Johanna T Lanner

Summary

Affiliation: Karolinska Institutet
Country: Sweden

Publications

  1. ncbi request reprint Effects of palmitate on Ca(2+) handling in adult control and ob/ob cardiomyocytes: impact of mitochondrial reactive oxygen species
    Jeremy Fauconnier
    Department of Physiology and Pharmacology, Karolinska Institutet, SE 171 77 Stockholm, Sweden
    Diabetes 56:1136-42. 2007
  2. doi request reprint Ryanodine receptor physiology and its role in disease
    Johanna T Lanner
    Department of Physiology and Pharmacology, Karolinska Institutet, Von Eulersväg 8, 171 77 Stockholm, Sweden
    Adv Exp Med Biol 740:217-34. 2012
  3. pmc Ca(2+) permeation and/or binding to CaV1.1 fine-tunes skeletal muscle Ca(2+) signaling to sustain muscle function
    Chang Seok Lee
    Department of Molecular Physiology and Biophysics, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030 USA
    Skelet Muscle 5:4. 2015
  4. doi request reprint Ca(2+) and insulin-mediated glucose uptake
    Johanna T Lanner
    Department of Physiology and Pharmacology, Karolinska Institutet, S 171 77 Stockholm, Sweden
    Curr Opin Pharmacol 8:339-45. 2008
  5. ncbi request reprint Insulin potentiates TRPC3-mediated cation currents in normal but not in insulin-resistant mouse cardiomyocytes
    Jeremy Fauconnier
    Department of Physiology and Pharmacology, Karolinska Institutet, SE 171 77 Stockholm, Sweden
    Cardiovasc Res 73:376-85. 2007
  6. ncbi request reprint The role of Ca2+ influx for insulin-mediated glucose uptake in skeletal muscle
    Johanna T Lanner
    Department of Physiology and Pharmacology, Karolinska Institutet, SE 171 77, Stockholm, Sweden
    Diabetes 55:2077-83. 2006
  7. ncbi request reprint Activation of aconitase in mouse fast-twitch skeletal muscle during contraction-mediated oxidative stress
    Shi Jin Zhang
    Dept of Physiology and Pharmacology, Karolinska Institutet, 171 77 Stockholm, Sweden
    Am J Physiol Cell Physiol 293:C1154-9. 2007
  8. doi request reprint Knockdown of TRPC3 with siRNA coupled to carbon nanotubes results in decreased insulin-mediated glucose uptake in adult skeletal muscle cells
    Johanna T Lanner
    Karolinska Institutet, Department of Physiology and Pharmacology, 171 77 Stockholm, Sweden
    FASEB J 23:1728-38. 2009
  9. pmc The Role of Reactive Oxygen Species in β-Adrenergic Signaling in Cardiomyocytes from Mice with the Metabolic Syndrome
    Monica Llano-Diez
    Karolinska Institutet, Department of Physiology and Pharmacology, Stockholm, Sweden
    PLoS ONE 11:e0167090. 2016
  10. ncbi request reprint Insulin and inositol 1,4,5-trisphosphate trigger abnormal cytosolic Ca2+ transients and reveal mitochondrial Ca2+ handling defects in cardiomyocytes of ob/ob mice
    Jeremy Fauconnier
    Department of Physiology and Pharmacology, Karolinska Institutet, SE 171 77 Stockholm, Sweden
    Diabetes 54:2375-81. 2005

