X Remesar

Summary

Affiliation: Universitat de Barcelona
Country: Spain

Publications

  1. ncbi request reprint Is leptin an insulin counter-regulatory hormone?
    X Remesar
    Departament de Bioquimica i Biologia Molecular, Facultat de Biologia, Universitat de Barcelona, Spain
    FEBS Lett 402:9-11. 1997
  2. ncbi request reprint Daily oral oleoyl-estrone gavage induces a dose-dependent loss of fat in Wistar rats
    M del Mar Grasa
    , Universitat de Barcelona, Spain
    Obes Res 9:202-9. 2001
  3. ncbi request reprint Strain variability in Zucker rats affects their response to oral oleoyl-estrone
    M Díaz-Silva
    Centre Especial de Recerca en Nutricio i Ciencia dels Aliments, Facultat de Biologia, Universitat de Barcelona, Barcelona, Spain
    Diabetes Nutr Metab 17:315-22. 2004
  4. ncbi request reprint Short-term oral oleoyl-estrone treatment increases plasma cholesterol turnover in the rat
    C Cabot
    Departament de Nutrició i Bromatologia, Facultat de Biologia, Universitat de Barcelona, Barcelona, Spain
    Int J Obes (Lond) 29:534-9. 2005
  5. ncbi request reprint Oral gavage of oleoyl-oestrone has a stronger effect on body weight in male Zucker obese rats than in female
    M M Grasa
    , Facultat de Biologia, Universitat de Barcelona, Barcelona, Spain
    Diabetes Obes Metab 3:203-8. 2001
  6. ncbi request reprint Effect of oral oleoyl-estrone on the energy balance of diabetic rats
    M Díaz-Silva
    Centre Especial de Recerca en Nutricio i Ciencia dels Aliments, Facultat de Biologia, Universitat de Barcelona, Barcelona, Spain
    Horm Metab Res 35:471-8. 2003
  7. ncbi request reprint Effect of food deprivation on rat plasma estrone fatty acid esters
    R Vila
    Departament de Bioqu mica i Biologia Molecular, Facultat de Biologia, Universitat de Barcelona, Spain
    Diabetes Obes Metab 1:353-6. 1999
  8. ncbi request reprint Intestinal handling of an oral oleoyl-estrone gavage by the rat
    M Esteve
    Centre Especial de Recerca en Nutricio i Ciencia dels Aliments, Facultat de Biologia, Universitat de Barcelona, Spain
    Life Sci 69:763-77. 2001
  9. ncbi request reprint Oleoyl-estrone does not have direct estrogenic effects on rats
    C Cabot
    , Facultat de Biologia, Universitat de Barcelona, Spain
    Life Sci 69:749-61. 2001
  10. ncbi request reprint Weight loss with long-term intermittent treatment with oral oleoyl-estrone in lean Zucker male rats
    B García-Peláez
    Department de Nutrició i Bromatologia, Facultat de Biologia, Universitat de Barcelona, Barcelona, Spain
    Horm Metab Res 38:497-500. 2006

Collaborators

  • J A Fernandez-Lopez
  • J Peinado-Onsurbe
  • S Cinti
  • M L Granada
  • M Alemany
  • M M Grasa
  • M Esteve
  • C Cabot
  • B García-Peláez
  • R Vila
  • M Díaz-Silva
  • R M Masanés
  • M Blay
  • M del Mar Grasa
  • P Savall
  • P Yubero
  • I Rafecas
  • A Salas
  • J Lopez-Marti
  • R M Massanés
  • V Tang
  • M T Blay
  • X Formiguera
  • R De Matteis
  • M Foz
  • J Virgili
  • S Gómez-Ollés
  • R Ferrer-Lorente
  • R M Gutierrez
  • J Virgilli
  • C Torregrosa
  • J Julve
  • A Alemany
  • R M Guitiérrez
  • C Adan
  • J Julve-Gil
  • I Casals

