Mikael Landen

Summary

Affiliation: Karolinska Institutet
Country: Sweden

Publications

  1. ncbi Incidence of sexual side effects in refractory depression during treatment with citalopram or paroxetine
    Mikael Landen
    Section of Psychiatry St Göran, Department of Clinical Neuroscience, Karolinska Institutet, SE 112 81, Stockholm, Sweden
    J Clin Psychiatry 66:100-6. 2005
  2. ncbi Placebo-controlled trial comparing intermittent and continuous paroxetine in premenstrual dysphoric disorder
    Mikael Landen
    Department of Clinical Neuroscience, Section of Psychiatry St Göran, Karolinska Institutet, Stockholm, Sweden
    Neuropsychopharmacology 32:153-61. 2007
  3. ncbi [Affective disorders differ in women and men. Not only prevalence but also symptoms and treatment outcome seem to be different]
    Mikael Landen
    Karolinska Institutet, sektionen för psykiatri S t Göran, Stockholm
    Lakartidningen 104:29-31. 2007
  4. doi Short onset of action of a serotonin reuptake inhibitor when used to reduce premenstrual irritability
    Mikael Landen
    Department of Clinical Neuroscience, Section of Psychiatry S t Göran, Karolinska Institutet, Stockholm, Sweden
    Neuropsychopharmacology 34:585-92. 2009
  5. pmc Cognitive manic symptoms in bipolar disorder associated with polymorphisms in the DAOA and COMT genes
    Dzana Sudic Hukic
    Neurogenetics Unit, Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden
    PLoS ONE 8:e67450. 2013
  6. pmc P2RX7: expression responds to sleep deprivation and associates with rapid cycling in bipolar disorder type 1
    Lena Backlund
    Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
    PLoS ONE 7:e43057. 2012
  7. doi The societal cost of bipolar disorder in Sweden
    Mattias Ekman
    OptumInsight, Stockholm, Sweden
    Soc Psychiatry Psychiatr Epidemiol 48:1601-10. 2013
  8. doi Kynurenic acid and psychotic symptoms and personality traits in twins with psychiatric morbidity
    Magdalena E Kegel
    Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden
    Psychiatry Res 247:105-112. 2016
  9. ncbi The Risk of Treatment-Emergent Mania With Methylphenidate in Bipolar Disorder
    Alexander Viktorin
    From the Department of Medical Epidemiology and Biostatistics and the Department of Clinical Neuroscience, Karolinska Institutet, Stockholm the Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York the Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia the Department of Psychological and Brain Sciences, Indiana University, Bloomington Astrid Lindgren Children s Hospital, Karolinska University Hospital, Stockholm the Department of Medical Sciences, Orebro University, Orebro, Sweden and the Institute of Neuroscience and Physiology, University of Gothenburg, Gothenburg, Sweden
    Am J Psychiatry . 2016
  10. pmc Risk of bipolar disorder and schizophrenia in relatives of people with attention-deficit hyperactivity disorder
    Henrik Larsson
    Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden
    Br J Psychiatry 203:103-6. 2013

Detail Information

Publications50

  1. ncbi Incidence of sexual side effects in refractory depression during treatment with citalopram or paroxetine
    Mikael Landen
    Section of Psychiatry St Göran, Department of Clinical Neuroscience, Karolinska Institutet, SE 112 81, Stockholm, Sweden
    J Clin Psychiatry 66:100-6. 2005
    ....
  2. ncbi Placebo-controlled trial comparing intermittent and continuous paroxetine in premenstrual dysphoric disorder
    Mikael Landen
    Department of Clinical Neuroscience, Section of Psychiatry St Göran, Karolinska Institutet, Stockholm, Sweden
    Neuropsychopharmacology 32:153-61. 2007
    ..Symptoms such as irritability, affect lability, and mood swings appear to be more inclined to respond rapidly to SRIs, enabling intermittent treatment, than are, for example, the somatic symptoms...
  3. ncbi [Affective disorders differ in women and men. Not only prevalence but also symptoms and treatment outcome seem to be different]
    Mikael Landen
    Karolinska Institutet, sektionen för psykiatri S t Göran, Stockholm
    Lakartidningen 104:29-31. 2007
  4. doi Short onset of action of a serotonin reuptake inhibitor when used to reduce premenstrual irritability
    Mikael Landen
    Department of Clinical Neuroscience, Section of Psychiatry S t Göran, Karolinska Institutet, Stockholm, Sweden
    Neuropsychopharmacology 34:585-92. 2009
    ..To summarize, this controlled trial shows that an SRI reduces premenstrual irritability already within a few days after the onset of treatment...
