Jingfeng Li

Summary

Affiliation: Karolinska Institutet
Country: Sweden

Publications

  1. ncbi request reprint Cloning of deleted sequences (CODE): A genomic subtraction method for enriching and cloning deleted sequences
    J Li
    Karolinska Institute, Stockholm, Sweden
    Biotechniques 31:788, 790, 792-3. 2001
  2. ncbi request reprint Inactivation of RASSF1C during in vivo tumor growth identifies it as a tumor suppressor gene
    Jingfeng Li
    Microbiology and Tumorbiology Center, Karolinska Institute, Stockholm 171 77, Sweden
    Oncogene 23:5941-9. 2004
  3. pmc High mutability of the tumor suppressor genes RASSF1 and RBSP3 (CTDSPL) in cancer
    Vladimir I Kashuba
    Department of Microbiology, Tumor and Cell Biology, Karolinska Institute, Stockholm, Sweden
    PLoS ONE 4:e5231. 2009
  4. ncbi request reprint Functional characterization of the candidate tumor suppressor gene NPRL2/G21 located in 3p21.3C
    Jingfeng Li
    Microbiology and Tumor Biology Center, Center for Genomics and Bioinformatics, Karolinska Institute, Stockholm, Sweden
    Cancer Res 64:6438-43. 2004
  5. pmc HYAL1 and HYAL2 inhibit tumour growth in vivo but not in vitro
    Fuli Wang
    Microbiology and Tumour Biology Center, Karolinska Institute, Stockholm, Sweden
    PLoS ONE 3:e3031. 2008
  6. pmc RBSP3 (HYA22) is a tumor suppressor gene implicated in major epithelial malignancies
    Vladimir I Kashuba
    Microbiology and Tumor Biology Center and Center for Genomics and Bioinformatics, Karolinska Institute, 17177 Stockholm, Sweden
    Proc Natl Acad Sci U S A 101:4906-11. 2004
  7. ncbi request reprint Consistent downregulation of human lactoferrin gene, in the common eliminated region 1 on 3p21.3, following tumor growth in severe combined immunodeficient (SCID) mice
    Ying Yang
    Microbiology and Tumor Biology Center, Karolinska Institute, Nobelsvägen 16, 171 77 Stockholm, Sweden
    Cancer Lett 191:155-64. 2003
  8. pmc NotI subtraction and NotI-specific microarrays to detect copy number and methylation changes in whole genomes
    Jingfeng Li
    Microbiology and Tumor Biology Center, Karolinska Institute, 171 77 Stockholm, Sweden
    Proc Natl Acad Sci U S A 99:10724-9. 2002

Detail Information

Publications8

  1. ncbi request reprint Cloning of deleted sequences (CODE): A genomic subtraction method for enriching and cloning deleted sequences
    J Li
    Karolinska Institute, Stockholm, Sweden
    Biotechniques 31:788, 790, 792-3. 2001
    ..This procedure resulted in the rapid isolation and efficient cloning of genomic sequences homozygously deleted from the driver DNA sample, but present in the tester DNA fraction...
  2. ncbi request reprint Inactivation of RASSF1C during in vivo tumor growth identifies it as a tumor suppressor gene
    Jingfeng Li
    Microbiology and Tumorbiology Center, Karolinska Institute, Stockholm 171 77, Sweden
    Oncogene 23:5941-9. 2004
    ..In addition, RASSF1C was shown to induce cell cycle arrest in KRC/Y cells. These results strongly imply that like RASSF1A the RASSF1C gene could serve a tumor suppressor function...
  3. pmc High mutability of the tumor suppressor genes RASSF1 and RBSP3 (CTDSPL) in cancer
    Vladimir I Kashuba
    Department of Microbiology, Tumor and Cell Biology, Karolinska Institute, Stockholm, Sweden
    PLoS ONE 4:e5231. 2009
    ..Somatic hypermutation is a powerful mechanism for generation of different mutations. It was shown previously that somatic hypermutability of proto-oncogenes can induce development of lymphomas...
  4. ncbi request reprint Functional characterization of the candidate tumor suppressor gene NPRL2/G21 located in 3p21.3C
    Jingfeng Li
    Microbiology and Tumor Biology Center, Center for Genomics and Bioinformatics, Karolinska Institute, Stockholm, Sweden
    Cancer Res 64:6438-43. 2004
    ..This study, together with previously obtained results, indicates that NPRL2 is a multiple tumor suppressor gene...
  5. pmc HYAL1 and HYAL2 inhibit tumour growth in vivo but not in vitro
    Fuli Wang
    Microbiology and Tumour Biology Center, Karolinska Institute, Stockholm, Sweden
    PLoS ONE 3:e3031. 2008
    ..Until now TSGs which were isolated from AP20 and LUCA regions (e.g.G21/NPRL2, RASSF1A, RASSF1C, SEMA3B, SEMA3F, RBSP3) were shown to inhibit tumour cell growth both in vitro and in vivo...
  6. pmc RBSP3 (HYA22) is a tumor suppressor gene implicated in major epithelial malignancies
    Vladimir I Kashuba
    Microbiology and Tumor Biology Center and Center for Genomics and Bioinformatics, Karolinska Institute, 17177 Stockholm, Sweden
    Proc Natl Acad Sci U S A 101:4906-11. 2004
    ....
  7. ncbi request reprint Consistent downregulation of human lactoferrin gene, in the common eliminated region 1 on 3p21.3, following tumor growth in severe combined immunodeficient (SCID) mice
    Ying Yang
    Microbiology and Tumor Biology Center, Karolinska Institute, Nobelsvägen 16, 171 77 Stockholm, Sweden
    Cancer Lett 191:155-64. 2003
    ..Promoter methylation and/or rearrangement of the insertion site may be responsible for human LF downregulation in mouse fibrosarcoma derived tumors...
  8. pmc NotI subtraction and NotI-specific microarrays to detect copy number and methylation changes in whole genomes
    Jingfeng Li
    Microbiology and Tumor Biology Center, Karolinska Institute, 171 77 Stockholm, Sweden
    Proc Natl Acad Sci U S A 99:10724-9. 2002
    ..These microarrays, when probed with NRs, can simultaneously detect copy number changes and methylation. NotI microarrays offer a powerful tool with which to study carcinogenesis...