J Sastre

Summary

Country: Spain

Publications

  1. doi request reprint Molecular diagnosis in allergy
    J Sastre
    Allergy Department, Fundacion Jimenez Diaz, Madrid, Spain
    Clin Exp Allergy 40:1442-60. 2010
  2. doi request reprint Occupational asthma due to tampico fiber from agave leaves
    S Quirce
    Hospital Universitario La Paz, Servicio de Alergia, P Castellana, 261, 28046 Madrid, Spain
    Allergy 63:943-5. 2008
  3. ncbi request reprint Changes in exhaled nitric oxide after inhalation challenge with occupational agents
    J Sastre
    Allergy Department, Fundación Jiménez Díaz and CIBER de Enfermedades Respiratorias CIBERES Madrid, Spain
    J Investig Allergol Clin Immunol 23:421-7. 2013
  4. doi request reprint How molecular diagnosis can change allergen-specific immunotherapy prescription in a complex pollen area
    J Sastre
    Allergy Department, Fundacion Jimenez Diaz, Madrid, Spain
    Allergy 67:709-11. 2012
  5. ncbi request reprint Local and systemic safety of intranasal corticosteroids
    J Sastre
    Servicio de Alergia, Fundacion Jimenez Diaz, Universidad Autonoma de Madrid, Madrid, Spain
    J Investig Allergol Clin Immunol 22:1-12. 2012
  6. doi request reprint Efficacy and safety of bilastine 20 mg compared with cetirizine 10 mg and placebo in the treatment of perennial allergic rhinitis
    Joaquin Sastre
    Allergy Department, Fundacion Jimenez Diaz, Madrid, Spain
    Curr Med Res Opin 28:121-30. 2012
  7. ncbi request reprint Mites in Madrid
    J Sastre
    Fundacion Jimenez Diaz, Servicio de Alergia, Madrid, Spain
    Allergy 57:58-9. 2002
  8. ncbi request reprint Increased body mass index does not lead to a worsening of asthma control in a large adult asthmatic population in Spain
    J Sastre
    Allergy Department, Fundación Jiménez Díaz Capio and CIBER de Enfermedades Respiratorias CIBERES Madrid, Spain
    J Investig Allergol Clin Immunol 20:551-5. 2010
  9. doi request reprint Airway response to chlorine inhalation (bleach) among cleaning workers with and without bronchial hyperresponsiveness
    Joaquin Sastre
    Allergy Department, Fundacion Jimenez Diaz Capio, CIBER de Enfermedades Respiratorias, Madrid, Spain
    Am J Ind Med 54:293-9. 2011
  10. doi request reprint Occupational asthma caused by triglycidyl isocyanurate
    Joaquin Sastre
    Allergy Department, Fundación Jiménez Díaz Capio and CIBER de Enfermedades Respiratorias CIBERES, Av Reyes Catolicos 2, 28040 Madrid, Spain
    Int Arch Occup Environ Health 84:547-9. 2011

Detail Information

Publications62

  1. doi request reprint Molecular diagnosis in allergy
    J Sastre
    Allergy Department, Fundacion Jimenez Diaz, Madrid, Spain
    Clin Exp Allergy 40:1442-60. 2010
    ..Nevertheless, all in vitro tests should be evaluated together with the clinical history, because allergen sensitization does not necessarily imply clinical responsiveness...
  2. doi request reprint Occupational asthma due to tampico fiber from agave leaves
    S Quirce
    Hospital Universitario La Paz, Servicio de Alergia, P Castellana, 261, 28046 Madrid, Spain
    Allergy 63:943-5. 2008
  3. ncbi request reprint Changes in exhaled nitric oxide after inhalation challenge with occupational agents
    J Sastre
    Allergy Department, Fundación Jiménez Díaz and CIBER de Enfermedades Respiratorias CIBERES Madrid, Spain
    J Investig Allergol Clin Immunol 23:421-7. 2013
    ..Materialandmethods: Workers with suspected occupational asthma were recruited to undergo SIC with occupational agents and subsequently FeNO testing at baseline and 24 hours...