Detail Information

Publications29

  1. ncbi request reprint Is leptin an insulin counter-regulatory hormone?
    X Remesar
    Departament de Bioquimica i Biologia Molecular, Facultat de Biologia, Universitat de Barcelona, Spain
    FEBS Lett 402:9-11. 1997
    ....
  2. ncbi request reprint Daily oral oleoyl-estrone gavage induces a dose-dependent loss of fat in Wistar rats
    M del Mar Grasa
    , Universitat de Barcelona, Spain
    Obes Res 9:202-9. 2001
    ..These results agree with the postulated role of oleoyl-estrone as a ponderostat signal...
  3. ncbi request reprint Strain variability in Zucker rats affects their response to oral oleoyl-estrone
    M Díaz-Silva
    Centre Especial de Recerca en Nutricio i Ciencia dels Aliments, Facultat de Biologia, Universitat de Barcelona, Barcelona, Spain
    Diabetes Nutr Metab 17:315-22. 2004
    ..This variability must be taken into account when developing a metabolic or hormonal study in which this model of obesity is used...
  4. ncbi request reprint Short-term oral oleoyl-estrone treatment increases plasma cholesterol turnover in the rat
    C Cabot
    Departament de Nutrició i Bromatologia, Facultat de Biologia, Universitat de Barcelona, Barcelona, Spain
    Int J Obes (Lond) 29:534-9. 2005
    ..Since cholesterol levels are deeply affected by oleoyl-estrone, we investigated here whether short-term treatment affected cholesterol turnover and overall metabolite changes...
  5. ncbi request reprint Oral gavage of oleoyl-oestrone has a stronger effect on body weight in male Zucker obese rats than in female
    M M Grasa
    , Facultat de Biologia, Universitat de Barcelona, Barcelona, Spain
    Diabetes Obes Metab 3:203-8. 2001
    ..The results suggest that oleoyl-oestrone, in addition to its slimming effects may be effective as an antidiabetic agent in type 2 diabetes...
  6. ncbi request reprint Effect of oral oleoyl-estrone on the energy balance of diabetic rats
    M Díaz-Silva
    Centre Especial de Recerca en Nutricio i Ciencia dels Aliments, Facultat de Biologia, Universitat de Barcelona, Barcelona, Spain
    Horm Metab Res 35:471-8. 2003
    ..Lack of insulin thus results in limited OE effects, and insulin resistance does not prevent or limit the effects of OE on energy homeostasis or the mobilisation of fat...
  7. ncbi request reprint Effect of food deprivation on rat plasma estrone fatty acid esters
    R Vila
    Departament de Bioqu mica i Biologia Molecular, Facultat de Biologia, Universitat de Barcelona, Spain
    Diabetes Obes Metab 1:353-6. 1999
    ..The small change in circulating estrone fatty esters is consistent with the postulated role of oleoyl-estrone as a medium-term ponderostat signal...
  8. ncbi request reprint Intestinal handling of an oral oleoyl-estrone gavage by the rat
    M Esteve
    Centre Especial de Recerca en Nutricio i Ciencia dels Aliments, Facultat de Biologia, Universitat de Barcelona, Spain
    Life Sci 69:763-77. 2001
    ..It may be inferred that the HDL fraction contains the physiological carrier of oleoyl-estrone in its role of ponderostat signal...
  9. ncbi request reprint Oleoyl-estrone does not have direct estrogenic effects on rats
    C Cabot
    , Facultat de Biologia, Universitat de Barcelona, Spain
    Life Sci 69:749-61. 2001
    ..The oral administration of OE as a slimming drug, then, do not result in estrogenic side effects over a wide range of daily doses...
  10. ncbi request reprint Weight loss with long-term intermittent treatment with oral oleoyl-estrone in lean Zucker male rats
    B García-Peláez
    Department de Nutrició i Bromatologia, Facultat de Biologia, Universitat de Barcelona, Barcelona, Spain
    Horm Metab Res 38:497-500. 2006
    ..Furthermore, treated and control males remained fertile and were able to procreate. Thus, we can conclude that intermittent OE treatment induces a cumulative weight loss in adult male rats...
