P Molina

Summary

Affiliation: University of Murcia
Country: Spain

Publications

  1. ncbi request reprint Carbodiimide-mediated preparation of the tricyclic pyrido[3',2':4,5]pyrrolo[1,2-c]pyrimidine ring system and its application to the synthesis of the potent antitumoral marine alkaloid variolin B and analog
    Pedro Molina
    Departamento de Quimica Organica, Facultad de Quimica, Universidad de Murcia, Campus de Espinardo, Spain
    J Org Chem 68:489-99. 2003
  2. ncbi request reprint Aldimines generated from aza-Wittig reaction between bis(iminophosphoranes) derived from 1,1'-diazidoferrocene and aromatic or heteroaromatic aldehydes: electrochemical and optical behaviour towards metal cations
    Antonia Sola
    Departamento de Quimica Organica, Universidad de Murcia, Campus de Espinardo, 30100, Murcia, Spain
    Dalton Trans 40:12548-59. 2011
  3. ncbi request reprint Preparation and sensing properties of a nitrogen-rich ferrocene-imidazole-quinoxaline triad decorated with pyrrole rings
    María Alfonso
    Departamento de Quimica Organica, Universidad de Murcia, Campus de Espinardo, E 30100 Murcia, Spain
    Dalton Trans 45:19269-19276. 2016
  4. ncbi request reprint Synthesis and properties of a new class of nitrogen-rich multinuclear[m.n] ferrocenophanes
    Alberto Tarraga
    Departamento de Quimica Organica, Facultad de Quimica, Universidad de Murcia, Murcia, Spain
    Chem Commun (Camb) . 2004
  5. pmc Multifunctional Benzothiadiazole-Based Small Molecules Displaying Solvatochromism and Sensing Properties toward Nitroarenes, Anions, and Cations
    María Alfonso
    Departamento de Quimica Organica, Universidad de Murcia Campus de Espinardo, 30100 Murcia Spain E mail
    ChemistryOpen 3:242-9. 2014
  6. doi request reprint Tris(triazole) tripodal receptors as selective probes for citrate anion recognition and multichannel transition and heavy metal cation sensing
    Maria Del Carmen Gonzalez
    Departamento de Quimica Organica, Universidad de Murcia, Campus de Espinardo, 30100, Murcia, Spain
    Org Biomol Chem 13:1429-38. 2015
  7. doi request reprint Discovery of anion-π interactions in the recognition mechanism of inorganic anions by 1,2,3-triazolium rings
    Antonio Caballero
    Departamento de Quimica Organica, Universidad de Murcia, Campus de Espinardo, 30100, Murcia, Spain
    Chem Commun (Camb) 50:4680-2. 2014
  8. doi request reprint The ferrocene-pyrylium dyad as a selective colorimetric chemodosimeter for the toxic cyanide and hydrogen sulfide anions in water
    Antonia Sola
    Departamento de Quimica Organica, Universidad de Murcia, Campus de Espinardo, 30100 Murcia, Spain
    Org Biomol Chem 12:2547-51. 2014
  9. doi request reprint A densely decorated disubstituted ferrocene as an ion-pair recognition receptor
    Maria Del Carmen Gonzalez
    Departamento de Quimica Organica, Universidad de Murcia, Campus de Espinardo, 30100, Murcia, Spain
    Chem Commun (Camb) 49:9633-5. 2013
  10. doi request reprint Ferrocene-based multichannel ion-pair recognition receptors
    Pedro Molina
    Departamento de Quimica Organica, Universidad de Murcia, Campus de Espinardo, 30100 Murcia, Spain
    Dalton Trans 43:18-29. 2014

