Henrik Larsson

Summary

Affiliation: Karolinska Institutet
Country: Sweden

Publications

  1. pmc Risk of bipolar disorder and schizophrenia in relatives of people with attention-deficit hyperactivity disorder
    Henrik Larsson
    Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden
    Br J Psychiatry 203:103-6. 2013
  2. doi request reprint Genetic and environmental influences on adult attention deficit hyperactivity disorder symptoms: a large Swedish population-based study of twins
    H Larsson
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    Psychol Med 43:197-207. 2013
  3. doi request reprint Childhood attention-deficit hyperactivity disorder as an extreme of a continuous trait: a quantitative genetic study of 8,500 twin pairs
    Henrik Larsson
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    J Child Psychol Psychiatry 53:73-80. 2012
  4. ncbi request reprint Relationships between parental negativity and childhood antisocial behavior over time: a bidirectional effects model in a longitudinal genetically informative design
    Henrik Larsson
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, P O Box 281, 171 77, Stockholm, Sweden
    J Abnorm Child Psychol 36:633-45. 2008
  5. doi request reprint Developmental trajectories of DSM-IV symptoms of attention-deficit/hyperactivity disorder: genetic effects, family risk and associated psychopathology
    Henrik Larsson
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    J Child Psychol Psychiatry 52:954-63. 2011
  6. pmc Serious transport accidents in adults with attention-deficit/hyperactivity disorder and the effect of medication: a population-based study
    Zheng Chang
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    JAMA Psychiatry 71:319-25. 2014
  7. doi request reprint Developmental twin study of attention problems: high heritabilities throughout development
    Zheng Chang
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    JAMA Psychiatry 70:311-8. 2013
  8. ncbi request reprint The Risk of Treatment-Emergent Mania With Methylphenidate in Bipolar Disorder
    Alexander Viktorin
    From the Department of Medical Epidemiology and Biostatistics and the Department of Clinical Neuroscience, Karolinska Institutet, Stockholm the Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York the Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia the Department of Psychological and Brain Sciences, Indiana University, Bloomington Astrid Lindgren Children s Hospital, Karolinska University Hospital, Stockholm the Department of Medical Sciences, Orebro University, Orebro, Sweden and the Institute of Neuroscience and Physiology, University of Gothenburg, Gothenburg, Sweden
    Am J Psychiatry . 2016
  9. doi request reprint Coexisting psychiatric problems and stressful life events in adults with symptoms of ADHD--a large Swedish population-based study of twins
    Bettina Friedrichs
    Karolinska Institutet, Stockholm, Sweden
    J Atten Disord 16:13-22. 2012
  10. doi request reprint Selective serotonin re-uptake inhibitor use during pregnancy: association with offspring birth size and gestational age
    Alexander Viktorin
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    Int J Epidemiol 45:170-7. 2016

Detail Information

Publications71

  1. pmc Risk of bipolar disorder and schizophrenia in relatives of people with attention-deficit hyperactivity disorder
    Henrik Larsson
    Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden
    Br J Psychiatry 203:103-6. 2013
    ..Attention-deficit hyperactivity disorder (ADHD) is associated with bipolar disorder and schizophrenia, and it has been suggested that combined bipolar disorder and ADHD is aetiologically distinct from the pure disorders...
  2. doi request reprint Genetic and environmental influences on adult attention deficit hyperactivity disorder symptoms: a large Swedish population-based study of twins
    H Larsson
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    Psychol Med 43:197-207. 2013
    ..We therefore aimed to investigate the impact of genetic and environmental influences on the inattentive and hyperactive-impulsive symptoms of ADHD in adults...
  3. doi request reprint Childhood attention-deficit hyperactivity disorder as an extreme of a continuous trait: a quantitative genetic study of 8,500 twin pairs
    Henrik Larsson
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    J Child Psychol Psychiatry 53:73-80. 2012
    ..The aim of this study was to assess genetic links between the extreme and the subthreshold range of ADHD symptoms...
