Aneta Ringholm

Summary

Country: Spain

Publications

  1. pmc Molecular characterization and functional regulation of melanocortin 2 receptor (MC2R) in the sea bass. A putative role in the adaptation to stress
    Maria Josep Agulleiro
    Department of Fish Physiology and Biotechnology, Instituto de Acuicultura de Torre de la Sal, Consejo Superior de Investigaciones Científicas IATS CSIC, Castellon, Spain
    PLoS ONE 8:e65450. 2013
  2. pmc Transient ectopic overexpression of agouti-signalling protein 1 (asip1) induces pigment anomalies in flatfish
    Raul Guillot
    Department of Fish Physiology and Biotechnology, Instituto de Acuicultura de Torre de la Sal, Consejo Superior de Investigaciones Cientificas, Castellon, Spain
    PLoS ONE 7:e48526. 2012
  3. doi request reprint Involvement of melanocortin receptor accessory proteins (MRAPs) in the function of melanocortin receptors
    J M Cerdá-Reverter
    Department of Fish Physiology and Biotechnology, Instituto de Acuicultura de Torre de la Sal, Consejo Superior de Investigaciones Científicas IATS CSIC, 12595 Torre de la Sal, Ribera de Cabanes, Castellon, Spain
    Gen Comp Endocrinol 188:133-6. 2013
  4. doi request reprint Fish melanocortin system
    Jose Miguel Cerdá-Reverter
    Department of Fish Physiology and Biotechnology, Instituto de Acuicultura de Torre de la Sal IATS, Consejo Superior de Investigaciones Cientificas CSIC, Castellon, Spain
    Eur J Pharmacol 660:53-60. 2011
  5. ncbi request reprint Regulation of the hypothalamic melanin-concentrating hormone neurons by sex steroids in the goldfish: possible role in the modulation of luteinizing hormone secretion
    Jose Miguel Cerdá-Reverter
    Department of Biological Sciences, University of Alberta, Edmonton, Alta, Canada
    Neuroendocrinology 84:364-77. 2006
  6. ncbi request reprint Gene structure of the goldfish agouti-signaling protein: a putative role in the dorsal-ventral pigment pattern of fish
    Jose Miguel Cerdá-Reverter
    Department of Fish Reproductive Physiology, Instituto de Acuicultura de Torre de la Sal, Consejo Superior de Investigaciones Cientificas, 12595 Torre de la Sal, Ribera de Cabanes, Castellon, Spain
    Endocrinology 146:1597-610. 2005
  7. ncbi request reprint Neuropeptide Y family of peptides: structure, anatomical expression, function, and molecular evolution
    J M Cerdá-Reverter
    Department of Fish Reproductive Physiology, Instituto de Acuicultura de Torre de la Sal, Castellon, Spain
    Biochem Cell Biol 78:371-92. 2000
  8. ncbi request reprint The central melanocortin system regulates food intake in goldfish
    Jose Miguel Cerdá-Reverter
    Department of Biological Sciences, University of Alberta, T6G 2E9, Edmonton, Alberta, Canada
    Regul Pept 115:101-13. 2003
  9. ncbi request reprint Endogenous melanocortin antagonist in fish: structure, brain mapping, and regulation by fasting of the goldfish agouti-related protein gene
    Jose Miguel Cerdá-Reverter
    Department of Biological Sciences, University of Alberta, Edmonton, Canada T6G 2E9
    Endocrinology 144:4552-61. 2003
  10. ncbi request reprint Molecular cloning, pharmacological characterization, and brain mapping of the melanocortin 4 receptor in the goldfish: involvement in the control of food intake
    Jose Miguel Cerdá-Reverter
    Department of Biological Sciences, University of Alberta, Edmonton, Alberta, T6G 2E9 Canada
    Endocrinology 144:2336-49. 2003