  11. ncbi request reprint Effect of oral oleoyl-estrone on adipose tissue composition in male rats
    X Remesar
    Centre Especial de Recerca en Nutricio i Ciencia dels Aliments, Universitat de Barcelona, Barcelona, Spain
    Int J Obes Relat Metab Disord 26:1092-102. 2002
    ..To determine whether the oral administration of oleoyl-estrone has similar mass-decreasing effects on the main different sites of white adipose tissue (WAT)...
  12. ncbi request reprint The administration of oleoyl-estrone to lactating dams induces selective changes in the normal growth pattern of their pups
    B García-Peláez
    Departament de Nutrició i Bromatologia, Facultat de Biologia, Universitat de Barcelona, Barcelona, Spain
    Horm Metab Res 39:582-8. 2007
    ..Thus, treatment affects dams in a selective way that does not coincide with a simple food restriction model...
  13. ncbi request reprint Anomalous lipoproteins in obese Zucker rats
    M Blay
    , , Universitat de Barcelona, Av. Diagonal 645, 08028 Barcelona, Spain
    Diabetes Obes Metab 3:259-70. 2001
    ....
  14. ncbi request reprint Short-term effects of a hypocaloric diet on nitrogen excretion in morbid obese women
    R Vila
    Centre de Recerca en Nutrició i Ciència dels Aliments, Facultat de Biologia, Universitat de Barcelona, Spain
    Eur J Clin Nutr 55:186-91. 2001
    ..To determine whether the daily pattern of urine excretion of N wastes is affected by obesity and very low-calorie diets (VLCD)...
  15. ncbi request reprint Effect of 24-h food deprivation on lipoprotein composition and oleoyl-estrone content of lean and obese Zucker rats
    J Peinado-Onsurbe
    Centre Especial de Recerca en Nutricio i Ciencia dels Aliments, Departament de Bioquimica i Biologia Molecular, Universitat de Barcelona, Spain
    Eur J Nutr 40:155-60. 2001
    ..Zucker obese rats are grossly hyperlipidemic and do not use lipids as an efficient energy substrate. They also have lower circulating levels of acyl-estrone than expected because of their large fat stores...
  16. ncbi request reprint Dietary oleoyl-estrone delays the growth rate of young rats
    V Tang
    Centre Especial de Recerca en Nutrició i Ciència dels Aliments Departament de Bioquímica i Biologia Molecular, Facultat de Biologia, Universitat de Barcelona Av Diagonal, 645 08028 Barcelona, Spain
    Eur J Nutr 40:17-22. 2001
    ..Oleoyl-estrone administration induces the rapid loss of fat preserving body protein...
  17. ncbi request reprint Oleoyl-estrone lowers the body weight of both ob/ob and db/db mice
    M M Grasa
    , Universitat de Barcelona, Spain
    Horm Metab Res 32:246-50. 2000
    ....
  18. ncbi request reprint Zucker obese rats store less acyl-estrone than lean controls
    R M Massanés
    Centre de Recerca en Nutrició i Cièncias dels Aliments, Facultat de Biologia, Universitat de Barcelona, Spain
    Int J Obes Relat Metab Disord 27:428-32. 2003
    ..We also examined the effect of pharmacological treatment with oral oleoyl-estrone on the accumulation of estrone...
  19. ncbi request reprint Lipoprotein lipase and cholesterol transfer activities of lean and obese Zucker rats
    J Peinado-Onsurbe
    Centre de Recerca en Nutrició i Ciència dels Aliments, Facultat de Biologia, Universitat de Barcelona, Av Diagonal 645, 08028 Barcelona, Spain
    Horm Metab Res 33:458-62. 2001
    ..In conclusion, the essentially maintained enzyme activities in obese rat tissues suggest that they cannot explain the deficient lipoproteins processing of obese rats, and, consequently their dislipidaemia...
  20. ncbi request reprint Distribution of oleoyl-estrone in rat plasma lipoproteins
    J Virgili
    , Facultat de Biologia, Universitat de Barcelona, Spain
    Horm Metab Res 31:597-601. 1999
    ..The results presented show that oleoyl-estrone is a molecule found naturally in rat lipoproteins in low concentrations - the lowest in HDLs - that are consistent with its postulated role in the control of body weight...