Collaborators

  • Ibon Alkorta
  • Janet E Del Bene
  • David Curiel
  • M J Alcaraz
  • Pilar M Fresneda
  • Alberto Tarraga
  • Arturo Espinosa
  • María Alfonso
  • Antonia Sola
  • Antonio Caballero
  • Francisco Otón
  • Maria Del Carmen Gonzalez
  • Fabiola Zapata
  • Guzmán Sánchez
  • Jaume Veciana
  • David J Evans
  • M Desamparados Velasco
  • Juan Luis Lopez
  • Jose Elguero
  • Lidia González
  • Imma Ratera
  • Julia Contreras-García
  • K Wurst
  • Concepció Rovira
  • José Vidal-Gancedo
  • Vega Lloveras

Detail Information

Publications23

  1. ncbi request reprint Carbodiimide-mediated preparation of the tricyclic pyrido[3',2':4,5]pyrrolo[1,2-c]pyrimidine ring system and its application to the synthesis of the potent antitumoral marine alkaloid variolin B and analog
    Pedro Molina
    Departamento de Quimica Organica, Facultad de Quimica, Universidad de Murcia, Campus de Espinardo, Spain
    J Org Chem 68:489-99. 2003
    ..Ultimate, thermal decarboxylation with concomitant O-methyl deprotection and further N-benzyl deprotection by the action of triflic acid completed the synthesis of the target natural product variolin B...
  2. ncbi request reprint Aldimines generated from aza-Wittig reaction between bis(iminophosphoranes) derived from 1,1'-diazidoferrocene and aromatic or heteroaromatic aldehydes: electrochemical and optical behaviour towards metal cations
    Antonia Sola
    Departamento de Quimica Organica, Universidad de Murcia, Campus de Espinardo, 30100, Murcia, Spain
    Dalton Trans 40:12548-59. 2011
    ..From the (1)H NMR titration data as well as DFT calculations, different tentative binding modes have been established, for these structurally related ferrocenyl derivatives...
  3. ncbi request reprint Preparation and sensing properties of a nitrogen-rich ferrocene-imidazole-quinoxaline triad decorated with pyrrole rings
    María Alfonso
    Departamento de Quimica Organica, Universidad de Murcia, Campus de Espinardo, E 30100 Murcia, Spain
    Dalton Trans 45:19269-19276. 2016
    ..Thus, this receptor shows an important enhancement for binding AcO- anions when it is co-bound to Hg2+cations, whereas no affinity for the free receptor by the anion is observed...
  4. ncbi request reprint Synthesis and properties of a new class of nitrogen-rich multinuclear[m.n] ferrocenophanes
    Alberto Tarraga
    Departamento de Quimica Organica, Facultad de Quimica, Universidad de Murcia, Murcia, Spain
    Chem Commun (Camb) . 2004
    ..The electronic behaviour of these multinuclear ferrocenophanes indicates a strong electronic coupling between the iron centers...
  5. pmc Multifunctional Benzothiadiazole-Based Small Molecules Displaying Solvatochromism and Sensing Properties toward Nitroarenes, Anions, and Cations
    María Alfonso
    Departamento de Quimica Organica, Universidad de Murcia Campus de Espinardo, 30100 Murcia Spain E mail
    ChemistryOpen 3:242-9. 2014
    ..Specifically, the two sensors were shown to discriminate between p-nitrophenol and picric acid. Finally, the mechanism of fluorescence quenching upon addition of nitrophenols was determined by computational methods. ..
  6. doi request reprint Tris(triazole) tripodal receptors as selective probes for citrate anion recognition and multichannel transition and heavy metal cation sensing
    Maria Del Carmen Gonzalez
    Departamento de Quimica Organica, Universidad de Murcia, Campus de Espinardo, 30100, Murcia, Spain
    Org Biomol Chem 13:1429-38. 2015
    ..The related three-armed ferrocenyl-triazole receptor 2 behaves as a highly selective dual (redox and chromogenic) chemosensor molecule for Pb(2+) metal cations...
