Asunción Morán

Summary

Affiliation: Universidad de Salamanca
Country: Spain

Publications

  1. doi request reprint Characterization of contractile 5-hydroxytryptamine receptor subtypes in the in situ autoperfused kidney in the anaesthetized rat
    Asunción Morán
    Departamento de Fisiologia y Farmacologia, Laboratorio de Farmacognosia y Farmacología, Facultad de Farmacia, Universidad de Salamanca, Campus Miguel de Unamuno, ES 37007, Spain
    Eur J Pharmacol 592:133-7. 2008
  2. doi request reprint Characterization of the contractile 5-hydroxytryptamine receptor in the autoperfused kidney of L-NAME hypertensive rats
    Asunción Morán
    Departamento de Fisiologia y Farmacologia, Laboratorio de Farmacognosia y Farmacología, Facultad de Farmacia, Universidad de Salamanca, Campus Miguel de Unamuno, Spain
    Eur J Pharmacol 620:90-6. 2009
  3. doi request reprint Pharmacological profile of 5-hydroxytryptamine-induced inhibition on the pressor effect elicited by sympathetic stimulation in long-term diabetic pithed rats
    Asunción Morán
    Laboratorio de Farmacologia, Departamento de Fisiologia y Farmacologia, Facultad de Farmacia, Universidad de Salamanca, 37007 Salamanca, Spain
    Eur J Pharmacol 643:70-7. 2010
  4. ncbi request reprint The nitric oxide synthesis/pathway mediates the inhibitory serotoninergic responses of the pressor effect elicited by sympathetic stimulation in diabetic pithed rats
    Monica Garcia
    Laboratorio de Farmacognosia y Farmacología, Departamento de Fisiologia y Farmacologia, Facultad de Farmacia, Universidad de Salamanca, Campus Miguel de Unamuno, ES 37007 Salamanca, Spain
    Eur J Pharmacol 537:126-34. 2006
  5. pmc Diabetes-induced changes in the 5-hydroxytryptamine inhibitory receptors involved in the pressor effect elicited by sympathetic stimulation in the pithed rat
    Monica Garcia
    Laboratorio de Farmacognosia y Farmacología, Departamento de Fisiologia y Farmacologia, Facultad de Farmacia, Universidad de Salamanca, Campus Miguel de Unamuno, ES 37007 Salamanca, Spain
    Br J Pharmacol 145:593-601. 2005
  6. doi request reprint Peripheral 5-HT₁D and 5-HT₇ serotonergic receptors modulate sympathetic neurotransmission in chronic sarpogrelate treated rats
    José Ángel García-Pedraza
    Laboratorio de Farmacologia, Departamento de Fisiologia y Farmacologia, Facultad de Farmacia, Universidad de Salamanca, 37007 Salamanca, Spain
    Eur J Pharmacol 714:65-73. 2013
  7. pmc Peripheral 5-HT1A and 5-HT7 serotonergic receptors modulate parasympathetic neurotransmission in long-term diabetic rats
    Beatriz Restrepo
    Laboratorio de Farmacologia, Departamento de Fisiologia y Farmacologia, Facultad de Farmacia, Universidad de Salamanca, Campus Miguel de Unamuno, 37007 Salamanca, Spain
    Exp Diabetes Res 2010:686734. 2010
  8. doi request reprint Participation of cyclooxygenase pathway in the vasoconstriction induced by 5-HT in the in situ autoperfused kidney of long-term diabetic rats
    Beatriz Restrepo
    Laboratorio de Farmacologia, Departamento de Fisiologia y Farmacologia, Facultad de Farmacia, Universidad de Salamanca, 37007 Salamanca, Spain Grupo de Enfermedades Cardiovasculares y Metabólicas, Facultad Ciencias de la Salud, Universidad del Quindio, Armenia, Colombia
    Eur J Pharmacol 659:37-44. 2011
  9. doi request reprint The role of endothelium-derived hyperpolarizing factor and cyclooxygenase pathways in the inhibitory serotonergic response to the pressor effect elicited by sympathetic stimulation in chronic sarpogrelate treated rats
    José Ángel García-Pedraza
    Laboratorio de Farmacologia, Departamento de Fisiologia y Farmacologia, Facultad de Farmacia, Universidad de Salamanca, 37007 Salamanca, Spain
    Eur J Pharmacol 731:80-7. 2014
  10. ncbi request reprint Chronic sarpogrelate treatment reveals 5-HT7 receptor in the serotonergic inhibition of the rat vagal bradycardia
    José Ángel García-Pedraza
    aLaboratory of Pharmacology Department of Physiology and Pharmacology, Faculty of Pharmacy University of Salamanca, 37007 Salamanca, Spain bResearch Institute of Salamanca IBSAL Paseo San Vicente 58 182, 37007, Salamanca, Spain cUnit of Cardiovascular and Renal Pathophysiology Research Institute of Nephrology Reina Sofía Department of Physiology and Pharmacology University of Salamanca, 37007, Salamanca, Spain
    J Cardiovasc Pharmacol . 2016