  21. ncbi request reprint Modulation by leptin, insulin and corticosterone of oleoyl-estrone synthesis in cultured 3T3 L1 cells
    M Esteve
    Centre Especial de Recerca en Nutricio i Ciencia dels Aliments, Facultat de Biologia, Universitat de Barcelona, Spain
    Biosci Rep 21:755-63. 2001
    ..The latter may be affected by insulin, but leptin and corticosterone enhance the process...
  22. ncbi request reprint Corticosteroid-binding globulin synthesis and distribution in rat white adipose tissue
    M del Mar Grasa
    , Facultat de Biologia, Universitat de Barcelona, Spain
    Mol Cell Biochem 228:25-31. 2001
    ..These data suggest that the CBG layer surrounding the cells may act as a protective barrier limiting the access of glucocorticoids to adipocytes...
  23. ncbi request reprint Modulation of corticosterone availability to white adipose tissue of lean and obese Zucker rats by corticosteroid-binding globulin
    M M Grasa
    , Facultat de Biologia, Universitat de Barcelona, Spain
    Horm Metab Res 33:407-11. 2001
    ..The modulation of CBG by fatty acids may protect fat reserves by decreasing the sensitivity of WAT to glucocorticoids...
  24. ncbi request reprint Splanchnic amino acid balance is affected by moderate variations of dietary protein in the developing Zucker rat
    R M Masanés
    Group Nitrogen Obesitat, Department de Bioquimica i Biologia Molecular, Facultat de Biologia, Universitat de Barcelona, Barcelona, Spain
    Int J Food Sci Nutr 52:183-92. 2001
    ..On the other hand, excess of dietary amino acids in the HP group seems to promote a lower utilization of Gln by intestine probably due to an increased release of Ala instead of Gln from peripheral tissues...
  25. ncbi request reprint Absorption of a protein gavage in Zucker lean rats. Influence of protein content in the diet
    R M Masanés
    Departament de Bioquimica i Biologia Molecular, Facultat de Biologia, Universitat de Barcelona, Spain
    Arch Physiol Biochem 109:168-74. 2001
    ..The LP group digested protein much more slowly than the RD (control) group, but protein accretion was more efficient...
  26. ncbi request reprint Changes in UCP expression in tissues of Zucker rats fed diets with different protein content
    R M Masanés
    Departament de Bioquimica i Biologia Molecular, Facultat de Biologia, Universitat de Barcelona, 08028 Barcelona, Spain
    J Physiol Biochem 58:135-41. 2002
    ..Thus, expression of UCPs can be modified by dietary protein content, in lean and obese rats. A possible thermogenic function of UCP3 in muscle and WAT in obese rats must be taken into account...
  27. ncbi request reprint Different uptake and handling of oleoyl-estrone by fetuses and neonatal rats
    B García-Peláez
    Departament de Nutrició i Bromatologia, Facultat de Biologia, Universitat de Barcelona, Barcelona, Spain
    Horm Metab Res 39:278-81. 2007
    ..On the other hand, oleoyl-estrone is easily transferred from dams to pups, as a component of milk...
  28. ncbi request reprint Urinary free cortisol excretion pattern in morbid obese women
    R Vila
    Centre de Recerca en Nutrició i Ciència dels Aliments, Facultat de Biologia, Universitat de Barcelona, Spain
    Endocr Res 27:261-8. 2001
    ..The data also show the significant influence of dietary energy on the pattern of cortisol excretion in obese women...
  29. ncbi request reprint Effect of oral oleoyl-estrone treatment on plasma lipoproteins and tissue lipase activities of Zucker lean and obese female rats
    M Blay
    Centre Especial de Recerca en Nutricio i Ciencia dels Aliments, Facultat de Biologia, Universitat de Barcelona, Barcelona, Spain
    Int J Obes Relat Metab Disord 26:618-26. 2002
    ..To study the effect of oral oleoyl-estrone on the plasma lipoprotein profile and tissue lipase activities in order to determine the handling of circulating lipids by adipose tissue, liver and muscle of obese female rats...