Patricia Fernandez-Robredo

Summary

Affiliation: University of Navarra
Country: Spain

Publications

  1. pmc Azithromycin reduces inflammation in a rat model of acute conjunctivitis
    Patricia Fernandez-Robredo
    Experimental Ophthalmology Laboratory, Universidad de Navarra, Pamplona Navarra, Spain
    Mol Vis 19:153-65. 2013
  2. pmc Modifying Choroidal Neovascularization Development with a Nutritional Supplement in Mice
    Alina Adriana Ivanescu
    Experimental Ophthalmology Laboratory, School of Medicine, University of Navarra, Irunlarrea s n Street, Los Castaños Building 31008 Pamplona, Spain
    Nutrients 7:5423-42. 2015
  3. doi request reprint Single- and repeated-dose toxicity study of bevacizumab, ranibizumab, and aflibercept in ARPE-19 cells under normal and oxidative stress conditions
    Manuel Saenz-de-Viteri
    Experimental Ophthalmology Laboratory, School of Medicine, University of Navarra, 1 Irunlarrea Street, 31008 Pamplona, Spain Department of Ophthalmology, Clinica Universidad de Navarra, School of Medicine, University of Navarra, 36 Pio XII Avenue, 31008 Pamplona, Spain
    Biochem Pharmacol 103:129-39. 2016
  4. pmc Transforming growth factor-beta inhibition reduces progression of early choroidal neovascularization lesions in rats: P17 and P144 peptides
    Javier Zarranz-Ventura
    Experimental Ophthalmology Laboratory, Universidad de Navarra, Pamplona, Spain
    PLoS ONE 8:e65434. 2013
  5. pmc Evaluation of 10 AMD Associated Polymorphisms as a Cause of Choroidal Neovascularization in Highly Myopic Eyes
    Alvaro Velázquez-Villoria
    Ophthalmology Experimental Laboratory, Universidad de Navarra, Pamplona, Spain
    PLoS ONE 11:e0162296. 2016
  6. pmc Oxidative stress and histological changes in a model of retinal phototoxicity in rabbits
    Manuel Saenz-de-Viteri
    Experimental Ophthalmology Laboratory, School of Medicine, University of Navarra, 1 Irunlarrea Street, 31008 Pamplona, Spain Department of Ophthalmology, Clinica Universidad de Navarra, School of Medicine, University of Navarra, 36 Pio XII Avenue, 31008 Pamplona, Spain
    Oxid Med Cell Longev 2014:637137. 2014
  7. pmc Effect of lutein and antioxidant supplementation on VEGF expression, MMP-2 activity, and ultrastructural alterations in apolipoprotein E-deficient mouse
    Patricia Fernandez-Robredo
    Experimental Ophthalmology Laboratory, Clinica Universidad de Navarra, School of Medicine, University of Navarra, ES 31008 Pamplona, Spain
    Oxid Med Cell Longev 2013:213505. 2013

Collaborators

  • Alfredo Garcia-Layana
  • Javier Dotor
  • Sergio Recalde
  • Manuel Saenz-de-Viteri
  • Alvaro Velázquez-Villoria
  • Jaione Bezunartea
  • Laura García-García
  • NICHOLAS REITER
  • Alina Adriana Ivanescu
  • Maria Hernandez
  • Henar Heras-Mulero
  • Maite Moreno-Orduña
  • Javier Zarranz-Ventura
  • José María Ruiz-Moreno
  • Jaouad Anter
  • Elena Alonso
  • Javier Araiz-Iribarren
  • María Hernández-Sánchez
  • Luis Manuel Sádaba-Echarri
  • Vanessa Fernández-García
  • Aitor Redondo-Exposito
  • Angel Salinas-Alaman
  • Francisco Borras-Cuesta

Detail Information

Publications7

  1. pmc Azithromycin reduces inflammation in a rat model of acute conjunctivitis
    Patricia Fernandez-Robredo
    Experimental Ophthalmology Laboratory, Universidad de Navarra, Pamplona Navarra, Spain
    Mol Vis 19:153-65. 2013
    ..The effect of azithromycin on inflammatory molecules in the lipopolysaccharide-induced rat conjunctivitis model was investigated...
  2. pmc Modifying Choroidal Neovascularization Development with a Nutritional Supplement in Mice
    Alina Adriana Ivanescu
    Experimental Ophthalmology Laboratory, School of Medicine, University of Navarra, Irunlarrea s n Street, Los Castaños Building 31008 Pamplona, Spain
    Nutrients 7:5423-42. 2015
    ..Levels of MMP-2 and NLRP3 were not significantly different between groups. Nutritional supplements either alone or combined with anti-VEGF may mitigate CNV development and inhibit retinal disease involving VEGF overexpression and CNV. ..
  3. doi request reprint Single- and repeated-dose toxicity study of bevacizumab, ranibizumab, and aflibercept in ARPE-19 cells under normal and oxidative stress conditions
    Manuel Saenz-de-Viteri
    Experimental Ophthalmology Laboratory, School of Medicine, University of Navarra, 1 Irunlarrea Street, 31008 Pamplona, Spain Department of Ophthalmology, Clinica Universidad de Navarra, School of Medicine, University of Navarra, 36 Pio XII Avenue, 31008 Pamplona, Spain
    Biochem Pharmacol 103:129-39. 2016
    ..Intracellular accumulation of the drugs does not seem to be toxic or affect cell functions. Our study suggests that anti-VEGFs could have a preventive effect on the maintenance of the RPE barrier under oxidative stress...
  4. pmc Transforming growth factor-beta inhibition reduces progression of early choroidal neovascularization lesions in rats: P17 and P144 peptides
    Javier Zarranz-Ventura
    Experimental Ophthalmology Laboratory, Universidad de Navarra, Pamplona, Spain
    PLoS ONE 8:e65434. 2013
    ..Its potential role in the treatment of early CNV appears promising as a single therapy or adjuvant to anti-VEGF drugs...
  5. pmc Evaluation of 10 AMD Associated Polymorphisms as a Cause of Choroidal Neovascularization in Highly Myopic Eyes
    Alvaro Velázquez-Villoria
    Ophthalmology Experimental Laboratory, Universidad de Navarra, Pamplona, Spain
    PLoS ONE 11:e0162296. 2016
    ..Furthermore we conducted a meta-analysis of COL8A1, CFI and LIPC genes SNPs (rs669676, rs10033900 and rs10468017) and found that only rs669676 of these SNPs were associated with high myopia neovascularization. ..
  6. pmc Oxidative stress and histological changes in a model of retinal phototoxicity in rabbits
    Manuel Saenz-de-Viteri
    Experimental Ophthalmology Laboratory, School of Medicine, University of Navarra, 1 Irunlarrea Street, 31008 Pamplona, Spain Department of Ophthalmology, Clinica Universidad de Navarra, School of Medicine, University of Navarra, 36 Pio XII Avenue, 31008 Pamplona, Spain
    Oxid Med Cell Longev 2014:637137. 2014
    ..This model may be useful in the future to study the protective effect of antioxidant substances or new intraocular lenses with yellow filters. ..
  7. pmc Effect of lutein and antioxidant supplementation on VEGF expression, MMP-2 activity, and ultrastructural alterations in apolipoprotein E-deficient mouse
    Patricia Fernandez-Robredo
    Experimental Ophthalmology Laboratory, Clinica Universidad de Navarra, School of Medicine, University of Navarra, ES 31008 Pamplona, Spain
    Oxid Med Cell Longev 2013:213505. 2013
    ..Moreover, these changes could be prevented by efficient antioxidant treatments...