Affiliation: Karolinska University Hospital
- Bronchoalveolar lavage in COPD: fluid recovery correlates with the degree of emphysemaJ M Löfdahl
Dept of Medicine, Division of Respiratory Medicine, Karolinska University Hospital, Solna, Stockholm, Sweden
Eur Respir J 25:275-81. 2005..The present study underlines the importance of careful phenotyping of chronic obstructive pulmonary disease patients...
- Different inflammatory cell pattern and macrophage phenotype in chronic obstructive pulmonary disease patients, smokers and non-smokersJ M Löfdahl
Department of Medicine, Division of Respiratory Medicine, Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden
Clin Exp Immunol 145:428-37. 2006..Some alterations were found in smokers compared to non-smokers, thus indicating that changes in AM phenotype may be associated with smoking per se. The functional relevance of our findings remains to be elucidated...
- Increased intraepithelial T-cells in stable COPDMagnus J Löfdahl
Department of Medicine, Division of Respiratory Medicine, Karolinska Institutet, Solna, Stockholm, Sweden
Respir Med 102:1812-8. 2008..We hypothesised that intraepithelial T-cells play a role in the response to lung irritants and that the T-cell populations would be altered and associated with signs of inflammation in COPD...
- Tenascin-C and alpha-smooth muscle actin positive cells are increased in the large airways in patients with COPDMagnus Löfdahl
Dept of Medicine, Karolinska Institutet, Karolinska University Hospital Solna, Stockholm Sweden
Respir Res 12:48. 2011..Our aim was to elucidate whether this expression correlated with smoking or with disease development...
- Detection of Chlamydia pneumoniae on cytospin preparations from bronchoalveolar lavage in COPD patients and in lung tissue from advanced emphysemaEva Brandén
Department of Medicine, Division of Respiratory Medicine, Karolinska Institutet, Stockholm, Sweden
Int J Chron Obstruct Pulmon Dis 2:643-50. 2007..In conclusion, the assays used for detection of C. pneumoniae in lung tissue are feasible, and could be adapted in adequately powered studies to further confirm an association between C. pneumoniae infection and COPD...
- Reduced intracellular oxygen radical production in whole blood leukocytes from COPD patients and asymptomatic smokersLena Wehlin
Division of Clinical Immunology and Allergy, Department of Medicine, Karolinska Institutet, Karolinska University Hospital, L2 04, S 171 76 Stockholm, Sweden
Chest 128:2051-8. 2005..In the present study, we sought to investigate its impact on different peripheral leukocyte subpopulations that are recognized as important effector cells in the lung tissue...