  4. ncbi request reprint Relationships between parental negativity and childhood antisocial behavior over time: a bidirectional effects model in a longitudinal genetically informative design
    Henrik Larsson
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, P O Box 281, 171 77, Stockholm, Sweden
    J Abnorm Child Psychol 36:633-45. 2008
    ..We also found evidence of genetically mediated child effects; in which genetically influenced antisocial behavior evoke parental negativity towards the child...
  5. doi request reprint Developmental trajectories of DSM-IV symptoms of attention-deficit/hyperactivity disorder: genetic effects, family risk and associated psychopathology
    Henrik Larsson
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    J Child Psychol Psychiatry 52:954-63. 2011
    ....
  6. pmc Serious transport accidents in adults with attention-deficit/hyperactivity disorder and the effect of medication: a population-based study
    Zheng Chang
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    JAMA Psychiatry 71:319-25. 2014
    ..Most important, it is also unclear whether ADHD medication reduces this risk...
  7. doi request reprint Developmental twin study of attention problems: high heritabilities throughout development
    Zheng Chang
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    JAMA Psychiatry 70:311-8. 2013
    ..The genetic and environmental link between attention-deficit/hyperactivity disorder in childhood and the adult manifestation of the disorder is poorly understood because of a lack of longitudinal studies with cross-informant data...
  8. ncbi request reprint The Risk of Treatment-Emergent Mania With Methylphenidate in Bipolar Disorder
    Alexander Viktorin
    From the Department of Medical Epidemiology and Biostatistics and the Department of Clinical Neuroscience, Karolinska Institutet, Stockholm the Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York the Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia the Department of Psychological and Brain Sciences, Indiana University, Bloomington Astrid Lindgren Children s Hospital, Karolinska University Hospital, Stockholm the Department of Medical Sciences, Orebro University, Orebro, Sweden and the Institute of Neuroscience and Physiology, University of Gothenburg, Gothenburg, Sweden
    Am J Psychiatry . 2016
    ..The authors sought to determine the risk of treatment-emergent mania associated with methylphenidate, used in monotherapy or with a concomitant mood-stabilizing medication, in patients with bipolar disorder...
  9. doi request reprint Coexisting psychiatric problems and stressful life events in adults with symptoms of ADHD--a large Swedish population-based study of twins
    Bettina Friedrichs
    Karolinska Institutet, Stockholm, Sweden
    J Atten Disord 16:13-22. 2012
    ..To explore the associations of subtypes of adult ADHD with other psychiatric problems, stressful life events, and sex differences...
  10. doi request reprint Selective serotonin re-uptake inhibitor use during pregnancy: association with offspring birth size and gestational age
    Alexander Viktorin
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    Int J Epidemiol 45:170-7. 2016
    ..We aimed to examine the effects of prenatal SSRI exposure on offspring size outcomes and gestational age, and disentangle whether associations observed were due to the medication or other factors...
  11. doi request reprint A longitudinal study of adolescent psychotic experiences and later development of substance use disorder and suicidal behavior
    Martin Cederlöf
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Sweden Electronic address
    Schizophr Res . 2016
    ..Also, the potential dose-response relationship between these phenomena remains unknown...
  12. doi request reprint Association of Resting Heart Rate and Blood Pressure in Late Adolescence With Subsequent Mental Disorders: A Longitudinal Population Study of More Than 1 Million Men in Sweden
    Antti Latvala
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden2Department of Public Health, University of Helsinki, Helsinki, Finland
    JAMA Psychiatry 73:1268-1275. 2016
    ....
  13. doi request reprint The association between childhood autistic traits and adolescent psychotic experiences is explained by general neuropsychiatric problems
    Martin Cederlöf
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    Am J Med Genet B Neuropsychiatr Genet 171:153-9. 2016
    ..Twin analyses revealed that the association between the general neuropsychiatric problems factor and auditory hallucinations was driven by shared genetic influences. © 2015 Wiley Periodicals, Inc. ..
