Nathalie Sumien

Summary

Publications

  1. pmc Does phytoestrogen supplementation affect cognition differentially in males and females?
    Nathalie Sumien
    Department of Pharmacology and Neuroscience, UNT Health Science Center at Fort Worth, Institute for Aging and Alzheimer s Disease Research, Fort Worth, TX 76107, USA
    Brain Res 1514:123-7. 2013
  2. pmc Reversible inactivation of dihydrolipoamide dehydrogenase by mitochondrial hydrogen peroxide
    Liang Jun Yan
    Department of Pharmacology and Neuroscience and Institute for Aging and Alzheimer s Disease Research, University of North Texas Health Science Center, Fort Worth, TX 76107, USA
    Free Radic Res 47:123-33. 2013
  3. pmc Prolonged intake of coenzyme Q10 impairs cognitive functions in mice
    Nathalie Sumien
    Department of Pharmacology and Neuroscience, Institute for Aging and Alzheimer s Disease Research, University of North Texas Health Science Center, Fort Worth, TX 76107, USA
    J Nutr 139:1926-32. 2009
  4. pmc Coenzyme Q(10) supplementation reverses age-related impairments in spatial learning and lowers protein oxidation
    Ritu A Shetty
    Department of Pharmacology and Neuroscience and Institute for Aging and Alzheimer s Disease Research, University of North Texas Health Science Center at Fort Worth, 3500 Camp Bowie, Fort Worth, TX, 76107, USA
    Age (Dordr) 35:1821-34. 2013
  5. pmc Dissociation of functional status from accrual of CML and RAGE in the aged mouse brain
    Nopporn Thangthaeng
    Department of Pharmacology and Neuroscience, University of North Texas Health Science Center, 3500 Camp Bowie Boulevard, Fort Worth, TX 76107, USA
    Exp Gerontol 43:1077-85. 2008
  6. ncbi request reprint Short-term vitamin E intake fails to improve cognitive or psychomotor performance of aged mice
    Nathalie Sumien
    Department of Pharmacology and Neuroscience, Institute for Aging and Alzheimer s Disease Research, University of North Texas Health Science Center at Fort Worth, Fort Worth, TX 76107, USA
    Free Radic Biol Med 36:1424-33. 2004
  7. pmc Coenzyme Q10 and α-tocopherol reversed age-associated functional impairments in mice
    Ritu A Shetty
    Department of Pharmacology and Neuroscience, University of North Texas Health Science Center at Fort Worth, Fort Worth, TX 76107, USA Institute for Aging and Alzheimer s Disease Research, University of North Texas Health Science Center at Fort Worth, Fort Worth, TX 76107, USA
    Exp Gerontol 58:208-18. 2014
  8. pmc Nongradient blue native gel analysis of serum proteins and in-gel detection of serum esterase activities
    Nopporn Thangthaeng
    Department of Pharmacology and Neuroscience, University of North Texas Health Science Center, Fort Worth, TX 76107, USA
    J Chromatogr B Analyt Technol Biomed Life Sci 879:386-94. 2011
  9. pmc Transient focal cerebral ischemia induces long-term cognitive function deficit in an experimental ischemic stroke model
    Wenjun Li
    Department of Pharmacology and Neuroscience, University of North Texas Health Science Center, Fort Worth, TX 76107, USA
    Neurobiol Dis 59:18-25. 2013
  10. pmc Curcumin Mimics the Neurocognitive and Anti-Inflammatory Effects of Caloric Restriction in a Mouse Model of Midlife Obesity
    Marjana Rahman Sarker
    Department of Pharmacology and Neuroscience, Institute for Aging and Alzheimer s Disease Research IAADR, University of North Texas Health Science Center, Fort Worth, Texas, United States of America
    PLoS ONE 10:e0140431. 2015