  4. doi request reprint How molecular diagnosis can change allergen-specific immunotherapy prescription in a complex pollen area
    J Sastre
    Allergy Department, Fundacion Jimenez Diaz, Madrid, Spain
    Allergy 67:709-11. 2012
    ..The aim of this study was to determine whether molecular diagnosis (MD) may change indication and allergen prescription of SIT...
  5. ncbi request reprint Local and systemic safety of intranasal corticosteroids
    J Sastre
    Servicio de Alergia, Fundacion Jimenez Diaz, Universidad Autonoma de Madrid, Madrid, Spain
    J Investig Allergol Clin Immunol 22:1-12. 2012
    ....
  6. doi request reprint Efficacy and safety of bilastine 20 mg compared with cetirizine 10 mg and placebo in the treatment of perennial allergic rhinitis
    Joaquin Sastre
    Allergy Department, Fundacion Jimenez Diaz, Madrid, Spain
    Curr Med Res Opin 28:121-30. 2012
    ..The objective of this study was to demonstrate the efficacy and safety of bilastine in patients with perennial allergic rhinitis (PAR)...
  7. ncbi request reprint Mites in Madrid
    J Sastre
    Fundacion Jimenez Diaz, Servicio de Alergia, Madrid, Spain
    Allergy 57:58-9. 2002
  8. ncbi request reprint Increased body mass index does not lead to a worsening of asthma control in a large adult asthmatic population in Spain
    J Sastre
    Allergy Department, Fundación Jiménez Díaz Capio and CIBER de Enfermedades Respiratorias CIBERES Madrid, Spain
    J Investig Allergol Clin Immunol 20:551-5. 2010
    ..Data on the association between obesity and asthma control are conflicting. We performed an analysis to elucidate the association between body mass index (BMI) and asthma control in a large sample of asthmatics...
  9. doi request reprint Airway response to chlorine inhalation (bleach) among cleaning workers with and without bronchial hyperresponsiveness
    Joaquin Sastre
    Allergy Department, Fundacion Jimenez Diaz Capio, CIBER de Enfermedades Respiratorias, Madrid, Spain
    Am J Ind Med 54:293-9. 2011
    ..Symptoms of obstructive lung disease in domestic cleaning staff have been related to the use of bleach and other irritant cleaning products...
  10. doi request reprint Occupational asthma caused by triglycidyl isocyanurate
    Joaquin Sastre
    Allergy Department, Fundación Jiménez Díaz Capio and CIBER de Enfermedades Respiratorias CIBERES, Av Reyes Catolicos 2, 28040 Madrid, Spain
    Int Arch Occup Environ Health 84:547-9. 2011
    ....
  11. ncbi request reprint Immunotherapy: an option in the management of occupational asthma?
    Joaquin Sastre
    Fundacion Jimenez Diaz, Allergy Department, Universidad Autonoma de Madrid, Madrid, Spain
    Curr Opin Allergy Clin Immunol 6:96-100. 2006
    ..To review clinical data on immunotherapy applied to occupational asthma...
  12. ncbi request reprint IgG(4)-mediated allergic reaction to glargine insulin
    M F Madero
    Fundacion Jimenez Diaz, Servicio de Alergia, Av Reyes Catolicos 2, 28040 Madrid, Spain
    Allergy 61:1022-3. 2006
  13. ncbi request reprint Pathogenesis of occupational asthma
    J Sastre
    Servicio de Alergia, Fundacion Jimenez Diaz, Universidad Autonoma de Madrid, Madrid, Spain
    Eur Respir J 22:364-73. 2003
    ....
  14. ncbi request reprint Need for monitoring nonspecific bronchial hyperresponsiveness before and after isocyanate inhalation challenge
    Joaquin Sastre
    Fundacion Jimenez Diaz, Allergy Department, Madrid, Spain
    Chest 123:1276-9. 2003
    ..Specific and nonspecific bronchial responsiveness may decline or disappear after cessation of exposure in the workplace in patients with occupational asthma, leading to false-negative specific inhalation challenge (SIC) results...