  14. pmc Stimulant ADHD medication and risk for substance abuse
    Zheng Chang
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    J Child Psychol Psychiatry 55:878-85. 2014
    ..There are persistent concerns of long-term effects of stimulant ADHD medication on the development of substance abuse...
  15. doi request reprint Association between ASMT and autistic-like traits in children from a Swedish nationwide cohort
    Lina Jonsson
    Departments of aPharmacology bForensic Psychiatry, Institute of Neuroscience and Physiology at the Sahlgrenska Academy cGillberg Neuropsychiatry Centre, Institute of Neuroscience and Physiology, University of Gothenburg dR and D Unit, Swedish Prison and Probation Service, Gothenburg eDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    Psychiatr Genet 24:21-7. 2014
    ....
  16. doi request reprint A longitudinal twin study of the direction of effects between psychopathic personality and antisocial behaviour
    Mats Forsman
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    J Child Psychol Psychiatry 51:39-47. 2010
    ..The aim in this study was to investigate the direction of effects between psychopathic personality and antisocial behaviour, and to investigate the genetic and environmental contribution to this association...
  17. doi request reprint Association of Perinatal Risk Factors With Obsessive-Compulsive Disorder: A Population-Based Birth Cohort, Sibling Control Study
    Gustaf Brander
    Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
    JAMA Psychiatry 73:1135-1144. 2016
    ..Previous reports were based on small, retrospective, specialist clinic-based studies that were unable to rigorously control for unmeasured environmental and genetic confounding...
  18. pmc Obsessive-Compulsive Disorder, Psychosis, and Bipolarity: A Longitudinal Cohort and Multigenerational Family Study
    Martin Cederlöf
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    Schizophr Bull 41:1076-83. 2015
    ..We conclude that OCD is etiologically related to both schizophrenia spectrum and bipolar disorders. The results have implications for current gene-searching efforts and for clinical practice...
  19. doi request reprint Childhood neurodevelopmental problems and adolescent bully victimization: population-based, prospective twin study in Sweden
    Peggy Törn
    Department of Medical Epidemiology and Biostatistics MEB, Karolinska Institutet, Stockholm, Sweden
    Eur Child Adolesc Psychiatry 24:1049-59. 2015
    ..The longitudinal design and twin analyses indicated that these associations might be causal. Knowledge of these vulnerabilities may be important when designing risk assessment and prevention strategies. ..
  20. doi request reprint The association between Darier disease, bipolar disorder, and schizophrenia revisited: a population-based family study
    Martin Cederlöf
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    Bipolar Disord 17:340-4. 2015
    ..It is, however, unknown whether these associations exist also in the general population, and the objective of this study was to examine this question...
  21. pmc Maternal age at childbirth and risk for ADHD in offspring: a population-based cohort study
    Zheng Chang
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden, Department of Psychiatry, University of Oxford, Oxford, UK, Department of Psychological and Brain Sciences, Indiana University, Bloomington, IN, USA and Astrid Lindgren Children s Hospital, Karolinska University Hospital, Stockholm, Sweden Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden, Department of Psychiatry, University of Oxford, Oxford, UK, Department of Psychological and Brain Sciences, Indiana University, Bloomington, IN, USA and Astrid Lindgren Children s Hospital, Karolinska University Hospital, Stockholm, Sweden
    Int J Epidemiol 43:1815-24. 2014
    ..However, it is not clear whether young maternal age is causally associated with poor offspring outcomes or confounded by familial factors...
  22. pmc The familial risk of autism
    Sven Sandin
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Sweden2Department of Psychosis Studies, Institute of Psychiatry, King s College London, United Kingdom
    JAMA 311:1770-7. 2014
    ..Autism spectrum disorder (ASD) aggregates in families, but the individual risk and to what extent this is caused by genetic factors or shared or nonshared environmental factors remains unresolved...