Collaborators

Detail Information

Publications17

  1. ncbi request reprint Effects of palmitate on Ca(2+) handling in adult control and ob/ob cardiomyocytes: impact of mitochondrial reactive oxygen species
    Jeremy Fauconnier
    Department of Physiology and Pharmacology, Karolinska Institutet, SE 171 77 Stockholm, Sweden
    Diabetes 56:1136-42. 2007
    ..Conversely, high fatty acid levels may be vital to sustain cardiac Ca(2+) handling and contraction in obesity and insulin-resistant conditions...
  2. doi request reprint Ryanodine receptor physiology and its role in disease
    Johanna T Lanner
    Department of Physiology and Pharmacology, Karolinska Institutet, Von Eulersväg 8, 171 77 Stockholm, Sweden
    Adv Exp Med Biol 740:217-34. 2012
    ..This article discusses the physiological function of RyR and examines its role in disorders and diseases...
  3. pmc Ca(2+) permeation and/or binding to CaV1.1 fine-tunes skeletal muscle Ca(2+) signaling to sustain muscle function
    Chang Seok Lee
    Department of Molecular Physiology and Biophysics, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030 USA
    Skelet Muscle 5:4. 2015
    ..1 is not required for skeletal muscle excitation-contraction coupling, but whether Ca(2+) permeation through CaV1.1 during sustained muscle activity plays a functional role in mammalian skeletal muscle has not been assessed...
  4. doi request reprint Ca(2+) and insulin-mediated glucose uptake
    Johanna T Lanner
    Department of Physiology and Pharmacology, Karolinska Institutet, S 171 77 Stockholm, Sweden
    Curr Opin Pharmacol 8:339-45. 2008
    ..No Ca(2+) sensor in this process has yet been explicitly identified but recent studies point at synaptotagmin VII and the motor protein Myo1c as possible candidates...
  5. ncbi request reprint Insulin potentiates TRPC3-mediated cation currents in normal but not in insulin-resistant mouse cardiomyocytes
    Jeremy Fauconnier
    Department of Physiology and Pharmacology, Karolinska Institutet, SE 171 77 Stockholm, Sweden
    Cardiovasc Res 73:376-85. 2007
    ..In the present study we measured non-selective cation currents (NSCC) focusing on the interaction between insulin, the bioactive lipid diacylglycerol (DAG) and canonical transient receptor potential 3 (TRPC3) channels...
  6. ncbi request reprint The role of Ca2+ influx for insulin-mediated glucose uptake in skeletal muscle
    Johanna T Lanner
    Department of Physiology and Pharmacology, Karolinska Institutet, SE 171 77, Stockholm, Sweden
    Diabetes 55:2077-83. 2006
    ..Moreover, the present results indicate that Ca(2+) acts late in the insulin signaling pathway, for instance, in the GLUT4 translocation to the plasma membrane...
  7. ncbi request reprint Activation of aconitase in mouse fast-twitch skeletal muscle during contraction-mediated oxidative stress
    Shi Jin Zhang
    Dept of Physiology and Pharmacology, Karolinska Institutet, 171 77 Stockholm, Sweden
    Am J Physiol Cell Physiol 293:C1154-9. 2007
    ..During contraction, a ROS-mediated inactivation of aconitase can be overcome, possibly by dephosphorylation of the enzyme. The dual-control system may be important in maintaining aerobic ATP production during muscle contraction...
  8. doi request reprint Knockdown of TRPC3 with siRNA coupled to carbon nanotubes results in decreased insulin-mediated glucose uptake in adult skeletal muscle cells
    Johanna T Lanner
    Karolinska Institutet, Department of Physiology and Pharmacology, 171 77 Stockholm, Sweden
    FASEB J 23:1728-38. 2009
    ..Thus, TRPC3 is a potential target for treatment of insulin-resistant conditions...
  9. pmc The Role of Reactive Oxygen Species in β-Adrenergic Signaling in Cardiomyocytes from Mice with the Metabolic Syndrome
    Monica Llano-Diez
    Karolinska Institutet, Department of Physiology and Pharmacology, Stockholm, Sweden
    PLoS ONE 11:e0167090. 2016
    ..This can be seen as a beneficial adaptation to prevent excessive ROS levels...
  10. ncbi request reprint Insulin and inositol 1,4,5-trisphosphate trigger abnormal cytosolic Ca2+ transients and reveal mitochondrial Ca2+ handling defects in cardiomyocytes of ob/ob mice
    Jeremy Fauconnier
    Department of Physiology and Pharmacology, Karolinska Institutet, SE 171 77 Stockholm, Sweden
    Diabetes 54:2375-81. 2005
    ..This, together with an impaired mitochondrial Ca2+ handling, results in insulin-mediated extra Ca2+ transients in ob/ob cardiomyocytes that may predispose for arrhythmias in vivo...
  11. pmc Reactive oxygen/nitrogen species and contractile function in skeletal muscle during fatigue and recovery
    Arthur J Cheng
    Karolinska Institutet, Stockholm, SE 171 77, Sweden
    J Physiol 594:5149-60. 2016
    ....
  12. ncbi request reprint Antioxidant treatments do not improve force recovery after fatiguing stimulation of mouse skeletal muscle fibres
    Arthur J Cheng
    Department of Physiology and Pharmacology, Karolinska Institutet, 171 77 Stockholm, Sweden
    J Physiol . 2014
    ..The cocktail also increased resting [Ca2+]i and ultimately caused cell death. In conclusion, ROS/RNS-neutralizing compounds did not counteract the force decline during or after induction of fatigue...
  13. pmc Intracellular Ca(2+)-handling differs markedly between intact human muscle fibers and myotubes
    Karl Olsson
    Department of Laboratory Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, 141 86 Sweden Department of Physiology and Pharmacology, Karolinska Institutet, von Eulers v g 8, Stockholm, 171 77 Sweden
    Skelet Muscle 5:26. 2015
    ..Despite this, it is unknown whether the Ca(2+)-handling properties of myotubes adequately represent those of adult muscle fibers...
  14. pmc Nitrosative modifications of the Ca2+ release complex and actin underlie arthritis-induced muscle weakness
    Takashi Yamada
    Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden School of Health Sciences, Sapporo Medical University, Sapporo, Japan
    Ann Rheum Dis 74:1907-14. 2015
    ..Here we investigate the mechanisms behind arthritis-induced skeletal muscle weakness with special focus on the role of nitrosative stress on intracellular Ca(2+) handling and specific force production...
  15. pmc Antioxidant treatments do not improve force recovery after fatiguing stimulation of mouse skeletal muscle fibres
    Arthur J Cheng
    Department of Physiology and Pharmacology, Karolinska Institutet, 171 77 Stockholm, Sweden
    J Physiol 593:457-72. 2015
    ..The cocktail also increased resting [Ca(2+) ]i and ultimately caused cell death. In conclusion, ROS/RNS-neutralizing compounds did not counteract the force decline during or after induction of fatigue...
  16. doi request reprint Dietary nitrate markedly improves voluntary running in mice
    Niklas Ivarsson
    Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden Electronic address
    Physiol Behav 168:55-61. 2017
    ..In conclusion, low-frequency force improvement due to nitrate supplementation facilitates submaximal exercise such as voluntary running...
  17. pmc The role of arginase and rho kinase in cardioprotection from remote ischemic perconditioning in non-diabetic and diabetic rat in vivo
    Attila Kiss
    Division of Cardiology, Department of Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden
    PLoS ONE 9:e104731. 2014
    ..Pharmacological inhibition of arginase and remote ischemic perconditioning (RIPerc) are known to protect the heart against ischemia/reperfusion (IR) injury...