  7. doi request reprint Discovery of anion-π interactions in the recognition mechanism of inorganic anions by 1,2,3-triazolium rings
    Antonio Caballero
    Departamento de Quimica Organica, Universidad de Murcia, Campus de Espinardo, 30100, Murcia, Spain
    Chem Commun (Camb) 50:4680-2. 2014
    ..The simultaneous presence of two noncovalent interactions allows us to achieve a highly selective binding of the hydrogenpyrophosphate anion. ..
  8. doi request reprint The ferrocene-pyrylium dyad as a selective colorimetric chemodosimeter for the toxic cyanide and hydrogen sulfide anions in water
    Antonia Sola
    Departamento de Quimica Organica, Universidad de Murcia, Campus de Espinardo, 30100 Murcia, Spain
    Org Biomol Chem 12:2547-51. 2014
    ....
  9. doi request reprint A densely decorated disubstituted ferrocene as an ion-pair recognition receptor
    Maria Del Carmen Gonzalez
    Departamento de Quimica Organica, Universidad de Murcia, Campus de Espinardo, 30100, Murcia, Spain
    Chem Commun (Camb) 49:9633-5. 2013
    ....
  10. doi request reprint Ferrocene-based multichannel ion-pair recognition receptors
    Pedro Molina
    Departamento de Quimica Organica, Universidad de Murcia, Campus de Espinardo, 30100 Murcia, Spain
    Dalton Trans 43:18-29. 2014
    ..Ferrocenylimidazoles and unsymmetrically 1,1'-disubstituted ferrocenes, bearing a triazole ring directly linked to the redox unit, behave as efficient ion-pair recognition receptors. ..
  11. doi request reprint Modified mesoporous silica nanoparticles as a reusable, selective chromogenic sensor for mercury(II) recognition
    Guzmán Sánchez
    Department of Organic Chemistry, Faculty of Chemistry, University of Murcia, Campus of Espinardo, Murcia, Spain
    Dalton Trans 42:6318-26. 2013
    ..The presence of thioureas conjugated with azobenzene chromophores enables the selective colorimetric detection of mercury(II) cations in THF through a remarkable colour change from yellow to deep purple...
  12. doi request reprint A ferrocenyl-guanidine derivative as a highly selective electrochemical and colorimetric chemosensor molecule for acetate anions
    Antonia Sola
    Departamento de Quimica Organica, Universidad de Murcia, Campus de Espinardo, 30100 Murcia, Spain
    Dalton Trans 41:8401-9. 2012
    ..Its monoprotonated form is able to selectively sense the less basic Cl(-), Br(-), NO(3)(-), and HSO(4)(-) anions: the oxidation redox peak at E(p) = 865 mV is cathodically shifted (107-182 mV)...
  13. ncbi request reprint Multichannel HSO4- recognition promoted by a bound cation within a ferrocene-based ion pair receptor
    María Alfonso
    Departamento de Quimica Organica, Universidad de Murcia, Campus de Espinardo, 30100, Murcia, Spain
    Chem Commun (Camb) 48:6848-50. 2012
    ....
  14. doi request reprint Highly selective mercury(II) cations detection in mixed-aqueous media by a ferrocene-based fluorescent receptor
    María Alfonso
    Departamento de Quimica Organica, Universidad de Murcia, Campus de Espinardo, 30100 Murcia, Spain
    Dalton Trans 41:4437-44. 2012
    ..054) resulted in a 18-fold increase. The combined (1)H NMR data of the complex and the theoretical calculations suggest the proposed bridging coordination mode...
  15. doi request reprint Imidazole derivatives: a comprehensive survey of their recognition properties
    Pedro Molina
    Departamento de Quimica Organica, Universidad de Murcia, Campus de Espinardo, 30100 Murcia, Spain
    Org Biomol Chem 10:1711-24. 2012
    ..As a result, the design of new multichannel imidazole-based receptors capable of recognizing different types of analytes is strongly demanded. This review summarizes the most recent and relevant advances in this area...
