A Saiz

Summary

Country: Spain

Publications

  1. ncbi request reprint CD34+ selected autologous peripheral blood stem cell transplantation for multiple sclerosis: report of toxicity and treatment results at one year of follow-up in 15 patients
    Enric Carreras
    BMT Unit, Hospital Clinic, Villarroel 170, 08036 Barcelona, Spain
    Haematologica 88:306-14. 2003
  2. pmc Influence of timing on CSF tests value for Creutzfeldt-Jakob disease diagnosis
    Pascual Sanchez-Juan
    Department of Epidemiology and Biostatistics, Erasmus University Medical Center, 3000 DR Rotterdam, The Netherlands
    J Neurol 254:901-6. 2007
  3. doi request reprint Limbic encephalitis: an expanding concept
    Francesc Graus
    Neurology 70:500-1. 2008
  4. doi request reprint Therapeutic compliance of first line disease-modifying therapies in patients with multiple sclerosis. COMPLIANCE Study
    A Saiz
    Servicio de Neurologia, Hospital Clinic i Provincial de Barcelona, Universitat de Barcelona e Institut d́Investigació August Pi i Sunyer IDIBAPS, Barcelona, España Electronic address
    Neurologia 30:214-22. 2015
  5. pmc The multiple sclerosis visual pathway cohort: understanding neurodegeneration in MS
    Elena H Martínez-Lapiscina
    Center of Neuroimmunology, Institut d investigacions Biomèdiques August Pi I Sunyer IDIBAPS Hospital Clinic of Barcelona, Casanova 145, Planta 3a, 08036 Barcelona, Spain
    BMC Res Notes 7:910. 2014
  6. pmc Influence of corpus callosum damage on cognition and physical disability in multiple sclerosis: a multimodal study
    Sara Llufriu
    Center for Neuroimmunology, Service of Neurology, Hospital Clinic and Institut d Investigacions Biomediques August Pi i Sunyer IDIBAPS, Barcelona, Spain
    PLoS ONE 7:e37167. 2012
  7. pmc An optimized immunohistochemistry technique improves NMO-IgG detection: study comparison with cell-based assays
    Romana Hoftberger
    Service of Neurology, Hospital Clinic, Universitat de Barcelona and Institut d Investigació Biomèdica August Pi i Sunyer IDIBAPS, Barcelona, Spain Institute of Neurology, Medical University of Vienna, Vienna, Austria
    PLoS ONE 8:e79083. 2013
  8. pmc Cerebrospinal fluid biomarkers in human genetic transmissible spongiform encephalopathies
    Anna Ladogana
    Department of Cellular Biology and Neurosciences, Instituto Superiore di Sanita, Viale Regina Elena 299, 00161 Rome, Italy
    J Neurol 256:1620-8. 2009
  9. ncbi request reprint [Clinical outcome 6 years after autologous hematopoietic stem cell transplantation in multiple sclerosis]
    A Saiz
    Servicio de Neurologia, Hematología Hospital Clínic, Institut d Investigacio Biomedica August Pi i Sunyer IDIBAPS, Universitat de Barcelona, Barcelona
    Neurologia 23:405-7. 2008
  10. ncbi request reprint The impact of the introduction of the 14-3-3 protein assay in the surveillance of sporadic Creutzfeldt-Jakob disease in Catalonia
    A Saiz
    Service of Neurology, Hospital Clinic, Barcelona, Spain
    J Neurol 248:592-4. 2001

Detail Information

Publications68

  1. ncbi request reprint CD34+ selected autologous peripheral blood stem cell transplantation for multiple sclerosis: report of toxicity and treatment results at one year of follow-up in 15 patients
    Enric Carreras
    BMT Unit, Hospital Clinic, Villarroel 170, 08036 Barcelona, Spain
    Haematologica 88:306-14. 2003
    ..We report the results of a phase II trial to evaluate feasibility and toxicity of CD34+ selected ASCT (CD34+/ASCT) and treatment results at one year of follow-up...
  2. pmc Influence of timing on CSF tests value for Creutzfeldt-Jakob disease diagnosis
    Pascual Sanchez-Juan
    Department of Epidemiology and Biostatistics, Erasmus University Medical Center, 3000 DR Rotterdam, The Netherlands
    J Neurol 254:901-6. 2007
    ..The analysis of markers in the cerebrospinal fluid (CSF) is useful in the diagnosis of sporadic Creutzfeldt-Jakob disease (sCJD). However, the time at which the study of these markers is most sensitive remains controversal...