  15. ncbi request reprint Double-blind study of tolerability and antibody production of unmodified and chemically modified allergen vaccines of Phleum pratense
    M Casanovas
    Laboratorios LETI, S L, Tres Cantos, Madrid, Spain
    Clin Exp Allergy 35:1377-83. 2005
    ..The physicochemical modification of allergen extracts provides a chance for administering higher doses of allergen vaccines...
  16. ncbi request reprint Bronchial responsiveness to bakery-derived allergens is strongly dependent on specific skin sensitivity
    S Quirce
    Allergy Department, Fundacion Jimenez Diaz, Madrid, Spain
    Allergy 61:1202-8. 2006
    ..Quantitative relationships between immunological reactivity, non-specific bronchial responsiveness and bronchial responsiveness to allergens have scarcely been investigated in occupational asthma...
  17. ncbi request reprint Allergenicity and cross-reactivity of Russian olive pollen (Eleagnus angustifolia)
    J Sastre
    Fundacion Jimenez Diaz, Servicio de Alergia, Universidad Autonoma de Madrid, Madrid, Spain
    Allergy 59:1181-6. 2004
    ..The purposes of this study were: to determine the prevalence of sensitization and immunochemical characterization of Eleagnus angustifolia pollen (Russian olive) that belongs to the family Eleagnaceae...
  18. ncbi request reprint Egg white proteins as inhalant allergens associated with baker's asthma
    C Escudero
    Fundacion Jimenez Diaz, Allergy Department, Madrid, Spain
    Allergy 58:616-20. 2003
    ..Bakery workers may develop IgE-mediated allergy to liquid and aerosolized hen's egg proteins that are commonly used in the baking and confectionery industries...
  19. doi request reprint Recombinant lipid transfer protein Tri a 14: a novel heat and proteolytic resistant tool for the diagnosis of baker's asthma
    A Palacin
    Unidad de Bioquimica, Departamento de Biotecnologia, E T S Ingenieros Agronomos, Madrid, Spain
    Clin Exp Allergy 39:1267-76. 2009
    ..Wheat lipid transfer protein (LTP) Tri a 14 is a major allergen associated with wheat allergy. No panel of wheat recombinant allergens for component-resolved diagnosis of baker's asthma is currently available...
  20. ncbi request reprint Occupational asthma caused by exposure to cyanoacrylate
    S Quirce
    , , Madrid, Spain
    Allergy 56:446-9. 2001
    ..CONCLUSION: Exposure to cyanoacrylate in these patients provoked not only variable airflow limitation and bronchial hyperresponsiveness, but also pronounced eosinophilia in sputum...
  21. ncbi request reprint Immunotherapy with a Phleum pratense allergen extract induces an immune response to a grass-mix allergen extract
    C Martinez-Cocera
    Allergy Department, Hospital Clinico Universitario San Carlos, Madrid, Spain
    J Investig Allergol Clin Immunol 20:13-9. 2010
    ..Grass pollen allergy is one of the most common allergies worldwide, and patients often show sensitization to an array of phylogenetically related species...
  22. ncbi request reprint Rapid release of Ole e 1 from olive pollen using different solvents
    J Carnes
    C B F LETI, S A, Research and Development Department, Tres Cantos, Madrid, Spain
    Allergy 57:798-804. 2002
    ..Solubility is an important characteristic of allergenic molecules. The aim of this study was to investigate the solubility of Ole e 1, a major allergen of Olea europaea, using different solvents...
  23. ncbi request reprint Occupational asthma due to piperazine citrate
    S Quirce
    Allergy Department, Fundacion Jimenez Diaz, Madrid, Spain
    J Investig Allergol Clin Immunol 16:138-9. 2006
    ..Piperazine is a secondary heterocyclic amine that may give rise to occupational asthma of uncertain mechanism...