  5. pmc Cognitive manic symptoms in bipolar disorder associated with polymorphisms in the DAOA and COMT genes
    Dzana Sudic Hukic
    Neurogenetics Unit, Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden
    PLoS ONE 8:e67450. 2013
    ..Dopamine and glutamate are important for cognitive processing, thus the COMT and DAOA genes that modulate the expression of these neurotransmitters are of interest for studies of cognitive function...
  6. pmc P2RX7: expression responds to sleep deprivation and associates with rapid cycling in bipolar disorder type 1
    Lena Backlund
    Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
    PLoS ONE 7:e43057. 2012
    ..We hypothesized that the P2RX7 gene would be affected by sleep deprivation and be implicated in rapid cycling...
  7. doi The societal cost of bipolar disorder in Sweden
    Mattias Ekman
    OptumInsight, Stockholm, Sweden
    Soc Psychiatry Psychiatr Epidemiol 48:1601-10. 2013
    ..The purpose of this study was to estimate the societal cost of bipolar disorder and to relate costs to disease severity, depressive episodes, hospitalisation and patient functioning...
  8. doi Kynurenic acid and psychotic symptoms and personality traits in twins with psychiatric morbidity
    Magdalena E Kegel
    Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden
    Psychiatry Res 247:105-112. 2016
    ..Intraclass correlations indicated genetic influences on CSF KYNA, TRP, IL-8 and TNF-α. The association between KYNA and psychotic symptoms further supports a role of KYNA in psychotic disorders...
  9. ncbi The Risk of Treatment-Emergent Mania With Methylphenidate in Bipolar Disorder
    Alexander Viktorin
    From the Department of Medical Epidemiology and Biostatistics and the Department of Clinical Neuroscience, Karolinska Institutet, Stockholm the Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York the Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia the Department of Psychological and Brain Sciences, Indiana University, Bloomington Astrid Lindgren Children s Hospital, Karolinska University Hospital, Stockholm the Department of Medical Sciences, Orebro University, Orebro, Sweden and the Institute of Neuroscience and Physiology, University of Gothenburg, Gothenburg, Sweden
    Am J Psychiatry . 2016
    ..The authors sought to determine the risk of treatment-emergent mania associated with methylphenidate, used in monotherapy or with a concomitant mood-stabilizing medication, in patients with bipolar disorder...
  10. pmc Risk of bipolar disorder and schizophrenia in relatives of people with attention-deficit hyperactivity disorder
    Henrik Larsson
    Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden
    Br J Psychiatry 203:103-6. 2013
    ..Attention-deficit hyperactivity disorder (ADHD) is associated with bipolar disorder and schizophrenia, and it has been suggested that combined bipolar disorder and ADHD is aetiologically distinct from the pure disorders...
  11. doi Mental illness, suicide and creativity: 40-year prospective total population study
    Simon Kyaga
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Box 281, 171 77 Stockholm, Sweden
    J Psychiatr Res 47:83-90. 2013
    ..We discuss the findings in relationship to some of the major components of creativity...
  12. doi Polymorphisms in AKR1C4 and HSD3B2 and differences in serum DHEAS and progesterone are associated with paranoid ideation during mania or hypomania in bipolar disorder
    Anette G M Johansson
    Division of Psychiatry, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
    Eur Neuropsychopharmacol 22:632-40. 2012
    ..31 (95% CI 0.10-0.96)) but did not correlate with hormone concentrations. Hence, gene variants in the steroidogenetic pathway and steroids concentration differences may be involved in the susceptibility to paranoia during mood elevation...
  13. doi Cerebrospinal fluid microglia and neurodegenerative markers in twins concordant and discordant for psychotic disorders
    Viktoria Johansson
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    Eur Arch Psychiatry Clin Neurosci . 2016
    ..The study provides support for a significant role of sCD14 in psychotic disorders and a possible role of microglia activation in psychosis...
  14. doi Microparticles and microscopic structures in three fractions of fresh cerebrospinal fluid in schizophrenia: case report of twins
    Fariborz Mobarrez
    Karolinska Institutet, Department of Clinical Sciences, Danderyd Hospital, Division of Cardiovascular Medicine, Stockholm, Sweden
    Schizophr Res 143:192-7. 2013
    ..Such MPs can be investigated for both human and non-human DNA, RNA and microRNA that may activate different immune signaling systems in patients with schizophrenia...