  3. doi request reprint Limbic encephalitis: an expanding concept
    Francesc Graus
    Neurology 70:500-1. 2008
  4. doi request reprint Therapeutic compliance of first line disease-modifying therapies in patients with multiple sclerosis. COMPLIANCE Study
    A Saiz
    Servicio de Neurologia, Hospital Clinic i Provincial de Barcelona, Universitat de Barcelona e Institut d́Investigació August Pi i Sunyer IDIBAPS, Barcelona, España Electronic address
    Neurologia 30:214-22. 2015
    ..We assessed compliance, the reasons for non-compliance, treatment satisfaction, and quality of life (QoL) of patients treated with first-line therapies...
  5. pmc The multiple sclerosis visual pathway cohort: understanding neurodegeneration in MS
    Elena H Martínez-Lapiscina
    Center of Neuroimmunology, Institut d investigacions Biomèdiques August Pi I Sunyer IDIBAPS Hospital Clinic of Barcelona, Casanova 145, Planta 3a, 08036 Barcelona, Spain
    BMC Res Notes 7:910. 2014
    ..The latter determines the prognosis of this disease. MS is the main cause of non-traumatic disability in middle-aged populations...
  6. pmc Influence of corpus callosum damage on cognition and physical disability in multiple sclerosis: a multimodal study
    Sara Llufriu
    Center for Neuroimmunology, Service of Neurology, Hospital Clinic and Institut d Investigacions Biomediques August Pi i Sunyer IDIBAPS, Barcelona, Spain
    PLoS ONE 7:e37167. 2012
    ..Corpus callosum (CC) is a common target for multiple sclerosis (MS) pathology. We investigated the influence of CC damage on physical disability and cognitive dysfunction using a multimodal approach...
  7. pmc An optimized immunohistochemistry technique improves NMO-IgG detection: study comparison with cell-based assays
    Romana Hoftberger
    Service of Neurology, Hospital Clinic, Universitat de Barcelona and Institut d Investigació Biomèdica August Pi i Sunyer IDIBAPS, Barcelona, Spain Institute of Neurology, Medical University of Vienna, Vienna, Austria
    PLoS ONE 8:e79083. 2013
    ..The optimized immunohistochemistry proves to be as sensitive and specific as the cell-based assays. This assay extends the available tools for NMO-IgG/aquaporin-4-antibody detection. ..
  8. pmc Cerebrospinal fluid biomarkers in human genetic transmissible spongiform encephalopathies
    Anna Ladogana
    Department of Cellular Biology and Neurosciences, Instituto Superiore di Sanita, Viale Regina Elena 299, 00161 Rome, Italy
    J Neurol 256:1620-8. 2009
    ..Disease duration and codon 129 genotype influence the findings in a different way than in sporadic CJD...
  9. ncbi request reprint [Clinical outcome 6 years after autologous hematopoietic stem cell transplantation in multiple sclerosis]
    A Saiz
    Servicio de Neurologia, Hematología Hospital Clínic, Institut d Investigacio Biomedica August Pi i Sunyer IDIBAPS, Universitat de Barcelona, Barcelona
    Neurologia 23:405-7. 2008
    ..We describe the clinical outcome of 14 patients included in a protocol of AHSCT after a median follow-up period of 6 years...
  10. ncbi request reprint The impact of the introduction of the 14-3-3 protein assay in the surveillance of sporadic Creutzfeldt-Jakob disease in Catalonia
    A Saiz
    Service of Neurology, Hospital Clinic, Barcelona, Spain
    J Neurol 248:592-4. 2001
    ..Our findings suggest an improvement of case ascertainment in part due to the introduction of the 14-3-3 assay in the surveillance system...
  11. ncbi request reprint Revised diagnostic criteria for neuromyelitis optica (NMO). Application in a series of suspected patients
    Albert Saiz
    Service of Neurology, Hospital Clinic and Institut d Investigació Biomèdica August Pi i Sunyer IDIBAPS, University of Barcelona, Villarroel 170, Barcelona, 08036 Spain
    J Neurol 254:1233-7. 2007
    ..25%; 87.5% vs. 62.5; 83.3% vs. 75%), but slightly lower sensitivity (87.5% vs. 93.7%). Our study confirms NMO-IgG as a highly specific marker of NMO, and the usefulness of the revised diagnostic criteria in predicting a diagnosis of NMO...