  24. ncbi request reprint IgE reactivity to latex allergens among sensitized healthcare workers before and after immunotherapy with latex
    J Sastre
    Fundacion Jimenez Diaz, Servicio de Alergia, Madrid, Spain
    Allergy 61:206-10. 2006
    ..New IgE sensitizations to proteins in allergen extracts have been shown to occur during allergen-specific immunotherapy (IT)...
  25. ncbi request reprint Increased prostaglandin E2 levels in the airway of patients with eosinophilic bronchitis
    B Sastre
    Immunology Department Fundación Jiménez Díaz Capio, CIBERES ISCIII, Madrid, Spain
    Allergy 63:58-66. 2008
    ....
  26. ncbi request reprint Occupational asthma in industry
    M Fernández-Nieto
    Allergy Department, Jimenez Diaz Foundation, Madrid, Spain
    Allergol Immunopathol (Madr) 34:212-23. 2006
    ..Occupational asthma remains a minority diagnosis among occupational diseases in general. Adequate personnel training and the creation of diagnostic centers may help to ensure correct and rapid detection of this disease...
  27. ncbi request reprint Chicken serum albumin (Gal d 5*) is a partially heat-labile inhalant and food allergen implicated in the bird-egg syndrome
    S Quirce
    Allergy Department, Fundacion Jimenez Diaz, Av Reyes Catolicos 2, Madrid, Spain
    Allergy 56:754-62. 2001
    ..The heat resistance of chicken albumin and the possible cross-reactivity with conalbumin were also investigated...
  28. ncbi request reprint Occupational asthma and rhinitis caused by eugenol in a hairdresser
    S Quirce
    Fundacion Jimenez Diaz, Servicio de Alergia, Av Reyes Católicos, 2, 28040 Madrid, Spain
    Allergy 63:137-8. 2008
  29. ncbi request reprint Occupational asthma due to spores of Pleurotus ostreatus
    A Vereda
    Servicio de Alergologia, Fundacion Jimenez Diaz, Avda Reyes Catolicos, 2 28040 Madrid, Spain
    Allergy 62:211-2. 2007
  30. ncbi request reprint Lack of allergic cross-reactivity to cephalosporins among patients allergic to penicillins
    A Novalbos
    Servicio de Alergia, , , , 28040 Madrid, Spain
    Clin Exp Allergy 31:438-43. 2001
    ....
  31. ncbi request reprint Circulating tumor cells in locally advanced breast cancer
    J A Garcia-Saenz
    Clinico San Carlos Universitary Hospital, Madrid, Spain
    J Clin Oncol 27:e22159. 2009
    ....
  32. ncbi request reprint Is regorafenib providing clinically meaningful benefits to pretreated patients with metastatic colorectal cancer?
    P Garcia-Alfonso
    Medical Oncology Department, Gregorio Marañón University Hospital Center Affiliated to the Red Tematica de Investigacion Cooperativa en Cancer RTICC, Instituto Carlos III, Spanish Ministry of Science and Innovation, Madrid, Spain
    Clin Transl Oncol 18:1072-1081. 2016
    ..Additionally, the magnitude of the clinical benefit provided by regorafenib to these patients has been explored and whether there are poorer outcomes in certain subpopulations...
  33. ncbi request reprint Cetuximab and capecitabine as first-line treatment for elderly patients (pts) with metastatic colorectal cancer (mCRC): Preliminary results of TTD trial
    C Gravalos
    Hospital 12 de Octubre, Madrid, Spain Hospital Marqués Valdecilla, Santander, Spain Hospital General, Alicante, Spain Hospital Clinico Universitario San Carlos, Madrid, Spain Hospital Santa Creu i Sant Pau, Barcelona, Spain Complejo Hospitalario Juan Canalejo, La Coruna, Spain Hospital Regional Universitario Carlos Haya, Malaga, Spain Institute of Oncology Hospital Germans Trias I Pujol, Badalona, Spain Hospital Clinico Universitario San Carlos, Madrid, Spain Hospital Reina Sofía, Cordoba, Spain
    J Clin Oncol 26:15027. 2008
    ..Now we are doing this trial to determine the efficacy and tolerance of Cetuximab in combination with Capecitabine...
