Ana I Esquifino

Summary

Affiliation: Universidad Complutense
Country: Spain

Publications

  1. pmc Prolactin daily rhythm in suckling male rabbits
    Pilar Alvarez
    Departamento de Bioquimica y Biologia Molecular III, Facultad de Medicina, Universidad Complutense de Madrid, 28040 Madrid, Spain
    J Circadian Rhythms 3:1. 2005
  2. pmc Effect of litter separation on 24-hour rhythmicity of plasma prolactin, follicle-stimulating hormone and luteinizing hormone levels in lactating rabbit does
    Pilar Cano
    Departamento de Bioquimica y Biologia Molecular III, Facultad de Medicina, Universidad Complutense de Madrid, 28040 Madrid, Spain
    J Circadian Rhythms 3:9. 2005
  3. pmc Experimental allergic encephalomyelitis in pituitary-grafted Lewis rats
    Ana I Esquifino
    Departamento de Bioquimica y Biologia Molecular III, Facultad de Medicina, Universidad Complutense de Madrid, Spain
    J Neuroinflammation 3:20. 2006
  4. pmc d24-hour changes in circulating prolactin, follicle-stimulating hormone, luteinizing hormone and testosterone in male rats subjected to social isolation
    Ana I Esquifino
    Departamento de Fisiologia, Facultad de Medicina, Universidad de Buenos Aires, Buenos Aires, Argentina
    J Circadian Rhythms 2:1. 2004
  5. ncbi request reprint Superior cervical ganglionectomy differentially modifies median eminence and anterior and mediobasal hypothalamic GABA content in male rats: effects of hyperprolactinemia
    A I Esquifino
    Departamento de Bioquimica y Biologia Molecular III, Facultad de Medicina, Universidad Complutense, Ciudad Universitaria, 28040, Madrid, Spain
    Exp Brain Res 157:296-302. 2004
  6. ncbi request reprint Differential effects of light/dark recombinant human prolactin administration on the submaxillary lymph nodes and spleen activity of adult male mice
    A I Esquifino
    Departamento de Bioquimica y Biologia Molecular III, Facultad de Medicina Universidad Complutense, Madrid, Espana
    Neuroimmunomodulation 11:119-26. 2004
  7. ncbi request reprint Changes of prolactin regulatory mechanisms in aging: 24-h rhythms of serum prolactin and median eminence and adenohypophysial concentration of dopamine, serotonin, (gamma-aminobutyric acid, taurine and somatostatin in young and aged rats
    A I Esquifino
    Departamento de Bioquimica y Biologia Molecular III, Facultad de Medicina, Universidad Complutense, Madrid 28040, Spain
    Exp Gerontol 39:45-52. 2004
  8. ncbi request reprint Superior cervical ganglionectomy effects on median eminence and anterior and mediobasal hypothalamic taurine content in male rats: effects of hyperprolactinemia
    A I Esquifino
    Departamento de Bioquimica y Biologia Molecular III, Facultad de Medicina, Universidad Complutense Madrid, Madrid, Spain
    Neurosignals 12:95-102. 2003
  9. ncbi request reprint Experimental allergic encephalomyelitis in male Lewis rats subjected to calorie restriction
    A I Esquifino
    Depto de Bioquímica y Biología Molecular III, Facultad de Medicina, Universidad Complutense, Avda Complutense s n, 28040 Madrid, Spain
    J Physiol Biochem 60:245-52. 2004
  10. ncbi request reprint Neuroendocrine-immune correlates of circadian physiology: studies in experimental models of arthritis, ethanol feeding, aging, social isolation, and calorie restriction
    Ana I Esquifino
    Departamento de Bioquimica y Biologia Molecular III, Facultad de Medicina, Universidad Complutense, 28040, Madrid, Spain
    Endocrine 32:1-19. 2007

Collaborators

Detail Information

Publications40

  1. pmc Prolactin daily rhythm in suckling male rabbits
    Pilar Alvarez
    Departamento de Bioquimica y Biologia Molecular III, Facultad de Medicina, Universidad Complutense de Madrid, 28040 Madrid, Spain
    J Circadian Rhythms 3:1. 2005
    ..CONCLUSION: The correlations among the changes in the neurotransmitters analyzed and circulating prolactin levels explain the circadian secretory pattern of the hormone in newborn male rabbits...