  12. ncbi request reprint SOX1 antibodies are markers of paraneoplastic Lambert-Eaton myasthenic syndrome
    L Sabater
    Service of Neurology, Hospital Clinic, Universitat de Barcelona, and Institut d Investigació Biomèdica August Pi i Sunyer, Barcelona 08036, Spain
    Neurology 70:924-8. 2008
    ..This study was undertaken to identify the antigen recognized by AGNA and to confirm the association with paraneoplastic LEMS in a larger series...
  13. ncbi request reprint MRI and CSF oligoclonal bands after autologous hematopoietic stem cell transplantation in MS
    A Saiz
    Services of Neurology, , , University of Barcelona, Spain
    Neurology 56:1084-9. 2001
    ....
  14. pmc Neuronal surface antigen antibodies in limbic encephalitis: clinical-immunologic associations
    F Graus
    Servei de Neurologia, Hospital Clinic and Institut d Investigació Biomèdica August Pi i Sunyer, Barcelona, Spain
    Neurology 71:930-6. 2008
    ..To report the frequency and type of antibodies against neuronal surface antigens (NSA-ab) in limbic encephalitis (LE)...
  15. ncbi request reprint Effect of glatiramer acetate (Copaxone) on the immunophenotypic and cytokine profile and BDNF production in multiple sclerosis: a longitudinal study
    Y Blanco
    Service of Neurology, Hospital Clinic, Universitat de Barcelona, Villarroel 170, 08036 Barcelona, Spain
    Neurosci Lett 406:270-5. 2006
    ....
  16. ncbi request reprint Clinical and MRI outcome after autologous hematopoietic stem cell transplantation in MS
    A Saiz
    Services of Neurology, Hospital Clinic, Institut d Investigacio Biomedica August Pi i Sunyer IDIBAPS, University of Barcelona, Spain
    Neurology 62:282-4. 2004
    ..The mean change in T2 lesion volume from baseline to the third year was -20.2% and that of the corpus callosum area was -12.7%; 50% of this reduction was seen during the first year...
  17. ncbi request reprint No association of the Val66Met polymorphism of brain-derived neurotrophic factor (BDNF) to multiple sclerosis
    Y Blanco
    Service of Neurology, Hospital Clinic, Universitat de Barcelona, Villarroel 170, 08036 Barcelona, Spain
    Neurosci Lett 396:217-9. 2006
    ..Moreover, we did not observe, in a subgroup of 12 MS patients, that the methionine substitution at position 66 in the prodomain had negative impact in the capacity to produce BDNF by peripheral blood mononuclear cells (PBMC)...
  18. doi request reprint Spanish consensus on the use of natalizumab (Tysabri®)-2013
    O Fernandez
    Instituto de Neurociencias clínicas, Servicio de Neurologia, Hospital Regional Universitario Carlos Haya, Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud, Malaga, España Electronic address
    Neurologia 30:302-14. 2015
    ....
  19. ncbi request reprint [Clinical spectrum associated with aquaporin-4 antibodies (NMO-IgG)]
    Y Blanco
    Servei de Neurologia, Hospital Clinic, Universitat de Barcelona e Institut d Investigació August Pi i Sunyer IDIBAPS, Barcelona, Espana
    Neurologia 25:5-12. 2010
    ....
  20. ncbi request reprint Value of Hu antibody determinations in the follow-up of paraneoplastic neurologic syndromes
    A Lladó
    Service of Neurology, Hospital Clinic, Universitat de Barcelona, and Institut d Investigació Biomèdica August Pi i Sunyer IDIBAPS, Barcelona Spain
    Neurology 63:1947-9. 2004
    ..No correlation was observed between Hu-Ab titers and neurologic outcome, tumor evolution, or type of treatment. Serial Hu-Ab determinations are not useful for monitoring the clinical outcome of patients with PNS...