  23. doi request reprint Klinefelter syndrome and risk of psychosis, autism and ADHD
    Martin Cederlöf
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Box 281, SE 171 77 Stockholm, Sweden Electronic address
    J Psychiatr Res 48:128-30. 2014
    ..Schizophrenia, bipolar disorder, autism spectrum disorders and ADHD might be overrepresented in Klinefelter syndrome, but previous investigations have yielded inconclusive results...
  24. doi request reprint The effects of childhood ADHD symptoms on early-onset substance use: a Swedish twin study
    Zheng Chang
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, P O Box 281, 171 77 Stockholm, Sweden
    J Abnorm Child Psychol 40:425-35. 2012
    ..Our results indicated that hyperactivity/impulsivity, but not inattention, is an important early predictor for early-onset substance use, and a shared genetic susceptibility is suggested to explain this association...
  25. doi request reprint The Swedish Twin Registry: establishment of a biobank and other recent developments
    Patrik K E Magnusson
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    Twin Res Hum Genet 16:317-29. 2013
    ..Coverage by year of birth, zygosity determination, ethnic heterogeneity, and influences of in vitro fertilization are also described...
  26. ncbi request reprint Genetic and environmental contributions to stability and change of ADHD symptoms between 8 and 13 years of age: a longitudinal twin study
    Jan Olov Larsson
    Department of Child and Adolescent Psychiatry, The Karolinska Hospital, Stockholm, Sweden
    J Am Acad Child Adolesc Psychiatry 43:1267-75. 2004
    ..To study the genetic and environmental contributions to stability and change of attention-deficit/hyperactivity disorder (ADHD) symptoms between 8 and 9 and 13 and 14 years of age...
  27. doi request reprint Genetic effects explain the stability of psychopathic personality from mid- to late adolescence
    Mats Forsman
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    J Abnorm Psychol 117:606-17. 2008
    ..Thus, the model provides evidence for etiologic generality and etiologic specificity for the stability of psychopathic personality between mid- and late adolescence...
  28. doi request reprint Internalizing behavior in adolescent girls affects parental emotional overinvolvement: a cross-lagged twin study
    Therese Moberg
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    Behav Genet 41:223-33. 2011
    ....
  29. doi request reprint Familial aggregation of attention-deficit/hyperactivity disorder
    Qi Chen
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    J Child Psychol Psychiatry . 2016
    ..Attention-deficit/hyperactivity disorder (ADHD) aggregates in families. To date, the strength, pattern, and characteristics of the familial aggregation have not been thoroughly assessed in a population-based family sample...
  30. pmc Increased Risk for Substance Use-Related Problems in Autism Spectrum Disorders: A Population-Based Cohort Study
    Agnieszka Butwicka
    Department of Medical Epidemiology and Biostatistics, MEB, Karolinska Institutet, Box 281, 171 77, Stockholm, Sweden
    J Autism Dev Disord . 2016
    ..We conclude that ASD is a risk factor for substance use-related problems. The elevated risks among relatives of probands with ASD suggest shared familial (genetic and/or shared environmental) liability...
  31. doi request reprint Shared familial risk factors between attention-deficit/hyperactivity disorder and overweight/obesity - a population-based familial coaggregation study in Sweden
    Qi Chen
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    J Child Psychol Psychiatry . 2017
    ..Despite meta-analytic evidence for the association between attention-deficit/hyperactivity disorder (ADHD) and overweight/obesity, the mechanisms underlying the association are yet to be fully understood...
  32. doi request reprint Familial Liability for Eating Disorders and Suicide Attempts: Evidence From a Population Registry in Sweden
    Shuyang Yao
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    JAMA Psychiatry 73:284-91. 2016
    ..Suicide attempts are common in individuals with eating disorders. More precise understanding of the mechanisms underlying their concomitant occurrence is needed...
  33. pmc Birth weight as an independent predictor of ADHD symptoms: a within-twin pair analysis
    Erik Pettersson
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    J Child Psychol Psychiatry 56:453-9. 2015
    ..Second, it remains uncertain whether the association between birth weight and ADHD symptom severity is confounded by familial factors...
