Weili Xu

Summary

Affiliation: Karolinska Institutet
Country: Sweden

Publications

  1. ncbi request reprint The effect of borderline diabetes on the risk of dementia and Alzheimer's disease
    Weili Xu
    Aging Research Center, Karolinska Institutet, Stockholm, Sweden
    Diabetes 56:211-6. 2007
  2. doi request reprint Accelerated progression from mild cognitive impairment to dementia among APOE ε4ε4 carriers
    Wei Li Xu
    Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden
    J Alzheimers Dis 33:507-15. 2013
  3. pmc Midlife overweight and obesity increase late-life dementia risk: a population-based twin study
    W L Xu
    Aging Research Center, Karolinska Institutet, Gavlegatan 16, S 113 30 Stockholm, Sweden
    Neurology 76:1568-74. 2011
  4. pmc Accelerated progression from mild cognitive impairment to dementia in people with diabetes
    Weili Xu
    Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden
    Diabetes 59:2928-35. 2010
  5. doi request reprint Uncontrolled diabetes increases the risk of Alzheimer's disease: a population-based cohort study
    W L Xu
    Department of Neurobiology, Aging Research Center, Care Sciences and Society, Stockholm Gerontology Research Center, Karolinska Institutet, Stockholm, Sweden
    Diabetologia 52:1031-9. 2009
  6. pmc Mid- and late-life diabetes in relation to the risk of dementia: a population-based twin study
    Weili Xu
    Department of Neurobiology, Care Sciences and Society, Aging Research Center, Karolinska Institutet and Stockholm Gerontology Research Center, Stockholm, Sweden
    Diabetes 58:71-7. 2009
  7. pmc Relationship of subjective cognitive impairment and cognitive impairment no dementia to chronic disease and multimorbidity in a nation-wide twin study
    Barbara Caracciolo
    Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden
    J Alzheimers Dis 36:275-84. 2013
  8. pmc Differential distribution of subjective and objective cognitive impairment in the population: a nation-wide twin-study
    Barbara Caracciolo
    Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden
    J Alzheimers Dis 29:393-403. 2012
  9. doi request reprint Vascular risk profiles for dementia and Alzheimer's disease in very old people: a population-based longitudinal study
    Chengxuan Qiu
    Aging Research Center, Department of Neurobiology, Karolinska Institutet, Stockholm University, Stockholm, Sweden
    J Alzheimers Dis 20:293-300. 2010
  10. doi request reprint The obesity related gene, FTO, interacts with APOE, and is associated with Alzheimer's disease risk: a prospective cohort study
    Lina Keller
    Aging Research Center, Department NVS, Karolinska Institutet and Stockholm University, Stockholm, Sweden
    J Alzheimers Dis 23:461-9. 2011