Collaborators

Detail Information

Publications13

  1. pmc Does phytoestrogen supplementation affect cognition differentially in males and females?
    Nathalie Sumien
    Department of Pharmacology and Neuroscience, UNT Health Science Center at Fort Worth, Institute for Aging and Alzheimer s Disease Research, Fort Worth, TX 76107, USA
    Brain Res 1514:123-7. 2013
    ....
  2. pmc Reversible inactivation of dihydrolipoamide dehydrogenase by mitochondrial hydrogen peroxide
    Liang Jun Yan
    Department of Pharmacology and Neuroscience and Institute for Aging and Alzheimer s Disease Research, University of North Texas Health Science Center, Fort Worth, TX 76107, USA
    Free Radic Res 47:123-33. 2013
    ..Taken together, the present study provides insights into the mechanisms of DLDH oxidative inactivation by mitochondrial H2O2...
  3. pmc Prolonged intake of coenzyme Q10 impairs cognitive functions in mice
    Nathalie Sumien
    Department of Pharmacology and Neuroscience, Institute for Aging and Alzheimer s Disease Research, University of North Texas Health Science Center, Fort Worth, TX 76107, USA
    J Nutr 139:1926-32. 2009
    ..These findings do not support the notion that CoQ(10) is a fitness-enhancing or an "antiaging" substance under normal physiological conditions...
  4. pmc Coenzyme Q(10) supplementation reverses age-related impairments in spatial learning and lowers protein oxidation
    Ritu A Shetty
    Department of Pharmacology and Neuroscience and Institute for Aging and Alzheimer s Disease Research, University of North Texas Health Science Center at Fort Worth, 3500 Camp Bowie, Fort Worth, TX, 76107, USA
    Age (Dordr) 35:1821-34. 2013
    ..Thus, in individuals with age-associated symptoms of cognitive decline, high-CoQ intake may be beneficial...
  5. pmc Dissociation of functional status from accrual of CML and RAGE in the aged mouse brain
    Nopporn Thangthaeng
    Department of Pharmacology and Neuroscience, University of North Texas Health Science Center, 3500 Camp Bowie Boulevard, Fort Worth, TX 76107, USA
    Exp Gerontol 43:1077-85. 2008
    ..The findings from this study suggest that accrual of CML and expression of RAGE in different brain regions are time-related phenomena that do not account for individual differences in brain aging or cognitive decline...
  6. ncbi request reprint Short-term vitamin E intake fails to improve cognitive or psychomotor performance of aged mice
    Nathalie Sumien
    Department of Pharmacology and Neuroscience, Institute for Aging and Alzheimer s Disease Research, University of North Texas Health Science Center at Fort Worth, Fort Worth, TX 76107, USA
    Free Radic Biol Med 36:1424-33. 2004
    ..Moreover, the current findings indicate that vitamin E could have detrimental effects on some brain functions when implemented in older animals...
  7. pmc Coenzyme Q10 and α-tocopherol reversed age-associated functional impairments in mice
    Ritu A Shetty
    Department of Pharmacology and Neuroscience, University of North Texas Health Science Center at Fort Worth, Fort Worth, TX 76107, USA Institute for Aging and Alzheimer s Disease Research, University of North Texas Health Science Center at Fort Worth, Fort Worth, TX 76107, USA
    Exp Gerontol 58:208-18. 2014
    ..Moreover, concurrent supplementation of CoQ10 and Toc may be more effective than either antioxidant alone...
  8. pmc Nongradient blue native gel analysis of serum proteins and in-gel detection of serum esterase activities
    Nopporn Thangthaeng
    Department of Pharmacology and Neuroscience, University of North Texas Health Science Center, Fort Worth, TX 76107, USA
    J Chromatogr B Analyt Technol Biomed Life Sci 879:386-94. 2011
    ..Results of the present study demonstrate that nongradient BN-PAGE can serve as a feasible analytical tool for proteomic and enzymatic analysis of serum proteins...
  9. pmc Transient focal cerebral ischemia induces long-term cognitive function deficit in an experimental ischemic stroke model
    Wenjun Li
    Department of Pharmacology and Neuroscience, University of North Texas Health Science Center, Fort Worth, TX 76107, USA
    Neurobiol Dis 59:18-25. 2013
    ..Our results indicate that the attenuation of GABAergic activity or enhancement of ERK/MAPK activation in the hippocampus might be potential therapeutic approaches to prevent or attenuate cognitive impairment after ischemic stroke. ..
  10. pmc Curcumin Mimics the Neurocognitive and Anti-Inflammatory Effects of Caloric Restriction in a Mouse Model of Midlife Obesity
    Marjana Rahman Sarker
    Department of Pharmacology and Neuroscience, Institute for Aging and Alzheimer s Disease Research IAADR, University of North Texas Health Science Center, Fort Worth, Texas, United States of America
    PLoS ONE 10:e0140431. 2015
    ..The results suggest that, independent of their effects on adiposity; dietary curcumin and caloric restriction have positive effects on frontal cortical functions that could be linked to anti-inflammatory or antioxidant actions. ..
  11. doi request reprint Exercise, but not antioxidants, reversed ApoE4-associated motor impairments in adult GFAP-ApoE mice
    Kiran Chaudhari
    Center for Neuroscience Discovery, Institute for Healthy Aging, University of North Texas Health Science Center at Fort Worth, Fort Worth, TX 76107, USA
    Behav Brain Res 305:37-45. 2016
    ..These data suggest that environmental and genetic factors influence the outcome of interventions on motor function and should be investigated more thoroughly and taken into consideration when implementing changes in lifestyles. ..
  12. pmc The effects of sigma (σ1) receptor-selective ligands on muscarinic receptor antagonist-induced cognitive deficits in mice
    Maninder Malik
    Department of Pharmacology and Neuroscience, University of North Texas Health Science Center, Fort Worth, TX, USA
    Br J Pharmacol 172:2519-31. 2015
    ..Currently available therapeutic drugs provide only symptomatic relief. Therefore, novel therapeutic strategies are needed to retard and/or arrest the progressive loss of memory...
  13. ncbi request reprint Supplementation with vitamin E fails to attenuate oxidative damage in aged mice
    Nathalie Sumien
    Department of Pharmacology and Neuroscience, Institute for Aging and Alzheimer s Disease Research, University of North Texas Health Science Center at Fort Worth, 3500 Camp Bowie Blvd, Fort Worth, TX 76107 2699, USA
    Exp Gerontol 38:699-704. 2003
    ..This difference could explain why alpha-tocopherol administration has been found to be ineffective in the extension of the life span...