Miguel A Serra

Summary

Affiliation: University of Valencia
Country: Spain

Publications

  1. ncbi request reprint Prevalence of hepatitis C virus in patients with lichen planus of the oral cavity and chronic liver disease
    J A del Olmo
    Service of Hepatology, Hospital Clinico Universitario, Valencia, Spain
    Eur J Oral Sci 108:378-82. 2000
  2. ncbi request reprint Effect of hepatitis C virus infection and abstinence from alcohol on survival in patients with alcoholic cirrhosis
    Miguel A Serra
    Service of Hepatology, Hospital Clinico Universitario, Faculty of Medicine, Valencia, Spain
    J Clin Gastroenterol 36:170-4. 2003
  3. ncbi request reprint Clinical value of increased serum creatinine concentration as predictor of short-term outcome in decompensated cirrhosis
    M A Serra
    Service of Hepatology, Hospital Clinico Universitario, University of Valencia, ES 46010 Valencia, Spain
    Scand J Gastroenterol 39:1149-53. 2004
  4. ncbi request reprint [The time factor in the management of chronic hepatitis C]
    M A Serra
    Servicio de Hepatologia, Hospital Clinico Universitario de Valencia, Universitat de Valencia
    Rev Esp Enferm Dig 100:230-5. 2008
  5. ncbi request reprint Influence of age and date of infection on distribution of hepatitis C virus genotypes and fibrosis stage
    M A Serra
    Service of Hepatology, Hospital Clinico Universitario, Facultad de Medicina, Avda Blasco Ibanez 15, E 46010 Valencia, Spain
    J Viral Hepat 10:183-8. 2003
  6. doi request reprint Unchanged plasma levels of dimethylarginines and nitric oxide in chronic hepatitis C
    Paloma Lluch
    Servicio de Hepatologia, Hospital Clinico Universitario, Valencia, Spain
    Scand J Gastroenterol 44:224-8. 2009
  7. doi request reprint Serum nitrotyrosine and psychometric tests as indicators of impaired fitness to drive in cirrhotic patients with minimal hepatic encephalopathy
    Vicente Felipo
    Laboratory of Neurobiology, Centro de Investigacion Principe Felipe, Valencia, Spain
    Liver Int 33:1478-89. 2013
  8. ncbi request reprint Activation of soluble guanylate cyclase by nitric oxide in lymphocytes correlates with minimal hepatic encephalopathy in cirrhotic patients
    Carmina Montoliu
    Servicio de Hepatologia, Departamento de Medicina, Hospital Clinico Universitario, Universidad de Valencia, Valencia, Spain
    J Mol Med (Berl) 85:237-45. 2007
  9. doi request reprint 3-nitro-tyrosine as a peripheral biomarker of minimal hepatic encephalopathy in patients with liver cirrhosis
    Carmina Montoliu
    Fundación Investigación Hospital Clínico Universitario de Valencia, INCLIVA, Valencia, Spain
    Am J Gastroenterol 106:1629-37. 2011
  10. doi request reprint IL-6 and IL-18 in blood may discriminate cirrhotic patients with and without minimal hepatic encephalopathy
    Carmina Montoliu
    Fundación Investigación Hospital Clínico de Valencia, Valencia, Spain
    J Clin Gastroenterol 43:272-9. 2009

