Jussi Jokinen

Summary

Affiliation: Karolinska Institutet
Country: Sweden

Publications

  1. pmc Low vascular endothelial growth factor and interleukin-8 in cerebrospinal fluid of suicide attempters
    J Isung
    Department of Clinical Neuroscience, Karolinska Institute, Stockholm, Sweden
    Transl Psychiatry 2:e196. 2012
  2. doi request reprint Low CSF oxytocin reflects high intent in suicide attempters
    Jussi Jokinen
    The Department of Clinical Neuroscience Psychiatry, Karolinska Institutet, Karolinska University Hospital, Solna, SE 171 76 Stockholm, Sweden
    Psychoneuroendocrinology 37:482-90. 2012
  3. ncbi request reprint CSF 5-HIAA and DST non-suppression -independent biomarkers in suicide attempters?
    Jussi Jokinen
    Department of Clinical Neuroscience, Psychiatry Section, Karolinska Institutet, Karolinska University Hospital, Solna, SE 171 76 Stockholm, Sweden
    J Affect Disord 105:241-5. 2008
  4. ncbi request reprint ROC analysis of dexamethasone suppression test threshold in suicide prediction after attempted suicide
    Jussi Jokinen
    Department of Clinical Neuroscience, Psychiatry Section, Karolinska Institutet, Karolinska University Hospital, Solna, SE 171 76 Stockholm, Sweden
    J Affect Disord 106:145-52. 2008
  5. doi request reprint HPT axis, CSF monoamine metabolites, suicide intent and depression severity in male suicide attempters
    Jussi Jokinen
    Department of Clinical Neuroscience Psychiatry, Karolinska Institutet, Karolinska University Hospital, Solna, SE 171 76 Stockholm, Sweden
    J Affect Disord 111:119-24. 2008
  6. doi request reprint HPA axis hyperactivity as suicide predictor in elderly mood disorder inpatients
    Jussi Jokinen
    Department of Clinical Neuroscience Psychiatry, Karolinska Institutet, Karolinska University Hospital, Solna, SE 171 76 Stockholm, Sweden
    Psychoneuroendocrinology 33:1387-93. 2008
  7. doi request reprint Cerebrospinal fluid monoamine metabolites and suicide
    Jussi Jokinen
    Department of Clinical Neuroscience, Psychiatry Section, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden
    Nord J Psychiatry 63:276-9. 2009
  8. doi request reprint HPA axis hyperactivity and cardiovascular mortality in mood disorder inpatients
    Jussi Jokinen
    Department of Clinical Neuroscience Psychiatry, Karolinska Institutet, Karolinska University Hospital, Solna, SE 171 76 Stockholm, Sweden
    J Affect Disord 116:88-92. 2009
  9. doi request reprint HPA axis hyperactivity and attempted suicide in young adult mood disorder inpatients
    Jussi Jokinen
    Department of Clinical Neuroscience Psychiatry, Karolinska Institutet, Karolinska University Hospital, Solna, SE 171 76 Stockholm, Sweden
    J Affect Disord 116:117-20. 2009
  10. doi request reprint CSF 5-HIAA and DST non-suppression--orthogonal biologic risk factors for suicide in male mood disorder inpatients
    Jussi Jokinen
    Department of Clinical Neuroscience, Psychiatry Section, Karolinska Institutet, Karolinska University Hospital, Solna, SE 171 76 Stockholm, Sweden
    Psychiatry Res 165:96-102. 2009

Collaborators

Detail Information

Publications46

  1. pmc Low vascular endothelial growth factor and interleukin-8 in cerebrospinal fluid of suicide attempters
    J Isung
    Department of Clinical Neuroscience, Karolinska Institute, Stockholm, Sweden
    Transl Psychiatry 2:e196. 2012
    ..The results support a role for an impaired innate immunity and dysregulation of neuroprotection in the pathophysiology of depression and suicidal behavior...
