Karolinska Institutet

Summary

Organization: Karolinska Institutet
Country: Sweden

Top Publications

  1. pmc A recombinant vaccine effectively induces c5a-specific neutralizing antibodies and prevents arthritis
    Kutty Selva Nandakumar
    Medical Inflammation Research, Department of Experimental Medicine, Lund University, Lund, Sweden
    PLoS ONE 5:e13511. 2010
  2. doi Genetic aspects of cluster headache
    Christina Sjöstrand
    Department of Clinical Neuroscience, Karolinska Institute, Karolinska University Hospital, Stockholm, Sweden
    Expert Rev Neurother 9:359-68. 2009
  3. doi Tracing immunity to human leishmaniasis
    Susanne Nylen
    Department of Microbiology, Tumor Biology and Cell Biology, Karolinska Institute, Stockholm, Sweden
    Future Microbiol 4:241-54. 2009
  4. doi A modified epitope identified for generation and monitoring of PSA-specific T cells in patients on early phases of PSA-based immunotherapeutic protocols
    Kajsa Lundberg
    Department of Oncology and Pathology, Cancer Center Karolinska R8 01, Immune and Gene Therapy Laboratory, Karolinska Institute, 171 76 Stockholm, Sweden
    Vaccine 27:1557-65. 2009
  5. doi Long-term dietary acrylamide intake and breast cancer risk in a prospective cohort of Swedish women
    Susanna C Larsson
    Division of Nutritional Epidemiology, National Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    Am J Epidemiol 169:376-81. 2009
  6. doi Short stature, smoking habits and birth outcome in international adoptees in Sweden
    Cecilia Ekeus
    Department of Woman and Child Health, Division of Reproductive and Perinatal Health, Karolinska Institutet, Stockholm, Sweden
    Acta Obstet Gynecol Scand 87:1309-14. 2008
  7. pmc Perceived needs and satisfaction with care in people with multiple sclerosis: a two-year prospective study
    Charlotte Ytterberg
    Department of Clinical Neuroscience, and Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden
    BMC Neurol 8:36. 2008
  8. doi Collateral reinnervation by the superior laryngeal nerve after recurrent laryngeal nerve injury
    Jonas Hydman
    Department of Clinical Neuroscience, Section of Neurosurgery R2 02, Karolinska Institute, S 171 76 Stockholm, Sweden
    Muscle Nerve 38:1280-9. 2008
  9. ncbi [Management of thrombocyte inhibitors prior to surgery. Too early withdrawal can result in severe risks for the patient]
    Michael Lagerkranser
    Karolinska Institutet
    Lakartidningen 105:2188-9. 2008
  10. doi CPOE in Iran--a viable prospect? Physicians' opinions on using CPOE in an Iranian teaching hospital
    Alireza Kazemi
    Department of Learning, Informatics, Management and Ethics LIME, Karolinska Institutet, Stockholm, Sweden
    Int J Med Inform 78:199-207. 2009

Research Grants

Detail Information

Publications62

  1. pmc A recombinant vaccine effectively induces c5a-specific neutralizing antibodies and prevents arthritis
    Kutty Selva Nandakumar
    Medical Inflammation Research, Department of Experimental Medicine, Lund University, Lund, Sweden
    PLoS ONE 5:e13511. 2010
    ..To develop and validate a recombinant vaccine to attenuate inflammation in arthritis by sustained neutralization of the anaphylatoxin C5a...
  2. doi Genetic aspects of cluster headache
    Christina Sjöstrand
    Department of Clinical Neuroscience, Karolinska Institute, Karolinska University Hospital, Stockholm, Sweden
    Expert Rev Neurother 9:359-68. 2009
    ..Collaborative multicenter studies on large clinically well-defined materials are needed to reach a better understanding of the complex genetic background of CH...
  3. doi Tracing immunity to human leishmaniasis
    Susanne Nylen
    Department of Microbiology, Tumor Biology and Cell Biology, Karolinska Institute, Stockholm, Sweden
    Future Microbiol 4:241-54. 2009
    ....