  15. doi The neural correlates of self-paced finger tapping in bipolar depression with motor retardation
    Benny Liberg
    1 Department of Clinical Neuroscience, Division of Psychiatry, Karolinska Institutet, Stockholm, Sweden
    Acta Neuropsychiatr 25:43-51. 2013
    ....
  16. doi Congenital adrenal hyperplasia and risk for psychiatric disorders in girls and women born between 1915 and 2010: A total population study
    Hedvig Engberg
    Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden Child and Adolescent Psychiatry Research Center, Stockholm, Sweden Electronic address
    Psychoneuroendocrinology 60:195-205. 2015
    ..Prenatal androgen exposure and deficient endogenous cortisol and/or adrenaline production may provide explanations for these findings, but other factors related to CAH cannot be excluded...
  17. doi Selective serotonin re-uptake inhibitor use during pregnancy: association with offspring birth size and gestational age
    Alexander Viktorin
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    Int J Epidemiol 45:170-7. 2016
    ..We aimed to examine the effects of prenatal SSRI exposure on offspring size outcomes and gestational age, and disentangle whether associations observed were due to the medication or other factors...
  18. pmc A History of Psychosis in Bipolar Disorder is Associated With Gray Matter Volume Reduction
    Carl Johan Ekman
    Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
    Schizophr Bull . 2016
    ..These areas have previously been structurally and functionally coupled to delusions and hallucinations. Our finding adds further evidence to the probability of these regions as key areas in the development of psychotic symptoms...
  19. pmc Cortical thickness, volume and surface area in patients with bipolar disorder types I and II
    Christoph Abé
    From the Departments of Clinical Neuroscience Abé, Ekman, Petrovic, Ingvar, Landén, Physiology and Pharmacology Sellgren, and Medical Epidemiology and Biostatistics Landén, Karolinska Institutet, Stockholm, Sweden and the Institute of Neuroscience and Physiology, the Sahlgrenska Academy at the Gothenburg University, Gothenburg, Sweden Landén
    J Psychiatry Neurosci 41:240-50. 2016
    ..The aim of our study was to investigate abnormalities in patients with BDI and BDII by simultaneously analyzing cortical volume, thickness and surface area, which yields more information about disease- and symptom-related neurobiology...
  20. doi Hypospadias and increased risk for neurodevelopmental disorders
    Agnieszka Butwicka
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden Department of Child Psychiatry, Medical University of Warsaw, Warsaw, Poland
    J Child Psychol Psychiatry 56:155-61. 2015
    ..To elucidate the mechanisms behind a possible association, we also studied psychiatric outcomes among brothers of the hypospadias patients...
  21. doi Increased psychiatric morbidity in men with congenital adrenal hyperplasia due to 21-hydroxylase deficiency
    Henrik Falhammar
    Department of Endocrinology, Metabolism, and Diabetes H F, Karolinska University Hospital, SE 171 76 Stockholm, Sweden Departments of Molecular Medicine and Surgery H F, An N, and Medical Epidemiology and Biostatistics A B, M L, P L, Karolinska Institutet, SE 171 77 Stockholm, Sweden Department of Child Psychiatry A B, Medical University of Warsaw, 02 091 Warsaw, Poland Institute of Neuroscience and Physiology M L, University of Gothenburg, SE 405 30 Gothenburg, Sweden Department of Women s and Children s Health and Center for Molecular Medicine Ag N, Karolinska Institutet, SE 171 77 Stockholm, Sweden Departments of Pediatric Surgery Ag N, and Pediatric Endocrinology An N, Astrid Lindgren Children Hospital, Karolinska University Hospital, SE 171 76 Stockholm, Sweden Department of Clinical Neuroscience L F, Karolinska Institutet, SE 171 77 Stockholm, Sweden and Child and Adolescent Psychiatry Research Center L F, SE 11330 Stockholm, Sweden
    J Clin Endocrinol Metab 99:E554-60. 2014
    ..Reports on psychiatric morbidity in males with congenital adrenal hyperplasia (CAH) are lacking...