  2. pmc Effect of litter separation on 24-hour rhythmicity of plasma prolactin, follicle-stimulating hormone and luteinizing hormone levels in lactating rabbit does
    Pilar Cano
    Departamento de Bioquimica y Biologia Molecular III, Facultad de Medicina, Universidad Complutense de Madrid, 28040 Madrid, Spain
    J Circadian Rhythms 3:9. 2005
    ..This work describes the effect of a 48-h litter separation on 24-h patterns of plasma prolactin, FSH and LH concentration in female lactating rabbits kept under a 16:8 light-dark photoperiod (lights on at 0800 h)...
  3. pmc Experimental allergic encephalomyelitis in pituitary-grafted Lewis rats
    Ana I Esquifino
    Departamento de Bioquimica y Biologia Molecular III, Facultad de Medicina, Universidad Complutense de Madrid, Spain
    J Neuroinflammation 3:20. 2006
    ..These results indicate that low circulating prolactin levels coincide with absence of clinical signs of EAE in Lewis rats...
  4. pmc d24-hour changes in circulating prolactin, follicle-stimulating hormone, luteinizing hormone and testosterone in male rats subjected to social isolation
    Ana I Esquifino
    Departamento de Fisiologia, Facultad de Medicina, Universidad de Buenos Aires, Buenos Aires, Argentina
    J Circadian Rhythms 2:1. 2004
    ..The maximum in circulating testosterone taking place at the second part of the rest span in controls is phase-delayed to the light-dark transition in isolated rats...
  5. ncbi request reprint Superior cervical ganglionectomy differentially modifies median eminence and anterior and mediobasal hypothalamic GABA content in male rats: effects of hyperprolactinemia
    A I Esquifino
    Departamento de Bioquimica y Biologia Molecular III, Facultad de Medicina, Universidad Complutense, Ciudad Universitaria, 28040, Madrid, Spain
    Exp Brain Res 157:296-302. 2004
    ..Induction of hyperprolactinemia in the neonatal age interferes with SCGx effects on both GABA content within the hypothalamus and median eminence and the secretory patterns of the pituitary hormones studied...
  6. ncbi request reprint Differential effects of light/dark recombinant human prolactin administration on the submaxillary lymph nodes and spleen activity of adult male mice
    A I Esquifino
    Departamento de Bioquimica y Biologia Molecular III, Facultad de Medicina Universidad Complutense, Madrid, Espana
    Neuroimmunomodulation 11:119-26. 2004
    ....
  7. ncbi request reprint Changes of prolactin regulatory mechanisms in aging: 24-h rhythms of serum prolactin and median eminence and adenohypophysial concentration of dopamine, serotonin, (gamma-aminobutyric acid, taurine and somatostatin in young and aged rats
    A I Esquifino
    Departamento de Bioquimica y Biologia Molecular III, Facultad de Medicina, Universidad Complutense, Madrid 28040, Spain
    Exp Gerontol 39:45-52. 2004
    ..Median eminence and pituitary 5HT and taurine content did not change with age. The results indicate disruption of prolactin regulatory mechanisms with aging in rats...
  8. ncbi request reprint Superior cervical ganglionectomy effects on median eminence and anterior and mediobasal hypothalamic taurine content in male rats: effects of hyperprolactinemia
    A I Esquifino
    Departamento de Bioquimica y Biologia Molecular III, Facultad de Medicina, Universidad Complutense Madrid, Madrid, Spain
    Neurosignals 12:95-102. 2003
    ....
  9. ncbi request reprint Experimental allergic encephalomyelitis in male Lewis rats subjected to calorie restriction
    A I Esquifino
    Depto de Bioquímica y Biología Molecular III, Facultad de Medicina, Universidad Complutense, Avda Complutense s n, 28040 Madrid, Spain
    J Physiol Biochem 60:245-52. 2004
    ..The results are compatible with the view that the course of EAE can be significantly modified by caloric restriction...