  4. doi A modified epitope identified for generation and monitoring of PSA-specific T cells in patients on early phases of PSA-based immunotherapeutic protocols
    Kajsa Lundberg
    Department of Oncology and Pathology, Cancer Center Karolinska R8 01, Immune and Gene Therapy Laboratory, Karolinska Institute, 171 76 Stockholm, Sweden
    Vaccine 27:1557-65. 2009
    ....
  5. doi Long-term dietary acrylamide intake and breast cancer risk in a prospective cohort of Swedish women
    Susanna C Larsson
    Division of Nutritional Epidemiology, National Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    Am J Epidemiol 169:376-81. 2009
    ..These findings for Swedish women do not support the hypothesis that dietary acrylamide is positively associated with risk of breast cancer, at least not within the ranges of acrylamide consumed by this population...
  6. doi Short stature, smoking habits and birth outcome in international adoptees in Sweden
    Cecilia Ekeus
    Department of Woman and Child Health, Division of Reproductive and Perinatal Health, Karolinska Institutet, Stockholm, Sweden
    Acta Obstet Gynecol Scand 87:1309-14. 2008
    ..To investigate short stature and smoking habits as risk factors for birth outcome in international adoptees in comparison with non-adopted mothers...
  7. pmc Perceived needs and satisfaction with care in people with multiple sclerosis: a two-year prospective study
    Charlotte Ytterberg
    Department of Clinical Neuroscience, and Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden
    BMC Neurol 8:36. 2008
    ..The aim was to explore the perceived needs and satisfaction with care amongst PwMS over a two-year period, also taking sex and disease severity into consideration...
  8. doi Collateral reinnervation by the superior laryngeal nerve after recurrent laryngeal nerve injury
    Jonas Hydman
    Department of Clinical Neuroscience, Section of Neurosurgery R2 02, Karolinska Institute, S 171 76 Stockholm, Sweden
    Muscle Nerve 38:1280-9. 2008
    ..This may be important when choosing surgical and/or medical treatment for patients with RLN injury...
  9. ncbi [Management of thrombocyte inhibitors prior to surgery. Too early withdrawal can result in severe risks for the patient]
    Michael Lagerkranser
    Karolinska Institutet
    Lakartidningen 105:2188-9. 2008
  10. doi CPOE in Iran--a viable prospect? Physicians' opinions on using CPOE in an Iranian teaching hospital
    Alireza Kazemi
    Department of Learning, Informatics, Management and Ethics LIME, Karolinska Institutet, Stockholm, Sweden
    Int J Med Inform 78:199-207. 2009
    ..Understanding the current prescription process and a proper needs assessment of prescribers can act as the key to successful implementation...
  11. doi Reflecting peer-support groups in the prevention of stress and burnout: randomized controlled trial
    Ulla Peterson
    Department of Clinical Neuroscience, Section for Personal Injury Prevention, Karolinska Institute, Stockholm, Sweden
    J Adv Nurs 63:506-16. 2008
    ..This paper is a report of a study to test the effect of participating in a reflecting peer-support group on self-reported health, burnout and on perceived changes in work conditions...
  12. doi Timing-dependent effects of restraint stress on eosinophilic airway inflammation in mice
    S Kumlien Georén
    Division of ENT Diseases, Department of Clinical Science, Intervention and Technology, Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden
    Neuroimmunomodulation 15:157-64. 2008
    ..The aim of this study was to investigate the influence of timing of single short restraint stress (RST) in a model of eosinophilic airway inflammation...
  13. doi Women with non-Swedish speaking background and their children: a longitudinal study of uptake of care and maternal and child health
    Helena Fabian
    Department of Woman and Child Health, Karolinska Institutet, Stockholm, Sweden
    Acta Paediatr 97:1721-8. 2008
    ..To study uptake of care at the antenatal and child health clinic (CHC), and maternal and child health up to 5 years after the birth, as reported by mothers with a non-Swedish speaking background (NSB)...
  14. doi Mechanisms of fatigue induced by isometric contractions in exercising humans and in mouse isolated single muscle fibres
    Nicolas Place
    Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden
    Clin Exp Pharmacol Physiol 36:334-9. 2009
    ..To further increase the understanding of fatigue mechanisms in humans, we propose future studies using in vitro stimulation patterns that are closer to the in vivo situation...