Detail Information

Publications23

  1. ncbi request reprint The effect of borderline diabetes on the risk of dementia and Alzheimer's disease
    Weili Xu
    Aging Research Center, Karolinska Institutet, Stockholm, Sweden
    Diabetes 56:211-6. 2007
    ..Borderline diabetes may interact with severe systolic hypertension to multiply the risk of Alzheimer's disease...
  2. doi request reprint Accelerated progression from mild cognitive impairment to dementia among APOE ε4ε4 carriers
    Wei Li Xu
    Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden
    J Alzheimers Dis 33:507-15. 2013
    ..The ε4 homozygote substantially accelerates progression from MCI to dementia, and anticipate dementia occurrence by more than 3 years in people with MCI...
  3. pmc Midlife overweight and obesity increase late-life dementia risk: a population-based twin study
    W L Xu
    Aging Research Center, Karolinska Institutet, Gavlegatan 16, S 113 30 Stockholm, Sweden
    Neurology 76:1568-74. 2011
    ....
  4. pmc Accelerated progression from mild cognitive impairment to dementia in people with diabetes
    Weili Xu
    Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden
    Diabetes 59:2928-35. 2010
    ..We sought to examine whether diabetes and pre-diabetes are associated with MCI and accelerate the progression from MCI to dementia...
  5. doi request reprint Uncontrolled diabetes increases the risk of Alzheimer's disease: a population-based cohort study
    W L Xu
    Department of Neurobiology, Aging Research Center, Care Sciences and Society, Stockholm Gerontology Research Center, Karolinska Institutet, Stockholm, Sweden
    Diabetologia 52:1031-9. 2009
    ..We aimed to clarify the association of diabetes with different dementing disorders taking into account glycaemic control, and to explore the link between glucose dysregulation and neurodegeneration...
  6. pmc Mid- and late-life diabetes in relation to the risk of dementia: a population-based twin study
    Weili Xu
    Department of Neurobiology, Care Sciences and Society, Aging Research Center, Karolinska Institutet and Stockholm Gerontology Research Center, Stockholm, Sweden
    Diabetes 58:71-7. 2009
    ..We aimed to verify the association between diabetes and the risk of dementia, Alzheimer's disease, and vascular dementia in twins and to explore whether genetic and early-life environmental factors could contribute to this association...
  7. pmc Relationship of subjective cognitive impairment and cognitive impairment no dementia to chronic disease and multimorbidity in a nation-wide twin study
    Barbara Caracciolo
    Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden
    J Alzheimers Dis 36:275-84. 2013
    ..The association is stronger when diseases co-occur, especially for SCI. Genetic and early-life environmental factors may partially explain the association of CIND but not that of SCI with chronic diseases...
  8. pmc Differential distribution of subjective and objective cognitive impairment in the population: a nation-wide twin-study
    Barbara Caracciolo
    Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden
    J Alzheimers Dis 29:393-403. 2012
    ..Shared environmental influences rather than genetic background play a role in the occurrence of SCI and CIND...
  9. doi request reprint Vascular risk profiles for dementia and Alzheimer's disease in very old people: a population-based longitudinal study
    Chengxuan Qiu
    Aging Research Center, Department of Neurobiology, Karolinska Institutet, Stockholm University, Stockholm, Sweden
    J Alzheimers Dis 20:293-300. 2010
    ..Severe cerebral atherosclerosis and insufficient perfusion are involved in the development of dementia including AD...
  10. doi request reprint The obesity related gene, FTO, interacts with APOE, and is associated with Alzheimer's disease risk: a prospective cohort study
    Lina Keller
    Aging Research Center, Department NVS, Karolinska Institutet and Stockholm University, Stockholm, Sweden
    J Alzheimers Dis 23:461-9. 2011
    ..Our results are in line with the recently reported association between FTO and reduced brain volume in cognitively healthy subjects...
  11. doi request reprint An active lifestyle postpones dementia onset by more than one year in very old adults
    Stephanie Paillard-Borg
    Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden
    J Alzheimers Dis 31:835-42. 2012
    ..These findings highlight the relevance of encouraging old adults to have active lifestyles, which could have a great impact on public health...
  12. pmc Early Cognitive Deficits in Type 2 Diabetes: A Population-Based Study
    Anna Marseglia
    Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden
    J Alzheimers Dis 53:1069-78. 2016
    ..Diabetes, especially uncontrolled diabetes, is associated with poorer performance in perceptual speed, category fluency, and attention/primary memory. VRFs, vascular disorders, and APOE status play a role in these associations. ..
