Eduard Montanya

Summary

Affiliation: Universitat de Barcelona
Country: Spain

Publications

  1. doi request reprint A comparison of currently available GLP-1 receptor agonists for the treatment of type 2 diabetes
    Eduard Montanya
    Endocrine Unit, Hospital Universitari Bellvitge IDIBELL, Barcelona, Spain
    Expert Opin Pharmacother 13:1451-67. 2012
  2. doi request reprint A review of efficacy and safety data regarding the use of liraglutide, a once-daily human glucagon-like peptide 1 analogue, in the treatment of type 2 diabetes mellitus
    Eduard Montanya
    Endocrine Unit, University Hospital of Bellvitge, Institut d Investigacio Biomedica de Bellvitge, Barcelona, Spain
    Clin Ther 31:2472-88. 2009
  3. ncbi request reprint Islet- and stem-cell-based tissue engineering in diabetes
    Eduard Montanya
    Endocrine Unit, Hospital Universitari Bellvitge, Feixa Llarga s n, 08907 L Hospitalet de Llobregat, Barcelona, Spain
    Curr Opin Biotechnol 15:435-40. 2004
  4. doi request reprint Pancreatic remodeling: beta-cell apoptosis, proliferation and neogenesis, and the measurement of beta-cell mass and of individual beta-cell size
    Eduard Montanya
    Endocrine Unit, University Hospital of Bellvitge, Barcelona, Spain
    Methods Mol Biol 560:137-58. 2009
  5. ncbi request reprint Short-term culture with the caspase inhibitor z-VAD.fmk reduces beta cell apoptosis in transplanted islets and improves the metabolic outcome of the graft
    Marta Montolio
    Laboratory of Diabetes and Experimental Endocrinology, Endocrine Unit, IDIBELL Hospital Universitari de Bellvitge, University of Barcelona, Barcelona, Spain
    Cell Transplant 14:59-65. 2005
  6. doi request reprint Gastrin treatment stimulates β-cell regeneration and improves glucose tolerance in 95% pancreatectomized rats
    Noelia Téllez
    Laboratory of Diabetes and Experimental Endocrinology, Department of Clinical Sciences, University of Barcelona, Hospital Universitari de Bellvitge, Feixa Llarga s n, 08907 L Hospitalet de Llobregat, Barcelona Spain
    Endocrinology 152:2580-8. 2011
  7. ncbi request reprint Interleukin-1beta and inducible form of nitric oxide synthase expression in early syngeneic islet transplantation
    Marta Montolio
    Institut d Investigacio Biomedica de Bellvitge, Endocrine Unit, Hospital Universitari de Bellvitge, Barcelona, Spain
    J Endocrinol 192:169-77. 2007
  8. doi request reprint Increased β-cell replication and β-cell mass regeneration in syngeneically transplanted rat islets overexpressing insulin-like growth factor II
    Elisabet Estil les
    Laboratory of Diabetes and Experimental Endocrinology, Department of Clinical Sciences, IDIBELL University of Barcelona, Barcelona, Spain
    Cell Transplant 21:2119-29. 2012
  9. ncbi request reprint Islet graft response to transplantation injury includes upregulation of protective as well as apoptotic genes
    Silvia Rodriguez-Mulero
    Laboratory of Diabetes and Experimental Endocrinology, Clinical Science Department, IDIBELL University of Barcelona, Barcelona, Spain
    Cell Transplant 17:1025-34. 2008
  10. doi request reprint Glucose-dependent changes in SNARE protein levels in pancreatic β-cells
    Benjamín Torrejón-Escribano
    Departamento de Patologia i Terapèutica Experimental, Institut d Investigació Biomèdica de Bellvitge Universitat de Barcelona, Laboratori 4145, Campus de Bellvitge, Edifici del Pavelló de Govern, c Feixa Llarga s n, 08907 L Hospitalet de Llobregat, Barcelona, Spain
    Endocrinology 152:1290-9. 2011