  21. pmc Anti-glial nuclear antibody: marker of lung cancer-related paraneoplastic neurological syndromes
    F Graus
    Service of Neurology, Hospital Clinic, Universitat de Barcelona, and Institut d Investigació Biomèdica August Pi i Sunyer IDIBAPS, Villarroel 170, Barcelona 08036, Spain
    J Neuroimmunol 165:166-71. 2005
    ..0006). We conclude that the recognition of AGNA is helpful since this antibody is found in PNS associated with SCLC, particularly LEMS, in which other onconeural antibodies are absent...
  22. ncbi request reprint Spanish consensus on the use of natalizumab (Tysabri(®))--2011
    O Fernandez
    Servicio de Neurologia, Instituto de Neurociencias clínicas, Hospital Regional Universitario Carlos Haya, IMABIS, Malaga, Spain
    Neurologia 27:432-41. 2012
    ..The aim of this article is to provide a consensus view on the assessment and stratification of these risks, and to improve the management of natalizumab-treated patients...
  23. pmc Protein kinase Cgamma autoimmunity in paraneoplastic cerebellar degeneration and non-small-cell lung cancer
    L Sabater
    Service of Neurology, Hospital Clinic, and Institut d Investigació Biomèdica August Pi i Sunyer, Barcelona, Spain
    J Neurol Neurosurg Psychiatry 77:1359-62. 2006
    ..The clinical and immunological profiles of patients with paraneoplastic cerebellar degeneration (PCD) and non-small-cell lung cancer (NSCLC) are not well known...
  24. ncbi request reprint 14-3-3 protein in the CSF as prognostic marker in early multiple sclerosis
    A Martinez-Yelamos
    Service of Neurology, Ciutat Sanitaria Universitaria de Bellvitge, L Hospitalet, Spain
    Neurology 57:722-4. 2001
    ..8; 95% CI 2.86 to 76.8). The detection of the 14-3-3 protein in the CSF at the first neurologic event suggestive of MS may be a useful predictor of short-term evolution...
  25. ncbi request reprint Prevalence of restless legs syndrome and REM sleep behavior disorder in multiple sclerosis
    M J Gómez-Choco
    Service of Neurology, Hospital Clinic, Institut d Investigacio Biomedica August Pi i Sunyer, Universitat de Barcelona, Barcelona, Spain
    Mult Scler 13:805-8. 2007
    ..Our study shows that RLS in MS is not more frequent than in the general population, and that RBD, although uncommon, may occur in the setting of this neurological disease...
  26. doi request reprint Anti-Hu-associated brainstem encephalitis
    A Saiz
    Servei de Neurologia, Hospital Clinic, Barcelona, Spain
    J Neurol Neurosurg Psychiatry 80:404-7. 2009
    ..A series of patients with anti-Hu-associated brainstem encephalitis is reviewed to better define the clinical presentation and to improve its recognition...
  27. ncbi request reprint Clinical and genetic features of human prion diseases in Catalonia: 1993-2002
    R Sanchez-Valle
    Services of Neurology, Institut d Investigació Biomédica August Pi i Sunyer IDABAPS, Hospital Clinic, University of Barcelona, Barcelona, Spain
    Eur J Neurol 11:649-55. 2004
    ..No case of variant CJD was registered. The study confirms in our population the consistent pattern reported worldwide on human prion diseases. Atypical features were seen more frequently in sporadic 129 V/V CJD and fCJD cases...
  28. ncbi request reprint [Chronic relapsing inflammatory optic neuropathy (CRION) without detection of IgG-NMO antibodies]
    H Pérez-Díaz
    Servicio de Neurologia, Hospitales Universitarios Virgen del Rocio, Sevilla, Spain
    Neurologia 22:553-5. 2007
    ..We report a 43-year-old man who suffered from several ON episodes affecting one eye or the other. These ON attacks completely disappeared with steroid therapy but relapsed after its withdrawal. IgG-NMO antibodies were negative...
  29. doi request reprint A guide to treating gait impairment with prolonged-release fampridine (Fampyra®) in patients with multiple sclerosis
    L Ramió-Torrentà
    Unitat de Neuroimmunologia i Esclerosi Múltiple, Servicio de Neurologia, Hospital Universitari Dr Josep Trueta, Institut d Investigacio Biomedica de Girona IdIBGi, Girona, España Electronic address
    Neurologia . 2016
    ..This guide aims to provide recommendations on how to evaluate gait impairment and use prolonged-release fampridine (PR-fampridine) as treatment for MS patients with gait impairment in Spain...
