M Bradley

Summary

Affiliation: Karolinska Institutet
Country: Sweden

Publications

  1. ncbi Characterization by phenotype of families with atopic dermatitis
    M Bradley
    Department of Dermatology and Venereology, Karolinska Hospital, Karolinska Institutet, Stockholm, Sweden
    Acta Derm Venereol 80:106-10. 2000
  2. ncbi The Wiskott-Aldrich syndrome gene as a candidate gene for atopic dermatitis
    M Bradley
    Department of Dermatology and Venereology, Karolinska Institutet, Karolinska Hospital, Stockholm, Sweden
    Acta Derm Venereol 81:340-2. 2001
  3. ncbi Linkage and association to candidate regions in Swedish atopic dermatitis families
    C Söderhäll
    Department of Molecular Medicine, CMM 02, Karolinska Institutet, SE 171 76 Stockholm, Sweden
    Hum Genet 109:129-35. 2001
  4. ncbi Susceptibility loci for atopic dermatitis on chromosome 21 in a Swedish population
    L M Bu
    Department of Molecular Medicine, Karolinska Institutet at Karolinska Hospital, Stockholm, Sweden
    Allergy 61:617-21. 2006
  5. doi Lack of association between filaggrin gene mutations and onset of psoriasis in childhood
    M C G Winge
    Dermatology Unit, Department of Medicine Solna and Center for Molecular Medicine, Karolinska Institutet, Karolinska University Hospital Solna, Stockholm, Sweden
    J Eur Acad Dermatol Venereol 27:e124-7. 2013
  6. doi Cornulin, a marker of late epidermal differentiation, is down-regulated in eczema
    A Lieden
    Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden
    Allergy 64:304-11. 2009
  7. ncbi Genome-wide linkage analysis of allergic rhinoconjunctivitis in a Swedish population
    L M Bu
    Department of Molecular Medicine and Surgery, Stockholm Karolinska Institutet, Stockholm, Sweden
    Clin Exp Allergy 36:204-10. 2006
  8. ncbi Analysis of association and linkage for the interleukin-4 and interleukin-4 receptor b;alpha; regions in Swedish atopic dermatitis families
    C Söderhäll
    Departments of Molecular Medicine, Karolinska Institute at Karolinska Hospital, Stockholm, Sweden
    Clin Exp Allergy 32:1199-202. 2002
  9. doi Novel filaggrin mutation but no other loss-of-function variants found in Ethiopian patients with atopic dermatitis
    M C G Winge
    Dermatology Unit, Department of Medicine Solna, Karolinska Institutet, Karolinska University Hospital Solna, SE 171 76 Stockholm, Sweden
    Br J Dermatol 165:1074-80. 2011
  10. doi The tight junction gene Claudin-1 is associated with atopic dermatitis among Ethiopians
    S Asad
    Department of Molecular Medicine and Surgery and the Center for Molecular Medicine, Karolinska Institutet, Karolinska University Hospital Solna, Stockholm, Sweden
    J Eur Acad Dermatol Venereol 30:1939-1941. 2016

Collaborators

  • I C Kuo
  • S J Meggitt
  • M Wickman
  • C F Wahlgren
  • M Nordenskjold
  • M C G Winge
  • I Kockum
  • A Lieden
  • C Söderhäll
  • L M Bu
  • S Asad
  • E Ekelund
  • K D Bilcha
  • M Stahle
  • F Taylan
  • H Luthman
  • J Lysell
  • J Suneson
  • P Nikamo
  • D Shibeshi
  • A Sandilands
  • W H I McLean
  • C H Huang
  • L Mallbris
  • B Bjorksten
  • M D'Amato
  • L K Seng
  • M Nordensköld
  • C N A Palmer
  • K Y Chua
  • S P Lee
  • G Y Chin
  • G Pershagen
  • J Link
  • J Barker
  • J Kere
  • M Tengvall-Linder
  • A Saaf
  • E Melen
  • N J Reynolds