  34. ncbi request reprint Hypersensitivity pneumonitis caused by triglycidyl isocyanurate
    S Quirce
    Allergy Department, Fundacion Jimenez Diaz, Av Reyes Catolicos 2, 28040 Madrid, Spain
    Allergy 59:1128. 2004
  35. ncbi request reprint Hypersensitivity pneumonitis caused by domestic exposure to molds
    A Enríquez-Matas
    Fundacion Jimenez Diaz, Madrid, Spain
    J Investig Allergol Clin Immunol 17:126-7. 2007
  36. doi request reprint An odorant-binding protein as a new allergen from Siberian hamster (Phodopus sungorus)
    J A Torres
    Department of Allergy, Fundacion Jimenez Diaz, Av Reyes Catolicos 2, Madrid, Spain
    Int Arch Allergy Immunol 157:109-12. 2012
    ..The 3 bands likely correspond to isoforms of a single allergen...
  37. ncbi request reprint Isolation, cloning and allergenic reactivity of natural profilin Cit s 2, a major orange allergen
    G Lopez-Torrejon
    Unidad de Bioquimica, Departamento de Biotecnologia, E T S Ingenieros Agronomos, Madrid, Spain
    Allergy 60:1424-9. 2005
    ..However, its relevant allergenic components are virtually unknown. Profilin is a well-defined minor plant panallergen, showing prevalences around 30% in fruits and vegetables...
  38. ncbi request reprint Sorafenib and bevacizumab combination targeted therapy in advanced neuroendocrine tumor: A phase II study of the Spanish Neuroendocrine Tumor Group (GETNE0801)
    D E Castellano
    Hospital Universitario 12 de Octubre, Madrid, Spain Vall d Hebron University Hospital, Barcelona, Spain Institut Catala d Oncologia, Barcelona, Spain Hospital Clínico San Carlos, Madrid, Spain Hospital Miguel Servet, Zaragoza, Spain Canarias, Tenerife, Spain Hospital Universitario Virgen del Rocío Instituto de Biomedicina de Sevilla IBIS, Sevilla, Spain University Hospital Germans Trias i Pujol ICO, Barcelona, Spain Hospital Universitario Virgen de la Victoria, Malaga, Spain START Madrid, Centro Integral Oncologico Clara Campal, Madrid, Spain
    J Clin Oncol 29:4113. 2011
    ..S+B combination has shown manageable toxicity in phase I trials in solid tumors. The aim of this study was to evaluate the efficacy and toxicity of the STI's combination in NETs...
  39. ncbi request reprint Oral latex glove allergy
    C De Castro
    Allergy Department, Fundacion Jimenez Diaz, Avenue Reyes Católicos 2, 28040 Madrid, Spain
    Allergy 57:462. 2002
  40. ncbi request reprint Allergenicity and immunochemical characterization of six varieties of Olea europaea
    J Carnés Sánchez
    C B F LETI, S A Research and Development Laboratories, Madrid, Spain
    Allergy 57:313-8. 2002
    ..The objective of this study was to investigate the antigenic and allergenic composition of six different O. europaea varieties collected in southern Spain...
  41. doi request reprint Noninvasive methods for assessment of airway inflammation in occupational settings
    S Quirce
    Department of Allergy, Hospital La Paz, Madrid, Spain
    Allergy 65:445-58. 2010
    ..Key messages and suggestions on the use of noninvasive methods for assessment of airway inflammation in the investigation and diagnosis of occupational airway diseases are issued...