Collaborators

Detail Information

Publications24

  1. ncbi request reprint Prevalence of hepatitis C virus in patients with lichen planus of the oral cavity and chronic liver disease
    J A del Olmo
    Service of Hepatology, Hospital Clinico Universitario, Valencia, Spain
    Eur J Oral Sci 108:378-82. 2000
    ..1%). It is concluded that HCV infection plays an etiopathogenetic role in CLD associated with oral LP, whereas according to the present findings, the majority of patients suffering exclusively from oral LP are not infected by the HCV...
  2. ncbi request reprint Effect of hepatitis C virus infection and abstinence from alcohol on survival in patients with alcoholic cirrhosis
    Miguel A Serra
    Service of Hepatology, Hospital Clinico Universitario, Faculty of Medicine, Valencia, Spain
    J Clin Gastroenterol 36:170-4. 2003
    ..We assessed the effect of HCV infection and abstinence from alcohol on survival in a cohort of patients with alcoholic cirrhosis...
  3. ncbi request reprint Clinical value of increased serum creatinine concentration as predictor of short-term outcome in decompensated cirrhosis
    M A Serra
    Service of Hepatology, Hospital Clinico Universitario, University of Valencia, ES 46010 Valencia, Spain
    Scand J Gastroenterol 39:1149-53. 2004
    ..The purpose of this study was to assess whether serum creatinine concentration alone or associated with other biological parameters was an independent predictor of short-term mortality in patients with decompensated cirrhosis...
  4. ncbi request reprint [The time factor in the management of chronic hepatitis C]
    M A Serra
    Servicio de Hepatologia, Hospital Clinico Universitario de Valencia, Universitat de Valencia
    Rev Esp Enferm Dig 100:230-5. 2008
  5. ncbi request reprint Influence of age and date of infection on distribution of hepatitis C virus genotypes and fibrosis stage
    M A Serra
    Service of Hepatology, Hospital Clinico Universitario, Facultad de Medicina, Avda Blasco Ibanez 15, E 46010 Valencia, Spain
    J Viral Hepat 10:183-8. 2003
    ..In summary, spread of intravenous drug use determined HCV infection by genotypes other than 1b. The risk of fibrosis progression was influenced more by age at viral acquisition and alcohol consumption than by the infecting genotype...
  6. doi request reprint Unchanged plasma levels of dimethylarginines and nitric oxide in chronic hepatitis C
    Paloma Lluch
    Servicio de Hepatologia, Hospital Clinico Universitario, Valencia, Spain
    Scand J Gastroenterol 44:224-8. 2009
    ..The objective of this study was to determine whether plasma levels of ADMA, SDMA and NO are altered in patients with chronic hepatitis C...
  7. doi request reprint Serum nitrotyrosine and psychometric tests as indicators of impaired fitness to drive in cirrhotic patients with minimal hepatic encephalopathy
    Vicente Felipo
    Laboratory of Neurobiology, Centro de Investigacion Principe Felipe, Valencia, Spain
    Liver Int 33:1478-89. 2013
    ..The aims of this work were as follows: (i) to shed light on the neurological deficits contributing to impair driving; (ii) to assess whether some psychometric test or biochemical parameter is a good indicator of driving impairment...
  8. ncbi request reprint Activation of soluble guanylate cyclase by nitric oxide in lymphocytes correlates with minimal hepatic encephalopathy in cirrhotic patients
    Carmina Montoliu
    Servicio de Hepatologia, Departamento de Medicina, Hospital Clinico Universitario, Universidad de Valencia, Valencia, Spain
    J Mol Med (Berl) 85:237-45. 2007
    ..This suggests that altered modulation of guanylate cyclase by NO in lymphocytes would reflect a parallel alteration in the brain occurring in patients with MHE that would be involved in their cognitive impairment...
  9. doi request reprint 3-nitro-tyrosine as a peripheral biomarker of minimal hepatic encephalopathy in patients with liver cirrhosis
    Carmina Montoliu
    Fundación Investigación Hospital Clínico Universitario de Valencia, INCLIVA, Valencia, Spain
    Am J Gastroenterol 106:1629-37. 2011
    ..It would be very useful to have some blood biomarker reflecting the presence of MHE in cirrhotic patients. The aim of this work was to identify serum molecules useful as biomarkers for MHE...
  10. doi request reprint IL-6 and IL-18 in blood may discriminate cirrhotic patients with and without minimal hepatic encephalopathy
    Carmina Montoliu
    Fundación Investigación Hospital Clínico de Valencia, Valencia, Spain
    J Clin Gastroenterol 43:272-9. 2009
    ..The aim of the present work was to assess whether there is a correlation between the alterations in parameters reflecting inflammation, hyperammonemia, and the presence of MHE...
  11. ncbi request reprint A single transient episode of hyperammonemia induces long-lasting alterations in protein kinase A
    Carmina Montoliu
    Servicio de Hepatologia, Hospital Clinico Universitario, Departamento de Medicina, Universidad de Valencia, Valencia, Spain
    Am J Physiol Gastrointest Liver Physiol 292:G305-14. 2007
    ..These alterations may contribute to the poor prognosis of patients suffering hepatic encephalopathy...
  12. ncbi request reprint Accumulation of symmetric dimethylarginine in hepatorenal syndrome
    Paloma Lluch
    Servicio de Hepatologia, Hospital Clinico Universitario, Departamento de Medicina, Universidad de Valencia, Valencia, Spain
    Exp Biol Med (Maywood) 231:70-5. 2006
    ..Accumulation of ADMA as a result of impaired hepatic removal may be the causative factor initiating renal vasoconstriction and SDMA retention in the kidney...