Collaborators

  • G Sesti
  • Noelia Téllez
  • Anna Novials
  • Marta Montolio
  • Elisabet Estil les
  • Joan Soler
  • Silvia Rodriguez-Mulero
  • Jessica Escoriza
  • Montserrat Nacher
  • Benjamín Torrejón-Escribano
  • Montserrat Biarnés
  • Manuel Pérez-Maraver
  • Ainhoa García
  • Cristofer Garcia
  • Belen Nadal
  • Mar Pairó
  • Lluís Secanella
  • Juan Blasi
  • Montse Biarnés
  • Cayetano Vinzia
  • Maria Jose Carrera
  • Manuel Sahun
  • Teresa Micaló
  • Victor Nacher
  • Mercè Raurell

Detail Information

Publications18

  1. doi request reprint A comparison of currently available GLP-1 receptor agonists for the treatment of type 2 diabetes
    Eduard Montanya
    Endocrine Unit, Hospital Universitari Bellvitge IDIBELL, Barcelona, Spain
    Expert Opin Pharmacother 13:1451-67. 2012
    ..GLP-1 receptor agonists also offer weight-loss benefits. Because GLP-1 receptor agonists are relatively new agents, there is limited direction on their use...
  2. doi request reprint A review of efficacy and safety data regarding the use of liraglutide, a once-daily human glucagon-like peptide 1 analogue, in the treatment of type 2 diabetes mellitus
    Eduard Montanya
    Endocrine Unit, University Hospital of Bellvitge, Institut d Investigacio Biomedica de Bellvitge, Barcelona, Spain
    Clin Ther 31:2472-88. 2009
    ..Liraglutide, a human glucagon-like peptide 1 (GLP-1) analogue that has received marketing approval from the European Commission, is a treatment for type 2 diabetes mellitus (DM) that is administered as a once-daily subcutaneous injection...
  3. ncbi request reprint Islet- and stem-cell-based tissue engineering in diabetes
    Eduard Montanya
    Endocrine Unit, Hospital Universitari Bellvitge, Feixa Llarga s n, 08907 L Hospitalet de Llobregat, Barcelona, Spain
    Curr Opin Biotechnol 15:435-40. 2004
    ..A much better understanding of the processes that govern the expansion and differentiation of stem cells is needed...
  4. doi request reprint Pancreatic remodeling: beta-cell apoptosis, proliferation and neogenesis, and the measurement of beta-cell mass and of individual beta-cell size
    Eduard Montanya
    Endocrine Unit, University Hospital of Bellvitge, Barcelona, Spain
    Methods Mol Biol 560:137-58. 2009
    ..Point counting morphometry is used to estimate beta-cell mass and planimetry to determine the cross-sectional area of individual beta-cells, a measure of beta-cell size...
  5. ncbi request reprint Short-term culture with the caspase inhibitor z-VAD.fmk reduces beta cell apoptosis in transplanted islets and improves the metabolic outcome of the graft
    Marta Montolio
    Laboratory of Diabetes and Experimental Endocrinology, Endocrine Unit, IDIBELL Hospital Universitari de Bellvitge, University of Barcelona, Barcelona, Spain
    Cell Transplant 14:59-65. 2005
    ..10 +/- 0.02 mg) (p = 0.043). In summary, the treatment of freshly isolated islets with the caspase inhibitor z-VAD.fmk reduced the subsequent apoptosis of the islets once they were transplanted and improved the outcome of the graft...
  6. doi request reprint Gastrin treatment stimulates β-cell regeneration and improves glucose tolerance in 95% pancreatectomized rats
    Noelia Téllez
    Laboratory of Diabetes and Experimental Endocrinology, Department of Clinical Sciences, University of Barcelona, Hospital Universitari de Bellvitge, Feixa Llarga s n, 08907 L Hospitalet de Llobregat, Barcelona Spain
    Endocrinology 152:2580-8. 2011