  42. doi request reprint Irinotecan-cetuximab-bevacizumab as a salvage treatment in heavily pretreated metastatic colorectal cancer patients: a retrospective observational study
    J Feliu Batlle
    Medical Oncology Department, Hospital Universitario La Paz, Madrid, Spain
    Chemotherapy 57:138-44. 2011
    ..The objective was to evaluate the efficacy of irinotecan-cetuximab-bevacizumab in combination as a salvage treatment for heavily pretreated metastatic colorectal cancer patients...
  43. ncbi request reprint Progressive loss of antiemetic efficacy during subsequent courses of chemotherapy
    M Martin
    Servicio de Oncologia Medica, Hospital Universitario San Carlos, Madrid, Spain
    Eur J Cancer 28:430-2. 1992
    ..These data, together with other from the literature, should be taken into consideration when reviewing the overall results of current antiemetic trials, which usually only mention the results obtained in the first course of chemotherapy...
  44. ncbi request reprint Anaphylaxis caused by cauliflower
    E Hernandez
    Fundacion Jimenez Diaz, Servicio de Alergia, Madrid Spain
    J Investig Allergol Clin Immunol 15:158-9. 2005
    ..Cauliflower is a vegetable belonging to the family Cruciferae, genus Brassica, var. Botrytis...
  45. ncbi request reprint Occupational asthma due to the inhalation of cauliflower and cabbage vapors
    S Quirce
    Fundación Jiménez Díaz Servicio de Alergia Av Reyes Católicos, 2 28040 Madrid Spain
    Allergy 60:969-70. 2005
  46. ncbi request reprint Pharmacogenetic approach for capecitabine or 5-fluorouracil (5FU) selection to be combined with oxaliplatin as first-line chemotherapy in advanced colorectal cancer
    E Martinez-Balibrea
    Hospital Germans Trias i Pujol ICO Badalona, Badalona, Spain Hospital Reina Sofía, Cordoba, Spain Hospital Clínico San Carlos, Madrid, Spain Hospital Universitari la Fe, Valencia, Spain Hospital Morales Meseguer, Murcia, Spain Hospital Virgen de los Lirios, Alicancte, Spain Institut Català d Oncologia IDIBELL, L Hospitalet de Llobregat, Spain
    J Clin Oncol 26:4132. 2008
    ..The aim of this work was to study genetic polymorphisms and their role in tailoring fluroropyrimidine/oxaliplatin treatment in metastatic colorectal cancer (mCRC)...
  47. doi request reprint Occupational hypersensitivity pneumonitis: an EAACI position paper
    S Quirce
    Department of Allergy, Hospital La Paz Institute for Health Research IdiPAZ and CIBER de Enfermedades Respiratorias CIBERES, Madrid, Spain
    Allergy 71:765-79. 2016
    ..The cornerstone of treatment is early removal from exposure to the eliciting antigen, although the disease may show an adverse outcome even after avoidance of exposure to the causal agent. ..
  48. ncbi request reprint Successful rectal cancer local recurrence radiofrequency ablation
    C Bueno Muiño
    Servicio de Oncologia Medica, Hospital Universitario San Carlos, Madrid, Spain
    Clin Transl Oncol 10:300-2. 2008
    ..A local rectal cancer recurrence radiofrequency ablation is reported. PET scan confirmed the recurrence, defined the target volume and assessed the success of the local therapy...
  49. doi request reprint Recommendations and expert opinion on the treatment of locally advanced rectal cancer in Spain
    C Gravalos
    Hospital 12 de Octubre, Madrid, Spain
    Clin Transl Oncol 13:862-8. 2011
    ..Capecitabine, after showing a trend in improved downstaging in neoadjuvant stratum and the convenience of its oral administration, represents an alternative to 5-FU as perioperative treatment of LARC...
