Erik Hedman

Summary

Affiliation: Karolinska Institutet
Country: Sweden

Publications

  1. doi request reprint Health anxiety in obsessive compulsive disorder and obsessive compulsive symptoms in severe health anxiety: An investigation of symptom profiles
    Erik Hedman
    Karolinska Institutet, Department of Clinical Neuroscience, Division of Psychology, Stockholm, Sweden Karolinska Institutet, Department of Clinical Neuroscience, Osher Center for Integrative Medicine, Stockholm, Sweden Electronic address
    J Anxiety Disord 45:80-86. 2017
  2. ncbi request reprint Exposure-based cognitive-behavioural therapy via the internet and as bibliotherapy for somatic symptom disorder and illness anxiety disorder: randomised controlled trial
    Erik Hedman
    Erik Hedman, PhD, Department of Clinical Neuroscience, Osher Center for Integrative Medicine and Division of Psychology, Karolinska Institutet, Stockholm, Sweden Erland Axelsson, MSc, Erik Andersson, PhD, Department of Clinical Neuroscience, Division of Psychology, Karolinska Institutet, Stockholm, Sweden Mats Lekander, PhD, Department of Clinical Neuroscience, Osher Center for Integrative Medicine, Karolinska Institutet, and Stress Research Institute, Stockholm University, Stockholm, Sweden Brjánn Ljósson, PhD, Department of Clinical Neuroscience, Division of Psychology, Karolinska Institutet, Stockholm, Sweden
    Br J Psychiatry 209:407-413. 2016
  3. doi request reprint Psychometric properties of Internet-administered measures of health anxiety: an investigation of the Health Anxiety Inventory, the Illness Attitude Scales, and the Whiteley Index
    Erik Hedman
    Karolinska Institutet, Department of Clinical Neuroscience, Division of Psychology, Stockholm, Sweden Karolinska Institutet, Department of Clinical Neuroscience, Osher Center for Integrative Medicine, Stockholm, Sweden Linköping University, Department of Behavioural Sciences and Learning, Linkoping, Sweden Electronic address
    J Anxiety Disord 31:32-7. 2015
  4. doi request reprint Predictors in Internet-delivered cognitive behavior therapy and behavioral stress management for severe health anxiety
    Erik Hedman
    Department of Clinical Neuroscience, Osher Center for Integrative Medicine, Karolinska Institutet, Stockholm, Sweden Department of Clinical Neuroscience, Division of Psychology, Karolinska Institutet, Stockholm, Sweden Electronic address
    Behav Res Ther 64:49-55. 2015
  5. doi request reprint Clinical effectiveness and cost-effectiveness of Internet- vs. group-based cognitive behavior therapy for social anxiety disorder: 4-year follow-up of a randomized trial
    Erik Hedman
    Department of Clinical Neuroscience, Osher Center for Integrative Medicine, Karolinska Institutet, Stockholm, Sweden Department of Clinical Neuroscience, Division of Psychology, Karolinska Institutet, Stockholm, Sweden Electronic address
    Behav Res Ther 59:20-9. 2014
  6. pmc Sudden gains in internet-based cognitive behaviour therapy for severe health anxiety
    Erik Hedman
    Department of Clinical Neuroscience, Division of Psychiatry, Karolinska Institutet, Stockholm, Sweden Department of Clinical Neuroscience, Osher Center for Integrative Medicine, Karolinska Institutet, Stockholm, Sweden Department of Clinical Neuroscience, Division of Psychology, Karolinska Institutet, Stockholm, Sweden Electronic address
    Behav Res Ther 54:22-9. 2014
  7. doi request reprint Effectiveness of Internet-based cognitive behaviour therapy for depression in routine psychiatric care
    Erik Hedman
    Department of Clinical Neuroscience, Division of Psychiatry, Karolinska Institutet, Sweden Department of Clinical Neuroscience, Osher Center for Integrative Medicine Karolinska Institutet, Stockholm, Sweden Department of Clinical Neuroscience, Division of Psychology, Karolinska Institutet, Stockholm, Sweden Electronic address