  2. doi request reprint Low CSF oxytocin reflects high intent in suicide attempters
    Jussi Jokinen
    The Department of Clinical Neuroscience Psychiatry, Karolinska Institutet, Karolinska University Hospital, Solna, SE 171 76 Stockholm, Sweden
    Psychoneuroendocrinology 37:482-90. 2012
    ..Oxytocin levels did not differ significantly in suicide victims compared to survivors. CSF oxytocin may be an important modulator of suicide intent and interpersonal violence in suicide attempters...
  3. ncbi request reprint CSF 5-HIAA and DST non-suppression -independent biomarkers in suicide attempters?
    Jussi Jokinen
    Department of Clinical Neuroscience, Psychiatry Section, Karolinska Institutet, Karolinska University Hospital, Solna, SE 171 76 Stockholm, Sweden
    J Affect Disord 105:241-5. 2008
    ..Previous suicide attempt is the most robust clinical risk factor...
  4. ncbi request reprint ROC analysis of dexamethasone suppression test threshold in suicide prediction after attempted suicide
    Jussi Jokinen
    Department of Clinical Neuroscience, Psychiatry Section, Karolinska Institutet, Karolinska University Hospital, Solna, SE 171 76 Stockholm, Sweden
    J Affect Disord 106:145-52. 2008
    ..3 microg/dl) changed the Odds ratio from 6.7 till 18. In female suicide attempters a higher threshold (7.3 microg/dl) optimised the value of DST as a biological test for suicide prediction indicating a gender difference...
  5. doi request reprint HPT axis, CSF monoamine metabolites, suicide intent and depression severity in male suicide attempters
    Jussi Jokinen
    Department of Clinical Neuroscience Psychiatry, Karolinska Institutet, Karolinska University Hospital, Solna, SE 171 76 Stockholm, Sweden
    J Affect Disord 111:119-24. 2008
    ..Dopaminergic regulatory mechanisms on the thyroid hormone activity may be altered in male suicide attempters...
  6. doi request reprint HPA axis hyperactivity as suicide predictor in elderly mood disorder inpatients
    Jussi Jokinen
    Department of Clinical Neuroscience Psychiatry, Karolinska Institutet, Karolinska University Hospital, Solna, SE 171 76 Stockholm, Sweden
    Psychoneuroendocrinology 33:1387-93. 2008
    ....
  7. doi request reprint Cerebrospinal fluid monoamine metabolites and suicide
    Jussi Jokinen
    Department of Clinical Neuroscience, Psychiatry Section, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden
    Nord J Psychiatry 63:276-9. 2009
    ..In violent suicides, CSF 5-HIAA levels were negatively correlated with SIS. Greater suicide intent may be associated with greater aggressive intent and predicts a violent suicide method...
  8. doi request reprint HPA axis hyperactivity and cardiovascular mortality in mood disorder inpatients
    Jussi Jokinen
    Department of Clinical Neuroscience Psychiatry, Karolinska Institutet, Karolinska University Hospital, Solna, SE 171 76 Stockholm, Sweden
    J Affect Disord 116:88-92. 2009
    ....
  9. doi request reprint HPA axis hyperactivity and attempted suicide in young adult mood disorder inpatients
    Jussi Jokinen
    Department of Clinical Neuroscience Psychiatry, Karolinska Institutet, Karolinska University Hospital, Solna, SE 171 76 Stockholm, Sweden
    J Affect Disord 116:117-20. 2009
    ..The impact of age related changes in HPA-axis system activity in relation to suicidal behaviour across the lifecycle may be of importance...
  10. doi request reprint CSF 5-HIAA and DST non-suppression--orthogonal biologic risk factors for suicide in male mood disorder inpatients
    Jussi Jokinen
    Department of Clinical Neuroscience, Psychiatry Section, Karolinska Institutet, Karolinska University Hospital, Solna, SE 171 76 Stockholm, Sweden
    Psychiatry Res 165:96-102. 2009
    ..CSF 5-HIAA is associated with short-term suicide risk; dysregulation of the hypothalamic-pituitary-adrenal axis seems to be a long-term suicide predictor...