  22. doi Acute intermittent porphyria: comorbidity and shared familial risks with schizophrenia and bipolar disorder in Sweden
    Martin Cederlöf
    Martin Cederlöf, MSc, Sarah E Bergen, PhD, Henrik Larsson, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm Mikael Landén, MD, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm and Institute of Neuroscience and Physiology, University of Gothenburg, Gothenburg, Sweden Paul Lichtenstein, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    Br J Psychiatry 207:556-7. 2015
    ..Similarly, relatives of individuals with AIP had double the risk of schizophrenia or bipolar disorder, suggesting that these associations may be as a result of common genetic influences. ..
  23. pmc Obsessive-Compulsive Disorder, Psychosis, and Bipolarity: A Longitudinal Cohort and Multigenerational Family Study
    Martin Cederlöf
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    Schizophr Bull 41:1076-83. 2015
    ..We conclude that OCD is etiologically related to both schizophrenia spectrum and bipolar disorders. The results have implications for current gene-searching efforts and for clinical practice...
  24. pmc Significant grey matter changes in a region of the orbitofrontal cortex in healthy participants predicts emotional dysregulation
    Predrag Petrovic
    Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
    Soc Cogn Affect Neurosci 11:1041-9. 2016
    ..Our findings support the concept of continuous properties in psychiatric symptomatology. ..
  25. doi Subcortical morphometry and psychomotor function in euthymic bipolar disorder with a history of psychosis
    Benny Liberg
    Department of Clinical Neuroscience, Division of Psychiatry, Karolinska Institutet, Stockholm, Sweden
    Brain Imaging Behav 9:333-41. 2015
    ....
  26. doi The association between Darier disease, bipolar disorder, and schizophrenia revisited: a population-based family study
    Martin Cederlöf
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    Bipolar Disord 17:340-4. 2015
    ..It is, however, unknown whether these associations exist also in the general population, and the objective of this study was to examine this question...
  27. doi Multiple sclerosis and psychiatric disorders: comorbidity and sibling risk in a nationwide Swedish cohort
    Viktoria Johansson
    Karolinska Institutet, Stockholm, Sweden
    Mult Scler 20:1881-91. 2014
    ..Psychiatric disorders are known to be prevalent in multiple sclerosis (MS)...
  28. doi Vertex-based morphometry in euthymic bipolar disorder implicates striatal regions involved in psychomotor function
    Benny Liberg
    Department of Clinical Neuroscience, Division of Psychiatry, Karolinska Institutet, Stockholm, Sweden Electronic address
    Psychiatry Res 221:173-8. 2014
    ..It may be that other brain regions sustain the psychomotor functions that produce nearly identical motor performance in both groups. ..
  29. pmc Microscopic particles in two fractions of fresh cerebrospinal fluid in twins with schizophrenia or bipolar disorder and in healthy controls
    Viktoria Johansson
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    PLoS ONE 7:e45994. 2012
    ..This question can be addressed by studying twins discordant or concordant for schizophrenia or bipolar disorder...
  30. doi Cognitive manic symptoms associated with the P2RX7 gene in bipolar disorder
    Lena Backlund
    Department of Clinical Neuroscience Neurogenetics Unit, Department of Molecular Medicine and Surgery, Karolinska Institutet, Karolinska University Hospital, Huddinge, Stockholm, Sweden
    Bipolar Disord 13:500-8. 2011
    ..Studying associations between bipolar symptoms and candidate genes may better expose this relationship. Here we investigate the association between bipolar key symptoms and the P2RX7 gene...
  31. doi Pharmacological treatment and risk of psychiatric hospital admission in bipolar disorder
    Erik Joas
    Erik Joas, MSc, Alina Karanti, MD, Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden Jie Song, MSc, Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden Guy M Goodwin, FMedSci, Department of Psychiatry, University of Oxford, Warneford Hospital, Oxford, UK Paul Lichtenstein, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden Mikael Landén MD, PhD, Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry, The Sahlgrenska Academy, University of Gothenburg, Gothenburg and Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    Br J Psychiatry . 2017
    ..Clinical trials have examined the efficacy of drugs to prevent relapse in patients with bipolar disorder, however, their design often limits generalisation to routine clinical practice...
  32. doi Manic episodes are related to changes in frontal cortex: a longitudinal neuroimaging study of bipolar disorder 1
    Christoph Abé
    1 Department of Clinical Neuroscience, Osher Center, Karolinska Institutet, Stockholm, Sweden
    Brain 138:3440-8. 2015
    ..Our results indicate that volume decrease in frontal brain regions can be attributed to the incidence of manic episodes. ..