  10. ncbi request reprint Neuroendocrine-immune correlates of circadian physiology: studies in experimental models of arthritis, ethanol feeding, aging, social isolation, and calorie restriction
    Ana I Esquifino
    Departamento de Bioquimica y Biologia Molecular III, Facultad de Medicina, Universidad Complutense, 28040, Madrid, Spain
    Endocrine 32:1-19. 2007
    ..In every case the experimental manipulation used perturbed the temporal organization by affecting the shape and amplitude of a rhythm or by modifying the intrinsic oscillatory mechanism itself...
  11. ncbi request reprint 24-hour pattern of circulating prolactin and growth hormone levels and submaxillary lymph node immune responses in growing male rats subjected to social isolation
    Ana I Esquifino
    Departamento de Bioquimica y Biologia Molecular III, Facultad de Medicina, Universidad Complutense, 28040 Madrid, Spain
    Endocrine 25:41-8. 2004
    ..Modifications in mean value and 24-h rhythmicity of plasma prolactin and GH levels are presumably involved in the effect of social isolation on immune responsiveness...
  12. pmc Effect of rabbit doe-litter separation on 24-hour changes of luteinizing hormone, follicle stimulating hormone and prolactin release in female and male suckling pups
    Pilar Cano
    Departamento de Bioquimica y Biologia Molecular III, Facultad de Medicina, Universidad Complutense de Madrid, Spain
    Reprod Biol Endocrinol 3:50. 2005
    ..e., 48 h) doe-litter separation...
  13. pmc Immune response after experimental allergic encephalomyelitis in rats subjected to calorie restriction
    Ana I Esquifino
    Departamento de Bioquimica y Biologia Molecular III, Facultad de Medicina, Universidad Complutense, Madrid, Spain
    J Neuroinflammation 4:6. 2007
    ..The results are compatible with the view that the acute phase of EAE can be curtailed by severe calorie restriction, presumably through impaired IFN-gamma production...
  14. doi request reprint Continuous versus discontinuous drinking of an ethanol liquid diet in peripubertal rats: effect on 24-h variation of lymph node and splenic mitogenic responses and lymphocyte subset populations
    Vanesa Jimenez-Ortega
    Department of Biochemistry and Molecular Biology III, Faculty of Medicine, Universidad Complutense, Madrid 28040, Spain
    Alcohol 45:183-92. 2011
    ....
  15. ncbi request reprint Effect of ethanol on 24-h hormonal changes in prolactin release mechanisms in growing male rats
    Vanesa Jimenez-Ortega
    Departamento de Bioquimica y Biologia Molecular III, Facultad de Medicina, Universidad Complutense, 28040 Madrid, Spain
    Endocrine 30:269-78. 2006
    ..Ethanol augmented pituitary levels of DOPAC and 5-HIAA. The results indicate that chronic ethanol administration affects the mechanisms that modulate the circadian variation of prolactin release in growing male rats...
  16. ncbi request reprint Effect of interferon-gamma treatment on 24-hour variations in plasma ACTH, growth hormone, prolactin, luteinizing hormone and follicle-stimulating hormone of male rats
    Pilar Cano
    Departamento de Bioquimica y Biologia Molecular III, Facultad de Medicina, Universidad Complutense, Madrid, Espana
    Neuroimmunomodulation 12:146-51. 2005
    ..In this study we measured the circadian pattern of plasma ACTH, growth hormone (GH), prolactin, luteinizing hormone (LH) and follicle-stimulating hormone (FSH) at 6 different time points within a 24-hour cycle in adult male Wistar rats...