  30. ncbi request reprint [HLA-DRB1 typing in Caucasians patients with neuromyelitis optica]
    Y Blanco
    Servicio de Neurologia, Hospital Clínicm, Barcelona, Espana
    Rev Neurol 53:146-52. 2011
    ..Our study was aimed to analyze HLA-DRB1 distribution in Caucasians NMO patients...
  31. doi request reprint Value of NMO-IgG determination at the time of presentation as CIS
    C Costa
    Unitat de Neuroimmunologia Clinica UNIC, Centre d Esclerosi Mu ltiple de Catalunya, Vall d Hebron Institut de Recerca, Barcelona, Spain
    Neurology 78:1608-11. 2012
    ..Despite the availability of diagnostic criteria, an overlap between neuromyelitis optica (NMO) and multiple sclerosis (MS) exists, particularly in the early stage of the disease...
  32. ncbi request reprint Evolution of brain-derived neurotrophic factor levels after autologous hematopietic stem cell transplantation in multiple sclerosis
    Y Blanco
    Services of Neurology, Hospital Clinic, Villarroel 170, Barcelona 08036, Spain
    Neurosci Lett 380:122-6. 2005
    ..Our study suggests that AHSCT can reduce BDNF levels to values associated with lower activity. This decrease does not seem to correlate with the brain atrophy measures observed in the MRI...
  33. doi request reprint Analysis of antibodies to neuronal surface antigens in adult opsoclonus-myoclonus
    L Sabater
    Service of Neurology, Hospital Clinic, Universitat de Barcelona, and Institut d Investigació Biomèdica August Pi i Sunye, Barcelona, Spain
    J Neuroimmunol 196:188-91. 2008
    ..OMS sera did not label live CGN by immunocytochemistry. Unlike pediatric OMS, NSA-ab were not detected in adult cases suggesting that the immunity to NSA in OMS is heterogeneous...
  34. doi request reprint Midbrain lesions and paroxysmal dysarthria in multiple sclerosis
    Y Blanco
    Service of Neurology, Hospital Clinic, Universitat de Barcelona and IDIBAPS, Villaroel 170, Barcelona, Spain
    Mult Scler 14:694-7. 2008
    ..All three patients had an acute lower midbrain lesion. The location was central in two patients and left paramedian in the other, and probably involving cerebellothalamocortical pathways. Treatment with carbamazepine was effective...
  35. pmc GABA(B) receptor antibodies in limbic encephalitis and anti-GAD-associated neurologic disorders
    A Boronat
    Servei de Neurologia, Hospital Clinic, Villarroel 170, Barcelona 08036, Spain
    Neurology 76:795-800. 2011
    ..We analyzed the frequency of GABA(B)R-ab in 147 patients with LE or neurologic syndromes associated with GAD-ab...
  36. ncbi request reprint [Transplantation of haematopoietic stem cells in multiple sclerosis]
    A Saiz
    Servicio de Neurologia, Institut d Investigacio Biomedica August Pi i Sunyer, Hospital Clinic de Barcelona, Barcelona, Espana
    Rev Neurol 35:1136-41. 2002
    ..In any case, this treatment cannot be considered to cure the MS since the probability of patients having no signs of active disease 3 years after transplantation is 12% in SP MS and 0% in PP MS...
  37. ncbi request reprint Homer 3 autoimmunity in subacute idiopathic cerebellar ataxia
    L Zuliani
    Service of Neurology, Hospital Clinic, Universitat de Barcelona and Institut d Investigació Biomèdica August Pi i Sunyer IDIBAPS, Barcelona, Spain
    Neurology 68:239-40. 2007
  38. doi request reprint Analysis of relapses in anti-NMDAR encephalitis
    I Gabilondo
    Center for Neuroimmunology, Service of Neurology, Hospital Clinic and Institut d Investigació Biomèdica August Pi i Sunyer, Barcelona, Spain
    Neurology 77:996-9. 2011
    ..The clinical characteristics of patients with relapsing anti-NMDA receptor (NMDAR) encephalitis are not well-defined. In this study, we report the clinical profile and outcome of relapses in a series of anti-NMDAR encephalitis...
  39. doi request reprint Monoclonal antibody therapy-associated neurological disorders
    Xavier Bosch
    Department of Internal Medicine, University of Barcelona, Villarroel 170, 08036 Barcelona, Spain
    Nat Rev Neurol 7:165-72. 2011
    ....