  50. ncbi request reprint Urticaria caused by cola drink
    M Fernández-Nieto
    Fundacion Jimenez Diaz, Allergy Department, Av Reyes Católicos, 2, 28040 Madrid, Spain
    Allergy 57:967-8. 2002
  51. doi request reprint First-line single-agent cetuximab in elderly patients with metastatic colorectal cancer. A phase II clinical and molecular study of the Spanish group for digestive tumor therapy (TTD)
    J Sastre
    HC San Carlos, Madrid, Center affíliated to the Red Temática de Investigación Cooperativa RD06 0020 0021, Instituto Carlos III, Spanish Ministry of Science and Innovation, Spain
    Crit Rev Oncol Hematol 77:78-84. 2011
    ..to evaluate the efficacy and safety of first-line single-agent cetuximab in fit elderly patients with metastatic colorectal cancer, as well as potential molecular predictive factors for efficacy...
  52. ncbi request reprint Immunological studies in a case of hydrochlorothiazide-induced pulmonary edema
    A Vereda
    Fundacion Jimenez Diaz, Servicio de Alergia, Universidad Autonoma de Madrid, Spain
    J Investig Allergol Clin Immunol 15:297-8. 2005
    ..Immunological studies including lymphocyte stimulation test with HCT and measurement of specific IgG and IgE to HCT elicited negative results. The pathogenesis of this type of reaction remains to be elucidated...
  53. ncbi request reprint Evaluation of the efficacy and the safety of lanreotide autogel 120 mg on tumor growth stabilization in patients with progressive neuroendocrine tumors (NETs) who are not eligible to surgery or chemotherapy
    M Martin-Richard
    Hospital de Sant Pau, Barcelona, Spain Hospital Miguel Servet, Zaragoza, Spain Hospital Clínic, Barcelona, Spain Hospital Universitario 12 de Octubre, Madrid, Spain Hospital Universitario, Salamanca, Spain Hospital Universitario de la Princesa, Madrid, Spain Hospital Ramon y Cajal, Madrid, Spain University Hospital Marqués de Valdecilla, Santander, Spain Hospital de Sagunto, Sagunto, Spain C H Juan Canalejo, A Coruna, Spain H Virgen de los Lirios, Alicante, Spain H de Basurto, Basurto, Spain Hospital Clínico San Carlos, Madrid, Spain H de la Candelaria, Canarias, Spain Hospital de Sabadell, Corporacio Sanitaria Parc Tauli, Sabadell, Spain La Fe University Hospital, Valencia, Spain H General Universitario, Alicante, Spain Ipsen, Barcelona, Spain Medical Oncology Alicante University Hospital, Alicante, Spain
    J Clin Oncol 29:e14660. 2011
    ..We undertook a phase II trial (NCT0032646) to evaluate the efficacy of lanreotide Autogel 120mg on tumour growth stabilisation in patients with documented progressive NETs...
  54. ncbi request reprint PAZONET: A phase II trial of pazopanib in patients with metastatic neuroendocrine tumors (NETs) who may have previously received antiangiogenic or mTOR treatment
    J Capdevila
    Vall d Hebron University Hospital, Barcelona, Spain IDIBELL, Institut Català d Oncologia L Hospitalet, Barcelona, Spain Hospital Universitario 12 de Octubre, Madrid, Spain Hospital Clínico San Carlos, Madrid, Spain Hospital Universitario Virgen del Rocío Instituto de Biomedicina de Sevilla IBIS, Sevilla, Spain Hospital Universitario Virgen de la Victoria, Malaga, Spain START Madrid, Centro Integral Oncologico Clara Campal, Madrid, Spain Hospital Clinico Universitario Lozano Blesa, Zaragoza, Spain Hospital Universitario Son Espases, Mallorca, Spain Hospital Ramon y Cajal, Madrid, Spain
    J Clin Oncol 29:TPS171. 2011
    ..Previous activity of pazopanib in advanced gastroenteropancreatic NETs has been reported (Phan et al. ASCO 2010). No data is available of the activity of pazopanib after tumor progression to prior anti-VEGF or mTOR treatment...