  17. doi request reprint Effect of a high-fat diet on 24-h pattern of circulating levels of prolactin, luteinizing hormone, testosterone, corticosterone, thyroid-stimulating hormone and glucose, and pineal melatonin content, in rats
    Pilar Cano
    Departamento de Bioquimica y Biologia Molecular III, Facultad de Medicina, Universidad Complutense, Madrid, 28040, Spain
    Endocrine 33:118-25. 2008
    ..The amplitude of the nocturnal pineal melatonin peak decreased significantly in high-fat fed rats. The results underlie the significant effects that obesity has on circadian organization of hormone secretion...
  18. doi request reprint Melatonin effect on plasma adiponectin, leptin, insulin, glucose, triglycerides and cholesterol in normal and high fat-fed rats
    María J Ríos-Lugo
    Departamento de Bioquimica y Biologia Molecular III, Facultad de Medicina, Universidad Complutense, Madrid, Spain
    J Pineal Res 49:342-8. 2010
    ..The results indicate that melatonin counteracts some of the disrupting effects of diet-induced obesity in rats...
  19. ncbi request reprint Twenty-four-hour rhythms of mitogenic responses, lymphocyte subset populations and amino acid content in submaxillary lymph nodes of growing male rats subjected to calorie restriction
    Ana I Esquifino
    Departamento de Bioquimica y Biologia Molecular III, Facultad de Medicina, Universidad Complutense, 28040 Madrid, Spain
    J Neuroimmunol 156:66-73. 2004
    ..Availability of nutrients presumably affects the mechanisms that modulate the circadian variation of immune responsiveness in growing rats...
  20. ncbi request reprint 24-hour changes in circulating prolactin, follicle-stimulating hormone, luteinizing hormone, and testosterone in young male rats subjected to calorie restriction
    Fernando Chacon
    Departamento de Bioquimica y Biologia Molecular III, Facultad de Medicina, Universidad Complutense, Madrid, Spain
    Chronobiol Int 21:393-404. 2004
    ..Availability of nutrients presumably affects the mechanisms that modulate the circadian variation of the pituitary-gonadal axis in growing male rats...
  21. ncbi request reprint Differential responses of circulating prolactin, GH, and ACTH levels and distribution and activity of submaxillary lymph node lymphocytes to calorie restriction in male Lewis and Wistar rats
    Sara Lopez-Varela
    Departamento de Bioquimica y Biologia Molecular III, Facultad de Medicina, Universidad Complutense, Madrid, Spain
    Neuroimmunomodulation 11:247-54. 2004
    ..The aim of this study was to determine whether 66% calorie restriction (lipids and carbohydrates) differentially affects growing rats of the Wistar or Lewis strains...
  22. doi request reprint Discontinuous versus continuous drinking of ethanol in peripubertal rats: effect on 24-hour pattern of hypophyseal-gonadal axis activity and anterior pituitary oxidative stress
    Pilar Fernández-Mateos
    Department of Biochemistry and Molecular Biology III, Universidad Complutense, Madrid, Spain
    Neuroendocrinology 96:194-203. 2012
    ..This study therefore assesses, in peripubertal male rats, the effect of discontinuous as compared to chronic feeding of ethanol or control liquid diet...
  23. doi request reprint Effect of cadmium on 24-hour pattern in expression of redox enzyme and clock genes in rat medial basal hypothalamus
    Vanesa Jimenez-Ortega
    Departamento de Bioquimica y Biologia Molecular III, Facultad de Medicina, Universidad Complutense, Madrid, Spain
    Biometals 23:327-37. 2010
    ..The results are compatible with the view that a low amount of Cd given in tap water brought about significant changes in circadian expression of redox enzyme and clock genes in rat MBH...
  24. ncbi request reprint 24-Hour rhythm in gene expression of nitric oxide synthase and heme-peroxidase in anterior pituitary of ethanol-fed rats
    Vanesa Jimenez-Ortega
    Department of Biochemistry and Molecular Biology III, School of Medicine, Universidad Complutense de Madrid, Madrid 28040, Spain
    Neurosci Lett 425:69-72. 2007
    ..One of the mechanisms by which ethanol augments oxidative damage in the adenohypophysis may include overproduction of nitric oxide and carbon monoxide...