  34. pmc Does population density and neighborhood deprivation predict schizophrenia? A nationwide Swedish family-based study of 2.4 million individuals
    Amir Sariaslan
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    Schizophr Bull 41:494-502. 2015
    ..Previous studies may have overemphasized the etiological importance of these environmental factors. ..
  35. pmc Association Between Prescription of Major Psychotropic Medications and Violent Reoffending After Prison Release
    Zheng Chang
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden2Department of Psychiatry, Warneford Hospital, University of Oxford, Oxford, England
    JAMA 316:1798-1807. 2016
    ..Individuals released from prison have high rates of violent reoffending, and there is uncertainty about whether pharmacological treatments reduce reoffending risk...
  36. pmc Nationwide population-based cohort study of psychiatric disorders in individuals with Ehlers-Danlos syndrome or hypermobility syndrome and their siblings
    Martin Cederlöf
    Department Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, 17177, Sweden
    BMC Psychiatry 16:207. 2016
    ..To assess the risk of psychiatric disorders in Ehlers-Danlos syndrome (EDS) and hypermobility syndrome...
  37. pmc Patterns of Nonrandom Mating Within and Across 11 Major Psychiatric Disorders
    Ashley E Nordsletten
    Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
    JAMA Psychiatry 73:354-61. 2016
    ..However, despite the potential etiological implications, the scale of nonrandom mating within and across major psychiatric conditions remains unclear...
  38. pmc Association of Labor Induction With Offspring Risk of Autism Spectrum Disorders
    Anna Sara Oberg
    Department of Epidemiology, Harvard T H Chan School of Public Health, Boston, Massachusetts2Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    JAMA Pediatr 170:e160965. 2016
    ..Induction of labor is a frequently performed obstetrical intervention. It would thus be of great concern if reported associations between labor induction and offspring risk of autism spectrum disorders (ASD) reflected causal influence...
  39. doi request reprint Acute intermittent porphyria: comorbidity and shared familial risks with schizophrenia and bipolar disorder in Sweden
    Martin Cederlöf
    Martin Cederlöf, MSc, Sarah E Bergen, PhD, Henrik Larsson, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm Mikael Landén, MD, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm and Institute of Neuroscience and Physiology, University of Gothenburg, Gothenburg, Sweden Paul Lichtenstein, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    Br J Psychiatry 207:556-7. 2015
    ..Similarly, relatives of individuals with AIP had double the risk of schizophrenia or bipolar disorder, suggesting that these associations may be as a result of common genetic influences. ..
  40. pmc Childhood family income, adolescent violent criminality and substance misuse: quasi-experimental total population study
    Amir Sariaslan
    Amir Sariaslan, MSc, Henrik Larsson, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden Brian D Onofrio, PhD, Department of Psychological and Brain Sciences, Indiana University, Bloomington, Indiana, USA Niklas Långström, MD, PhD, Paul Lichtenstein, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    Br J Psychiatry 205:286-90. 2014
    ..Aims To investigate whether childhood family income predicts subsequent violent criminality and substance misuse and whether the associations are in turn explained by unobserved familial risk factors...
  41. doi request reprint Relative immaturity and ADHD: findings from nationwide registers, parent- and self-reports
    Linda Halldner
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden Karolinska Institutet Center of Neurodevelopmental Disorders KIND, Karolinska Institutet, Stockholm, Sweden
    J Child Psychol Psychiatry 55:897-904. 2014
    ..We addressed if immaturity relative to peers reflected in birth month increases the likelihood of ADHD diagnosis and treatment...
