Bjorn Holmberg

Summary

Country: Sweden

Publications

  1. ncbi request reprint CSF-neurofilament and levodopa tests combined with discriminant analysis may contribute to the differential diagnosis of Parkinsonian syndromes
    B Holmberg
    Institute of Clinical Neuroscience, Department of Neurology, University of Goteborg, Sahlgrenska University Hospital, 413 45, Sweden
    Parkinsonism Relat Disord 8:23-31. 2001
  2. ncbi request reprint Safety and tolerability of growth hormone therapy in multiple system atrophy: a double-blind, placebo-controlled study
    Bjorn Holmberg
    Movement Disorders Unit, Sahlgrenska University Hospital, Goteborg University, Goteborg, Sweden
    Mov Disord 22:1138-44. 2007
  3. ncbi request reprint Cerebrospinal fluid Abeta42 is reduced in multiple system atrophy but normal in Parkinson's disease and progressive supranuclear palsy
    Bjorn Holmberg
    Institute of Clinical Neuroscience, Goteborg University, Sahlgrenska University Hospital, Goteborg, Sweden
    Mov Disord 18:186-90. 2003
  4. ncbi request reprint Bilateral stimulation of nucleus subthalamicus in advanced Parkinson's disease: no effects on, and of, autonomic dysfunction
    Bjorn Holmberg
    Institute for Clinical Neuroscience, Sahlgrenska Academy, Gothenburg University, Sweden
    Mov Disord 20:976-81. 2005
  5. ncbi request reprint Investigation of genes coding for inflammatory components in Parkinson's disease
    Anna Håkansson
    Department of Pharmacology, Sahlgrenska Academy at Goteborg University, Goteborg, Sweden
    Mov Disord 20:569-73. 2005
  6. ncbi request reprint Cyclooxygenase-2 polymorphisms in Parkinson's disease
    Anna Håkansson
    Department of Pharmacology, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at Goteborg University, Goteborg, Sweden
    Am J Med Genet B Neuropsychiatr Genet 144:367-9. 2007
  7. doi request reprint Consecutive analyses of cerebrospinal fluid axonal and glial markers in Parkinson's disease and atypical Parkinsonian disorders
    Radu Constantinescu
    Department of Neurology, Sahlgrenska University Hospital, 413 45 Goteborg, Sweden
    Parkinsonism Relat Disord 16:142-5. 2010
  8. ncbi request reprint Simultaneous measurement of beta-amyloid(1-42), total tau, and phosphorylated tau (Thr181) in cerebrospinal fluid by the xMAP technology
    Annika Olsson
    Institute of Clinical Neuroscience, Sahlgrenska University Hospital, Molndal, Sweden
    Clin Chem 51:336-45. 2005
  9. doi request reprint Proteomic profiling of cerebrospinal fluid in parkinsonian disorders
    Radu Constantinescu
    Institute of Neuroscience and Physiology, Department of Neurology, The Sahlgrenska Academy at the University of Gothenburg, 413 45 Goteborg, Sweden
    Parkinsonism Relat Disord 16:545-9. 2010
  10. doi request reprint Levels of brain related proteins in cerebrospinal fluid: an aid in the differential diagnosis of parkinsonian disorders
    Radu Constantinescu
    Department of Neurology, Sahlgrenska University Hospital, 413 45 Goteborg, Sweden
    Parkinsonism Relat Disord 15:205-12. 2009

