Anders Gunnarsson

Summary

Affiliation: Chalmers University of Technology
Country: Sweden

Publications

  1. doi Kinetics of ligand binding to membrane receptors from equilibrium fluctuation analysis of single binding events
    Anders Gunnarsson
    Department of Applied Physics, Chalmers University of Technology, Göteborg, Sweden
    J Am Chem Soc 133:14852-5. 2011
  2. doi Time-resolved surface-enhanced ellipsometric contrast imaging for label-free analysis of biomolecular recognition reactions on glycolipid domains
    Anders Gunnarsson
    Department of Applied Physics, Division of Biological Physics, Chalmers University of Technology, SE 412 96 Goteborg, Sweden
    Anal Chem 84:6538-45. 2012
  3. doi Continuous lipid bilayers derived from cell membranes for spatial molecular manipulation
    Lisa Simonsson
    Department of Applied Physics, Chalmers University of Technology, Gothenburg, Sweden
    J Am Chem Soc 133:14027-32. 2011
  4. doi Accumulation and separation of membrane-bound proteins using hydrodynamic forces
    Peter Jonsson
    Department of Applied Physics, Chalmers University of Technology, SE 41296 Gothenburg, Sweden
    Anal Chem 83:604-11. 2011
  5. doi Equilibrium-fluctuation analysis for interaction studies between natural ligands and single G protein-coupled receptors in native lipid vesicles
    Olov Wahlsten
    Department of Applied Physics, Chalmers University of Technology, SE 41296 Gothenburg, Sweden
    Langmuir 31:10774-80. 2015
  6. doi Evanescent Light-Scattering Microscopy for Label-Free Interfacial Imaging: From Single Sub-100 nm Vesicles to Live Cells
    Björn Agnarsson
    Division of Biological Physics, Department of Applied Physics, Chalmers University of Technology, SE 41296 Goteborg, Sweden
    ACS Nano 9:11849-62. 2015
  7. doi Spatial-resolution limits in mass spectrometry imaging of supported lipid bilayers and individual lipid vesicles
    Anders Gunnarsson
    Department of Applied Physics, Division of Biological Physics, Chalmers University of Technology, SE 412 96 Goteborg, Sweden
    Anal Chem 82:2426-33. 2010
  8. doi Liposome-based chemical barcodes for single molecule DNA detection using imaging mass spectrometry
    Anders Gunnarsson
    Department of Applied Physics, Division of Biological Physics, Chalmers University of Technology, Goteborg, Sweden
    Nano Lett 10:732-7. 2010
  9. pmc Kinetic and thermodynamic characterization of single-mismatch discrimination using single-molecule imaging
    Anders Gunnarsson
    Department of Applied Physics, Chalmers University of Technology, SE 41296 Gothenburg, Sweden
    Nucleic Acids Res 37:e99. 2009
  10. doi Preserved transmembrane protein mobility in polymer-supported lipid bilayers derived from cell membranes
    Hudson Pace
    Department of Applied Physics, Chalmers University of Technology, SE 41296 Gothenburg, Sweden
    Anal Chem 87:9194-203. 2015