    J Affect Disord 155:49-58. 2014
  8. pmc Telephone versus internet administration of self-report measures of social anxiety, depressive symptoms, and insomnia: psychometric evaluation of a method to reduce the impact of missing data
    Erik Hedman
    Osher Center for Integrative Medicine, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
    J Med Internet Res 15:e229. 2013
  9. doi request reprint Predictors of outcome in Internet-based cognitive behavior therapy for severe health anxiety
    Erik Hedman
    Department of Clinical Neuroscience, Division of Psychiatry, Karolinska Institutet, Retzius vag 8, SE 171 77 Stockholm, Sweden Department of Clinical Neuroscience, Osher Center for Integrative Medicine, Karolinska Institutet, Stockholm, Sweden Department of Clinical Neuroscience, Division of Psychology, Karolinska Institutet, Stockholm, Sweden Electronic address
    Behav Res Ther 51:711-7. 2013
  10. doi request reprint Mediators in psychological treatment of social anxiety disorder: individual cognitive therapy compared to cognitive behavioral group therapy
    Erik Hedman
    Department of Clinical Neuroscience, Osher Center for Integrative Medicine, Karolinska Institutet, Stockholm, Sweden Department of Clinical Neuroscience, Division of Psychology, Karolinska Institutet, Stockholm, Sweden Electronic address
    Behav Res Ther 51:696-705. 2013

Detail Information

Publications50

  1. doi request reprint Health anxiety in obsessive compulsive disorder and obsessive compulsive symptoms in severe health anxiety: An investigation of symptom profiles
    Erik Hedman
    Karolinska Institutet, Department of Clinical Neuroscience, Division of Psychology, Stockholm, Sweden Karolinska Institutet, Department of Clinical Neuroscience, Osher Center for Integrative Medicine, Stockholm, Sweden Electronic address
    J Anxiety Disord 45:80-86. 2017
    ..Among participants with comorbid OCD, effect sizes were large on measures of health anxiety and moderate to large on OCD measures. We conclude that SHA and OCD are separate psychiatric disorders with limited overlap in symptom profiles...
  2. ncbi request reprint Exposure-based cognitive-behavioural therapy via the internet and as bibliotherapy for somatic symptom disorder and illness anxiety disorder: randomised controlled trial
    Erik Hedman
    Erik Hedman, PhD, Department of Clinical Neuroscience, Osher Center for Integrative Medicine and Division of Psychology, Karolinska Institutet, Stockholm, Sweden Erland Axelsson, MSc, Erik Andersson, PhD, Department of Clinical Neuroscience, Division of Psychology, Karolinska Institutet, Stockholm, Sweden Mats Lekander, PhD, Department of Clinical Neuroscience, Osher Center for Integrative Medicine, Karolinska Institutet, and Stress Research Institute, Stockholm University, Stockholm, Sweden Brjánn Ljósson, PhD, Department of Clinical Neuroscience, Division of Psychology, Karolinska Institutet, Stockholm, Sweden
    Br J Psychiatry 209:407-413. 2016
    ..There are no previous treatment studies for these disorders. Cognitive-behavioural therapy (CBT) delivered as therapist-guided or unguided internet treatment or as unguided bibliotherapy could be used to increase treatment accessibility...
  3. doi request reprint Psychometric properties of Internet-administered measures of health anxiety: an investigation of the Health Anxiety Inventory, the Illness Attitude Scales, and the Whiteley Index
    Erik Hedman
    Karolinska Institutet, Department of Clinical Neuroscience, Division of Psychology, Stockholm, Sweden Karolinska Institutet, Department of Clinical Neuroscience, Osher Center for Integrative Medicine, Stockholm, Sweden Linköping University, Department of Behavioural Sciences and Learning, Linkoping, Sweden Electronic address
    J Anxiety Disord 31:32-7. 2015
    ....