  11. doi request reprint Karolinska Interpersonal Violence Scale predicts suicide in suicide attempters
    Jussi Jokinen
    Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
    J Clin Psychiatry 71:1025-32. 2010
    ....
  12. doi request reprint Noradrenergic function and HPA axis dysregulation in suicidal behaviour
    Jussi Jokinen
    Department of Clinical Neuroscience, Psychiatry Section, Karolinska Institutet, Karolinska University Hospital, Solna, SE 171 76 Stockholm, Sweden
    Psychoneuroendocrinology 35:1536-42. 2010
    ..88. In conclusion, lower CSF MHPG was associated with suicide risk. Furthermore these results suggest that combined measures of noradrenergic system and HPA axis function may offer better prediction of suicide risk...
  13. doi request reprint Cholesterol, CSF 5-HIAA, violence and intent in suicidal men
    Jussi Jokinen
    Department of Clinical Neuroscience Psychiatry, Karolinska Institutet, Karolinska University Hospital, Solna, Stockholm, Sweden
    Psychiatry Res 178:217-9. 2010
    ..A positive association was observed between CSF 5-HIAA and serum cholesterol in suicides. The role of cholesterol may be different in planned non-violent suicide attempts compared with violent suicide attempts...
  14. doi request reprint CSF 5-HIAA, cortisol and DHEAS levels in suicide attempters
    Andreas Chatzittofis
    Department of Clinical Neuroscience Psychiatry, Karolinska Institutet, Karolinska University Hospital, Solna, SE 171 76 Stockholm, Sweden
    Eur Neuropsychopharmacol 23:1280-7. 2013
    ..The results underlie the important role of the serotonergic system and HPA axis in suicidal behaviour and suggest that CSF DHEAS may be elevated in male suicide attempters. ..
  15. doi request reprint Early death and CSF monoamine metabolites in schizophrenia spectrum psychosis
    Andreas Carlborg
    Department of Clinical Neuroscience, Psychiatry, Karolinska Institutet, Karolinska University Hospital, Solna, Sweden
    Nord J Psychiatry 65:101-5. 2011
    ....
  16. ncbi request reprint DST non-suppression predicts suicide after attempted suicide
    Jussi Jokinen
    Department of Clinical Neuroscience, Psychiatry Section, Karolinska Institutet Karolinska University Hospital, Solna, SE 171 76 Stockholm, Sweden
    Psychiatry Res 150:297-303. 2007
    ..The dexamethasone suppression test may be a useful predictor within this population...
  17. doi request reprint Attempted suicide predicts suicide risk in schizophrenia spectrum psychosis
    Andreas Carlborg
    Department of Clinical Neuroscience, Psychiatry, Karolinska Institutet, Karolinska University Hospital, Solna, Sweden
    Nord J Psychiatry 64:68-72. 2010
    ..People with schizophrenia have an increased risk of suicide and attempted suicide is suggested to be an important risk factor...
  18. doi request reprint Suicide risk after homicide in Sweden
    Jussi Jokinen
    Department of Clinical Neuroscience, Karolinska Institutet, Karolinska University Hospital, Solna, Stockholm, Sweden
    Arch Suicide Res 13:297-301. 2009
    ..Homicide is a strong predictor of future suicide and similar biological mechanisms may be involved in violent criminality and suicidal behavior...
  19. doi request reprint Long-term suicide risk in schizophrenia spectrum psychoses: survival analysis by gender
    Andreas Carlborg
    Department of Clinical Neuroscience, Psychiatry, Karolinska University Hospital Solna, Stockholm, Sweden
    Arch Suicide Res 12:347-51. 2008
    ..These results indicate that patients with schizophrenia spectrum psychoses have a high long term suicide risk in both men and women. The high suicide risk in female patients deserves further research attention...