Detail Information

Publications14

  1. ncbi request reprint CSF-neurofilament and levodopa tests combined with discriminant analysis may contribute to the differential diagnosis of Parkinsonian syndromes
    B Holmberg
    Institute of Clinical Neuroscience, Department of Neurology, University of Goteborg, Sahlgrenska University Hospital, 413 45, Sweden
    Parkinsonism Relat Disord 8:23-31. 2001
    ..As they are pathologically unrelated, the diagnostic precision increases compared to clinical diagnoses when they are combined...
  2. ncbi request reprint Safety and tolerability of growth hormone therapy in multiple system atrophy: a double-blind, placebo-controlled study
    Bjorn Holmberg
    Movement Disorders Unit, Sahlgrenska University Hospital, Goteborg University, Goteborg, Sweden
    Mov Disord 22:1138-44. 2007
    ..In conclusion, r-hGH administration in MSA patients for up to 1 year appears safe and might influence disease symptoms, signs and, possibly, progression. The results support further studies utilizing higher doses in more patients...
  3. ncbi request reprint Cerebrospinal fluid Abeta42 is reduced in multiple system atrophy but normal in Parkinson's disease and progressive supranuclear palsy
    Bjorn Holmberg
    Institute of Clinical Neuroscience, Goteborg University, Sahlgrenska University Hospital, Goteborg, Sweden
    Mov Disord 18:186-90. 2003
    ..There is a decreased production, or more possible, an increased consumption of CSF-Abeta42. The analysis of this protein may also become a supplement to the clinical differentiation of parkinsonian syndromes in a movement disorder unit...
  4. ncbi request reprint Bilateral stimulation of nucleus subthalamicus in advanced Parkinson's disease: no effects on, and of, autonomic dysfunction
    Bjorn Holmberg
    Institute for Clinical Neuroscience, Sahlgrenska Academy, Gothenburg University, Sweden
    Mov Disord 20:976-81. 2005
    ..Preoperative cardiovascular autonomic reflex dysfunction, conversely, does not exclude an excellent stimulation effect...
  5. ncbi request reprint Investigation of genes coding for inflammatory components in Parkinson's disease
    Anna Håkansson
    Department of Pharmacology, Sahlgrenska Academy at Goteborg University, Goteborg, Sweden
    Mov Disord 20:569-73. 2005
    ..The results indicate that the IL-10 G1082A SNP could possibly be related to the age of onset of PD...
  6. ncbi request reprint Cyclooxygenase-2 polymorphisms in Parkinson's disease
    Anna Håkansson
    Department of Pharmacology, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at Goteborg University, Goteborg, Sweden
    Am J Med Genet B Neuropsychiatr Genet 144:367-9. 2007
    ..007). In females no difference could be seen between PD-patients and controls. In conclusion, the results suggest a possible influence of the COX-2 C8473T SNP in PD, although it only seems to be of importance in men...
  7. doi request reprint Consecutive analyses of cerebrospinal fluid axonal and glial markers in Parkinson's disease and atypical Parkinsonian disorders
    Radu Constantinescu
    Department of Neurology, Sahlgrenska University Hospital, 413 45 Goteborg, Sweden
    Parkinsonism Relat Disord 16:142-5. 2010
    ..Our results suggest that measurements of CSF NFL but not GFAP can be useful in the differential diagnosis of PD versus atypical parkinsonian disorders (APD). However they do not help differentiate between the different APD...
  8. ncbi request reprint Simultaneous measurement of beta-amyloid(1-42), total tau, and phosphorylated tau (Thr181) in cerebrospinal fluid by the xMAP technology
    Annika Olsson
    Institute of Clinical Neuroscience, Sahlgrenska University Hospital, Molndal, Sweden
    Clin Chem 51:336-45. 2005
    ....
  9. doi request reprint Proteomic profiling of cerebrospinal fluid in parkinsonian disorders
    Radu Constantinescu
    Institute of Neuroscience and Physiology, Department of Neurology, The Sahlgrenska Academy at the University of Gothenburg, 413 45 Goteborg, Sweden
    Parkinsonism Relat Disord 16:545-9. 2010
    ..However, they could not differentiate PD patients from controls. As none of these changes were APD subgroup-specific, they most likely reflect the intensity and/or extent of the neurodegenerative process in general...
  10. doi request reprint Levels of brain related proteins in cerebrospinal fluid: an aid in the differential diagnosis of parkinsonian disorders
    Radu Constantinescu
    Department of Neurology, Sahlgrenska University Hospital, 413 45 Goteborg, Sweden
    Parkinsonism Relat Disord 15:205-12. 2009
    ..A review of the literature shows that, carefully interpreted, the CSF levels of BRP can be of value in the differential diagnosis of parkinsonian disorders...
  11. doi request reprint Key clinical milestones 15 years and onwards after DBS-STN surgery-A retrospective analysis of patients that underwent surgery between 1993 and 2001
    Radu Constantinescu
    Department of Neurology, Institute of Neuroscience and Physiology at Sahlgrenska Academy, University of Gothenburg, Sahlgrenska University Hospital, 413 45 Goteborg, Sweden Electronic address
    Clin Neurol Neurosurg 154:43-48. 2017
    ..In this paper we investigated patients with advanced PD operated at our center with STN-DBS for at least 15 years ago, in respect to key clinical milestones reflecting their overall function in daily living...
  12. ncbi request reprint Interaction of polymorphisms in the genes encoding interleukin-6 and estrogen receptor beta on the susceptibility to Parkinson's disease
    Anna Håkansson
    Department of Pharmacology, Sahlgrenska Academy at Goteborg University, Goteborg, Sweden
    Am J Med Genet B Neuropsychiatr Genet 133:88-92. 2005
    ..Our results indicate that the G-174C SNP in the IL-6 promoter may influence the risk for developing PD, particularly regarding early age of onset PD, and that the effect is modified by interaction of the G-1730A SNP in the ERbeta gene...
  13. ncbi request reprint Parkinson-plus patients--an unknown group with severe symptoms
    Anne Christine Sjöström
    Neurological Unit, Sahlgrenska University Hospital, Gothenburg, Sweden
    J Neurosci Nurs 34:314-9. 2002
    ..In accordance with palliative care philosophy, caregivers can help direct the patients' hope from cure to a palliative goal, with a focus on quality of life...
  14. ncbi request reprint Excellent outcome after prolonged status epilepticus due to non-paraneoplastic limbic encephalitis
    Daniel Kondziella
    Department of Neurology and Neurophysiology, Sahlgrenska University Hospital, Goteborg, Sweden
    Acta Neurol Belg 108:21-3. 2008
    ..Although this woman had prolonged status epilepticus during seven weeks, her outcome was excellent...