Collaborators

  • Carlos M Villalón
  • José Ángel García-Pedraza
  • Monica Garcia
  • María Luisa Martín
  • Beatriz Restrepo
  • Luis San Roman
  • Luis San Román
  • Cristina Cuesta
  • Alicia Rodriguez-Barbero
  • Mariette Barthelmebs
  • Nelida Eleno
  • Jesús Gómez-Escudero
  • Elena Calama

Detail Information

Publications12

  1. doi request reprint Characterization of contractile 5-hydroxytryptamine receptor subtypes in the in situ autoperfused kidney in the anaesthetized rat
    Asunción Morán
    Departamento de Fisiologia y Farmacologia, Laboratorio de Farmacognosia y Farmacología, Facultad de Farmacia, Universidad de Salamanca, Campus Miguel de Unamuno, ES 37007, Spain
    Eur J Pharmacol 592:133-7. 2008
    ..Our data suggest also that the serotonergic vasoconstrictor response induced in the in situ autoperfused rat kidney would be mediated by local 5-HT2C receptor activation...
  2. doi request reprint Characterization of the contractile 5-hydroxytryptamine receptor in the autoperfused kidney of L-NAME hypertensive rats
    Asunción Morán
    Departamento de Fisiologia y Farmacologia, Laboratorio de Farmacognosia y Farmacología, Facultad de Farmacia, Universidad de Salamanca, Campus Miguel de Unamuno, Spain
    Eur J Pharmacol 620:90-6. 2009
    ..Our data suggest that the serotonergic vasoconstrictor response induced in the in-situ autoperfused hypertensive rat kidney would be mediated by local activation of the 5-HT(2A) receptor...
  3. doi request reprint Pharmacological profile of 5-hydroxytryptamine-induced inhibition on the pressor effect elicited by sympathetic stimulation in long-term diabetic pithed rats
    Asunción Morán
    Laboratorio de Farmacologia, Departamento de Fisiologia y Farmacologia, Facultad de Farmacia, Universidad de Salamanca, 37007 Salamanca, Spain
    Eur J Pharmacol 643:70-7. 2010
    ..This is mainly mediated by pre-junctional 5-HT(1A) and 5-HT(2A) receptors...
  4. ncbi request reprint The nitric oxide synthesis/pathway mediates the inhibitory serotoninergic responses of the pressor effect elicited by sympathetic stimulation in diabetic pithed rats
    Monica Garcia
    Laboratorio de Farmacognosia y Farmacología, Departamento de Fisiologia y Farmacologia, Facultad de Farmacia, Universidad de Salamanca, Campus Miguel de Unamuno, ES 37007 Salamanca, Spain
    Eur J Pharmacol 537:126-34. 2006
    ..In conclusion, in diabetic pithed rats, the inhibition produced by prejunctional 5-HT(1A) activation on electrically induced sympathetic pressor responses is mediated by the NO synthesis/pathway...
  5. pmc Diabetes-induced changes in the 5-hydroxytryptamine inhibitory receptors involved in the pressor effect elicited by sympathetic stimulation in the pithed rat
    Monica Garcia
    Laboratorio de Farmacognosia y Farmacología, Departamento de Fisiologia y Farmacologia, Facultad de Farmacia, Universidad de Salamanca, Campus Miguel de Unamuno, ES 37007 Salamanca, Spain
    Br J Pharmacol 145:593-601. 2005
    ....
  6. doi request reprint Peripheral 5-HT₁D and 5-HT₇ serotonergic receptors modulate sympathetic neurotransmission in chronic sarpogrelate treated rats
    José Ángel García-Pedraza
    Laboratorio de Farmacologia, Departamento de Fisiologia y Farmacologia, Facultad de Farmacia, Universidad de Salamanca, 37007 Salamanca, Spain
    Eur J Pharmacol 714:65-73. 2013
    ..The antagonism of 5-HT₂ receptors produces an enhancement of serotonergic sympathoinhibitory effect, which may explain the beneficial effects of this blockade in cardiovascular disorders where 5-hydroxytryptamine plays a crucial role...