  33. pmc Electroconvulsive therapy suppresses the neurotoxic branch of the kynurenine pathway in treatment-resistant depressed patients
    Lilly Schwieler
    Department of Physiology and Pharmacology, Karolinska Institutet, SE 171 77, Stockholm, Sweden
    J Neuroinflammation 13:51. 2016
    ....
  34. pmc Impact of a cis-associated gene expression SNP on chromosome 20q11.22 on bipolar disorder susceptibility, hippocampal structure and cognitive performance
    Ming Li
    Ming Li, PhD, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China, and Lieber Institute for Brain Development, Johns Hopkins University, Baltimore, Maryland, USA Xiong jian Luo, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China Mikael Landén, MD, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, and Section of Psychiatry and Neurochemistry, Sahlgrenska Academy at Gothenburg University, Gothenburg, Sweden Sarah E Bergen, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden, and Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA Christina M Hultman, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden Xiao Li, MSc, Wen Zhang
    Br J Psychiatry 208:128-37. 2016
    ..Bipolar disorder is a highly heritable polygenic disorder. Recent enrichment analyses suggest that there may be true risk variants for bipolar disorder in the expression quantitative trait loci (eQTL) in the brain...
  35. doi Heritability of Perinatal Depression and Genetic Overlap With Nonperinatal Depression
    Alexander Viktorin
    From the Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm the Departments of Psychiatry and Genetics, University of North Carolina School of Medicine, Chapel Hill and the Institute of Neuroscience and Physiology, University of Gothenburg, Gothenburg, Sweden
    Am J Psychiatry 173:158-65. 2016
    ..The authors investigated the relative importance of genetic and environmental influences on perinatal depression, and the genetic overlap between perinatal depression and nonperinatal depression...
  36. doi Bipolar disorder and its relation to major psychiatric disorders: a family-based study in the Swedish population
    Jie Song
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm
    Bipolar Disord 17:184-93. 2015
    ....
  37. pmc The association between schizophrenia and rheumatoid arthritis: a nationwide population-based Swedish study on intraindividual and familial risks
    Carl Sellgren
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    Schizophr Bull 40:1552-9. 2014
    ..Our familial analyses indicted the possibility of an inverse coinheritance of schizophrenia and seronegative RA. ..
  38. doi The Roots of Autism and ADHD Twin Study in Sweden (RATSS)
    Sven Bolte
    Center of Neurodevelopmental Disorders at Karolinska Institutet, Pediatric Neuropsychiatry Unit, Department of Women s and Children s Health, Karolinska Institutet, Stockholm, Sweden
    Twin Res Hum Genet 17:164-76. 2014
    ..Potential gains of the study comprise the identification of environmentally mediated biomarkers, the emergence of candidates for drug development, translational modeling, and new leads for prevention of incapacitating outcomes. ..
  39. ncbi The societal cost of schizophrenia in Sweden
    Mattias Ekman
    Health Economics and Outcomes Research, OptumInsight, Stockholm, Sweden
    J Ment Health Policy Econ 16:13-25. 2013
    ..Existing cost estimates for Sweden, however, are based on relatively small patient populations and need to be confirmed in a large register-based study...
  40. doi Cerebrospinal fluid kynurenic acid is associated with manic and psychotic features in patients with bipolar I disorder
    Sara K Olsson
    Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden
    Bipolar Disord 14:719-26. 2012
    ..Here, we investigate the relationship between symptomatology and the concentration of CSF KYNA in patients with bipolar I disorder...
  41. pmc Leukocyte-derived microparticles and scanning electron microscopic structures in two fractions of fresh cerebrospinal fluid in amyotrophic lateral sclerosis: a case report
    Anne C Zachau
    Karolinska Institutet, Department of Clinical Neuroscience at St, Göran, Stockholm, Sweden
    J Med Case Rep 6:274. 2012
    ..This is the first report to our knowledge of microparticles in the cerebrospinal fluid of a patient with amyotrophic lateral sclerosis...
  42. doi Creativity and mental disorder: family study of 300,000 people with severe mental disorder
    Simon Kyaga
    Department of Epidemiology and Biostatistics, Karolinska Institutet, POB 281, SE 171 77 Stockholm, Sweden
    Br J Psychiatry 199:373-9. 2011
    ..There is a long-standing belief that creativity is coupled with psychopathology...