Collaborators

Detail Information

Publications19

  1. pmc Molecular characterization and functional regulation of melanocortin 2 receptor (MC2R) in the sea bass. A putative role in the adaptation to stress
    Maria Josep Agulleiro
    Department of Fish Physiology and Biotechnology, Instituto de Acuicultura de Torre de la Sal, Consejo Superior de Investigaciones Científicas IATS CSIC, Castellon, Spain
    PLoS ONE 8:e65450. 2013
    ..ACTH-induced MC2R activation stimulates hepatic lipolysis, suggesting that ACTH may mediate stress-induced effects upstream of cortisol release...
  2. pmc Transient ectopic overexpression of agouti-signalling protein 1 (asip1) induces pigment anomalies in flatfish
    Raul Guillot
    Department of Fish Physiology and Biotechnology, Instituto de Acuicultura de Torre de la Sal, Consejo Superior de Investigaciones Cientificas, Castellon, Spain
    PLoS ONE 7:e48526. 2012
    ..This, in turn, generates a ventral-like differentiation environment in dorsal regions...
  3. doi request reprint Involvement of melanocortin receptor accessory proteins (MRAPs) in the function of melanocortin receptors
    J M Cerdá-Reverter
    Department of Fish Physiology and Biotechnology, Instituto de Acuicultura de Torre de la Sal, Consejo Superior de Investigaciones Científicas IATS CSIC, 12595 Torre de la Sal, Ribera de Cabanes, Castellon, Spain
    Gen Comp Endocrinol 188:133-6. 2013
    ..MRAPs also interact with the other melanocortin receptors, adjusting their pharmacological properties. In this paper, we briefly review the MRAP system and its interaction with melanocortin receptors...
  4. doi request reprint Fish melanocortin system
    Jose Miguel Cerdá-Reverter
    Department of Fish Physiology and Biotechnology, Instituto de Acuicultura de Torre de la Sal IATS, Consejo Superior de Investigaciones Cientificas CSIC, Castellon, Spain
    Eur J Pharmacol 660:53-60. 2011
    ..Accordingly, the overexpression of AGRP and ASP transgenes promotes obesity and reduces melanization in zebrafish, respectively...
  5. ncbi request reprint Regulation of the hypothalamic melanin-concentrating hormone neurons by sex steroids in the goldfish: possible role in the modulation of luteinizing hormone secretion
    Jose Miguel Cerdá-Reverter
    Department of Biological Sciences, University of Alberta, Edmonton, Alta, Canada
    Neuroendocrinology 84:364-77. 2006
    ..Results suggest that hypothalamic MCH may participate in the steroid positive feedback loop on pituitary LH secretion...
  6. ncbi request reprint Gene structure of the goldfish agouti-signaling protein: a putative role in the dorsal-ventral pigment pattern of fish
    Jose Miguel Cerdá-Reverter
    Department of Fish Reproductive Physiology, Instituto de Acuicultura de Torre de la Sal, Consejo Superior de Investigaciones Cientificas, 12595 Torre de la Sal, Ribera de Cabanes, Castellon, Spain
    Endocrinology 146:1597-610. 2005
    ..Our studies support agouti signaling protein as the melanization inhibition factor, a key factor in the development of the dorsal-ventral pigment pattern in fish...
  7. ncbi request reprint Neuropeptide Y family of peptides: structure, anatomical expression, function, and molecular evolution
    J M Cerdá-Reverter
    Department of Fish Reproductive Physiology, Instituto de Acuicultura de Torre de la Sal, Castellon, Spain
    Biochem Cell Biol 78:371-92. 2000
    ..Studies in the sea bass and other fish show that PY, in contrast to PP, is expressed in the nervous system. We review the literature on the distribution and functional aspects of the various NPY-family peptides in vertebrates...
  8. ncbi request reprint The central melanocortin system regulates food intake in goldfish
    Jose Miguel Cerdá-Reverter
    Department of Biological Sciences, University of Alberta, T6G 2E9, Edmonton, Alberta, Canada
    Regul Pept 115:101-13. 2003
    ..The conserved central expression pattern of POMC mRNA and role of MSH peptides in physiological regulation of food intake suggests that melanocortin functions were gained early in vertebrate evolution...
  9. ncbi request reprint Endogenous melanocortin antagonist in fish: structure, brain mapping, and regulation by fasting of the goldfish agouti-related protein gene
    Jose Miguel Cerdá-Reverter
    Department of Biological Sciences, University of Alberta, Edmonton, Canada T6G 2E9
    Endocrinology 144:4552-61. 2003
    ....