    ..07 ± 0.02%, Px+V: 0.23 ± 0.05%; P < 0.05). Gastrin action on β-cell regeneration and survival increased β-cell mass and improved glucose tolerance in 95% Px rats, supporting a potential role of gastrin in the treatment of diabetes...
  7. ncbi request reprint Interleukin-1beta and inducible form of nitric oxide synthase expression in early syngeneic islet transplantation
    Marta Montolio
    Institut d Investigacio Biomedica de Bellvitge, Endocrine Unit, Hospital Universitari de Bellvitge, Barcelona, Spain
    J Endocrinol 192:169-77. 2007
    ..Overall, the data suggest that IL-1beta plays a role in the extensive beta-cell death found in the initial days after islet transplantation...
  8. doi request reprint Increased β-cell replication and β-cell mass regeneration in syngeneically transplanted rat islets overexpressing insulin-like growth factor II
    Elisabet Estil les
    Laboratory of Diabetes and Experimental Endocrinology, Department of Clinical Sciences, IDIBELL University of Barcelona, Barcelona, Spain
    Cell Transplant 21:2119-29. 2012
    ....
  9. ncbi request reprint Islet graft response to transplantation injury includes upregulation of protective as well as apoptotic genes
    Silvia Rodriguez-Mulero
    Laboratory of Diabetes and Experimental Endocrinology, Clinical Science Department, IDIBELL University of Barcelona, Barcelona, Spain
    Cell Transplant 17:1025-34. 2008
    ....
  10. doi request reprint Glucose-dependent changes in SNARE protein levels in pancreatic β-cells
    Benjamín Torrejón-Escribano
    Departamento de Patologia i Terapèutica Experimental, Institut d Investigació Biomèdica de Bellvitge Universitat de Barcelona, Laboratori 4145, Campus de Bellvitge, Edifici del Pavelló de Govern, c Feixa Llarga s n, 08907 L Hospitalet de Llobregat, Barcelona, Spain
    Endocrinology 152:1290-9. 2011
    ..Altogether, the results suggest that high glucose has a direct toxic effect on the secretory pathway by decreasing the expression of insulin granule SNARE-associated proteins...
  11. doi request reprint High sensitivity of beta-cell replication to the inhibitory effects of interleukin-1beta: modulation by adenoviral overexpression of IGF2 in rat islets
    Elisabet Estil les
    Laboratory of Diabetes and Experimental Endocrinology, Department of Clinical Sciences, IDIBELL University of Barcelona, Feixa Llarga s n 08907 L Hospitalet de Llobregat, Barcelona, Spain
    J Endocrinol 203:55-63. 2009
    ....
  12. ncbi request reprint Beta-cell death and mass in syngeneically transplanted islets exposed to short- and long-term hyperglycemia
    Montserrat Biarnés
    Laboratory of Diabetes and Experimental Endocrinology, Endocrine Unit, CSUB Hospital de Bellvitge, University of Barcelona, Barcelona, Spain
    Diabetes 51:66-72. 2002
    ..Increased apoptosis and reduced beta-cell mass were also found in islets exposed to chronic hyperglycemia, suggesting that sustained hyperglycemia increased apoptosis in transplanted beta-cells...
  13. ncbi request reprint Renoprotective effect of diltiazem in hypertensive type 2 diabetic patients with persistent microalbuminuria despite ACE inhibitor treatment
    Manuel Pérez-Maraver
    Endocrine Unit 13 2, Hospital Universitari Bellvitge, Feixa Llarga s n, 08907 L Hospitalet de Llobregat, Barcelona, Spain
    Diabetes Res Clin Pract 70:13-9. 2005
    ..We suggest that the combination of ACE inhibitors and NDCA should be considered in type 2 microalbuminuric patients at high risk for progression to established diabetic nephropathy...