  16. ncbi request reprint Inhibition of leukocyte functions by the alkaloid isaindigotone from Isatis indigotica and some new synthetic derivatives
    P Molina
    Departamento de Quimica Organica, Facultad de Quimica, Universidad de Murcia, Murcia, Spain
    J Nat Prod 64:1297-300. 2001
    ..Thus, this series of compounds can attenuate the production of mediators relevant to the inflammatory response...
  17. ncbi request reprint Solid-phase synthesis and inhibitory effects of some pyrido[1,2-c]pyrimidine derivatives on leukocyte formations and experimental inflammation
    P Molina
    Departamento de Quimica Organica, Universidad de Murcia, Murcia E 30071, Spain
    J Med Chem 44:1011-4. 2001
    ..Inhibition of PGE(2) production and superoxide scavenging may participate in the mechanism of the antiinflammatory action of these pyrido[1,2-c]pyrimidine derivatives...
  18. ncbi request reprint Synthesis and cytotoxic evaluation of new derivatives of the marine alkaloid variolin B
    Pilar M Fresneda
    Departamento de Quimica Organica, Facultad de Quimica, Universidad de Murcia, Campus de Espinardo, 30100 Murcia, Spain
    J Med Chem 49:1217-21. 2006
    ..The marine alkaloid variolin B 2 and eight synthetic derivatives with different substituents at positions C-5 and C-7 have been tested in a panel of sixteen human tumor cell lines to evaluate their cytotoxic potential...
  19. ncbi request reprint A simple but effective ferrocene derivative as a redox, colorimetric, and fluorescent receptor for highly selective recognition of Zn2+ ions
    Fabiola Zapata
    Departamento de Quimica Organica, Facultad de Quimica, Universidad de Murcia, Campus de Espinardo, E 30100, Murcia, Spain
    Org Lett 9:2385-8. 2007
    ....
  20. ncbi request reprint Triple channel sensing of Pb(II) ions by a simple multiresponsive ferrocene receptor having a 1-deazapurine backbone
    Fabiola Zapata
    Departamento de Quimica Organica, Facultad de Quimica, Universidad de Murcia, Campus de Espinardo, E 30100 Murcia, Spain
    Org Lett 10:41-4. 2008
    ..7 microg L-1. The signal transduction occurs via a reversible CHEF with this inherent quenching metal ion...
  21. ncbi request reprint A new multifunctional ferrocenyl-substituted ferrocenophane derivative: optical and electronic properties and selective recognition of Mg2+ ions
    Juan Luis Lopez
    Universidad de Murcia, Departamento de Quimica Organica, Facultad de Quimica, Campus de Espinardo, 30100 Murcia, Spain
    Chemistry 10:1815-26. 2004
    ..This mixed-valence species shows a fast intramolecular electron-transfer process, as ascertained by several spectroscopic techniques...
  22. doi request reprint Ferrocene-based small molecules for dual-channel sensing of heavy- and transition-metal cations
    Antonio Caballero
    Departamento de Quimica Organica, Facultad de Quimica, Universidad de Murcia, Campus de Espinardo, E 30100 Murcia, Spain
    J Org Chem 73:5489-97. 2008
    ..The experimental data and conclusions about the ion-sensing properties are supported by DFT calculations...
  23. ncbi request reprint A bis-guanidine-based multisignaling sensor molecule that displays redox-ratiometric behavior or fluorescence enhancement in the presence of anions and cations
    Francisco Otón
    Departamento de Quimica Organica, Universidad de Murcia, Campus de Espinardo, Spain
    Org Lett 8:2107-10. 2006
    ..Sensing of anions (Cl(-), F(-), NO(3)(-), HSO(4)(-), and H(2)PO(4)(-)) takes place by redox-ratiometric measurements, whereas metal ion (Zn(2+), Ni(2+), and Cd(2+)) recognition is achieved by fluorescence measurements...