  13. ncbi request reprint Correlation of nitric oxide and atrial natriuretic peptide changes with altered cGMP homeostasis in liver cirrhosis
    Carmina Montoliu
    Servicio de Hepatologia, Hospital Clinico Universitario, Departamento de Medicina, Universidad de Valencia, Valencia, Spain
    Liver Int 25:787-95. 2005
    ..Three possible mechanisms may contribute: increased cGMP synthesis by soluble (activated by nitric oxide), or particulate (activated by atrial natriuretic peptide (ANP)) guanylate cyclase or increased release from cells...
  14. doi request reprint Contribution of hyperammonemia and inflammatory factors to cognitive impairment in minimal hepatic encephalopathy
    Vicente Felipo
    Laboratory of Neurobiology Centro de Investigación Príncipe Felipe, Valencia, Spain
    Metab Brain Dis 27:51-8. 2012
    ..Hyperammonemia or inflammation alone did not induce CI but the combination of certain levels of hyperammonemia and inflammation is enough to induce CI, even without liver disease...
  15. doi request reprint Patients with minimal hepatic encephalopathy show impaired mismatch negativity correlating with reduced performance in attention tests
    Vicente Felipo
    Laboratory of Neurobiology, Centro Investigación Príncipe Felipe, Valencia, Spain
    Hepatology 55:530-9. 2012
    ..Receiver operating characteristic curve analyses showed that MMN area predicts attention deficits in the number connection tests A and B, Stroop tasks, and MHE, with sensitivities of 75%-90% and specificities of 76%-83%...
  16. doi request reprint Pegylated alpha-interferon-2a plus ribavirin compared with pegylated alpha-interferon-2b plus ribavirin for initial treatment of chronic hepatitis C virus: prospective, non-randomized study
    Amparo Escudero
    Service of Hepatology, University Hospital Clinic, Department of Medicine, University of Valencia, Valencia, Spain
    J Gastroenterol Hepatol 23:861-6. 2008
    ....
  17. doi request reprint Altered postural control and stability in cirrhotic patients with minimal hepatic encephalopathy correlate with cognitive deficits
    Amparo Urios
    Instituto de Investigación Sanitaria INCLIVA, Valencia, Spain
    Liver Int . 2016
    ..We also assessed if alterations in postural control correlate with neurological impairment and/or blood biomarkers...
  18. ncbi request reprint Risk factors for nonhepatic surgery in patients with cirrhosis
    Juan A Del Olmo
    Service of Hepatology, Hospital Clinico Universitario, Avenida Blasco Ibañez 17, E 46010 Valencia, Spain
    World J Surg 27:647-52. 2003
    ..Independent variables associated with perioperative mortality include preoperative Child-Pugh score, the duration of surgery, and the presence of postoperative general complications...
  19. doi request reprint Serum metabolic signature of minimal hepatic encephalopathy by (1)H-nuclear magnetic resonance
    Beatriz Jimenez
    Structural Biochemistry Laboratory, Centro de Investigacion Principe Felipe, Valencia, Spain
    J Proteome Res 9:5180-7. 2010
    ....
  20. ncbi request reprint Changing prevalence, clinical features, and outcome of acute hepatitis in Spain (1982-2003)
    Juan A Del Olmo
    Service of Hepatology, University Clinic Hospital, Department of Medicine, University of Valencia, Avda Blasco Ibanez 17, E 46010 Valencia, Spain
    J Gastroenterol Hepatol 21:982-7. 2006
    ..Diagnostic and preventive measures have contributed to a change in the epidemiology of acute hepatitis. The purpose of the present paper was to assess the changing prevalence of acute hepatitis from 1982 to 2003...
  21. ncbi request reprint Increased protein kinase A regulatory subunit content and cGMP binding in erythrocyte membranes in liver cirrhosis
    Carmina Montoliu
    Servicio de Hepatologia, Hospital Clinico Universitario, Departamento de Medicina, Universidad de Valencia, Valencia, Spain
    J Hepatol 40:766-73. 2004
    ..The results obtained led to a new aim: to identify and quantify a protein responsible for the increased cGMP binding found in erythrocyte membranes from patients with liver disease...
  22. ncbi request reprint Plasma concentrations of nitric oxide and asymmetric dimethylarginine in human alcoholic cirrhosis
    Paloma Lluch
    Servicio de Hepatologia, Hospital Clinico Universitario, Departamento de Medicina, Universidad de Valencia, Blasco Ibanez 17, 46010 Valencia, Spain
    J Hepatol 41:55-9. 2004
    ..This study was designed to determine whether plasma levels of ADMA and NO production are altered in patients with compensated and decompensated alcoholic cirrhosis...
  23. ncbi request reprint Altered modulation of soluble guanylate cyclase by nitric oxide in patients with liver disease
    R Corbalan
    Laboratory of Neurobiology, Instituto de Investigaciones Citologicas, FVIB, Valencia, Spain
    Metab Brain Dis 17:295-301. 2002
    ..Altered modulation of soluble guanylate cyclase by NO in liver disease may play a role in the neurological and hemodynamic alterations in these patients...
  24. ncbi request reprint Alterations in soluble guanylate cyclase content and modulation by nitric oxide in liver disease
    Regina Rodrigo
    Laboratory of Neurobiology, Fundacion Valenciana de Investigaciones Biomedicas, Amadeo de Saboya 4, 46010 Valencia, Spain
    Neurochem Int 45:947-53. 2004
    ..These alterations could be responsible for some of the neurological alterations in hepatic encephalopathy such as sleep disturbances and cognitive impairment...