Eva E Rufino-Palomares

Summary

Affiliation: University of Granada
Country: Spain

Publications

  1. doi request reprint NADPH production, a growth marker, is stimulated by maslinic acid in gilthead sea bream by increased NADP-IDH and ME expression
    Eva E Rufino-Palomares
    Department of Biochemistry and Molecular Biology I, Faculty of Sciences, University of Granada, Granada, Spain Electronic address
    Comp Biochem Physiol C Toxicol Pharmacol 187:32-42. 2016
  2. pmc The natural triterpene maslinic acid induces apoptosis in HT29 colon cancer cells by a JNK-p53-dependent mechanism
    Fernando J Reyes-Zurita
    Department of Biochemistry and Molecular Biology I, University of Granada, 18071 Granada, Spain
    BMC Cancer 11:154. 2011
  3. doi request reprint Antitumour activity on extrinsic apoptotic targets of the triterpenoid maslinic acid in p53-deficient Caco-2 adenocarcinoma cells
    Fernando J Reyes-Zurita
    Department of Biochemistry and Molecular Biology I, University of Granada, 18071 Granada, Spain Electronic address
    Biochimie 95:2157-67. 2013
  4. doi request reprint Maslinic acid, a triterpenic anti-tumoural agent, interferes with cytoskeleton protein expression in HT29 human colon-cancer cells
    Eva E Rufino-Palomares
    Department of Biochemistry and Molecular Biology I, Faculty of Sciences, University of Granada, Campus Fuentenueva, 18001 Granada, Spain
    J Proteomics 83:15-25. 2013
  5. doi request reprint Target molecules in 3T3-L1 adipocytes differentiation are regulated by maslinic acid, a natural triterpene from Olea europaea
    Amalia Pérez-Jiménez
    Department of Biochemistry and Molecular Biology I, Faculty of Sciences, University of Granada, 18071 Granada, Spain Department of i D I, Biomaslinic S L, Polígono Industrial de Escúzar, 18130 Granada, Spain Electronic address
    Phytomedicine 23:1301-1311. 2016
  6. pmc Maslinic Acid, a Natural Triterpene, Induces a Death Receptor-Mediated Apoptotic Mechanism in Caco-2 p53-Deficient Colon Adenocarcinoma Cells
    Fernando J Reyes-Zurita
    Department of Biochemistry and Molecular Biology I, Faculty of Sciences, University of Granada, 18071, Granada, Spain
    PLoS ONE 11:e0146178. 2016
  7. pmc Maslinic Acid, a Triterpene from Olive, Affects the Antioxidant and Mitochondrial Status of B16F10 Melanoma Cells Grown under Stressful Conditions
    Khalida Mokhtari
    Department of Biochemistry and Molecular Biology I, Faculty of Sciences, University of Granada, 18071 Granada, Spain Department of Microbiology, Faculty of Sciences, Mohammed I University of Oujda, 60000 Oujda, Morocco
    Evid Based Complement Alternat Med 2015:272457. 2015
  8. doi request reprint Maslinic acid, a natural triterpene from Olea europaea L., induces apoptosis in HT29 human colon-cancer cells via the mitochondrial apoptotic pathway
    Fernando J Reyes-Zurita
    Department of Biochemistry and Molecular Biology I, Faculty of Sciences, University of Granada, Campus Fuentenueva s n, 18071 Granada, Spain
    Cancer Lett 273:44-54. 2009
  9. pmc Expression inactivation of SMARCA4 by microRNAs in lung tumors
    Isabel F Coira
    Department of Biochemistry and Molecular Biology, University of Granada, Granada, Spain, Centre for Genomics and Oncological Research GENYO, Granada, Spain
    Hum Mol Genet 24:1400-9. 2015

Collaborators

  • Fernando J Reyes-Zurita
  • Andres Parra
  • Gisela Pachón-Peña
  • Amalia Pérez-Jiménez
  • Khalida Mokhtari
  • Pedro P Medina
  • Juan Peragón
  • José A Lupiáñez
  • Leticia García-Salguero
  • Isabel F Coira
  • M Carmen Ortuño-Costela
  • Nieves Fernández-Gallego
  • Celeny Figuera
  • Octavio A Romero
  • Jos A Lupiáñez
  • Julian Carretero
  • Montse Sanchez-Cespedes
  • Esther Farez-Vidal
  • Marta Cuadros
  • Chanatip Metheetrairut
  • Laura Boyero-Corral
  • Frank J Slack
  • Paola Peinado