  4. doi request reprint Predictors in Internet-delivered cognitive behavior therapy and behavioral stress management for severe health anxiety
    Erik Hedman
    Department of Clinical Neuroscience, Osher Center for Integrative Medicine, Karolinska Institutet, Stockholm, Sweden Department of Clinical Neuroscience, Division of Psychology, Karolinska Institutet, Stockholm, Sweden Electronic address
    Behav Res Ther 64:49-55. 2015
    ..The findings of the present study can be of high clinical value as they provide information about factors of importance for outcome in the treatment of severe health anxiety...
  5. doi request reprint Clinical effectiveness and cost-effectiveness of Internet- vs. group-based cognitive behavior therapy for social anxiety disorder: 4-year follow-up of a randomized trial
    Erik Hedman
    Department of Clinical Neuroscience, Osher Center for Integrative Medicine, Karolinska Institutet, Stockholm, Sweden Department of Clinical Neuroscience, Division of Psychology, Karolinska Institutet, Stockholm, Sweden Electronic address
    Behav Res Ther 59:20-9. 2014
    ..We conclude that ICBT for SAD yields large sustainable effects and is at least as long-term effective as CBGT. Intervention costs of both treatments are offset by net societal cost reductions in a short time. ..
  6. pmc Sudden gains in internet-based cognitive behaviour therapy for severe health anxiety
    Erik Hedman
    Department of Clinical Neuroscience, Division of Psychiatry, Karolinska Institutet, Stockholm, Sweden Department of Clinical Neuroscience, Osher Center for Integrative Medicine, Karolinska Institutet, Stockholm, Sweden Department of Clinical Neuroscience, Division of Psychology, Karolinska Institutet, Stockholm, Sweden Electronic address
    Behav Res Ther 54:22-9. 2014
    ..The aim of this study was to investigate the role of sudden gains in internet-based cognitive behavioural therapy for severe health anxiety...
  7. doi request reprint Effectiveness of Internet-based cognitive behaviour therapy for depression in routine psychiatric care
    Erik Hedman
    Department of Clinical Neuroscience, Division of Psychiatry, Karolinska Institutet, Sweden Department of Clinical Neuroscience, Osher Center for Integrative Medicine Karolinska Institutet, Stockholm, Sweden Department of Clinical Neuroscience, Division of Psychology, Karolinska Institutet, Stockholm, Sweden Electronic address
    J Affect Disord 155:49-58. 2014
    ..Knowledge on the effectiveness of the treatment, i.e. how it works when delivered within routine care, is however scarce. The aim of this study was to investigate the effectiveness of ICBT for depression...
  8. pmc Telephone versus internet administration of self-report measures of social anxiety, depressive symptoms, and insomnia: psychometric evaluation of a method to reduce the impact of missing data
    Erik Hedman
    Osher Center for Integrative Medicine, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
    J Med Internet Res 15:e229. 2013
    ..One way of reducing the negative impact of missing data could be to use telephone administration of self-report measures as a means to complete the data missing from the online data collection...
  9. doi request reprint Predictors of outcome in Internet-based cognitive behavior therapy for severe health anxiety
    Erik Hedman
    Department of Clinical Neuroscience, Division of Psychiatry, Karolinska Institutet, Retzius vag 8, SE 171 77 Stockholm, Sweden Department of Clinical Neuroscience, Osher Center for Integrative Medicine, Karolinska Institutet, Stockholm, Sweden Department of Clinical Neuroscience, Division of Psychology, Karolinska Institutet, Stockholm, Sweden Electronic address
    Behav Res Ther 51:711-7. 2013
    ..We conclude that baseline symptom burden and adherence to treatment have strong predictive effects in Internet-based CBT for severe health anxiety...
  10. doi request reprint Mediators in psychological treatment of social anxiety disorder: individual cognitive therapy compared to cognitive behavioral group therapy
    Erik Hedman
    Department of Clinical Neuroscience, Osher Center for Integrative Medicine, Karolinska Institutet, Stockholm, Sweden Department of Clinical Neuroscience, Division of Psychology, Karolinska Institutet, Stockholm, Sweden Electronic address
    Behav Res Ther 51:696-705. 2013
    ..These results support the importance of the putative mediators, but suggest that their relative weights are moderated by treatment type...