  55. ncbi request reprint Effectiveness and safety of aflibercept for metastatic colorectal cancer: retrospective review within an early access program in Spain
    J Feliu
    Medical Oncology Department, Hospital Universitario La Paz, Paseo de la Castellana, 261, 28046, Madrid, Spain
    Clin Transl Oncol . 2016
    ..The use of aflibercept outside the clinical trial framework needs to be further assessed in terms of effectiveness and tolerability...
  56. pmc Clinical management of regorafenib in the treatment of patients with advanced colorectal cancer
    J Sastre
    Medical Oncology Department, Clinic San Carlos University Hospital Center Affiliated with the Red Tematica de Investigacion Cooperativa en Cancer, Instituto Carlos III, Spanish Ministry of Science and Innovation, Calle Profesor Martín Lagos, S N, 28040, Madrid, Spain
    Clin Transl Oncol 16:942-53. 2014
    ..This review addresses practical aspects of its use, such as dosing, patient monitoring, and management of the most common regorafenib-related AEs...
  57. doi request reprint Ebastine in allergic rhinitis and chronic idiopathic urticaria
    J Sastre
    Fundacion Jimenez Diaz, Allergy Service, CIBERES Inst Salud Carlos III, Madrid, Spain
    Allergy 63:1-20. 2008
    ..In addition to the regular tablet formulation, ebastine is available as a FDT, providing a treatment option that is particularly convenient for patients...
  58. ncbi request reprint Capecitabine (Xeloda) in combination with oxaliplatin: a phase I, dose-escalation study in patients with advanced or metastatic solid tumors
    E Diaz-Rubio
    Department of Oncology, Hospital Clinico Universitario San Carlos, Madrid, Spain
    Ann Oncol 13:558-65. 2002
    ..v. oxaliplatin. Secondary objectives included evaluation of the safety profile and antitumor activity...
  59. ncbi request reprint Effects of acute infusion of erythropoietin on paradoxical responses of growth hormone to thyrotropin-releasing hormone in acromegalic patients
    J J Diez
    Department of Endocrinology, Hospital La Paz, Madrid, Spain
    Eur J Endocrinol 143:203-11. 2000
    ..v. infusion of recombinant human erythropoietin (rhEPO) on the responses of growth hormone (GH), prolactin (PRL) and thyrotropin (TSH) to thyrotropin-releasing hormone (TRH) stimulation in acromegalic patients...
  60. ncbi request reprint Economic assessment of capecitabine/cisplatin versus 5-FU/cisplatin regimens in adjuvant treatment of advanced gastric cancer in Spain
    M Safont
    Hospital General Universitario de Valencia, Valencia, Spain Universitat de Barcelona, Barcelona, Spain BCN Health Economics and Outcomes Research, Barcelona, Spain Hospital Clínico San Carlos, Madrid, Spain Hospital del Mar, Barcelona, Spain Hospital Universitario Reina Sofía, Madrid, Spain C H Orense, Orense, Spain Roche Pharma, Madrid, Spain
    J Clin Oncol 26:15549. 2008
    ..6 months for XP versus 5.0 for FP) and response rates. An economic assessment was conducted in Spain to compare the costs of the two therapies taking into account unit costs and medical resource consumption for year 2007...
  61. pmc Clinical guideline SEOM: hepatocellular carcinoma
    J Sastre
    Medical Oncology Department, Hospital Universitario Clinico San Carlos, Prof Martin Lagos, S N, 28040, Madrid, Spain
    Clin Transl Oncol 17:988-95. 2015
    ..Surgical interventions remain as the only curative procedures but both local and systemic approaches may increase survival and should be offered to patients without contraindications. ..
  62. doi request reprint Circulating tumor cells in colorectal cancer: correlation with clinical and pathological variables
    J Sastre
    Department of Medical Oncology, Hospital Clinico San Carlos de Madrid, Madrid, Spain
    Ann Oncol 19:935-8. 2008
    ..Few data have been published concerning the role of CTCs detection by this method in colorectal cancer. The aim of this study was to correlate the presence of CTCs with the commonest clinical and morphological variables...