  40. doi request reprint Antibodies and neuronal autoimmune disorders of the CNS
    Francesc Graus
    Servei de Neurologia, Hospital Clinic, Institut d Investigacio Biomedica August Pi i Sunyer, Villarroel 170, 08036, Barcelona, Spain
    J Neurol 257:509-17. 2010
    ....
  41. ncbi request reprint [MM1 variant of sporadic Creutzfeldt-Jakob disease with long duration akinetic mutism state]
    R Sanchez-Valle
    Unit de ECJ, Servei de Neurologia, Hospital Clinic, Institut d Investgació, Biomedica August Pi i Sunyer, Universitat de Barcelona
    Neurologia 21:444-6. 2006
    ....
  42. doi request reprint Chitinase 3-like 1 plasma levels are increased in patients with progressive forms of multiple sclerosis
    E Canto
    Centre d esclerosi multiple de Catalunya, CEM Cat, Unitat de Neuroimmunologia Clinica, Hospital Universitari Vall d Hebron HUVH, Universitat Autonoma de Barcelona, Barcelona, Spain
    Mult Scler 18:983-90. 2012
    ..Chitinase 3-like 1 (CHI3L1) is upregulated in a wide variety of inflammatory conditions. Recent studies have pointed to a role of CHI3L1 in multiple sclerosis (MS) pathogenesis...
  43. ncbi request reprint [NMO-IgG antibodies in neuromyelitis optica: a report of 2 cases]
    L Zuliani
    Servicio de Neurologia, Hospital Clinico, Barcelona, Spain
    Neurologia 21:314-7. 2006
    ..The antigen responsible for this immune response seems to be aquaporin-4 water channel...
  44. doi request reprint Onset-adjusted incidence of multiple sclerosis in the Girona province (Spain): Evidence of increasing risk in the south of Europe
    S Otero-Romero
    Multiple Sclerosis Centre of Catalonia Cemcat, Department of Neurology Neuroimmunology, Vall d Hebron University Hospital, Barcelona, Spain Preventive Medicine and Epidemiology Department, Vall d Hebron University Hospital, Barcelona, Spain Electronic address
    J Neurol Sci 359:146-50. 2015
    ..The aim of this study was to determine the onset-adjusted incidence of MS in the Girona province in Catalonia (Spain)...
  45. ncbi request reprint P/Q type calcium-channel antibodies in paraneoplastic cerebellar degeneration with lung cancer
    F Graus
    Services of Neurology, Hospital Clinic, Universitat de Barcelona and Institut d Investigació Biomèdica August Pi i Sunyer IDIBAPS, Barcelona, Spain
    Neurology 59:764-6. 2002
    ..Seven of 15 CSF samples had VGCC antibodies, with evidence of intrathecal synthesis in four. VGCC antibodies should be looked for in PCD, even if there are no symptoms of LEMS, and may be related to the cerebellar dysfunction...
  46. doi request reprint Spectrum of neurological syndromes associated with glutamic acid decarboxylase antibodies: diagnostic clues for this association
    Albert Saiz
    Service of Neurology, Hospital Clinic and Institut d Investigació Biomèdica August Pi i Sunyer IDIBAPS, Barcelona, Spain
    Brain 131:2553-63. 2008
    ..Lastly, in patients who develop neurological syndromes that suggest a PNS, the finding of GAD-ab does not rule out this possibility and appropriate studies should be done to confirm an underlying cancer...
  47. doi request reprint Cytotoxic effect of neuromyelitis optica antibody (NMO-IgG) to astrocytes: an in vitro study
    Lidia Sabater
    Service of Neurology, Hospital Clinic, Universitat de Barcelona and Institut d Investigació Biomèdica August Pi i Sunyer, Spain
    J Neuroimmunol 215:31-5. 2009
    ..Our data show that NMO-IgG induces a complement-dependent cytotoxicity of astrocytes in vitro, and suggest that a mechanism of cellular death by necrosis might be implicated in the pathophysiology of NMO...
  48. doi request reprint Anti-Ma and anti-Ma2-associated paraneoplastic neurological syndromes
    G Ortega Suero
    Servicio de Neurologia, Hospital Clinico San Carlos, Madrid, España Electronic address
    Neurologia . 2016
    ..Analyse the clinical profile, associated tumour types, and response to treatment of paraneoplastic neurological syndromes associated with antibodies against Ma proteins...
