Affiliation: Karolinska Institutet
- Risk factors for early death in children with haemophagocytic lymphohistiocytosisHelena Trottestam
Childhood Cancer Research Unit, Department of Women s and Children s Health, Karolinska Institutet, Karolinska University Hospital Solna, Stockholm, Sweden
Acta Paediatr 101:313-8. 2012..A large proportion of deaths occur early into treatment. We investigated association with early death for laboratory and clinical parameters before the start of and 2 weeks into therapy...
- Treatment of the X-linked lymphoproliferative, Griscelli and Chédiak-Higashi syndromes by HLH directed therapyHelena Trottestam
Childhood Cancer Research Unit, Karolinska University Hospital, Department of Woman and Child Health, Karolinska Institutet, Stockholm, Sweden
Pediatr Blood Cancer 52:268-72. 2009..We wanted to investigate whether the treatment protocols for hemophagocytic lymphohistiocytosis (HLH) can also be used for these syndromes...
- Chemoimmunotherapy for hemophagocytic lymphohistiocytosis: long-term results of the HLH-94 treatment protocolHelena Trottestam
Department of Women s and Children s Health, Karolinska Institutet, Stockholm, Sweden
Blood 118:4577-84. 2011..001) or hepatomegaly (P = .007). To conclude, HLH-94 chemoimmunotherapy has considerably improved outcome in HLH. Collaborative efforts are needed to further reduce early mortality, HSCT-related mortality, and neurologic late effects...
- Frequency and spectrum of central nervous system involvement in 193 children with haemophagocytic lymphohistiocytosisAnnacarin Horne
Childhood Cancer Research Unit, Department of Woman and Child Health, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden
Br J Haematol 140:327-35. 2008..Prompt treatment of HLH at onset or relapse may reduce these complications...