  15. doi 25-hydroxyvitamin D accumulation during summer in elderly women at latitude 60 degrees N
    Ann Burgaz
    Division of Nutritional Epidemiology, Institute of Environmental Medicine, Karolinska Institute, Stockholm, Sweden
    J Intern Med 266:476-83. 2009
    ..During April to September, 25(OH)D status may be improved by solar exposure. In this study, we measured seasonal differences in serum 25(OH)D concentrations and identified the major predictors of summer 25(OH)D concentrations...
  16. doi Separate and overlapping metabolic functions of LXRalpha and LXRbeta in C57Bl/6 female mice
    Marion Korach-Andre
    Dept of Biosciences and Nutrition, Karolinska Institutet, S 141 57 Huddinge, Sweden
    Am J Physiol Endocrinol Metab 298:E167-78. 2010
    ..We conclude that selective LXRbeta agonists would be novel pharmaceuticals in the treatment of T2D...
  17. doi Local delivery of hyaluronan as an adjunct to scaling and root planing in the treatment of chronic periodontitis
    Annsofi Johannsen
    Dental Hygiene Program and Department of Periodontology, Institute of Odontology, Karolinska Institute, Huddinge, Sweden
    J Periodontol 80:1493-7. 2009
    ..The aim of the present study was to evaluate the adjunctive effect of the local application of a hyaluronan gel to scaling and root planing in the treatment of chronic periodontitis...
  18. pmc Inhibition of lipid antigen presentation in dendritic cells by HIV-1 Vpu interference with CD1d recycling from endosomal compartments
    Markus Moll
    Center for Infectious Medicine, Department of Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden
    Blood 116:1876-84. 2010
    ....
  19. doi Remodeling in asthma and COPD--differences and similarities
    C Magnus Skold
    Department Medicine, Division of Respiratory Medicine, Karolinska Institutet, Karolinska University Hospital Solna, Stockholm, Sweden
    Clin Respir J 4:20-7. 2010
    ..However, both asthma and COPD are heterogeneous disorders including various phenotypes and there is a considerable overlap between the two diseases...
  20. doi Comparison of analytical approaches for liquid chromatography/mass spectrometry determination of the alcohol biomarker ethyl glucuronide in urine
    Anders Helander
    Karolinska Institutet, Department of Laboratory Medicine, Stockholm, Sweden
    Rapid Commun Mass Spectrom 24:1737-43. 2010
    ..These results indicate that the likelihood of different analytical methods to provide reliable analytical results depends on the reporting limit applied...
  21. doi Migraine and olfactory stimuli
    Christina Sjöstrand
    Headache Research Centre, Department of Clinical Neuroscience, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden
    Curr Pain Headache Rep 14:244-51. 2010
    ..Migraine pathophysiology likely explains this particular vulnerability. We discuss these pathophysiologic mechanisms and hypotheses relating odour intolerances and migraine...
  22. doi Primary hyperparathyroidism in pregnancy: a diagnostic and therapeutic challenge
    I L Nilsson
    Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden
    J Womens Health (Larchmt) 19:1117-21. 2010
    ..Our two cases illustrate both the importance of and the difficulty in detecting pHPT during pregnancy, as well as some of the serious complications that may occur during pregnancy and after delivery...
  23. doi Changes in perceived health between one and five years after stroke: a randomized controlled trial of early supported discharge with continued rehabilitation at home versus conventional rehabilitation
    Charlotte Ytterberg
    Karolinska Institutet, Department of Neurobiology, Care Sciences and Society, Division of Physiotherapy, Fack 23 100, 141 83 Huddinge, Sweden
    J Neurol Sci 294:86-8. 2010
    ..The aim of this study was to explore changes over time in perceived health status over the five years after stroke onset...
  24. doi Influence of oral contraceptives on endogenous pain control in healthy women
    Taraneh Rezaii
    Division of Clinical Oral Physiology, Department of Dental Medicine, Karolinska Institutet, Box 4064, SE 141 04, Huddinge, Sweden
    Exp Brain Res 203:329-38. 2010
    ..027). There were no significant differences between groups or sessions in estradiol levels. These results indicate that endogenous pain modulation may be less effective in OC users...