  11. pmc Shame and guilt in social anxiety disorder: effects of cognitive behavior therapy and association with social anxiety and depressive symptoms
    Erik Hedman
    Department of Clinical Neuroscience, Osher Center for Integrative Medicine, Karolinska Institutet, Stockholm, Sweden
    PLoS ONE 8:e61713. 2013
    ..We conclude that shame and social anxiety are associated and that it is likely that persons with SAD are more prone to experience shame than persons without SAD. Also, CBT is associated with shame reduction in the treatment of SAD...
  12. doi request reprint Cost-effectiveness and long-term effectiveness of internet-based cognitive behaviour therapy for severe health anxiety
    E Hedman
    Division of Psychology, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
    Psychol Med 43:363-74. 2013
    ..The aim of this study was to investigate the cost-effectiveness and 1-year treatment effects of ICBT for severe health anxiety...
  13. doi request reprint Cognitive behavior therapy via the Internet: a systematic review of applications, clinical efficacy and cost-effectiveness
    Erik Hedman
    Department of Clinical Neuroscience, Osher Center for Integrative Medicine, Karolinska Institutet, Stockholm, Sweden
    Expert Rev Pharmacoecon Outcomes Res 12:745-64. 2012
    ..The large effects and the limited therapist time required suggest that the treatment is highly cost effective for well-established indications...
  14. pmc Internet-based cognitive behavior therapy for obsessive compulsive disorder: a pilot study
    Erik Andersson
    Department of Clinical Neuroscience, Division of Psychiatry, Karolinska Institutet, Stockholm, Sweden
    BMC Psychiatry 11:125. 2011
    ..Internet-based CBT (ICBT) with therapist support is a way to increase access to CBT but has not been developed or tested for OCD. The aim of this study was to evaluate ICBT for OCD...
  15. doi request reprint Long-term follow-up of internet-delivered exposure and mindfulness based treatment for irritable bowel syndrome
    Brjann Ljotsson
    Center for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
    Behav Res Ther 49:58-61. 2011
    ..This study suggests that internet-delivered CBT based on exposure and mindfulness has long-term beneficial effects for IBS-patients...
  16. pmc Acceptability, effectiveness, and cost-effectiveness of internet-based exposure treatment for irritable bowel syndrome in a clinical sample: a randomized controlled trial
    Brjann Ljotsson
    Department of Clinical Neuroscience, Division of Psychiatry, Karolinska Institutet, Stockholm, Sweden
    BMC Gastroenterol 11:110. 2011
    ..We aimed to investigate the acceptability, effectiveness, and cost-effectiveness of ICBT for IBS using a consecutively recruited sample from a gastroenterological clinic...
  17. doi request reprint Internet-delivered exposure-based treatment vs. stress management for irritable bowel syndrome: a randomized trial
    Brjann Ljotsson
    Department of Clinical Neuroscience, Division of Psychiatry, Karolinska Institutet, Stockholm, Sweden
    Am J Gastroenterol 106:1481-91. 2011
    ..We compared ICBT with internet-delivered stress management (ISM) for IBS to assess whether the effects of ICBT are specific...
  18. doi request reprint Cost-effectiveness of Internet-based cognitive behavior therapy vs. cognitive behavioral group therapy for social anxiety disorder: results from a randomized controlled trial
    Erik Hedman
    Department of Clinical Neuroscience, Division of Psychiatry, Karolinska Institutet, Stockholm, Sweden
    Behav Res Ther 49:729-36. 2011
    ..We conclude that ICBT can be more cost-effective than CBGT in the treatment of SAD and that both treatments reduce societal costs for SAD...