  13. doi request reprint Influence of Incipient Dementia on Hospitalization for Primary Care Sensitive Conditions: A Population-Based Cohort Study
    Clément Pimouguet
    Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden
    J Alzheimers Dis 52:213-22. 2016
    ..Studies have reported that moderate/severe stages of dementia are linked to increased hospitalization rates, but little is known about the influence of incipient dementia on hospitalizations for primary care sensitive conditions (PCSCs)...
  14. doi request reprint Lifestyle change and the prevention of cognitive decline and dementia: what is the evidence?
    Martin Lövdén
    Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden
    Curr Opin Psychiatry 26:239-43. 2013
    ..Much recent research has, therefore, adopted an interventional focus. We review this work, highlight some methodological limitations, and provide recommendations for future research...
  15. doi request reprint Vascular and psychosocial factors in Alzheimer's disease: epidemiological evidence toward intervention
    Chengxuan Qiu
    Aging Research Center, Karolinska Institutet Stockholm University, Stockholm, Sweden
    J Alzheimers Dis 20:689-97. 2010
    ....
  16. doi request reprint Prudent diet may attenuate the adverse effects of Western diet on cognitive decline
    Behnaz Shakersain
    Aging Research Center, Center for Alzheimer Research, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden Electronic address
    Alzheimers Dement 12:100-9. 2016
    ..The influence of mixed dietary patterns on cognitive changes is unknown...
  17. pmc Prevalence, pharmacological treatment, and control of cardiometabolic risk factors among older people in central Stockholm: a population-based study
    Rui Wang
    Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet Stockholm University, Stockholm, Sweden
    PLoS ONE 10:e0119582. 2015
    ..Cardiometabolic risk factors and related cardiovascular diseases represent major threats to healthy aging...
  18. doi request reprint Leisure activities, cognition and dementia
    Hui Xin Wang
    Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Gavlegatan 16, 113 30 Stockholm, Sweden
    Biochim Biophys Acta 1822:482-91. 2012
    ..Further, well designed studies with long follow-up times are necessary. This article is part of a Special Issue entitled: Imaging Brain Aging and Neurodegenerative disease...
  19. ncbi request reprint Impact of tooth loss on walking speed decline over time in older adults: a population-based cohort study
    Anna Karin Welmer
    Department of Neurobiology, Care Sciences and Society, Aging Research Center, Karolinska Institutet and Stockholm University, Gavlegatan 16, 9tr, SE113 30, Stockholm, Sweden
    Aging Clin Exp Res . 2016
    ..Tooth loss has been linked to poor health such as chronic diseases and mobility limitations. Prospective evidence on the association between tooth loss and walking speed decline is however lacking...
  20. doi request reprint Impact of living alone on institutionalization and mortality: a population-based longitudinal study
    Clément Pimouguet
    1 Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden 2 INSERM, ISPED, Centre INSERM U897 Epidemiologie Biostatistique, Bordeaux, France 3 University of Bordeaux, Centre INSERM U897 Epidemiologie Biostatistique, Bordeaux, France
    Eur J Public Health 26:182-7. 2016
    ..We investigated that the impact of living alone on institutionalization and mortality in a population-based cohort of elderly people...
  21. doi request reprint Cognitive decline, dietary factors and gut-brain interactions
    Barbara Caracciolo
    Aging Research Center, Department of Neurobiology, Care Sciences and Society NVS, Karolinska Institutet and Stockholm University, Stockholm, Sweden Stress Research Institute, Stockholm University, Stockholm, Sweden Electronic address
    Mech Ageing Dev 136:59-69. 2014
    ..In addition to the traditional etiological pathways, new hypotheses, such as the role of the intestinal microbiome in cognitive function, have been suggested and warrant further investigation. ..
  22. doi request reprint Cognitive functioning among patients with diabetic foot
    Anna Marseglia
    Aging Research Center, Karolinska Institutet and Stockholm University, Stockholm, Sweden Institute of NeuroscienceAging section, Italian National Council Research CNR, Padua, Italy Electronic address
    J Diabetes Complications 28:863-8. 2014
    ..Using diabetic foot (DF) as an indicator of severe diabetes, we aimed to investigate the cognitive profile of DF patients and the relations between cognitive functioning and both diabetes complications and comorbidities...
  23. doi request reprint Tocopherols and tocotrienols plasma levels are associated with cognitive impairment
    Francesca Mangialasche
    Aging Research Center, Karolinska Institutet, Stockholm, Sweden
    Neurobiol Aging 33:2282-90. 2012
    ..Further, both disorders were associated with increased vitamin E damage. Low plasma tocopherols and tocotrienols levels are associated with increased odds of MCI and AD...