  20. ncbi request reprint The relationship between CSF HVA/5-HIAA ratio and suicide intent in suicide attempters
    Jussi Jokinen
    Department of Clinical Neuroscience, Psychiatry Section, Karolinska University Hospital Solna, Stockholm, Sweden
    Arch Suicide Res 11:187-92. 2007
    ....
  21. doi request reprint CSF kynurenic acid and suicide risk in schizophrenia spectrum psychosis
    Andreas Carlborg
    Department of Clinical Neuroscience, Psychiatry Section, Karolinska Institutet, Karolinska University Hospital Solna, SE 171 76 Stockholm, Sweden
    Psychiatry Res 205:165-7. 2013
    ..Three patients died from suicide and nine patients had a history of attempted suicide. Patients with attempted suicide had significantly lower concentrations of CSF KYNA...
  22. doi request reprint Thyroid hormones and adult interpersonal violence among women with borderline personality disorder
    Cave Sinai
    Department of Clinical Neuroscience Psychiatry, Karolinska Institutet, Karolinska University Hospital, Solna SE 171 76 Stockholm, Sweden Electronic address
    Psychiatry Res 227:253-7. 2015
    ..Association between T3 levels and violent/aggressive behavior earlier reported exclusively in male samples may be valid also in females with BPD. ..
  23. doi request reprint Low plasma vascular endothelial growth factor (VEGF) associated with completed suicide
    Josef Isung
    Department of Clinical Neuroscience, Karolinska Institute, Stockholm, Sweden
    World J Biol Psychiatry 13:468-73. 2012
    ..Several cytokines have been identified as potentially important in understanding the pathophysiology of mood disorders and suicidality. Here we aimed to identify new inflammatory biomarkers for suicide prediction...
  24. ncbi request reprint CSF 5-HIAA and the rorschach test in patients who have attempted suicide
    Eva Lundbäck
    Department of Clinical Neuroscience, Psychiatry Section, Karolinska Institutet, Stockholm, Sweden
    Arch Suicide Res 10:339-45. 2006
    ..These results raise questions whether shame may be involved in the psychobiology of suicide...
  25. doi request reprint CSF 5-HIAA, attempted suicide and suicide risk in schizophrenia spectrum psychosis
    Andreas Carlborg
    Department of Clinical Neuroscience, Psychiatry Section, Karolinska Institutet, Karolinska University Hospital, Solna, Sweden
    Schizophr Res 112:80-5. 2009
    ..The objective of this study was to investigate the relationship between levels of CSF 5-HIAA, CSF HVA and suicidal behavior in patients with schizophrenia spectrum psychosis...
  26. doi request reprint HPA axis dysregulation in men with hypersexual disorder
    Andreas Chatzittofis
    Department of Clinical Neuroscience Psychiatry, Karolinska Institutet, Karolinska University Hospital, Solna, SE 171 76 Stockholm, Sweden Electronic address
    Psychoneuroendocrinology 63:247-53. 2016
    ..The results suggest HPA axis dysregulation in male patients with hypersexual disorder...
  27. doi request reprint Family history of suicide and exposure to interpersonal violence in childhood predict suicide in male suicide attempters
    Mia Rajalin
    Department of Clinical Neuroscience Psychiatry, Karolinska Institutet, Karolinska University Hospital, Solna, SE 171 76 Stockholm, Sweden
    J Affect Disord 148:92-7. 2013
    ..The aim of the present study was to assess the impact of family history of suicide and childhood trauma on suicide risk and on severity of suicide attempt in suicide attempters...
  28. doi request reprint Suicide in schizophrenia
    Andreas Carlborg
    Karolinska University Hospital, Stockholm, Sweden
    Expert Rev Neurother 10:1153-64. 2010
    ..Management of suicide risk includes both medical treatment and psychosocial interventions. Still, risk factors are crude; efforts to predict individual suicides have not proved useful and more research is needed...