Detail Information

Publications11

  1. ncbi Characterization by phenotype of families with atopic dermatitis
    M Bradley
    Department of Dermatology and Venereology, Karolinska Hospital, Karolinska Institutet, Stockholm, Sweden
    Acta Derm Venereol 80:106-10. 2000
    ..Although the families were selected for genetic sib-pair linkage analysis, we believe that this material is representative of atopic dermatitis families managed at hospitals in Stockholm...
  2. ncbi The Wiskott-Aldrich syndrome gene as a candidate gene for atopic dermatitis
    M Bradley
    Department of Dermatology and Venereology, Karolinska Institutet, Karolinska Hospital, Stockholm, Sweden
    Acta Derm Venereol 81:340-2. 2001
    ..Our results indicate that either the WAS gene or another gene in the area contributes to the severity of atopic dermatitis...
  3. ncbi Linkage and association to candidate regions in Swedish atopic dermatitis families
    C Söderhäll
    Department of Molecular Medicine, CMM 02, Karolinska Institutet, SE 171 76 Stockholm, Sweden
    Hum Genet 109:129-35. 2001
    ..009). When a quantitative variable for the severity of atopic dermatitis was studied, evidence was found in favour of linkage to the 5q31-33 region, with the highest Z-score (2.06) close to the marker D5S458 (P<0.005)...
  4. ncbi Susceptibility loci for atopic dermatitis on chromosome 21 in a Swedish population
    L M Bu
    Department of Molecular Medicine, Karolinska Institutet at Karolinska Hospital, Stockholm, Sweden
    Allergy 61:617-21. 2006
    ..We have previously found several loci showing suggestive linkage on chromosomes 3q14, 13q14, 15q14-15 and 17q21, and weaker linkage to chromosomes 1p32, 4q24-26 and 21q21 in 109 Swedish families...
  5. doi Lack of association between filaggrin gene mutations and onset of psoriasis in childhood
    M C G Winge
    Dermatology Unit, Department of Medicine Solna and Center for Molecular Medicine, Karolinska Institutet, Karolinska University Hospital Solna, Stockholm, Sweden
    J Eur Acad Dermatol Venereol 27:e124-7. 2013
    ..Psoriasis is a highly heterogeneous disease and so far genetic studies have not taken the distinct sub-phenotype childhood onset into account...
  6. doi Cornulin, a marker of late epidermal differentiation, is down-regulated in eczema
    A Lieden
    Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden
    Allergy 64:304-11. 2009
    ..We then investigated CRNN as an eczema candidate gene and studied its polymorphism and the expression in the skin of eczema patients...
  7. ncbi Genome-wide linkage analysis of allergic rhinoconjunctivitis in a Swedish population
    L M Bu
    Department of Molecular Medicine and Surgery, Stockholm Karolinska Institutet, Stockholm, Sweden
    Clin Exp Allergy 36:204-10. 2006
    ..Like other atopic disorders such as allergic asthma and atopic dermatitis, the development involves complex interactions of genes and environmental factors...
  8. ncbi Analysis of association and linkage for the interleukin-4 and interleukin-4 receptor b;alpha; regions in Swedish atopic dermatitis families
    C Söderhäll
    Departments of Molecular Medicine, Karolinska Institute at Karolinska Hospital, Stockholm, Sweden
    Clin Exp Allergy 32:1199-202. 2002
    ..Several lines of evidence suggest that the IL-4 gene and the IL-4-receptor alpha (IL-4Ralpha) gene are involved in the development of atopic diseases...
  9. doi Novel filaggrin mutation but no other loss-of-function variants found in Ethiopian patients with atopic dermatitis
    M C G Winge
    Dermatology Unit, Department of Medicine Solna, Karolinska Institutet, Karolinska University Hospital Solna, SE 171 76 Stockholm, Sweden
    Br J Dermatol 165:1074-80. 2011
    ..However, it is unknown whether FLG mutations in the African population are a causative genetic factor for IV and predispose to AD, or whether other mechanisms are more prominent...
  10. doi The tight junction gene Claudin-1 is associated with atopic dermatitis among Ethiopians
    S Asad
    Department of Molecular Medicine and Surgery and the Center for Molecular Medicine, Karolinska Institutet, Karolinska University Hospital Solna, Stockholm, Sweden
    J Eur Acad Dermatol Venereol 30:1939-1941. 2016
    ..Although the filaggrin (FLG) gene is the major AD risk gene in European and Asian populations, disease-associated variants remain elusive in African populations...
  11. pmc Elevated expression and genetic association links the SOCS3 gene to atopic dermatitis
    E Ekelund
    Department of Molecular Medicine and Surgery, Department of Medicine, Karolinska University Hospital, Stockholm, SE 171 76, Sweden
    Am J Hum Genet 78:1060-5. 2006
    ..02 and P<.03). These results strongly suggest that SOCS3, located in a chromosomal region previously linked to the disease (17q25), is a susceptibility gene for atopic dermatitis...