  19. doi request reprint Effectiveness and cost offset analysis of group CBT for hypochondriasis delivered in a psychiatric setting: an open trial
    Erik Hedman
    Department of Clinical Neuroscience, Division of Psychiatry, Karolinska Institutet, Stockholm, Sweden
    Cogn Behav Ther 39:239-50. 2010
    ..03-1.72). Medical and nonmedical costs were substantially lowered. The authors conclude that group-based CBT delivered in a psychiatric setting is an effective and potentially highly cost-effective treatment for hypochondriasis...
  20. doi request reprint Internet-based cognitive-behavioural therapy for severe health anxiety: randomised controlled trial
    Erik Hedman
    Karolinska Institutet, Department of Clinical Neuroscience, Stockholm, Sweden
    Br J Psychiatry 198:230-6. 2011
    ..Internet-based CBT, including guidance in the form of minimal therapist contact via email, could be a more accessible treatment, but no study has investigated internet-based CBT for hypochondriasis...
  21. pmc Cost effectiveness of internet-based cognitive behaviour therapy and behavioural stress management for severe health anxiety
    Erik Hedman
    Department of Clinical Neuroscience, Division of Psychology, Karolinska Institutet, Stockholm, Sweden Department of Clinical Neuroscience, Osher Center for Integrative Medicine, Karolinska Institutet, Stockholm, Sweden
    BMJ Open 6:e009327. 2016
    ..ICBT was hypothesised to be the more cost-effective treatment...
  22. pmc Genetic polymorphisms in monoamine systems and outcome of cognitive behavior therapy for social anxiety disorder
    Evelyn Andersson
    Department of Clinical Neuroscience, Division of Psychiatry, Karolinska Institutet, Stockholm, Sweden
    PLoS ONE 8:e79015. 2013
    ..The aim of the present study was to investigate if these three gene variants predicted response to CBT in a large sample of SAD patients...
  23. pmc Mediators in internet-based cognitive behavior therapy for severe health anxiety
    Erik Hedman
    Department of Clinical Neuroscience, Division of Psychiatry, Karolinska Institutet, Stockholm, Sweden Department of Clinical Neuroscience, Osher Center for Integrative Medicine, Karolinska Institutet, Stockholm, Sweden Department of Clinical Neuroscience, Division of Psychology, Karolinska Institutet, Stockholm, Sweden
    PLoS ONE 8:e77752. 2013
    ..The findings have theoretical and clinical implications as they indicate processes that may be causally related to the improvements observed after CBT for health anxiety. ..
  24. pmc A 5-Year follow-up of internet-based cognitive behavior therapy for social anxiety disorder
    Erik Hedman
    Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
    J Med Internet Res 13:e39. 2011
    ..Several trials have demonstrated that Internet-based CBT can be effective for SAD in the shorter term. However, the long-term effects of Internet-based CBT for SAD are less well known...
  25. doi request reprint Testing the Mediating Effects of Obsessive Beliefs in Internet-Based Cognitive Behaviour Therapy for Obsessive-Compulsive Disorder: Results from a Randomized Controlled Trial
    Erik Andersson
    Department of Clinical Neuroscience, Division of Psychiatry, Karolinska Institutet, Stockholm, Sweden
    Clin Psychol Psychother 22:722-32. 2015
    ..We conclude that, although obsessive beliefs were significantly reduced at post-treatment for the ICBT group, early increase rather than decrease in obsessive beliefs predicted favourable outcome...
  26. pmc Predictors and moderators of internet- and group-based cognitive behaviour therapy for panic disorder
    Samir El Alaoui
    Karolinska Institutet, Department of Clinical Neuroscience, Division of Psychiatry, Stockholm, Sweden
    PLoS ONE 8:e79024. 2013
    ..These results suggest that both ICBT and GCBT are effective treatment modalities for PD and that it is possible to predict a significant proportion of the long-term outcome variance based on clinical variables. ..
  27. doi request reprint Mechanisms of change in an exposure-based treatment for irritable bowel syndrome
    Brjann Ljotsson
    Department of Clinical Neuroscience, Division of Psychology, Karolinska Institutet
    J Consult Clin Psychol 81:1113-26. 2013
    ..The original study found that ICBT was more effective than ISM in improving IBS symptoms...