  7. pmc Peripheral 5-HT1A and 5-HT7 serotonergic receptors modulate parasympathetic neurotransmission in long-term diabetic rats
    Beatriz Restrepo
    Laboratorio de Farmacologia, Departamento de Fisiologia y Farmacologia, Facultad de Farmacia, Universidad de Salamanca, Campus Miguel de Unamuno, 37007 Salamanca, Spain
    Exp Diabetes Res 2010:686734. 2010
    ..Activation of the 5-HT(1A) receptors induces enhancement, whereas attenuation is due to 5-HT(7) receptor activation. This 5-HT dual effect occurs at pre- and postjunctional levels...
  8. doi request reprint Participation of cyclooxygenase pathway in the vasoconstriction induced by 5-HT in the in situ autoperfused kidney of long-term diabetic rats
    Beatriz Restrepo
    Laboratorio de Farmacologia, Departamento de Fisiologia y Farmacologia, Facultad de Farmacia, Universidad de Salamanca, 37007 Salamanca, Spain Grupo de Enfermedades Cardiovasculares y Metabólicas, Facultad Ciencias de la Salud, Universidad del Quindio, Armenia, Colombia
    Eur J Pharmacol 659:37-44. 2011
    ..Our data suggest that, in the in-situ autoperfused kidney of long-term diabetic rats, 5-HT vasoconstrictor action is mediated, through cyclooxygenase pathway, by local activation of 5-HT2A receptors...
  9. doi request reprint The role of endothelium-derived hyperpolarizing factor and cyclooxygenase pathways in the inhibitory serotonergic response to the pressor effect elicited by sympathetic stimulation in chronic sarpogrelate treated rats
    José Ángel García-Pedraza
    Laboratorio de Farmacologia, Departamento de Fisiologia y Farmacologia, Facultad de Farmacia, Universidad de Salamanca, 37007 Salamanca, Spain
    Eur J Pharmacol 731:80-7. 2014
    ....
  10. ncbi request reprint Chronic sarpogrelate treatment reveals 5-HT7 receptor in the serotonergic inhibition of the rat vagal bradycardia
    José Ángel García-Pedraza
    aLaboratory of Pharmacology Department of Physiology and Pharmacology, Faculty of Pharmacy University of Salamanca, 37007 Salamanca, Spain bResearch Institute of Salamanca IBSAL Paseo San Vicente 58 182, 37007, Salamanca, Spain cUnit of Cardiovascular and Renal Pathophysiology Research Institute of Nephrology Reina Sofía Department of Physiology and Pharmacology University of Salamanca, 37007, Salamanca, Spain
    J Cardiovasc Pharmacol . 2016
    ..Our outcomes suggest that blocking chronically 5-HT2 receptors modifies the serotonergic influence on cardiac vagal neurotransmission exhibiting 5-HT as an exclusively inhibitory agent via prejunctional 5-HT7 receptor...
  11. doi request reprint 5-HT1D receptor inhibits renal sympathetic neurotransmission by nitric oxide pathway in anesthetized rats
    José Ángel García-Pedraza
    Laboratorio de Farmacologia, Departamento de Fisiologia y Farmacologia, Facultad de Farmacia, Universidad de Salamanca, 37007 Salamanca, Spain
    Vascul Pharmacol 72:172-80. 2015
    ..These results suggest that 5-HT mechanism-induced inhibition of rat vasopressor renal sympathetic outflow is mainly mediated by prejunctional 5-HT1D receptors via nitric oxide release. ..
  12. doi request reprint Role of 5-HT7 receptors in the inhibition of the vasodepressor sensory CGRPergic outflow in pithed rats
    Cristina Cuesta
    Laboratorio de Farmacologia, Departamento de Fisiologia y Farmacologia, Facultad de Farmacia, Universidad de Salamanca, Campus Miguel de Unamuno, ES 37007 Salamanca, Spain
    Vascul Pharmacol 63:4-12. 2014
    ..The present results suggest that AS-19-induced inhibition of the rat vasodepressor sensory CGRPergic outflow is mainly mediated by 5-HT7 receptors via endothelin release, with the possible involvement of ATP-dependent K(+) channels. ..