  25. doi Balancing the good - a critical discourse analysis of home modification services
    Karin Johansson
    Department of Neurobiology, Caring Sciences and Society, Division of Occupational Therapy, Karolinska Institutet, Stockholm, Sweden
    Sociol Health Illn 32:563-82. 2010
    ..Understanding the moral dimensions that enter into the complexity of allocation of home modification services across institutional settings has implications for the policies of and practices for the allocation of welfare resources...
  26. doi Sex differences in the incidence of gastrointestinal adenocarcinoma in Sweden 1970-2006
    Martin Rutegård
    Upper GastroIntestinal Research UGIR, Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden
    Eur J Cancer 46:1093-100. 2010
    ..An endogenous factor, such as premenopausal oestrogen exposure, may act protectively in favour of women and might be detected by scrutinising sex ratios and incidence rates stratified by age...
  27. pmc Amygdala-dependent fear conditioning in humans is modulated by the BDNFval66met polymorphism
    Tina B Lonsdorf
    Department of Clinical Neuroscience, Psychology Section, Stockholm Brain Institute, Karolinska Institutet
    Behav Neurosci 124:9-15. 2010
    ..We suggest that the BDNF met-allele may have a protective effect for the development of affective pathologies that may be mediated via reduced synaptic plasticity induced by negative experience...
  28. doi Health effects of a subway environment in healthy volunteers
    A Klepczynska Nyström
    Dept of Public Health Sciences, Division of Occupational and Environmental Medicine, Karolinska Institutet, Norrbacka, 4th Floor, SE 17176 Stockholm, Sweden
    Eur Respir J 36:240-8. 2010
    ..Our studies show that using gravimetric estimates of ambient particulate air pollution alone may have clear limitations in health-risk assessment...
  29. doi Visfatin is increased in chronic kidney disease patients with poor appetite and correlates negatively with fasting serum amino acids and triglyceride levels
    Juan J Carrero
    Divisions of Renal Medicine and Baxter Novum, Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden
    Nephrol Dial Transplant 25:901-6. 2010
    ..We hypothesized that increased visfatin levels in CKD patients may be involved in the regulation of appetite and nutrient homeostasis...
  30. ncbi Comparison of protein expression in two prostate cancer cell-lines, LNCaP and DU145, after treatment with somatostatin
    Zhaoxu Liu
    Department of Urology, Qilu Hospital School of Nursing, Shandong University, Jinan, PR China
    Oncol Rep 22:1451-8. 2009
    ..Regulation of certain proteins (e.g., RKIP, VDACs) by sms/smsdx suggests that sms/smsdx exerts its effects on prostate cancer cells via MAPK pathway and by regulating the activities of phosphotyrosine phosphatases...
  31. pmc Association of physical activity with cancer incidence, mortality, and survival: a population-based study of men
    N Orsini
    Division of Nutritional Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    Br J Cancer 98:1864-9. 2008
    ..Our results suggest that higher levels of PA and the main component of active living, walking or bicycling are associated with reduced cancer incidence and mortality, as well as higher cancer survival...
  32. doi Introduction: Inflammatory bowel disease: a complex systemic disease engaging multiple players outside the immune system
    S Pettersson
    Division of Molecular Pathology, Karolinska Institutet, Stockholm, Sweden
    J Intern Med 263:574-6. 2008
  33. ncbi [MET: an intensive care (r)evolution. Strong medical and ethical reasons for introducing a mobile emergency team]
    David Konrad
    Centrala intensivvårdsavdelningen, Karolinska Universitetssjukhuset Solna, Stockholm
    Lakartidningen 103:3594-5. 2006
  34. ncbi Association analysis of the LAG3 and CD4 genes in multiple sclerosis in two independent populations
    Frida Lundmark
    Division of Neurology, Department of Clinical Neuroscience, Karolinska Institutet at Karolinska University Hospital, Huddinge, Stockholm, Sweden
    J Neuroimmunol 180:193-8. 2006
    ..The result, including a total of 2640 MS patients and 2194 controls shows no significant association with CD4 and LAG3 and MS. We conclude that these genes are of minor importance in regard of genetic predisposition to the MS...