  28. pmc Internet-based cognitive behavior therapy vs. cognitive behavioral group therapy for social anxiety disorder: a randomized controlled non-inferiority trial
    Erik Hedman
    Department of Clinical Neuroscience, Division of Psychiatry, Karolinska Institutet, Stockholm, Sweden
    PLoS ONE 6:e18001. 2011
    ..Our aim was to investigate if ICBT is at least as effective as CBGT for SAD when treatments are delivered in a psychiatric setting...
  29. pmc Cost-effectiveness of internet-based cognitive behavior therapy for irritable bowel syndrome: results from a randomized controlled trial
    Erik Andersson
    Department of Clinical Neuroscience, Stockholm Center for Psychiatry Research, Karolinska Institutet, Stockholm, Sweden
    BMC Public Health 11:215. 2011
    ..The aim of this study was to evaluate the cost-effectiveness of a new treatment alternative, internet-delivered CBT based on exposure and mindfulness exercises...
  30. pmc The Brunnsviken Brief Quality of Life Scale (BBQ): Development and Psychometric Evaluation
    Philip Lindner
    a Department of Psychology, Stockholm University, Stockholm, Sweden
    Cogn Behav Ther 45:182-95. 2016
    ..We conclude that the BBQ is a valid and reliable measure of subjective QoL for use in clinical and research settings. The BBQ is presently available in 31 languages and can be freely downloaded from www.bbqscale.com . ..
  31. pmc Predictors of Symptomatic Change and Adherence in Internet-Based Cognitive Behaviour Therapy for Social Anxiety Disorder in Routine Psychiatric Care
    Samir El Alaoui
    Department of Clinical Neuroscience, Division of Psychiatry, Karolinska Institutet, Stockholm, Sweden
    PLoS ONE 10:e0124258. 2015
    ..Consequently, the aim of this study was to identify individual characteristics and treatment program related factors that could help clinicians predict treatment outcomes and adherence for individuals with SAD...
  32. doi request reprint Exposure and mindfulness based therapy for irritable bowel syndrome--an open pilot study
    Brjann Ljotsson
    Center for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
    J Behav Ther Exp Psychiatry 41:185-90. 2010
    ..Treatment gains were maintained at follow-up. The results support the use of exposure and mindfulness based strategies in the treatment of IBS, but further randomised studies are needed to confirm the efficacy of the treatment...
  33. pmc Optimal cut-off points on the health anxiety inventory, illness attitude scales and whiteley index to identify severe health anxiety
    Erik Hedman
    Karolinska Institutet, Department of Clinical Neuroscience, Division of Psychology, Stockholm, Sweden Karolinska Institutet, Department of Clinical Neuroscience, Osher Center for Integrative Medicine, Stockholm, Sweden
    PLoS ONE 10:e0123412. 2015
    ..The aim of this study was therefore to investigate the HAI, IAS and WI as proximal diagnostic instruments for severe health anxiety defined as DSM-IV hypochondriasis...
  34. pmc Personality change following internet-based cognitive behavior therapy for severe health anxiety
    Erik Hedman
    Department of Clinical Neuroscience, Division of Psychiatry, Karolinska Institutet, Stockholm, Sweden Department of Clinical Neuroscience, Osher Center for Integrative Medicine, Karolinska Institutet, Stockholm, Sweden Department of Clinical Neuroscience, Division of Psychology, Karolinska Institutet, Stockholm, Sweden
    PLoS ONE 9:e113871. 2014
    ..The treatment thus has a broader impact than just reducing health anxiety...
  35. doi request reprint Internet-delivered cognitive behavior therapy for children and adolescents: A systematic review and meta-analysis
    Sarah Vigerland
    Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden Stockholm Health Care Services, Stockholm County Council, Sweden Electronic address
    Clin Psychol Rev 50:1-10. 2016
    ..62, 95% CI [0.41, 0.84]. The results suggest that CBT for psychiatric and somatic conditions in children and adolescents can be successfully adapted to an internet-delivered format...