  43. ncbi Subjective Memory Immediately Following Electroconvulsive Therapy
    Ole Brus
    From the Clinical Epidemiology and Biostatistics, School of Medical Sciences, Orebro University, Örebro Center for Social and Affective Neuroscience, Department of Clinical and Experimental Medicine, Faculty of Health Sciences, Linkoping University, Linköping Department of Psychiatry, Region Östergötland, Linköping Department of Clinical Neuroscience, and Unit of Biostatistics, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden Department of Biological and Medical Psychology, University of Bergen, Bergen Division of Psychiatry, Haukeland University Hospital, Bergen, Norway Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm Institute of Neuroscience and Physiology, The Sahlgrenska Academy at Gothenburg University, Gothenburg Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm and School of Medical Sciences, Orebro University, Orebro, Sweden
    J ECT . 2016
    ..The aims of the present study were to describe the short-term rate of subjective memory worsening (SMW) and identify factors of importance for SMW in a large clinical sample treated for depression with electroconvulsive therapy (ECT)...
  44. doi CACNA1C polymorphism and altered phosphorylation of tau in bipolar disorder
    Joel Jakobsson
    Joel Jakobsson, PhD, Erik Pålsson, PhD, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden Carl Sellgren, PhD, MD, Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden Frida Rydberg, MD, Agneta Ekman, PhD, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden Henrik Zetterberg, PhD, MD, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden and UCL Institute of Neurology, London, UK Kaj Blennow, PhD, MD, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden Mikael Landén, PhD, MD, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg
    Br J Psychiatry 208:195-6. 2016
    ....
  45. doi Motor imagery in bipolar depression with slowed movement
    Benny Liberg
    Department of Clinical Neuroscience, Division of Psychiatry, Karolinska Institutet, Stockholm, Sweden Department of Diagnostic Medical Physics, Karolinska University Hospital Huddinge, Stockholm, Sweden Institute of Neuroscience and Physiology, University of Gothenburg, Gothenburg, Sweden Department NVS, Division of Clinical Geriatrics, Karolinska University Hospital, Stockholm, Sweden Department of Clinical Science, Intervention and Technology, Division of Radiology, Karolinska Institutet, Stockholm, Sweden and Department of Energy and Engineering, Swedish University of Agricultural Sciences, Uppsala, Sweden
    J Nerv Ment Dis 201:885-93. 2013
    ..In addition, limbic and prefrontal regions associated with self-reference and the default mode network were altered during motor imagery in bipolar depression with motor retardation. ..
  46. pmc Serotonin transporter occupancy with TCAs and SSRIs: a PET study in patients with major depressive disorder
    Johan Lundberg
    Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
    Int J Neuropsychopharmacol 15:1167-72. 2012
    ..5-HTT affinity correlated with the recommended clinical dose. Mirtazapine did not occupy the serotonin transporter. The results support that TCAs and SSRIs have a shared mechanism of action by inhibition of 5-HTT...
  47. doi Sex steroids, insulin sensitivity and sympathetic nerve activity in relation to affective symptoms in women with polycystic ovary syndrome
    Elizabeth Jedel
    Osher Center for Integrative Medicine, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
    Psychoneuroendocrinology 36:1470-9. 2011
    ..Further, PCOS is associated with high sympathetic nerve activity...
  48. doi AKR1C4 gene variant associated with low euthymic serum progesterone and a history of mood irritability in males with bipolar disorder
    Anette G M Johansson
    Division of Psychiatry, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
    J Affect Disord 133:346-51. 2011
    ....
  49. doi Children's Global Assessment Scale (CGAS) in a naturalistic clinical setting: Inter-rater reliability and comparison with expert ratings
    Anna Lundh
    Section of Psychiatry, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
    Psychiatry Res 177:206-10. 2010
    ..Further, the untrained raters differed substantially from the experts. This stresses the importance of proper training in conjunction with the introduction of new rating scales...
  50. doi Lower CSF HVA and 5-HIAA in bipolar disorder type 1 with a history of childhood ADHD
    Eleonore Rydén
    Section of Psychiatry, Department of Clinical Neuroscience, Karolinska Institutet, 171 77 Stockholm, Sweden
    J Neural Transm (Vienna) 116:1667-74. 2009
    ..This lends biological support to the notion that those with childhood ADHD represent a valid subphenotype of bipolar disorder...