  35. ncbi Specificity and effector mechanisms of autoantibodies in congenital heart block
    Marie Wahren-Herlenius
    Rheumatology Unit, Department of Medicine, Karolinska Institutet, SE 171 76 Stockholm, Sweden
    Curr Opin Immunol 18:690-6. 2006
    ..Early intrauterine treatment of an incomplete AV-block with fluorinated steroids has been shown to prevent progression of the heart block, making it clinically important to find specific markers to identify the high-risk pregnancies...
  36. ncbi Interpreting trends in cancer patient survival
    P W Dickman
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden, and Department of Epidemiology, Harvard University, Boston, MA, USA
    J Intern Med 260:103-17. 2006
    ..Our aim was to lay out the strengths and limitations of survival analysis as a tool in the evaluation of progress in the diagnosis and treatment of cancer...
  37. pmc Corticotropin-releasing hormone, its binding protein and receptors in human cervical tissue at preterm and term labor in comparison to non-pregnant state
    Aurelija Klimaviciute
    Dept of Woman and Child Health, Karolinska Institute, Stockholm, Sweden
    Reprod Biol Endocrinol 4:29. 2006
    ....
  38. ncbi Mitral valve insufficiency and left ventricular remodeling in identical twins
    Anders Franco-Cereceda
    Department of Cardiothoracic Surgery and Anaesthesia, Karolinska University Hospital, Stockholm, Sweden
    J Thorac Cardiovasc Surg 131:1400-1. 2006
  39. ncbi Mesenchymal stem cells are susceptible to human herpesviruses, but viral DNA cannot be detected in the healthy seropositive individual
    M Sundin
    Division of Clinical Immunology, Department of Laboratory Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, SE 141 86 Stockholm, Sweden
    Bone Marrow Transplant 37:1051-9. 2006
    ..However, MSC may be susceptible to infection if infused in a patient with CMV or HSV-1 viremia. MSC transplantation may compromise the host's defense against infectious agents...
  40. ncbi Brain-derived neurotrophic factor gene (BDNF) variants and schizophrenia: an association study
    Erik G Jonsson
    Department of Clinical Neuroscience, HUBIN project, Karolinska Institutet and Hospital, R5 00, SE 171 76 Stockholm, Sweden
    Prog Neuropsychopharmacol Biol Psychiatry 30:924-33. 2006
    ..Thus, the BDNF gene may confer susceptibility to schizophrenia. Additional studies are warranted to shed further light on this possibility...
  41. ncbi The XPD 751Gln allele is associated with an increased risk for esophageal adenocarcinoma: a population-based case-control study in Sweden
    Weimin Ye
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, SE 171 77, Sweden
    Carcinogenesis 27:1835-41. 2006
    ..Other studied variants were not found to be related to the three tumors. Our study suggests that XPD 751Gln allele is a potential genetic marker for susceptibility to esophageal adenocarcinoma...
  42. ncbi Substitution of bovine dentine sialoprotein with chondroitin sulfate glycosaminoglycan chains
    Rachael V Sugars
    Centre for Oral Biology, Karolinska Institutet, Institute of Odontology, Sweden
    Eur J Oral Sci 114:89-92. 2006
    ..These results support the classification of bovine DSP as a proteoglycan, and that the carbohydrate substitutions may contribute to the functional properties of DSP...
  43. pmc Lack of interchangeability between visual analogue and verbal rating pain scales: a cross sectional description of pain etiology groups
    Irene Lund
    Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, SE 171 77, Sweden
    BMC Med Res Methodol 5:31. 2005
    ..Interchangeability of recorded pain intensity captured in the two scales has been discussed earlier, but not in conjunction with taking the influence of pain etiology into consideration...