  36. pmc Predicting Outcome in Internet-Based Cognitive Behaviour Therapy for Major Depression: A Large Cohort Study of Adult Patients in Routine Psychiatric Care
    Samir El Alaoui
    Department of Clinical Neuroscience, Centre for Psychiatric Research, Karolinska Institutet, Stockholm, Sweden
    PLoS ONE 11:e0161191. 2016
    ..Identification of such factors is important for clinicians when making treatment recommendations...
  37. doi request reprint Internet-delivered exposure-based cognitive-behavioural therapy and behavioural stress management for severe health anxiety: randomised controlled trial
    Erik Hedman
    Erik Hedman, PhD, Department of Clinical Neuroscience, Osher Center for Integrative Medicine, and Department of Clinical Neuroscience, Division of Psychology, Karolinska Institutet, Stockholm Erland Axelsson, MSc, Anders Görling, MSc, Carina Ritzman, MSc, Markus Ronnheden, MSc, Department of Clinical Neuroscience, Division of Psychology, Karolinska Institutet, Stockholm Samir El Alaoui, MSc, Erik Andersson, MSc, Department of Clinical Neuroscience, Division of Psychiatry, Karolinska Institutet, Stockholm Mats Lekander, PhD, Department of Clinical Neuroscience, Osher Center for Integrative Medicine, Karolinska Institutet, Stockholm, and Stress Research Institute, Stockholm University, Stockholm Brjánn Ljótsson, PhD, Department of Clinical Neuroscience, Division of Psychology, Karolinska Institutet, Stockholm, Sweden
    Br J Psychiatry 205:307-14. 2014
    ....
  38. pmc Using early change to predict outcome in cognitive behaviour therapy: exploring timeframe, calculation method, and differences of disorder-specific versus general measures
    Peter Schibbye
    Department of Clinical Neuroscience, Division of Psychiatry, Karolinska Institutet, Stockholm, Sweden Section of Psychiatry, Sundsvall Härnösand County Hospital, Vasternorrland County Council, Sweden
    PLoS ONE 9:e100614. 2014
    ..We conclude that a simple calculation method with a disorder-specific measure at week four seems to provide a good choice for predicting outcome in time-limited cognitive behavior therapy. ..
  39. doi request reprint Provoking symptoms to relieve symptoms: a randomized controlled dismantling study of exposure therapy in irritable bowel syndrome
    Brjann Ljotsson
    Department of Clinical Neuroscience, Division of Psychology, Karolinska Institutet, Nobels väg 9, 171 65 Stockholm, Sweden Electronic address
    Behav Res Ther 55:27-39. 2014
    ..This study provides evidence for the utility of exposure exercises in psychological treatments for IBS. ..
  40. doi request reprint D-Cycloserine vs Placebo as Adjunct to Cognitive Behavioral Therapy for Obsessive-Compulsive Disorder and Interaction With Antidepressants: A Randomized Clinical Trial
    Erik Andersson
    Division of Psychology, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden2Division of Psychiatry, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
    JAMA Psychiatry 72:659-67. 2015
    ..It is unclear whether d-cycloserine (DCS), a partial N-methyl-d-aspartate agonist that enhances fear extinction, can augment the effects of exposure-based cognitive behavioral therapy (CBT) for obsessive-compulsive disorder (OCD)...
  41. pmc Prediction of symptomatic improvement after exposure-based treatment for irritable bowel syndrome
    Brjann Ljotsson
    Department of Clinical Neuroscience, Division of Psychology, Karolinska Institutet, Nobels väg 9, Stockholm 171 65, Sweden
    BMC Gastroenterol 13:160. 2013
    ..The aim of the present study was to investigate several possible predictors of short- and long-term treatment outcome in terms of symptom improvement, based on data collected in the previously conducted treatment trial...
