Jahit Sacarlal

Summary

Country: Spain

Publications

  1. doi request reprint Long-term safety and efficacy of the RTS,S/AS02A malaria vaccine in Mozambican children
    Jahit Sacarlal
    Centro de Investigação em Saúde de Manhiça CISM Manhiça, Mozambique
    J Infect Dis 200:329-36. 2009
  2. pmc A 10 year study of the cause of death in children under 15 years in Manhiça, Mozambique
    Jahit Sacarlal
    Centro de Investigação em Saúde da Manhiça CISM, Mozambique
    BMC Public Health 9:67. 2009
  3. ncbi request reprint Safety of the RTS,S/AS02A malaria vaccine in Mozambican children during a Phase IIb trial
    Jahit Sacarlal
    Centro de Investigação em Saúde de Manhiça, Manhiça, Mozambique
    Vaccine 26:174-84. 2008
  4. pmc Assessment of exposure to DDT and metabolites after indoor residual spraying through the analysis of thatch material from rural African dwellings
    Maria N Manaca
    Centro de Investigação em Saúde da Manhiça CISM, Maputo, Mozambique
    Environ Sci Pollut Res Int 19:756-62. 2012
  5. doi request reprint Four year immunogenicity of the RTS,S/AS02(A) malaria vaccine in Mozambican children during a phase IIb trial
    Pedro Aide
    Centro de Investigação em Saúde de Manhiça CISM, Manhiça, Mozambique
    Vaccine 29:6059-67. 2011
  6. pmc Plasmodium falciparum-specific cellular immune responses after immunization with the RTS,S/AS02D candidate malaria vaccine in infants living in an area of high endemicity in Mozambique
    Arnoldo Barbosa
    Centro de Investigação en Saúde de Manhiça, Manhiça, Mozambique
    Infect Immun 77:4502-9. 2009
  7. pmc Evaluation of two formulations of adjuvanted RTS, S malaria vaccine in children aged 3 to 5 years living in a malaria-endemic region of Mozambique: a Phase I/IIb randomized double-blind bridging trial
    Eusébio V Macete
    Centro de Investigação em Saúde de Manhiça, Manhiça, Mozambique
    Trials 8:11. 2007
  8. doi request reprint Population characteristics of young African women influencing prenatal exposure to DDT (Manhiça, Mozambique)
    Maria N Manaca
    Centro de Investigação em Saúde da Manhiça, Maputo, Mozambique
    Environ Sci Pollut Res Int 20:3472-9. 2013
  9. doi request reprint Profile: Manhiça Health Research Centre (Manhiça HDSS)
    Charfudin Sacoor
    Manhiça Health Research Centre, Manhiça District, Mozambique, Barcelona Centre for International Health Research, Hospital Clínic Universitat de Barcelona, Spain, National Directorate of Health, Ministry of Health, Maputo, Mozambique, National Institute of Health, Ministry of Health, Maputo Mozambique and Faculty of Medicine, Eduardo Mondlane University, Maputo, Mozambique
    Int J Epidemiol 42:1309-18. 2013
  10. pmc Safety, immunogenicity and duration of protection of the RTS,S/AS02(D) malaria vaccine: one year follow-up of a randomized controlled phase I/IIb trial
    Pedro Aide
    Centro de Investigação em Saúde da Manhiça, Maputo, Mozambique
    PLoS ONE 5:e13838. 2010