  14. doi request reprint β-Cell dedifferentiation, reduced duct cell plasticity, and impaired β-cell mass regeneration in middle-aged rats
    Noelia Téllez
    CIBER of Diabetes and Associated Metabolic Diseases, CIBERDEM, Barcelona, Spain Bellvitge Biomedical Research Institute, IDIBELL, Barcelona, Spain Department of Clinical Sciences, University of Barcelona, L Hospitalet de Llobregat, Barcelona, Spain
    Am J Physiol Endocrinol Metab 311:E554-63. 2016
    ..In summary, the potential for compensatory β-cell hyperplasia and hypertrophy was retained in middle-aged rats, but β-cell dedifferentiation and impaired duct cell plasticity limited β-cell regeneration. ..
  15. doi request reprint Human Serum Versus Human Serum Albumin Supplementation in Human Islet Pretransplantation Culture: In Vitro and In Vivo Assessment
    Montserrat Nacher
    Hospital Universitari Bellvitge IDIBELLL, Hospitalet de Llobregat, Barcelona, Spain
    Cell Transplant 25:343-52. 2016
    ..However, the beneficial effect on viability and function did not translate into an improved metabolic evolution when a similar number of HSA- and HS-cultured islets was transplanted. ..
  16. doi request reprint Gastrin induces ductal cell dedifferentiation and β-cell neogenesis after 90% pancreatectomy
    Noelia Téllez
    CIBER of Diabetes and Metabolic DiseasesCIBERDEM, Barcelona, SpainBellvitge Biomedical Research InstituteIDIBELL, L Hospitalet de Llobregat, Barcelona, SpainEndocrine UnitHospital Universitari de Bellvitge, L Hospitalet de Llobregat, Barcelona, SpainDepartment of Clinical SciencesUniversity of Barcelona, L Hospitalet de Llobregat, Barcelona, Spain CIBER of Diabetes and Metabolic DiseasesCIBERDEM, Barcelona, SpainBellvitge Biomedical Research InstituteIDIBELL, L Hospitalet de Llobregat, Barcelona, SpainEndocrine UnitHospital Universitari de Bellvitge, L Hospitalet de Llobregat, Barcelona, SpainDepartment of Clinical SciencesUniversity of Barcelona, L Hospitalet de Llobregat, Barcelona, Spain CIBER of Diabetes and Metabolic DiseasesCIBERDEM, Barcelona, SpainBellvitge Biomedical Research InstituteIDIBELL, L Hospitalet de Llobregat, Barcelona, SpainEndocrine UnitHospital Universitari de Bellvitge, L Hospitalet de Llobregat, Barcelona, SpainDepartment of Clinical SciencesUniversity of Barcelona, L Hospitalet de Llobregat, Barcelona, Spain
    J Endocrinol 223:67-78. 2014
    ..These results indicate that gastrin treatment-enhanced dedifferentiation and reprogramming of regenerative ductal cells in Px rats, increased β-cell neogenesis and fostered β-cell mass expansion. ..
  17. ncbi request reprint Role of blood glucose in cytokine gene expression in early syngeneic islet transplantation
    Marta Montolio
    Laboratory of Diabetes and Experimental Endocrinology, Department of Clinical Sciences, University of Barcelona
    Cell Transplant 16:517-25. 2007
    ..Thus, the inflammatory response in islet grafts was maximal on day 1 after transplantation, it was sustained, although at lower levels, on days 3 and 7, and it was partly enhanced by hyperglycemia...
  18. ncbi request reprint Selection of a suitable internal control gene for expression studies in pancreatic islet grafts
    Silvia Rodriguez-Mulero
    Laboratory of Diabetes and Experimental Endocrinology, Department of Medicine, IDIBELL University of Barcelona, Spain
    Transplantation 80:650-2. 2005
    ..The significant variation found in other housekeeping genes, particularly GAPDH and beta-actin, question their use as internal controls in islet grafts...