Detail Information

Publications9

  1. doi request reprint NADPH production, a growth marker, is stimulated by maslinic acid in gilthead sea bream by increased NADP-IDH and ME expression
    Eva E Rufino-Palomares
    Department of Biochemistry and Molecular Biology I, Faculty of Sciences, University of Granada, Granada, Spain Electronic address
    Comp Biochem Physiol C Toxicol Pharmacol 187:32-42. 2016
    ....
  2. pmc The natural triterpene maslinic acid induces apoptosis in HT29 colon cancer cells by a JNK-p53-dependent mechanism
    Fernando J Reyes-Zurita
    Department of Biochemistry and Molecular Biology I, University of Granada, 18071 Granada, Spain
    BMC Cancer 11:154. 2011
    ..In our latest work we have investigated further this compound's apoptotic molecular mechanism...
  3. doi request reprint Antitumour activity on extrinsic apoptotic targets of the triterpenoid maslinic acid in p53-deficient Caco-2 adenocarcinoma cells
    Fernando J Reyes-Zurita
    Department of Biochemistry and Molecular Biology I, University of Granada, 18071 Granada, Spain Electronic address
    Biochimie 95:2157-67. 2013
    ..Natural agents able to activate both the extrinsic and intrinsic apoptotic pathways by avoiding the mitochondrial resistance mechanisms may be useful for treatment against colon cancer regardless of its aetiology...
  4. doi request reprint Maslinic acid, a triterpenic anti-tumoural agent, interferes with cytoskeleton protein expression in HT29 human colon-cancer cells
    Eva E Rufino-Palomares
    Department of Biochemistry and Molecular Biology I, Faculty of Sciences, University of Granada, Campus Fuentenueva, 18001 Granada, Spain
    J Proteomics 83:15-25. 2013
    ..This is the first evidence obtained of the regulatory effects of MA on the cytoskeleton, which may prove to be one of the bases of its anti-proliferative effect against colon-cancer cells...
  5. doi request reprint Target molecules in 3T3-L1 adipocytes differentiation are regulated by maslinic acid, a natural triterpene from Olea europaea
    Amalia Pérez-Jiménez
    Department of Biochemistry and Molecular Biology I, Faculty of Sciences, University of Granada, 18071 Granada, Spain Department of i D I, Biomaslinic S L, Polígono Industrial de Escúzar, 18130 Granada, Spain Electronic address
    Phytomedicine 23:1301-1311. 2016
    ..Maslinic acid (MA) is a natural product with demonstrated pharmacological functions including anti-inflammation, anti-tumor and anti-oxidation, among others...
  6. pmc Maslinic Acid, a Natural Triterpene, Induces a Death Receptor-Mediated Apoptotic Mechanism in Caco-2 p53-Deficient Colon Adenocarcinoma Cells
    Fernando J Reyes-Zurita
    Department of Biochemistry and Molecular Biology I, Faculty of Sciences, University of Granada, 18071, Granada, Spain
    PLoS ONE 11:e0146178. 2016
    ..Natural antitumoral agents capable of activating both the extrinsic and intrinsic apoptotic pathways could be of great use in treating colon-cancer of whatever origin. ..
  7. pmc Maslinic Acid, a Triterpene from Olive, Affects the Antioxidant and Mitochondrial Status of B16F10 Melanoma Cells Grown under Stressful Conditions
    Khalida Mokhtari
    Department of Biochemistry and Molecular Biology I, Faculty of Sciences, University of Granada, 18071 Granada, Spain Department of Microbiology, Faculty of Sciences, Mohammed I University of Oujda, 60000 Oujda, Morocco
    Evid Based Complement Alternat Med 2015:272457. 2015
    ..Furthermore, MA had an antioxidant effect at lower assayed levels measured as DHR and antioxidant defense. However, at higher dosages MA induced cellular damage by apoptosis as seen in the results obtained...
  8. doi request reprint Maslinic acid, a natural triterpene from Olea europaea L., induces apoptosis in HT29 human colon-cancer cells via the mitochondrial apoptotic pathway
    Fernando J Reyes-Zurita
    Department of Biochemistry and Molecular Biology I, Faculty of Sciences, University of Granada, Campus Fuentenueva s n, 18071 Granada, Spain
    Cancer Lett 273:44-54. 2009
    ..Our results suggest that maslinic acid has the potential to provide significant natural defence against colon-cancer...
  9. pmc Expression inactivation of SMARCA4 by microRNAs in lung tumors
    Isabel F Coira
    Department of Biochemistry and Molecular Biology, University of Granada, Granada, Spain, Centre for Genomics and Oncological Research GENYO, Granada, Spain
    Hum Mol Genet 24:1400-9. 2015
    ..In addition, these results could lead to application of incipient miRNA technology to the aforementioned synthetic lethal therapeutic strategies. ..