Collaborators

Detail Information

Publications21

  1. doi request reprint Long-term safety and efficacy of the RTS,S/AS02A malaria vaccine in Mozambican children
    Jahit Sacarlal
    Centro de Investigação em Saúde de Manhiça CISM Manhiça, Mozambique
    J Infect Dis 200:329-36. 2009
    ..We previously reported that the RTS,S/AS02A vaccine had an acceptable safety profile, was immunogenic, and demonstrated efficacy against Plasmodium falciparum malaria disease for 21 months...
  2. pmc A 10 year study of the cause of death in children under 15 years in Manhiça, Mozambique
    Jahit Sacarlal
    Centro de Investigação em Saúde da Manhiça CISM, Mozambique
    BMC Public Health 9:67. 2009
    ....
  3. ncbi request reprint Safety of the RTS,S/AS02A malaria vaccine in Mozambican children during a Phase IIb trial
    Jahit Sacarlal
    Centro de Investigação em Saúde de Manhiça, Manhiça, Mozambique
    Vaccine 26:174-84. 2008
    ..Overall, these results indicate that the RTS,S/AS02A vaccine has a good safety profile and well tolerated when given in three doses to semi-immune children living in malaria-endemic areas...
  4. pmc Assessment of exposure to DDT and metabolites after indoor residual spraying through the analysis of thatch material from rural African dwellings
    Maria N Manaca
    Centro de Investigação em Saúde da Manhiça CISM, Maputo, Mozambique
    Environ Sci Pollut Res Int 19:756-62. 2012
    ..This approach was used to assess the exposure to DDT in the residents of the dwellings after indoor residual spraying (IRS) following recommended sanitation practices against malaria vectors...
  5. doi request reprint Four year immunogenicity of the RTS,S/AS02(A) malaria vaccine in Mozambican children during a phase IIb trial
    Pedro Aide
    Centro de Investigação em Saúde de Manhiça CISM, Manhiça, Mozambique
    Vaccine 29:6059-67. 2011
    ..RTS,S/AS02(A) vaccine is immunogenic and induces long-lasting anti-circumsporozoite antibodies, persisting at least 42 months after immunization. These antibodies may play a role in protection against malaria...
  6. pmc Plasmodium falciparum-specific cellular immune responses after immunization with the RTS,S/AS02D candidate malaria vaccine in infants living in an area of high endemicity in Mozambique
    Arnoldo Barbosa
    Centro de Investigação en Saúde de Manhiça, Manhiça, Mozambique
    Infect Immun 77:4502-9. 2009
    ....
  7. pmc Evaluation of two formulations of adjuvanted RTS, S malaria vaccine in children aged 3 to 5 years living in a malaria-endemic region of Mozambique: a Phase I/IIb randomized double-blind bridging trial
    Eusébio V Macete
    Centro de Investigação em Saúde de Manhiça, Manhiça, Mozambique
    Trials 8:11. 2007
    ..25 ml dose). A 0.5 ml dose of AS02D is composed of the same active ingredients in the same quantities as in a 0.25 ml dose of AS02A and has been developed to be easily introduced into routine EPI practices...
  8. doi request reprint Population characteristics of young African women influencing prenatal exposure to DDT (Manhiça, Mozambique)
    Maria N Manaca
    Centro de Investigação em Saúde da Manhiça, Maputo, Mozambique
    Environ Sci Pollut Res Int 20:3472-9. 2013
    ..Children from multiparae women showed much lower concentrations than primiparae women. Children from mothers with secondary school level exhibited lower concentrations of these pesticides than mothers with lower degree of education...
  9. doi request reprint Profile: Manhiça Health Research Centre (Manhiça HDSS)
    Charfudin Sacoor
    Manhiça Health Research Centre, Manhiça District, Mozambique, Barcelona Centre for International Health Research, Hospital Clínic Universitat de Barcelona, Spain, National Directorate of Health, Ministry of Health, Maputo, Mozambique, National Institute of Health, Ministry of Health, Maputo Mozambique and Faculty of Medicine, Eduardo Mondlane University, Maputo, Mozambique
    Int J Epidemiol 42:1309-18. 2013
    ..Manhiça's data can be accessed through a formal request to Diana Quelhas (diana.quelhas@manhica.net) accompanied by a proposal that will be analysed by the Manhiça HDSS internal scientific and ethics committees. ..
  10. pmc Safety, immunogenicity and duration of protection of the RTS,S/AS02(D) malaria vaccine: one year follow-up of a randomized controlled phase I/IIb trial
    Pedro Aide
    Centro de Investigação em Saúde da Manhiça, Maputo, Mozambique
    PLoS ONE 5:e13838. 2010
    ..The RTS,S/AS02(D) vaccine has been shown to have a promising safety profile, to be immunogenic and to confer protection against malaria in children and infants...
  11. pmc Antimicrobial drug resistance trends of bacteremia isolates in a rural hospital in southern Mozambique
    Inacio Mandomando
