University, SE 22185 Lund, Sweden
    Lancet 370:2082-4. 2007
  47. ncbi Can we identify a 'high risk' patient profile to determine who will experience rapid progression of osteoarthritis?
    L Stefan Lohmander
    Department of Orthopaedics, Lund University Hospital, Lund University, SE 22185 Lund, Sweden
    Osteoarthritis Cartilage 12:S49-52. 2004
    ..Further evaluation of these variables and their individual and combined influence will be useful to design a risk profile for OA incidence and progression...
  48. ncbi The challenge of recruiting patients with anterior cruciate ligament injury of the knee into a randomized clinical trial comparing surgical and non-surgical treatment
    Richard B Frobell
    Department of Orthopedics, Clinical Sciences, Lund University Hospital, 221 85 Lund, Sweden
    Contemp Clin Trials 28:295-302. 2007
    ....
  49. doi No economic benefit of early knee reconstruction over optional delayed reconstruction for ACL tears: registry enriched randomised controlled trial data
    Aliasghar A Kiadaliri
    Clinical Epidemiology Unit, Orthopaedics, Department of Clinical Sciences Lund, Lund University, Lund, Sweden Health Services Management Research Center, Institute for Futures Studies in Health, Kerman University of Medical Sciences, Kerman, Iran
    Br J Sports Med 50:558-63. 2016
    ..To analyse 5-year cost-effectiveness of early versus optional delayed acute anterior cruciate ligament (ACL) reconstruction...
  50. pmc Association of knee pain and different definitions of knee osteoarthritis with health-related quality of life: a population-based cohort study in southern Sweden
    Aliasghar A Kiadaliri
    Clinical Epidemiology Unit, Orthopaedics, Department of Clinical Sciences Lund, Lund University, Lund, Sweden
    Health Qual Life Outcomes 14:121. 2016
    ..The main aim of this study was to measure and compare the impact of knee OA and its different definitions on HRQoL in the general population...
  51. doi Prevalence of knee pain and knee OA in southern Sweden and the proportion that seeks medical care
    Aleksandra Turkiewicz
    Department of Orthopaedics, Clinical Sciences Lund, Lund University, Epidemiology and Register Centre South, Skane University Hospital, Lund, Astra Zeneca R and D Mölndal, Molndal, Cardiovascular Epidemiology, Clinical Sciences Malmö, Lund University, Department of Clinical Sciences, Skane University Hospital, Malmo, Research Unit for Musculoskeletal Function and Physiotherapy, Department of Orthopedics and Traumatology, University of Southern Denmark, Odense, Denmark and Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MA, USA Department of Orthopaedics, Clinical Sciences Lund, Lund University, Epidemiology and Register Centre South, Skane University Hospital, Lund, Astra Zeneca R and D Mölndal, Molndal, Cardiovascular Epidemiology, Clinical Sciences Malmö, Lund University, Department of Clinical Sciences, Skane University Hospital, Malmo, Research Unit for Musculoskeletal Function and Physiotherapy, Department of Orthopedics and Traumatology, University of Southern Denmark, Odense, Denmark and Clinical Epidemiology Research and Training Unit, Germany
    Rheumatology (Oxford) 54:827-35. 2015
    ..The aim of this study was to estimate the prevalence of frequent knee pain in radiographic, symptomatic and clinically defined knee OA in middle-aged and elderly patients and the proportion that seeks medical care...
  52. ncbi Standardized incidence rates of total hip replacement for primary hip osteoarthritis in the 5 Nordic countries: similarities and differences
    L Stefan Lohmander
    Department of Orthopaedics, Lund University, Sweden
    Acta Orthop 77:733-40. 2006
    ....
  53. ncbi Use of the plasma stromelysin (matrix metalloproteinase 3) concentration to predict joint space narrowing in knee osteoarthritis
    L Stefan Lohmander
    Lund University, Lund, Sweden
    Arthritis Rheum 52:3160-7. 2005
    ..To determine whether baseline or serial plasma concentrations of stromelysin (matrix metalloproteinase 3 [MMP-3]) protein might distinguish subjects with progressive radiographic knee osteoarthritis (OA) from those with stable disease...
  54. doi The meniscus in knee osteoarthritis
    Martin Englund
    Musculoskeletal Sciences, Department of Orthopedics, Klinikgatan 22, Lund University Hospital, SE 221 85 Lund, Sweden
    Rheum Dis Clin North Am 35:579-90. 2009
    ..A degenerative meniscal lesion often suggests early-stage knee OA. Surgical resection of nonobstructive degenerate lesions may merely remove evidence of the disorder while the OA and associated symptoms proceed...
  55. ncbi Structure and synthesis of intracellular proteoglycan in HL-60 human leukemic promyelocytes
    L S Lohmander
    Department of Orthopedics, University Hospital, Lund, Sweden
    J Biol Chem 265:5802-8. 1990
    ..L., Avraham, S., Gartner, M.C., Bruns, G.A., Austen, K.E., and Weis, J.H. (1988) J. Biol. Chem. 263, 7287-7291)...
