- The comet assay: mechanisms and technical considerationsM Klaude
Department of Radiobiology, Stockholm University, Sweden
Mutat Res 363:89-96. 1996..Further, the effects of alkaline concentration and sodium chloride during unwinding and electrophoresis are discussed. Throughout the study, a protocol for drying and fixation of the comets has been used...
- Effects of ethidium bromide on DNA loop organisation in human lymphocytes measured by anomalous viscosity time dependence and single cell gel electrophoresisI Y Belyaev
Department of Molecular Genome Research, Stockholm University, S 106 91, Stockholm, Sweden
Biochim Biophys Acta 1428:348-56. 1999..Further, the data show that the comet assay at neutral conditions of lysis is rather sensitive to DNA loop relaxation in the absence of DNA damage. Finally, donor specificity was found for the hypercondensation...
- The effect of dimethyl sulphoxide on the induction and repair of double-strand breaks in human cells after irradiation with gamma-rays and accelerated ions: rapid or slow repair may depend on accessibility of breaks in chromatin of different compactnessG Ahnstrom
Department of Molecular Genome Research, Stockholm University, Sweden
Int J Radiat Biol 76:533-8. 2000..To see if removal of OH radicals could remove part of the damage in complex dsb and make them easier to repair, human cells were irradiated in the presence of dimethyl sulphoxide (DMSO)...
- Dose-response for radiation-induced apoptosis, residual 53BP1 foci and DNA-loop relaxation in human lymphocytesJ Torudd
Department of Genetics, Microbiology and Toxicology, Stockholm University, Stockholm, Sweden
Int J Radiat Biol 81:125-38. 2005..The correlation between dose-responses obtained suggested that the DSB in residual foci and relaxation of DNA-loops may be linked to induction of radiation-induced apoptosis in lymphocytes...