  42. pmc Maternal pre-pregnancy body mass index and offspring attention deficit hyperactivity disorder: a population-based cohort study using a sibling-comparison design
    Qi Chen
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden, Department of Social Sciences Psychology, Mid Sweden University, Ostersund, Sweden, Department of Epidemiology and Biostatistics, Imperial College London, London, UK, Medical Research Council Social Genetic Developmental Psychiatry Centre, King s College London, London, UK, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden and Department of Psychological and Brain Sciences, Indiana University, Bloomington, IN, USA
    Int J Epidemiol 43:83-90. 2014
    ..High maternal pre-pregnancy body mass index (BMI) is associated with increased risk of offspring attention deficit hyperactivity disorder (ADHD). However, the role of unmeasured familial confounding for this association remains unclear...
  43. pmc Drug treatment for attention-deficit/hyperactivity disorder and suicidal behaviour: register based study
    Qi Chen
    Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Box 281, 17177 Stockholm, Sweden
    BMJ 348:g3769. 2014
    ..To investigate the association between drug treatment for attention-deficit/hyperactivity disorder (ADHD) and risk of concomitant suicidal behaviour among patients with ADHD...
  44. doi request reprint Sex differences in jealousy: a population-based twin study in Sweden
    Hasse Walum
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    Twin Res Hum Genet 16:941-7. 2013
    ..Even though our results from the mean value analyses are in line with the theory of evolved sex differences in jealousy, we could not identify any sex differences on a genetic level. ..
  45. pmc Medication for attention deficit-hyperactivity disorder and criminality
    Paul Lichtenstein
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    N Engl J Med 367:2006-14. 2012
    ..Attention deficit-hyperactivity disorder (ADHD) is a common disorder that has been associated with criminal behavior in some studies. Pharmacologic treatment is available for ADHD and may reduce the risk of criminality...
  46. ncbi request reprint A genetic factor explains most of the variation in the psychopathic personality
    Henrik Larsson
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    J Abnorm Psychol 115:221-30. 2006
    ..The authors propose that this latent psychopathic personality factor is a meaningful target for future etiological research...
  47. ncbi request reprint Genetic contributions to the development of ADHD subtypes from childhood to adolescence
    Henrik Larsson
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm
    J Am Acad Child Adolesc Psychiatry 45:973-81. 2006
    ..The aim of this study was to examine genetic influences contributing to the development of hyperactive-impulsive symptoms and inattentive symptoms of ADHD from childhood to adolescence...
  48. pmc Medication for Attention-Deficit/Hyperactivity Disorder and Risk for Depression: A Nationwide Longitudinal Cohort Study
    Zheng Chang
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden Electronic address
    Biol Psychiatry 80:916-922. 2016
    ..Attention-deficit/hyperactivity disorder (ADHD) is associated with high rates of psychiatric comorbidity, including depression. However, it is unclear whether ADHD medication increases or decreases the risk for depression...
  49. doi request reprint Systematic review of environmental risk factors for Obsessive-Compulsive Disorder: A proposed roadmap from association to causation
    Gustaf Brander
    Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden Electronic address
    Neurosci Biobehav Rev 65:36-62. 2016
    ..To synthesize the current knowledge on possible environmental risk factors for Obsessive-Compulsive Disorder (OCD)...
  50. pmc Factors Associated With Adherence to Methylphenidate Treatment in Adult Patients With Attention-Deficit/Hyperactivity Disorder and Substance Use Disorders
    Charlotte Skoglund
    From the Division of Psychiatry, Department of Clinical Neuroscience, Department of Medicine Solna, Center for Pharmacoepidemiology, Department of Medical Epidemiology and Biostatistics, Lung and Allergy Unit, Astrid Lindgren Children s Hospital, Karolinska University Hospital, Stockholm, Sweden and Department of Psychological and Brain Sciences Indiana University, Bloomington, IN
    J Clin Psychopharmacol 36:222-8. 2016
    ..In conclusion, this study shows that higher MPH doses were associated with long-term treatment adherence in individuals with attention-deficit/hyperactivity disorder and SUD...
  51. doi request reprint Pharmacoepidemiology of obsessive-compulsive disorder: A Swedish nationwide cohort study
    Kayoko Isomura
    Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden Electronic address
    Eur Neuropsychopharmacol 26:693-704. 2016
    ..Dissemination of best-practice prescription guidelines for OCD is a major educational goal for the future. Monitoring of these prescription patterns over time is warranted. ..