  56. ncbi Acute rotational trauma to the knee: poor agreement between clinical assessment and magnetic resonance imaging findings
    R B Frobell
    Department of Clinical Sciences, Orthopaedics, Lund University, Lund, Sweden
    Scand J Med Sci Sports 17:109-14. 2007
    ....
  57. pmc The complement system is activated in synovial fluid from subjects with knee injury and from patients with osteoarthritis
    André Struglics
    Department of Clinical Sciences Lund, Orthopaedics, Lund University, Faculty of Medicine, BMC C12, SE 221 84, Lund, Sweden
    Arthritis Res Ther 18:223. 2016
    ..The association between complement factors, cytokines and OA has not been investigated. The aim of the present study was to explore the involvement of the complement system after knee trauma and in OA...
  58. doi Changes in Cytokines and Aggrecan ARGS Neoepitope in Synovial Fluid and Serum and in C-Terminal Crosslinking Telopeptide of Type II Collagen and N-Terminal Crosslinking Telopeptide of Type I Collagen in Urine Over Five Years After Anterior Cruciate Ligame
    André Struglics
    Lund University, Lund, Sweden
    Arthritis Rheumatol 67:1816-25. 2015
    ....
  59. pmc High tibial osteotomy in Sweden, 1998-2007: a population-based study of the use and rate of revision to knee arthroplasty
    Annette W-Dahl
    Department of Orthopedics, Clinical Sciences Lund, Lund University, Lund, Sweden
    Acta Orthop 83:244-8. 2012
    ..We evaluated the use and outcome-expressed as rate of revision to knee arthroplasty-of HTO performed in Sweden with 9 million inhabitants, 1998-2007...
  60. doi Human aggrecanase generated synovial fluid fragment levels are elevated directly after knee injuries due to proteolysis both in the inter globular and chondroitin sulfate domains
    A Struglics
    Department of Orthopaedics, Clinical Sciences Lund, Lund University, Lund, Sweden
    Osteoarthritis Cartilage 19:1047-57. 2011
    ..To examine different aggrecanase generated fragments in synovial fluid (SF) from patients with acute and chronic knee injuries and from knee healthy subjects...
  61. ncbi Comparison of two hyaluronan drugs and placebo in patients with knee osteoarthritis. A controlled, randomized, double-blind, parallel-design multicentre study
    J Karlsson
    Department of Orthopaedics, Sahlgrenska University Hospital Ostra, Goteborg, Sweden
    Rheumatology (Oxford) 41:1240-8. 2002
    ..To compare the efficacy and safety of intra-articular injections of two different hyaluronan preparations and placebo in patients with knee osteoarthritis...
  62. doi Natural history of radiographic features of hand osteoarthritis over 10 years
    P T Paradowski
    Department of Orthopedics, Orthopedic Center in Ostergotland, Vrinnevi Hospital, Norrkoping, Sweden
    Osteoarthritis Cartilage 18:917-22. 2010
    ..To evaluate the natural history of radiographic hand osteoarthritis (OA) over 10 years...
  63. doi Intraarticular sprifermin (recombinant human fibroblast growth factor 18) in knee osteoarthritis: a randomized, double-blind, placebo-controlled trial
    L Stefan Lohmander
    Lund University, Lund, Sweden University of Southern Denmark, Odense, Denmark
    Arthritis Rheumatol 66:1820-31. 2014
    ..To evaluate the efficacy and safety of intraarticular sprifermin (recombinant human fibroblast growth factor 18) in the treatment of symptomatic knee osteoarthritis (OA)...
  64. pmc Hip disability and osteoarthritis outcome score (HOOS)--validity and responsiveness in total hip replacement
    Anna K Nilsdotter
    Department of Orthopedics, Lund University Hospital, Sweden
    BMC Musculoskelet Disord 4:10. 2003
    ..0)...
  65. pmc Association between occupation and knee and hip replacement due to osteoarthritis: a case-control study
    Jonas Franklin
    Department of Orthopedics, University Hospital, Eyrarlandsvegi, Akureyri, IS 600, Iceland
    Arthritis Res Ther 12:R102. 2010
    ..The objective of this study was to examine the association between occupation and osteoarthritis (OA) leading to total knee (TKR) or hip (THR) joint replacement...
  66. ncbi OMERACT/OARSI initiative to define states of severity and indication for joint replacement in hip and knee osteoarthritis
    Laure Gossec
    Medicine Faculty, Paris 5 René Descartes University AP HP, Cochin Hospital, Department of Rheumatology B, Paris, France
    J Rheumatol 34:1432-5. 2007
    ..quot;..
  67. ncbi Pathogenesis and management of pain in osteoarthritis
    Paul A Dieppe
    MRC Health Services Research Collaboration, Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, UK
    Lancet 365:965-73. 2005
    ..Central pain sensitisation can also occur, and psychosocial factors are important determinants of pain severity. We present a stepwise approach to the management of osteoarthritis...