  49. doi request reprint Color vision impairment in multiple sclerosis points to retinal ganglion cell damage
    E J Lampert
    Center of Neuroimmunology and Department of Neurology, August Pi Sunyer Institute of Biomedical Research, Hospital Clinic of Barcelona, University of Barcelona, Villaroel 170, Barcelona, ES 08036, Spain
    J Neurol 262:2491-7. 2015
    ..Dyschromatopsia in NON-eyes is due to damage of retinal ganglion cells (RGC) in MS. Color vision can serve as a marker of RGC damage in MS...
  50. ncbi request reprint Detection of 14-3-3 protein in the CSF of a patient with Hashimoto's encephalopathy
    L E Hernández Echebarría
    Service of Neurology, Hospital de Leon, Barcelona, Spain
    Neurology 54:1539-40. 2000
  51. ncbi request reprint [Limbic encephalitis: a probably under-recognized syndrome]
    F Graus
    Servicio de Neurologia, Hospital Clinic, Barcelona
    Neurologia 20:24-30. 2005
    ..On the contrary, immunosuppressant treatment is not usually effective in limbic encephalitis associated to anti-Hu antibodies...
  52. ncbi request reprint Corticosteroids, ibuprofen, and acetaminophen for IFNbeta-1a flu symptoms in MS: a randomized trial
    J Rio
    Centres H Vall d Hebron, Barcelona, Spain
    Neurology 63:525-8. 2004
    ..To compare the efficacy of acetaminophen, ibuprofen, and prednisone in the treatment of interferon beta-1a (IFNbeta-1a) flu-like syndrome (FLS)...
  53. ncbi request reprint Changes of matrix metalloproteinase-9 and its tissue inhibitor (TIMP-1) after autologous hematopoietic stem cell transplantation in multiple sclerosis
    Yolanda Blanco
    Services of Neurology, Hospital Clinic, Institut d Investigacio Biomedica August Pi i Sunyer IDIBAPS, University of Barcelona, Villarroel 170, Barcelona 08036, Spain
    J Neuroimmunol 153:190-4. 2004
    ..MMP-9 mRNA levels correlated with the CD4+ T cell count (p<0.0001). The significant and persistent change in MMP-9 activity after AHSCT may be caused in part by the effect of AHSCT in the CD4+ T cell count...
  54. pmc ZIC antibodies in paraneoplastic cerebellar degeneration and small cell lung cancer
    Lidia Sabater
    Service of Neurology Hospital Clinic, Universitat de Barcelona and Institut d Investigació Biomèdica August Pi i Sunyer IDIBAPS, Barcelona, Spain
    J Neuroimmunol 201:163-5. 2008
    ..Our study suggests that 1) the incidence of isolated ZIC antibodies is low in PCD patients and SCLC and 2) ZIC antibodies are probably directed to epitopes shared by the three ZIC proteins...
  55. ncbi request reprint Autologous haematopoietic-stem-cell transplantation for multiple sclerosis
    Yolanda Blanco
    Service of Neurology, Hospital Clinic, Institut d Investigacio Biomedica August Pi i Sunyer, University of Barcelona, Spain
    Lancet Neurol 4:54-63. 2005
    ..The course of MS seems to be stabilised after autologous HSCT, especially in ambulatory patients with evidence of active disease. Autologous HSCT deserves further study in randomised controlled trials...
  56. ncbi request reprint Tau protein in cerebrospinal fluid: a possible marker of poor outcome in patients with early relapsing-remitting multiple sclerosis
    Antonio Martínez-Yélamos
    Department of Neurology, Hospital de Viladecans, Av Gava 380 08840 Viladecans, Barcelona, Spain
    Neurosci Lett 363:14-7. 2004
    ..CSF-TAU was the only independent variable to predict the time to next relapse. CSF-TAU, as a marker of axonal loss, may help us to predict short-term outcome in patients with early RRMS...
  57. ncbi request reprint No association of inducible nitric oxide synthase gene ( NOS2A) to multiple sclerosis
    Yolanda Blanco
    Servei de Neurologia, Hospital Clinic, Villarroel 170, Barcelona 08036, Spain
    J Neurol 250:598-600. 2003
    ..No association was found between MS susceptibility, course or outcome of the disease, and NOS2A polymorphisms...