  44. ncbi MIC determination of fusidic acid and of ciprofloxacin using multidisk diffusion tests
    G Kronvall
    Clinical Microbiology MTC, Karolinska Institute, Karolinska Hospitals, Stockholm, Sweden
    Clin Microbiol Infect 6:483-9. 2000
    ..To investigate the possibility of estimating the MICs of fusidic acid and ciprofloxacin for bacterial isolates using series of antibiotic disk concentrations in diffusion tests, so-called M-tests...
  45. ncbi Isolation and chromosomal localization of a new human retinoblastoma binding protein 2 homologue 1a (RBBP2H1A)
    V Kashuba
    Microbiology and Tumor Biology Center, Karolinska Institute, Stockholm, Sweden
    Eur J Hum Genet 8:407-13. 2000
    ..The mRNA sizes corresponding to two major products are around 6kb and 7kb. Using fluorescence in situ hybridization, we mapped the gene to chromosomal band 1q32.1...
  46. ncbi New roles for an old enzyme: Na,K-ATPase emerges as an interesting drug target
    A Aperia
    Department of Woman and Child Health, Karolinska Institutet, Stockholm, Sweden
    J Intern Med 261:44-52. 2007
    ..This review will present these new aspects of NKA and their clinical implications...
  47. ncbi Airborne exposures and risk of gastric cancer: a prospective cohort study
    Krister Sjödahl
    Unit of Esophageal and Gastric Research ESOGAR, Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden
    Int J Cancer 120:2013-8. 2007
    ..In conclusion, this study provides some support to the hypothesis that specific airborne exposures increase the risk of noncardia gastric cancer...
  48. ncbi Risk factors for Barrett's oesophagus: a population-based approach
    Johan Johansson
    Department of Surgery, Kalmar County Hospital, Sweden
    Scand J Gastroenterol 42:148-56. 2007
    ..The objective of this study was to investigate risk factors for incident BO diagnosed in a defined population in southeast Sweden while paying particular attention to epidemiological aspects of the study design...
  49. doi No detectable endothelial- or leukocyte-derived L-selectin ligand activity on the endothelium in inflamed cremaster muscle venules
    Einar E Eriksson
    Department of Physiology and Pharmacology, Karolinska Institutet, S 171 77 Stockholm, Sweden
    J Leukoc Biol 84:93-103. 2008
    ..These data demonstrate that expression of L-selectin on leukocytes is insufficient for mediating rolling and efficient recruitment of leukocytes in inflammation...
  50. ncbi [Health care information systems at a crucial turning-point]
    Ingvar Krakau
    Karolinska Institutet
    Lakartidningen 105:301-3. 2008
  51. ncbi [Diseases of the aortic valve and ascending aorta. Valve-sparing surgery should be considered primarily]
    Anders Franco-Cereceda
    Karolinska Universitetssjukhuset Solna, Stockholm
    Lakartidningen 105:434-7. 2008
  52. doi Contextual social capital as a risk factor for poor self-rated health: a multilevel analysis
    Karin Engström
    Karolinska Institutet, Department of Public Health Sciences, Stockholm, Sweden
    Soc Sci Med 66:2268-80. 2008
    ..The association with self-rated health is similar independent of the measure of CSC used. It is also similar in different socio-demographic groups...
  53. pmc Sub-grouping and sub-functionalization of the RIFIN multi-copy protein family
    Nicolas Joannin
    Department of Microbiology, Tumor and Cell Biology MTC, Karolinska Institutet, SE 17177 Stockholm, Sweden and Swedish Institute for Infectious Diseases Control, SE 17182 Stockholm, Sweden
    BMC Genomics 9:19. 2008
    ....
  54. doi Effects of neighbourhood and individual factors on injury risk in the entire Swedish population: a 12-month multilevel follow-up study
    Xinjun Li
    Center for Family and Community Medicine, Department of Neurobiology, Caring Sciences and Society, Karolinska Institutet, Alfred Nobels alle 12, 141 83, Huddinge, Sweden
    Eur J Epidemiol 23:191-203. 2008
    ..Our results suggest that interventions focused on contextual aspects of neighbourhoods, in addition to individual behaviours, may have a positive impact on injury prevention...