  25. ncbi request reprint Effect of aging on 24-hour changes in dopamine and serotonin turnover and amino acid and somatostatin contents of rat corpus striatum
    Ana I Esquifino
    Departamento de Bioquimica y Biologia Molecular III, Facultad de Medicina, Universidad Complutense, Madrid, Spain
    Neurosignals 11:336-44. 2002
    ..Some of the circadian modifications of motor function seen in aging rats could be related to the striatal transmitter changes reported herein...
  26. doi request reprint 24-Hour variation in gene expression of redox pathway enzymes in rat hypothalamus: effect of melatonin treatment
    Vanesa Jimenez-Ortega
    Department of Biochemistry and Molecular Biology III, School of Medicine, Universidad Complutense, Madrid, Spain
    Redox Rep 14:132-8. 2009
    ..e. gene expression of redox pathway enzymes) effect of melatonin on redox pathway in the hypothalamus is mainly exerted via down-regulation of pro-oxidant enzyme mRNAs...
  27. ncbi request reprint 24-hour changes in ACTH, corticosterone, growth hormone, and leptin levels in young male rats subjected to calorie restriction
    Fernando Chacon
    Departamento de Bioquimica y Biologia Molecular III, Facultad de Medicina, Universidad Complutense, Madrid, Spain
    Chronobiol Int 22:253-65. 2005
    ..The changes in the secretory pattern of hormones hereby reported may be part of the neuroendocrine and metabolic mechanisms evolved to maximize survival during periods of food shortage...
  28. doi request reprint Effect of aging on 24-hour pattern of stress hormones and leptin in rats
    Pilar Cano
    Departamento de Bioquimica y Biologia Molecular III, Facultad de Medicina, Universidad Complutense, Madrid, Spain
    Life Sci 83:142-8. 2008
    ..Likewise, plasma leptin correlated with plasma corticosterone only in young rats. These changes can be attributed to a disrupting effect of aging on the homeostatic mechanisms modulating HPA activity and leptin release...
  29. ncbi request reprint Effect of ethanol on 24-hour hormonal changes in peripubertal male rats
    Vanessa Jimenez
    Departamento de Bioquimica y Biologia Molecular III, Facultad de Medicina, Universidad Complutense, Avda Complutense s n, 28040 Madrid, Spain
    Alcohol 34:127-32. 2004
    ..Chronic ethanol administration presumably affects the endogenous clock that modulates the circadian variation of the pituitary-gonadal axis and thyrotropin release in growing male rats...
  30. doi request reprint Melatonin supplementation decreases prolactin synthesis and release in rat adenohypophysis: correlation with anterior pituitary redox state and circadian clock mechanisms
    Vanesa Jimenez-Ortega
    Department of Biochemistry and Molecular Biology III, Faculty of Medicine, Universidad Complutense, Madrid, Spain
    Chronobiol Int 29:1021-35. 2012
    ..The results indicate that under prolonged duration of a daily melatonin signal, rat anterior pituitary PRL synthesis and release are depressed, together with significant changes in the redox and circadian mechanisms controlling them...
  31. doi request reprint Effect of a high-fat diet on 24-hour pattern of circulating adipocytokines in rats
    Pilar Cano
    Departamento de Bioquimica y Biologia Molecular III, Facultad de Medicina, Universidad Complutense, Madrid, Spain
    Obesity (Silver Spring) 17:1866-71. 2009
    ....
  32. ncbi request reprint Cadmium-induced changes in Per 1 and Per 2 gene expression in rat hypothalamus and anterior pituitary: effect of melatonin
    Pilar Cano
    Department of Biochemistry and Molecular Biology III, School of Medicine, Universidad Complutense de Madrid, Madrid, Spain
    Toxicol Lett 172:131-6. 2007
    ..The results indicate that Cd administered chronically in the drinking water to rats affected expression of clock genes in the hypothalamic-pituitary unit, an effect prevented by melatonin...