  58. ncbi request reprint Carbonic anhydrase-related protein VIII: autoantigen in paraneoplastic cerebellar degeneration
    Luis Bataller
    Service of Neurology, Hospital Clinic, Universitat de Barcelona and Institut d Investigació Biomèdica August Pi i Sunyer, Barcelona, Spain
    Ann Neurol 56:575-9. 2004
    ..The patient had intrathecal synthesis of CARP VIII antibodies. One of seven melanomas tested expressed CARP VIII. These data suggest CARP VIII may be an autoantigen involved in the pathogenesis of melanoma-associated PCD...
  59. doi request reprint Cannabis use in Spanish patients with multiple sclerosis: fulfilment of patients' expectations?
    Jose E Martinez-Rodriguez
    Neurology Service, Hospital del Mar, Institut Municipal d Investigacio Medica IMIM, Barcelona, Spain
    J Neurol Sci 273:103-7. 2008
    ..The aim of the study was to evaluate the prevalence of cannabis use, related factors, and degree of satisfaction in Spanish patients with multiple sclerosis (MS) prior to the establishment of medically supervised use...
  60. ncbi request reprint Immunohistochemical analysis of anti-Hu-associated paraneoplastic encephalomyelitis
    Fabian Bernal
    Service of Neurology, Hospital Clinic Barcelona, Universitat de Barcelona, and Institut d Investigació Biomèdica August Pi i Sunyer, Villarroel 170, 08036 Barcelona, Spain
    Acta Neuropathol 103:509-15. 2002
    ..Our data point out to an induction of a cytotoxic, non-apoptotic, neuronal death in anti-Hu-associated PEM. The increased ICAM-1 immunoreactivity may favor the infiltration of lymphocytes in the pathological areas...
  61. ncbi request reprint BR serine/threonine kinase 2: a new autoantigen in paraneoplastic limbic encephalitis
    Lidia Sabater
    Service of Neurology, Hospital Clinic, Universitat de Barcelona and Institut d Investigació Biomèdica August Pi i Sunyer IDIBAPS, Barcelona, Spain
    J Neuroimmunol 170:186-90. 2005
    ..Our study suggests BRSK2 may be an autoantigen involved in the pathogenesis of SCLC-associated limbic encephalitis...
  62. ncbi request reprint [Rapidly progressive visual disorder and cognitive impairment in a 66-year-old woman]
    Juan Jose Zarranz
    Servicio de Neurologia, Hospital de Cruces Baracaldo Vizcaya España
    Med Clin (Barc) 119:149-57. 2002
  63. ncbi request reprint Discrepancies in the clinical utility of the 14-3-3 protein for the diagnosis of sporadic Creutzfeldt-Jakob disease
    Raquel Sanchez-Valle
    Arch Neurol 61:604. 2004
  64. ncbi request reprint Clinical analysis of anti-Ma2-associated encephalitis
    Josep Dalmau
    Department of Neurology, 3 W Gates, Division of Neuro Oncology, University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104, USA
    Brain 127:1831-44. 2004
    ..In young male patients, the primary tumour is usually in the testis, in other patients the leading neoplasm is lung cancer...
  65. pmc Paraneoplastic limbic encephalitis associated with potassium channel antibodies: value of anti-glial nuclear antibodies in identifying the tumour
    Luigi Zuliani
    J Neurol Neurosurg Psychiatry 78:204-5. 2007
  66. ncbi request reprint Fatal familial insomnia
    Vanessa Sanchez Gistau
    Department of Psychiatry, Hospital Clinico de Barcelona Barcelona, Spain
    Psychosomatics 47:527-8. 2006
  67. ncbi request reprint P/Q-type calcium channel antibodies, Lambert-Eaton myasthenic syndrome and survival in small cell lung cancer
    Paul W Wirtz
    Department of Neurology, Leiden University Medical Center, P O Box 9600, 2300 RC Leiden, The Netherlands
    J Neuroimmunol 164:161-5. 2005
    ..In both series, only patients with LEMS had a remarkably long survival, whereas presence of the antibodies without LEMS did not result in a better prognosis...
  68. ncbi request reprint Acute disseminated encephalomyelitis associated with Campylobacter jejuni infection and antiganglioside GM1 IgG antibodies
    Carles Gaig
    J Neurol 252:613-4. 2005