  42. doi request reprint Internet-delivered exposure and mindfulness based therapy for irritable bowel syndrome--a randomized controlled trial
    Brjann Ljotsson
    Center for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, University Hospital Huddinge, Stockholm, Sweden
    Behav Res Ther 48:531-9. 2010
    ..21). We conclude that CBT-based on exposure and mindfulness delivered via the Internet can be effective in treating IBS-patients, alleviating the total burden of symptoms and increasing quality of life...
  43. doi request reprint The health preoccupation diagnostic interview: inter-rater reliability of a structured interview for diagnostic assessment of DSM-5 somatic symptom disorder and illness anxiety disorder
    Erland Axelsson
    a Division of Psychology, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
    Cogn Behav Ther 45:259-69. 2016
    ..85. Disagreements primarily concerned (a) the severity of somatic symptoms, (b) the differential diagnosis of panic disorder, and (c) SSD specifiers. We conclude that the HPDI can be used to reliably diagnose DSM-5 SSD and IAD. ..
  44. ncbi request reprint Health anxiety in a disease-avoidance framework: Investigation of anxiety, disgust and disease perception in response to sickness cues
    Erik Hedman
    Department of Clinical Neuroscience, Osher Center for Integrative Medicine, Karolinska Institutet
    J Abnorm Psychol 125:868-878. 2016
    ..We suggest that disgust and cognitive biases relating to the disease-avoidance model are significant features of severe health anxiety. (PsycINFO Database Record..
  45. pmc Long-term effectiveness and outcome predictors of therapist-guided internet-based cognitive-behavioural therapy for social anxiety disorder in routine psychiatric care
    Samir El Alaoui
    Division of Psychiatry, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
    BMJ Open 5:e007902. 2015
    ..Further, there is some debate whether delivering psychological treatment via the internet may be suitable for more severely ill patients...
  46. pmc Effects of baseline problematic alcohol and drug use on internet-based cognitive behavioral therapy outcomes for depression, panic disorder and social anxiety disorder
    Mikael Gajecki
    Center for Psychiatric Research, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
    PLoS ONE 9:e104615. 2014
    ..Patients' problematic substance use prevalence and effects were explored in relation to internet-based cognitive behavioral therapy (ICBT) outcomes for depression, panic disorder and social anxiety disorder...
  47. doi request reprint Effectiveness and cost-effectiveness of individually tailored Internet-delivered cognitive behavior therapy for anxiety disorders in a primary care population: a randomized controlled trial
    Lise Bergman Nordgren
    Department of Behavioural Sciences and Learning, Linkoping University, SE 581 83 Linkoping, Sweden Electronic address
    Behav Res Ther 59:1-11. 2014
    ..Individually tailored ICBT is an effective and cost-effective treatment for primary-care patients with anxiety disorders with or without comorbidities...
  48. doi request reprint Internet-delivered acceptance and values-based exposure treatment for fibromyalgia: a pilot study
    Brjann Ljotsson
    a Department of Clinical Neuroscience, Division of Psychology, Karolinska Institutet, Stockholm, Sweden
    Cogn Behav Ther 43:93-104. 2014
    ..This study evaluated the efficacy, acceptability, and the health economic effects of an Internet-delivered acceptance and values-based exposure treatment for FM...
  49. pmc Development and Validation of a Brief Version of the Difficulties in Emotion Regulation Scale: The DERS-16
    Johan Bjureberg
    Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
    J Psychopathol Behav Assess 38:284-296. 2016
    ..In conclusion, the DERS-16 offers a valid and brief method for the assessment of overall emotion regulation difficulties...
  50. pmc Exposure-Based Cognitive Behavior Therapy for Children with Abdominal Pain: A Pilot Trial
    Maria Lalouni
    Department of Medicine Solna, Clinical Epidemiology Unit, Karolinska Institutet, Stockholm, Sweden
    PLoS ONE 11:e0164647. 2016
    ..Exposure-based cognitive behavior therapy (CBT) has shown large treatment effects in adults with irritable bowel syndrome, but has not been tested for children 8-12 years with P-FGIDs...