  52. pmc Substance use disorders, psychiatric disorders, and mortality after release from prison: a nationwide longitudinal cohort study
    Zheng Chang
    Department of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    Lancet Psychiatry 2:422-30. 2015
    ..We aimed to investigate the association between psychiatric disorders and mortality in people released from prison in Sweden...
  53. pmc Codevelopment of ADHD and externalizing behavior from childhood to adulthood
    Ralf Kuja-Halkola
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    J Child Psychol Psychiatry 56:640-7. 2015
    ....
  54. doi request reprint A Longitudinal Study of Resting Heart Rate and Violent Criminality in More Than 700 000 Men
    Antti Latvala
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden2Department of Public Health, University of Helsinki, Helsinki, Finland
    JAMA Psychiatry 72:971-8. 2015
    ....
  55. pmc Psychiatric disorders and violent reoffending: a national cohort study of convicted prisoners in Sweden
    Zheng Chang
    Department of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    Lancet Psychiatry 2:891-900. 2015
    ..However, whether psychiatric disorders are risk factors for reoffending is still unknown. We aimed to examine the association between psychiatric disorders, including substance use disorder, and violent reoffending...
  56. pmc Familial confounding of the association between maternal smoking during pregnancy and ADHD in offspring
    Charlotte Skoglund
    Department of Clinical Neuroscience, Karolinska Institute, Stockholm, Sweden
    J Child Psychol Psychiatry 55:61-8. 2014
    ....
  57. doi request reprint Familial Risks of Tourette Syndrome and Chronic Tic Disorders. A Population-Based Cohort Study
    David Mataix-Cols
    Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
    JAMA Psychiatry 72:787-93. 2015
    ..Twin studies have been either very small or based on parent-reported tics in population-based (nonclinical) twin samples...
  58. doi request reprint Bipolar disorder and its relation to major psychiatric disorders: a family-based study in the Swedish population
    Jie Song
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm
    Bipolar Disord 17:184-93. 2015
    ....
  59. doi request reprint Attention-deficit/hyperactivity disorder and risk for substance use disorders in relatives
    Charlotte Skoglund
    Departments of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden Electronic address
    Biol Psychiatry 77:880-6. 2015
    ..The main aim of this study was to explore whether the overlap between ADHD and SUD could be explained by shared genetic and environmental factors or by harmful effects of ADHD medication...
  60. pmc Maternal smoking during pregnancy and adverse outcomes in offspring: genetic and environmental sources of covariance
    Ralf Kuja-Halkola
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, P O Box 281, 171 77, Stockholm, Sweden
    Behav Genet 44:456-67. 2014
    ..The results suggest that the associations between SDP in mothers and cognition and externalizing behaviors in their offspring is primarily due to genetic effects that influence the behaviors in both generations. ..
  61. doi request reprint Between-within models for survival analysis
    Arvid Sjölander
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm
    Stat Med 32:3067-76. 2013
    ....
  62. pmc Variation in the oxytocin receptor gene is associated with pair-bonding and social behavior
    Hasse Walum
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    Biol Psychiatry 71:419-26. 2012
    ..Here we investigate the extent to which genetic variants in the oxytocin receptor gene (OXTR) are associated with pair-bonding and related social behaviors in humans...
  63. ncbi request reprint The Swedish Twin study of CHild and Adolescent Development: the TCHAD-study
    Paul Lichtenstein
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Sweden
    Twin Res Hum Genet 10:67-73. 2007
    ..In this article we describe the sample, data collections, and measures used. In addition, we provide some key findings from the study, focusing on antisocial behavior, criminality, and psychopathic personality...