  33. ncbi request reprint Daily changes of GABA and taurine concentrations in various hypothalamic areas are affected by chronic hyperprolactinemia
    Beatriz H Duvilanski
    Departamento de Bioquimica y Biologia Molecular III, Facultad de Medicina, Universidad Complutense, Madrid, Spain
    Chronobiol Int 20:271-84. 2003
    ..These data show that GABA and TAU content exhibit specific daily patterns in each hypothalamic region studied. PRL differentially affects the daily pattern of these amino acids in each hypothalamic region analyzed...
  34. ncbi request reprint Age-related changes in 24-hour rhythms of norepinephrine content and serotonin turnover in rat pineal gland: effect of melatonin treatment
    David Pazo
    Departamento de Bioquimica y Biologia Molecular III, Facultad de Medicina, Universidad de Buenos Aires, Buenos Aires, Argentina
    Neurosignals 11:81-7. 2002
    ..Impairment of pineal melatonin synthesizing capacity and intrapineal responses to melatonin may underlie pineal aging in rats...
  35. ncbi request reprint Effect of chronic ethanol feeding on 24-hour rhythms of mitogenic responses and lymphocyte subset populations in thymus and spleen of peripubertal male rats
    Vanessa Jimenez
    Departamento de Bioquimica y Biologia Molecular III, Facultad de Medicina, Universidad Complutense, Madrid, Spain
    Neuroimmunomodulation 12:357-65. 2005
    ..Chronic ethanol administration presumably affects the endogenous clock that modulates the circadian variation of immune responsiveness in growing rats...
  36. doi request reprint Melatonin normalizes clinical and biochemical parameters of mild inflammation in diet-induced metabolic syndrome in rats
    Pilar Cano Barquilla
    Department of Biochemistry and Molecular Biology III, Faculty of Medicine, Universidad Complutense, Madrid, Spain
    J Pineal Res 57:280-90. 2014
    ..The results indicate that melatonin is able to normalize the altered biochemical pro-inflammatory profile seen in rats fed with a high-fat diet...
  37. doi request reprint Effects of every-other-day feeding on prolactin regulatory mechanism in transgenic human growth hormone mice
    Vanesa Jimenez-Ortega
    Departamento de Bioquimica y Biologia Molecular III, Facultad de Medicina, Universidad Complutense, 28040 Madrid, Spain
    Exp Biol Med (Maywood) 233:434-8. 2008
    ..These parameters were not affected by the EOD feeding pattern. These data may suggest an autocrine or paracrine effect of dopamine at the hypophyseal level on prolactin secretion that is independent of the feeding pattern...
  38. pmc Cadmium-Induced Disruption in 24-h Expression of Clock and Redox Enzyme Genes in Rat Medial Basal Hypothalamus: Prevention by Melatonin
    Vanesa Jimenez-Ortega
    Departamento de Bioquimica y Biologia Molecular III, Universidad Complutense Facultad de Medicina, Spain
    Front Neurol 2:13. 2011
    ..The results indicate that the interfering effect of melatonin on the activity of a low dose of CdCl(2) on MBH clock and redox enzyme genes is mainly exerted at the level of redox enzyme gene expression...
  39. ncbi request reprint Effect of melatonin on in vitro gonadotropins and prolactin release from pituitary LHRH stimulated, and median eminence and on ovarian response to hCG in middle-aged female rats
    Elena Diaz
    Dpto Biologia Funcional, Área Fisiología, Facultad de Medicina, Universidad de Oviedo, Spain
    Neuro Endocrinol Lett 20:229-236. 1999
    ..We concluded that melatonin may have a physiological role in middle-aged rats since decreased in vitro basal FSH release and blunted LH and estradiol increase after stimuli...
  40. ncbi request reprint Effects of melatonin on 24-h rhythms of neuroendocrine and immune changes in Freund's adjuvant-induced arthritis
    Ana I Esquifino
    Departamento de Bioquimica y Biologia Molecular III, Facultad de Medicina, Universidad Complutense, Madrid, Spain
    Neuro Endocrinol Lett 20:163-166. 1999
    ..The changes are compatible with the values of ornithine descarboxylase activity...