  55. ncbi Metabolism of antidepressant and neuroleptic drugs by cytochrome p450s: clinical and interethnic aspects
    L Bertilsson
    Division of Clinical Pharmacology, Department of Laboratory Medicine at Karolinska Institutet, Karolinska University Hospital, Huddinge, Stockholm, Sweden
    Clin Pharmacol Ther 82:606-9. 2007
    ..This brief review highlights the clinical importance and ethnic differences in the metabolism of these drugs...
  56. ncbi Social isolation increases number of newly proliferated cells in hippocampus in female flinders sensitive line rats
    Astrid Bjørnebekk
    Department of Neuroscience, Karolinska Institutet, SE 171 77 Stockholm, Sweden
    Hippocampus 17:1193-200. 2007
    ..We demonstrate strain and gender specific responses to stress induced regulation of factors important for hippocampal plasticity...
  57. ncbi Rectal nitric oxide and fecal calprotectin in inflammatory bowel disease
    Claudia A Reinders
    Department of Physiology and Pharmacology Karolinska Institutet, Stockholm, Sweden
    Scand J Gastroenterol 42:1151-7. 2007
    ..Both rectal nitric oxide (NO) and fecal calprotectin can be measured using non-invasive methods and are emerging as promising inflammatory markers in IBD. In this study the aim was to compare calprotectin and NO levels in IBD patients...
  58. ncbi Secular trends of nasopharyngeal carcinoma incidence in Singapore, Hong Kong and Los Angeles Chinese populations, 1973-1997
    Juhua Luo
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Nobels vag 12a, Box 281, 171 77, Stockholm, Sweden
    Eur J Epidemiol 22:513-21. 2007
    ..This indicates that environmental and lifestyle changes play an important role in the declining incidence of NPC over time...
  59. ncbi The role of neutral lipases in human adipose tissue lipolysis
    Peter Arner
    Karolinska Institute at the Department of Medicine, Karolinska University Hospital, Huddinge, Stockholm, Sweden
    Curr Opin Lipidol 18:246-50. 2007
    ..The aim of this article is to describe the relative roles of hormone sensitive lipase and adipose triglyceride lipase in human fat cell lipolysis...
  60. ncbi Testing association in the presence of linkage--a powerful score for binary traits
    Gudrun Jonasdottir
    Department of Medical Epidemiology and Biostatistics, Karolinska Institute, S 17177 Stockholm, Sweden
    Genet Epidemiol 31:528-40. 2007
    ..We apply the method to data from the Collaborative Study on the Genetics of Alcoholism. We compare our findings to previously published results...
  61. pmc Newly recruited human monocytes have a preserved responsiveness towards bacterial peptides in terms of CD11b up-regulation and intracellular hydrogen peroxide production
    E Dadfar
    Department of Medicine, Clinical Immunology and Allergy Unit, Karolinska Institutet, Karolinska University Hospital, Sweden
    Clin Exp Immunol 148:573-82. 2007
    ..These data strengthen a role for newly recruited interstitial human monocytes in the immediate defence against invading pathogens...
  62. ncbi The clonal composition of a peptide-specific oligoclonal CTL repertoire selected in response to persistent EBV infection is stable over time
    V Levitsky
    Microbiology and Tumorbiology Center, Karolinska Institute, Stockholm, Sweden
    J Immunol 161:594-601. 1998
    ..Our results suggest that competition for the specific Ag may be not the major force driving the maintenance of memory CTLs and that the nature of the first antigenic challenge may largely determine the clonal composition of memory...

Research Grants9

  1. Hormone markers during pregnancy and ovarian concer risk
    Sven Cnattingius; Fiscal Year: 2005
    ..The Swedish research registers will allow us to perform a large cost-effective cohort study where information on markers of hormone exposure during pregnancy has been collected prospectively. ..
  2. NEPHRIN AND KIDNEY FUNCTION AND DISEASE
    Karl Tryggvason; Fiscal Year: 2001
    ....
  3. Genetic determinants of postmenopausal breast cancer
    Per Hall; Fiscal Year: 2009
    ..In addition, by using haplotype-tagging SNPs (ht-SNPs), we reduce the genotyping load by approximately 75%, while retaining thorough characterization of each gene under evaluation. ..