  64. doi request reprint Premature mortality in autism spectrum disorder
    Tatja Hirvikoski
    Tatja Hirvikoski, PhD, Department of Women s and Children s Health, Pediatric Neuropsychiatry Unit, Center for Neurodevelopmental Disorders at Karolinska Institutet KIND, Karolinska Institutet, Stockholm, Sweden and Habilitation and Health, Stockholm County Council, Sweden Ellenor Mittendorfer Rutz, PhD, Department of Clinical Neuroscience, Division of Insurance Medicine, Karolinska Institutet, Stockholm, Sweden Marcus Boman, Bsc, Henrik Larsson, PhD, Paul Lichtenstein, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden Sven Bölte, PhD, Department of Women s and Children s Health, Pediatric Neuropsychiatry Unit, Center for Neurodevelopmental Disorders at Karolinska Institutet KIND, Karolinska Institutet, Stockholm and Division of Child and Adolescent Psychiatry, Stockholm County Council, Sweden
    Br J Psychiatry 208:232-8. 2016
    ..Mortality has been suggested to be increased in autism spectrum disorder (ASD)...
  65. pmc Fetal growth and psychiatric and socioeconomic problems: population-based sibling comparison
    Quetzal A Class
    Quetzal A Class, BS, Martin E Rickert, PhD, Department of Psychological and Brain Sciences, Indiana University, Bloomington, Indiana Henrik Larsson, PhD, Paul Lichtenstein, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden Brian M D Onofrio, PhD, Department of Psychological and Brain Sciences, Indiana University, Bloomington, Indiana
    Br J Psychiatry 205:355-61. 2014
    ..It is unclear whether associations between fetal growth and psychiatric and socioeconomic problems are consistent with causal mechanisms...
  66. doi request reprint Common etiological factors of attention-deficit/hyperactivity disorder and suicidal behavior: a population-based study in Sweden
    Therese Ljung
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    JAMA Psychiatry 71:958-64. 2014
    ....
  67. pmc Family income in early childhood and subsequent attention deficit/hyperactivity disorder: a quasi-experimental study
    Henrik Larsson
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    J Child Psychol Psychiatry 55:428-35. 2014
    ..The aim of this study was to determine the extent to which the association between family income in early childhood and subsequent ADHD depends on measured and unmeasured selection factors...
  68. doi request reprint Long-Term Treatment Outcome in Adult Male Prisoners With Attention-Deficit/Hyperactivity Disorder: Three-Year Naturalistic Follow-Up of a 52-Week Methylphenidate Trial
    Ylva Ginsberg
    From the Division of Psychiatry, Department of Clinical Neuroscience, and Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    J Clin Psychopharmacol 35:535-43. 2015
    ..Most study completers were employed and had no relapse in substance misuse or criminality. These results suggest that motivational support and continued medication are important for improved outcome in adult criminal offenders with ADHD...
  69. doi request reprint Longitudinal Stability of Genetic and Environmental Influences on Irritability: From Childhood to Young Adulthood
    Roxann Roberson-Nay
    From the Department of Psychiatry and the Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond the Section on Bipolar Spectrum Disorders, Division of Intramural Research Programs, NIMH, Bethesda, Md and the Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm
    Am J Psychiatry 172:657-64. 2015
    ..This study examined the temporal pattern of genetic and environmental effects on irritability using data from a prospective, four-wave longitudinal twin study...
  70. pmc Quantitative genetic studies of antisocial behaviour
    Essi Viding
    Department of Psychology, University College London, Gower Street, London WC1E 6BT, UK
    Philos Trans R Soc Lond B Biol Sci 363:2519-27. 2008
    ..Quantitative genetic research is also important in advancing the understanding of the mechanisms by which environmental risk operates...
  71. ncbi request reprint A common genetic factor explains the association between psychopathic personality and antisocial behavior
    Henrik Larsson
    Social, Genetic, and Developmental Psychiatry Research Centre, Institute of Psychiatry, King s College London, UK
    Psychol Med 37:15-26. 2007
    ..However, little is known about how genetic and environmental factors contribute to the associations between the psychopathic personality traits and antisocial behavior...