Collaborators

Detail Information

Publications11

  1. doi Kinetics of ligand binding to membrane receptors from equilibrium fluctuation analysis of single binding events
    Anders Gunnarsson
    Department of Applied Physics, Chalmers University of Technology, Göteborg, Sweden
    J Am Chem Soc 133:14852-5. 2011
    ..The single-molecule sensitivity made the analysis possible without overexpressed membrane proteins, which makes the assay attractive in early drug-screening applications...
  2. doi Time-resolved surface-enhanced ellipsometric contrast imaging for label-free analysis of biomolecular recognition reactions on glycolipid domains
    Anders Gunnarsson
    Department of Applied Physics, Division of Biological Physics, Chalmers University of Technology, SE 412 96 Goteborg, Sweden
    Anal Chem 84:6538-45. 2012
    ..The simplicity and generic applicability of the concept is discussed in terms of microfluidic applications...
  3. doi Continuous lipid bilayers derived from cell membranes for spatial molecular manipulation
    Lisa Simonsson
    Department of Applied Physics, Chalmers University of Technology, Gothenburg, Sweden
    J Am Chem Soc 133:14027-32. 2011
    ..Two populations of CTB with markedly different drift velocity could be identified, which from dissociation kinetics data were attributed to CTB bound with different numbers of ganglioside anchors...
  4. doi Accumulation and separation of membrane-bound proteins using hydrodynamic forces
    Peter Jonsson
    Department of Applied Physics, Chalmers University of Technology, SE 41296 Gothenburg, Sweden
    Anal Chem 83:604-11. 2011
    ..This was tentatively attributed to multivalent interactions between the protein and the monosialoganglioside G(M1) receptors in the lipid bilayer...
  5. doi Equilibrium-fluctuation analysis for interaction studies between natural ligands and single G protein-coupled receptors in native lipid vesicles
    Olov Wahlsten
    Department of Applied Physics, Chalmers University of Technology, SE 41296 Gothenburg, Sweden
    Langmuir 31:10774-80. 2015
    ....
  6. doi Evanescent Light-Scattering Microscopy for Label-Free Interfacial Imaging: From Single Sub-100 nm Vesicles to Live Cells
    Björn Agnarsson
    Division of Biological Physics, Department of Applied Physics, Chalmers University of Technology, SE 41296 Goteborg, Sweden
    ACS Nano 9:11849-62. 2015
    ..Taken together, these results underscore the versatility and general applicability of the method, which due to its simplicity and compatibility with conventional microscopy setups may reach a widespread in life science and beyond. ..
  7. doi Spatial-resolution limits in mass spectrometry imaging of supported lipid bilayers and individual lipid vesicles
    Anders Gunnarsson
    Department of Applied Physics, Division of Biological Physics, Chalmers University of Technology, SE 412 96 Goteborg, Sweden
    Anal Chem 82:2426-33. 2010
    ..Moreover, using 300 nm vesicles of different lipid composition, the capability to detect and chemically identify individual submicrometer lipid vesicles at separations down to approximately 1 microm is demonstrated...
  8. doi Liposome-based chemical barcodes for single molecule DNA detection using imaging mass spectrometry
    Anders Gunnarsson
    Department of Applied Physics, Division of Biological Physics, Chalmers University of Technology, Goteborg, Sweden
    Nano Lett 10:732-7. 2010
    ..Together with a high multiplexing capacity, this makes the concept an interesting alternative to existing barcode concepts based on fluorescence, Raman, or graphical codes for small-scale bioanalysis...
  9. pmc Kinetic and thermodynamic characterization of single-mismatch discrimination using single-molecule imaging
    Anders Gunnarsson
    Department of Applied Physics, Chalmers University of Technology, SE 41296 Gothenburg, Sweden
    Nucleic Acids Res 37:e99. 2009
    ..This suggests the method as a robust means for detection of point mutations at low target concentrations in, for example, single nucleotide polymorphism (SNP) analysis...
  10. doi Preserved transmembrane protein mobility in polymer-supported lipid bilayers derived from cell membranes
    Hudson Pace
    Department of Applied Physics, Chalmers University of Technology, SE 41296 Gothenburg, Sweden
    Anal Chem 87:9194-203. 2015
    ..The presented strategy could thus serve both fundamental studies of membrane biophysics and the production of surface-based bioanalytical sensor platforms. ..
  11. doi Drug discovery at the single molecule level: inhibition-in-solution assay of membrane-reconstituted β-secretase using single-molecule imaging
    Anders Gunnarsson
    Department of Applied Physics, Chalmers University of Technology, SE 412 96 Goteborg, Sweden
    Anal Chem 87:4100-3. 2015
    ..We demonstrate that the dynamic range of measurable affinities is greatly extended by more than 2 orders of magnitude as compared to SPR, thus facilitating measurements of highly potent (Kd < nM) compounds. ..