  10. ncbi request reprint Molecular cloning, pharmacological characterization, and brain mapping of the melanocortin 4 receptor in the goldfish: involvement in the control of food intake
    Jose Miguel Cerdá-Reverter
    Department of Biological Sciences, University of Alberta, Edmonton, Alberta, T6G 2E9 Canada
    Endocrinology 144:2336-49. 2003
    ....
  11. pmc The melanocortin receptor subtypes in chicken have high preference to ACTH-derived peptides
    Maria K Ling
    Department of Neuroscience, Uppsala University, BMC, Box 593, 751 24 Uppsala, Sweden
    Br J Pharmacol 143:626-37. 2004
    ..5 We also show the presence of prohormone convertase 1 (PC1) and PC2 genes in chicken, and that these peptides are coexpressed with proopiomelanocortin (POMC) in various tissues...
  12. ncbi request reprint One melanocortin 4 and two melanocortin 5 receptors from zebrafish show remarkable conservation in structure and pharmacology
    Aneta Ringholm
    Department of Neuroscience, Unit of Pharmacology, Uppsala University, BMC, 75 124 Uppsala, Sweden
    J Neurochem 82:6-18. 2002
    ....
  13. ncbi request reprint Presence of melanocortin (MC4) receptor in spiny dogfish suggests an ancient vertebrate origin of central melanocortin system
    Aneta Ringholm
    Department of Neuroscience, Uppsala University, Uppsala, Sweden
    Eur J Biochem 270:213-21. 2003
    ..Conservation of gene structure, pharmacological properties and tissue distribution suggests that this receptor may have similar roles in sharks as in mammals and that these were established more than 450 million years ago...
  14. ncbi request reprint High diversity in functional properties of melanocortin 1 receptor (MC1R) in divergent primate species is more strongly associated with phylogeny than coat color
    Tatjana Haitina
    Department of Neuroscience, Division of Pharmacology, Biomedical Center, Uppsala University, Uppsala, Sweden
    Mol Biol Evol 24:2001-8. 2007
    ..This diversity of function is broadly associated with primate phylogeny and does not have a simple relation to coat color phenotype within primate clades...
  15. pmc Functional characterization of two melanocortin (MC) receptors in lamprey showing orthology to the MC1 and MC4 receptor subtypes
    Tatjana Haitina
    Department of Neuroscience, Unit of Pharmacology, Uppsala University, BMC, Uppsala, Sweden
    BMC Evol Biol 7:101. 2007
    ..They belong to the rhodopsin family of G protein-coupled receptors (GPCRs). The purpose of this study was to identify ancestral MC receptors in agnathan, river lamprey...
  16. ncbi request reprint Functional role, structure, and evolution of the melanocortin-4 receptor
    Helgi B Schioth
    Department of Neuroscience, Uppsala University, BMC, 751 24, Uppsala, Sweden
    Ann N Y Acad Sci 994:74-83. 2003
    ..The MC-4 receptor has been remarkably conserved in structure and pharmacology for more than 400 million years, implying that the receptor participated in vital physiological functions early in vertebrate evolution...
  17. ncbi request reprint Cloning of two melanocortin (MC) receptors in spiny dogfish: MC3 receptor in cartilaginous fish shows high affinity to ACTH-derived peptides while it has lower preference to gamma-MSH
    Janis Klovins
    Department of Neuroscience, Unit of Pharmacology, Uppsala University, Sweden
    Eur J Biochem 271:4320-31. 2004
    ..The study indicates that many of the important elements of the MC system existed before radiation of gnathostomes, early in vertebrate evolution, at least 450 million years ago...
  18. ncbi request reprint Evolutionary conservation of the structural, pharmacological, and genomic characteristics of the melanocortin receptor subtypes
    Helgi B Schioth
    Department of Neuroscience, Uppsala University, Biomedical Centre, Box 593, SE75124 Uppsala, Sweden
    Peptides 26:1886-900. 2005
    ..In this review, we provide an overview of our recent studies on the cloning, expression, pharmacology, 3D modeling, and genomic studies of the MCRs in non-mammalian species...
  19. ncbi request reprint Pharmacological characterization of loss of function mutations of the human melanocortin 1 receptor that are associated with red hair
    Aneta Ringholm
    Department of Neuroscience, Division of Pharmacology, Uppsala University, Uppsala, Sweden
    J Invest Dermatol 123:917-23. 2004
    ..The results provide important pharmacological characterization of common MC1 receptor variants in various world populations...