  29. doi request reprint Seasonality of suicide in Sweden: relationship with psychiatric disorder
    Johan Reutfors
    Clinical Epidemiology Unit, Department of Medicine, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden
    J Affect Disord 119:59-65. 2009
    ..The present study aims to assess suicide seasonality patterns with regard to the history of psychiatric morbidity among suicide victims...
  30. doi request reprint Thyroid hormones and personality traits in attempted suicide
    Cave Sinai
    Department of Clinical Neuroscience Psychiatry, Karolinska Institutet, Karolinska University Hospital, Solna, SE 17176 Stockholm, Sweden
    Psychoneuroendocrinology 34:1526-32. 2009
    ..These results indicate that HPT function may be related to Aggressiveness and Detachment in male suicide attempters...
  31. pmc Suicide Risk Associated with Experience of Violence and Impulsivity in Alcohol Dependent Patients
    Lotfi Khemiri
    Department of Clinical Neuroscience, Center for Psychiatry Research, Karolinska Institutet, Stockholm, Sweden
    Sci Rep 6:19373. 2016
    ..Future longitudinal studies assessing these traits are needed to evaluate their potential role in identifying AD patients at risk of future suicide. ..
  32. doi request reprint CSF and plasma testosterone in attempted suicide
    Jon Stefansson
    Department of Clinical Neuroscience Psychiatry, Karolinska Institutet, Stockholm, Sweden
    Psychoneuroendocrinology 74:1-6. 2016
    ..Higher CSF testosterone levels may be associated with attempted suicide in young men through association with both aggressiveness and impulsivity, a key endophenotype in young male suicide attempters...
  33. pmc Psychiatric and neurological disorders in late adolescence and risk of convictions for violent crime in men
    Tomas Moberg
    Department of Clinical Neuroscience Psychiatry, Karolinska Institutet, Stockholm, Sweden
    BMC Psychiatry 15:299. 2015
    ..In the present study, we analysed psychiatric and neurological disorders in relation to the risk of convictions for violent crime, taking into account early behavioural and socio-economic risk factors...
  34. pmc Shame-proneness in attempted suicide patients
    Maria Wiklander
    Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
    BMC Psychiatry 12:50. 2012
    ..We hypothesized that the attempted suicide patients would be more shame-prone than non-suicidal patients and healthy controls...
  35. doi request reprint Dialectical behavior therapy-based skills training for family members of suicide attempters
    Mia Rajalin
    Sodermalm Psychiatric Outpatient Services, Stockholm County Council and Department of Clinical Neuroscience Psychiatry, Karolinska Institutet, Stockholm, Sweden
    Arch Suicide Res 13:257-63. 2009
    ..These results provide support for the need and importance of a DBT-based skills training program addressed specifically to family members of suicide attempters...
  36. doi request reprint Prescribed psychiatric medication among multiple sclerosis patients before and after disability pension: a register study with matched controls
    Philip Brenner
    Department of Clinical Neuroscience, Karolinska Institutet, Center for Psychiatry Research, Karolinska Universitetssjukhuset R5 00, 171 77, Stockholm, Sweden
    Soc Psychiatry Psychiatr Epidemiol 51:1047-54. 2016
    ..The objective of this study was to investigate the association between prescriptions of psychiatric medication and time before and after receiving full-time DP in MS patients compared with matched controls...
  37. pmc Disability pension due to common mental disorders and subsequent suicidal behaviour: a population-based prospective cohort study
    Syed Ghulam Rahman
    Division of Insurance Medicine, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
    BMJ Open 6:e010152. 2016
    ..This study aimed to investigate associations of different measures (main and secondary diagnoses, duration and grade) of DP due to common mental disorders (CMD) with subsequent suicidal behaviour, considering gender and age differences...