    Centro de Investigação em Saúde da Manhiça, Vila da Manhiça, Rua 12, PO Box 1929, Maputo, Mozambique
    Am J Trop Med Hyg 83:152-7. 2010
    ..Quinolones and third-generation cephalosporines may be needed in the short term to manage community-acquired infections...
  12. doi request reprint Invasive non-typhoidal Salmonella in Mozambican children
    Inacio Mandomando
    Centro de Investigação em Saúde da Manhiça CISM, Maputo, Moçambique
    Trop Med Int Health 14:1467-74. 2009
    ..To describe the epidemiology and clinical presentation of invasive non-typhoidal Salmonella (NTS) in Mozambique...
  13. ncbi request reprint Etiology of diarrhea in children younger than 5 years of age admitted in a rural hospital of southern Mozambique
    Inácio M Mandomando
    Centro de Investigação em Saúde da Manhiça, Moçambique
    Am J Trop Med Hyg 76:522-7. 2007
    ..Resistance to trimethoprim-sulphametoxazole and ampicillin was high. Etiologic data on diarrheal diseases and susceptibility patterns of diarrheal pathogens are important tools for clinical management and control strategic planning...
  14. pmc Antimicrobial susceptibility and mechanisms of resistance in Shigella and Salmonella isolates from children under five years of age with diarrhea in rural Mozambique
    Inacio Mandomando
    Centro de Investigação em Saúde da Manhiça, Vila da Manhiça, Rua 12, P O Box 1929, Maputo, Mozambique
    Antimicrob Agents Chemother 53:2450-4. 2009
    ....
  15. doi request reprint Community-acquired bacteremia among children admitted to a rural hospital in Mozambique
    Betuel Sigauque
    Centro de Investigação em Saúde da Manhiça, Maputo, Mozambique
    Pediatr Infect Dis J 28:108-13. 2009
    ..Although community-acquired bacteremia is an important cause of childhood mortality in Africa, recognition of disease burden and potential impact of bacterial vaccines is limited...
  16. pmc Malaria in rural Mozambique. Part II: children admitted to hospital
    Quique Bassat
    Barcelona Center for International Health Research CRESIB, Hospital Clinic Institut d Investigacions Biomediques August Pi i Sunyer, University of Barcelona, Rosselló 132, E 08036 Barcelona, Spain
    Malar J 7:37. 2008
    ..Minimum community based-incidence rates (MCBIRs) complement hospital data, describing the malaria burden in the community...
  17. ncbi request reprint Epidemiology and clinical presentation of shigellosis in children less than five years of age in rural Mozambique
    Inacio Mandomando
    Centro de Investigação em Saúde da Manhiça, IDIBAPS Hospital Clinic, Universitat de Barcelona, Barcelona, Spain
    Pediatr Infect Dis J 26:1059-61. 2007
    ..7% versus 0.4%, P = 0.004), and from dysentery than nondysenteric diarrhea (24.1% versus 3.5%, P < 0.001). Shigella flexneri 2a, S. sonnei, and S. flexneri 6, were the most prevalent serotypes...
  18. pmc Prevalence and risk factors of sexually transmitted infections and cervical neoplasia in women from a rural area of southern Mozambique
    Clara Menendez
    Manhiça Health Research Center, Manhiça, Maputo, Mozambique
    Infect Dis Obstet Gynecol 2010:. 2010
    ..A higher prevalence was observed in the reproductive age group and some of the STIs were more frequently diagnosed in pregnant women. STI control programs are a priority to reduce the STIs burden, including HIV and cervical neoplasia...
  19. ncbi request reprint Antimicrobial resistance of Vibrio cholerae O1 serotype Ogawa isolated in Manhiça District Hospital, southern Mozambique
    Inacio Mandomando
    Centro de Investigação em Saúde da Manhiça CISM, Maputo, Mozambique
    J Antimicrob Chemother 60:662-4. 2007
    ..To describe the antimicrobial susceptibility profile of isolated Vibrio cholerae O1 serotype Ogawa recovered from patients admitted to the cholera facility in the Manhiça District Hospital (MDH), Mozambique...
  20. pmc RTS,S vaccination is associated with serologic evidence of decreased exposure to Plasmodium falciparum liver- and blood-stage parasites
    Joe J Campo
    ISGlobal, Barcelona Ctr Int Health Res CRESIB, Hospital Clínic Universitat de Barcelona, Barcelona, Spain Manhiça Health Research Centre, Manhiça, Mozambique
    Mol Cell Proteomics 14:519-31. 2015
    ..Together, these data provide insight into the mechanism by which RTS,S protects from malaria. ..
  21. doi request reprint Concentration of DDT compounds in breast milk from African women (Manhiça, Mozambique) at the early stages of domestic indoor spraying with this insecticide
    Maria N Manaca
    Centro de Investigação em Saúde da Manhiça CISM, Maputo, Mozambique
    Chemosphere 85:307-14. 2011
    ..These differences overcome the age effect in DDT accumulation between the two groups and evidence that women transfer a significant proportion of their body burden of DDT and its metabolites to their infants...