Affiliation: Karolinska Institutet
- Comparative genomic hybridization and karyotyping of human embryonic stem cells reveals the occurrence of an isodicentric X chromosome after long-term cultivationJ Inzunza
Department of Clinical Sciences, Division of Obstetrics and Gynaecology, Karolinska Institutet, Karolinska University Hospital, Huddinge, S 141 86 Stockholm, Sweden
Mol Hum Reprod 10:461-6. 2004..Single cell CGH is a method that can be used for continuous analysis of the hES cell lines during cultivation, in order to detect chromosome imbalance...
- Clinical outcome of treatment cycles using preimplantation genetic diagnosis for structural chromosomal abnormalitiesM Fridström
Department of Clinical Sciences, Division of Obstetrics and Gynecology, Karolinska Institute, K 57 Huddinge University Hospital, S 141 86 Stockholm, Sweden
Prenat Diagn 21:781-7. 2001..To explore oocyte recovery, embryo quality, the number of transferable embryos and pregnancy rate after preimplantation genetic diagnosis (PGD) in patients with structural chromosomal aberrations...
- Single cell CGH analysis reveals a high degree of mosaicism in human embryos from patients with balanced structural chromosome aberrationsH Malmgren
Department of Molecular Medicine, Karolinska Institutet, Karolinska Hospital, S 171 76 Stockholm, Sweden
Mol Hum Reprod 8:502-10. 2002..All of the embryos (100%) were mosaic, containing more than one chromosomally uniform cell line, or even chaotic with a different chromosomal content in each blastomere...