  38. doi request reprint Plasma apolipoprotein E and severity of suicidal behaviour
    Peter Asellus
    Department of Clinical Neuroscience Psychiatry, Karolinska Institutet, R5, Karolinska University Hospital Solna, Stockholm SE 171 76, Sweden Electronic address
    J Affect Disord 190:137-42. 2016
    ..Our findings indicate that ApoE may be related to stress and trauma and the temporal severity of suicidal behaviour. ..
  39. pmc Risk factors for adult interpersonal violence in suicide attempters
    Tomas Moberg
    The Department of Clinical Neuroscience Psychiatry, Karolinska Institutet, Karolinska University Hospital, Solna, SE 171 76 Stockholm, Sweden
    BMC Psychiatry 14:195. 2014
    ....
  40. doi request reprint Long-term outcomes of pharmacologically treated versus non-treated adults with ADHD and substance use disorder: a naturalistic study
    Berit Bihlar Muld
    SiS Institution Hornö, Enkoping, Sweden Department of Women s and Children s Health, Paediatric Neuropsychiatry Unit, Center of Neurodevelopmental Disorders at Karolinska Institutet KIND, Karolinska Institutet, Stockholm, Sweden
    J Subst Abuse Treat 51:82-90. 2015
    ..Our aim was to investigate whether pharmacological treatment was associated with improved long-term psychosocial outcomes...
  41. doi request reprint Cholesterol and the "Cycle of Violence" in attempted suicide
    Peter Asellus
    Department of Clinical Neuroscience Psychiatry, Karolinska Institutet, Karolinska University Hospital, Solna, SE 171 76 Stockholm, Sweden
    Psychiatry Res 215:646-50. 2014
    ..25, p=0.2). Comorbid substance abuse predicted violent behaviour as an adult only in patients with serum cholesterol above median. Serum cholesterol may modify the effect of the "Cycle of Violence". ..
  42. pmc Interpersonal violence and the prediction of short-term risk of repeat suicide attempt
    Axel Haglund
    Department of Clinical Neuroscience, Centre for Psychiatry Research, Karolinska Institutet, Stockholm, Sweden
    Sci Rep 6:36892. 2016
    ....
  43. pmc Violent and non-violent methods of attempted and completed suicide in Swedish young men: the role of early risk factors
    Marlene Stenbacka
    Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
    BMC Psychiatry 15:196. 2015
    ..Adolescent risk factors for the choice of violent or non-violent methods for suicide attempts and the risk of subsequent suicide were studied using a longitudinal design...
  44. doi request reprint Cerebrospinal fluid kynurenines in multiple sclerosis; relation to disease course and neurocognitive symptoms
    Shahin Aeinehband
    Department of Clinical Neuroscience, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden Electronic address
    Brain Behav Immun 51:47-55. 2016
    ..In contrast, PPMS patients displayed a more divergent pattern more resembling inflammatory conditions such as systemic lupus erythematosus. The pattern of KP metabolites in RRMS patients could not predict neurocognitive symptoms. ..
  45. pmc Attention deficit/hyperactivity disorders with co-existing substance use disorder is characterized by early antisocial behaviour and poor cognitive skills
    Berit Bihlar Muld
    Department of Women s and Children s Health, Karolinska Institute, Pediatric Neuropsychiatry Unit, Center of Neurodevelopmental Disorders at Karolinska Institutet KIND, Stockholm, Gävlegatan 22B, SE 113 30, Sweden
    BMC Psychiatry 13:336. 2013
    ..This context enables a reliable clinical assessment of ADHD in individuals with severe substance use disorder (SUD)...
  46. pmc Association of suicide attempts with acne and treatment with isotretinoin: retrospective Swedish cohort study
    Anders Sundström
    Centre for Pharmacoepidemiology, Karolinska Institute, Karolinska University Hospital T2, 171 76 Stockholm, Sweden
    BMJ 341:c5812. 2010
    ..To assess the risk of attempted suicide before, during, and after treatment with isotretinoin for severe acne...