Josep M Pique

Summary

Country: Spain

Publications

  1. pmc Reliability and validity of the Gastrointestinal Symptom Rating Scale (GSRS) and Quality of Life in Reflux and Dyspepsia (QOLRAD) questionnaire in dyspepsia: a six-country study
    Károly R Kulich
    AstraZeneca R and D, Medical Science, Molndal, S 431 86, Sweden
    Health Qual Life Outcomes 6:12. 2008
  2. ncbi request reprint [Training of specialists in gastroenterology. Was it time for a review?]
    J M Pique
    Asociación Española de Gastroenterología AEG, Spain
    Gastroenterol Hepatol 26:427-36. 2003
  3. ncbi request reprint [Burden of gastroesophageal reflux disease. Evidence from a recent methodological study in Spain]
    J M Pique
    Servicio de Gastroenterologia, Hospital Clinic, Barcelona, Spain
    Gastroenterol Hepatol 27:300-6. 2004
  4. ncbi request reprint Pharmacokinetics of omeprazole given by continuous intravenous infusion to patients with varying degrees of hepatic dysfunction
    Josep M Pique
    Department of Gastroenterology, Institute of Digestive Diseases, Hospital Clinic, University of Barcelona, Barcelona, Spain
    Clin Pharmacokinet 41:999-1004. 2002
  5. ncbi request reprint Protective effect of superoxide dismutase in radiation-induced intestinal inflammation
    Meritxell Molla
    Department of Gastroenterology, Hospital Clinic, Institut de Investigacions Biomediques August Pi i Sunyer, Barcelona, Spain
    Int J Radiat Oncol Biol Phys 61:1159-66. 2005
  6. ncbi request reprint Nitric oxide supplementation ameliorates dextran sulfate sodium-induced colitis in mice
    Azucena Salas
    Department of Gastroenterology, Institut de Malalties Digestives, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer IDIBAPS, Barcelona, Spain
    Lab Invest 82:597-607. 2002
  7. ncbi request reprint Anti-inflammatory effects of low-dose radiotherapy in an experimental model of systemic inflammation in mice
    Meritxell Arenas
    Department of Radiation Oncology, Hospital Clinic de Barcelona, Institut de Investigacions Biomèdiques August Pi i Sunyer IDIBAPS, University of Barcelona, Barcelona, Spain
    Int J Radiat Oncol Biol Phys 66:560-7. 2006
  8. ncbi request reprint Superoxide dismutase ameliorates TNBS-induced colitis by reducing oxidative stress, adhesion molecule expression, and leukocyte recruitment into the inflamed intestine
    Joaquim Seguí
    Department of Gastroenterology, Hospital Clinic, IDIBAPS, Villarroel 170, 08036 Barcelona, Spain
    J Leukoc Biol 76:537-44. 2004
  9. ncbi request reprint Leukocyte recruitment in colon cancer: role of cell adhesion molecules, nitric oxide, and transforming growth factor beta1
    Xavier Bessa
    Gastroenterology Department, Institut de Malalties Digestives, Hospital Clinic, Institut d Investigacions Biomèdiques Agust Pi i Sunyer, University of Barcelona, Barcelona, Spain
    Gastroenterology 122:1122-32. 2002
  10. ncbi request reprint Effect of cyclosporin A on cell adhesion molecules and leukocyte-endothelial cell interactions in experimental colitis
    Antonio Soriano-Izquierdo
    Department of Gastroenterology, Institut de Malalties Digestives, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer IDIBAPS, University of Barcelona, Barcelona, Spain
    Inflamm Bowel Dis 10:789-800. 2004

Detail Information

Publications56

  1. pmc Reliability and validity of the Gastrointestinal Symptom Rating Scale (GSRS) and Quality of Life in Reflux and Dyspepsia (QOLRAD) questionnaire in dyspepsia: a six-country study
    Károly R Kulich
    AstraZeneca R and D, Medical Science, Molndal, S 431 86, Sweden
    Health Qual Life Outcomes 6:12. 2008
    ....
  2. ncbi request reprint [Training of specialists in gastroenterology. Was it time for a review?]
    J M Pique
    Asociación Española de Gastroenterología AEG, Spain
    Gastroenterol Hepatol 26:427-36. 2003
  3. ncbi request reprint [Burden of gastroesophageal reflux disease. Evidence from a recent methodological study in Spain]
    J M Pique
    Servicio de Gastroenterologia, Hospital Clinic, Barcelona, Spain
    Gastroenterol Hepatol 27:300-6. 2004
    ..The clinical and socioeconomic burden of gastroesophageal reflux disease (GERD) is considerable...
  4. ncbi request reprint Pharmacokinetics of omeprazole given by continuous intravenous infusion to patients with varying degrees of hepatic dysfunction
    Josep M Pique
    Department of Gastroenterology, Institute of Digestive Diseases, Hospital Clinic, University of Barcelona, Barcelona, Spain
    Clin Pharmacokinet 41:999-1004. 2002
    ..To examine the pharmacokinetics of omeprazole during intravenous infusion in patients with varying degrees of liver dysfunction (Child-Pugh categories A to C)...
  5. ncbi request reprint Protective effect of superoxide dismutase in radiation-induced intestinal inflammation
    Meritxell Molla
    Department of Gastroenterology, Hospital Clinic, Institut de Investigacions Biomediques August Pi i Sunyer, Barcelona, Spain
    Int J Radiat Oncol Biol Phys 61:1159-66. 2005
    ..To analyze the therapeutic value of Cu/Zn-superoxide dismutase (SOD1) supplementation in an experimental model of radiation-induced intestinal inflammation and explore its mechanistic effects...
  6. ncbi request reprint Nitric oxide supplementation ameliorates dextran sulfate sodium-induced colitis in mice
    Azucena Salas
    Department of Gastroenterology, Institut de Malalties Digestives, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer IDIBAPS, Barcelona, Spain
    Lab Invest 82:597-607. 2002
    ..In conclusion, exogenous NO supplementation significantly ameliorates dextran sulfate sodium-induced colitis. This effect is related to a reduction in leukocyte recruitment and proinflammatory cytokine production...
  7. ncbi request reprint Anti-inflammatory effects of low-dose radiotherapy in an experimental model of systemic inflammation in mice
    Meritxell Arenas
    Department of Radiation Oncology, Hospital Clinic de Barcelona, Institut de Investigacions Biomèdiques August Pi i Sunyer IDIBAPS, University of Barcelona, Barcelona, Spain
    Int J Radiat Oncol Biol Phys 66:560-7. 2006
    ..The aim of this study was to determine the effects of low-dose radiotherapy (LD-RT) on the inflammatory response and to characterize the potential mechanisms underlying these effects...
  8. ncbi request reprint Superoxide dismutase ameliorates TNBS-induced colitis by reducing oxidative stress, adhesion molecule expression, and leukocyte recruitment into the inflamed intestine
    Joaquim Seguí
    Department of Gastroenterology, Hospital Clinic, IDIBAPS, Villarroel 170, 08036 Barcelona, Spain
    J Leukoc Biol 76:537-44. 2004
    ..This effect is related to a reduction in VCAM-1 expression and leukocyte recruitment into the inflamed intestine...
  9. ncbi request reprint Leukocyte recruitment in colon cancer: role of cell adhesion molecules, nitric oxide, and transforming growth factor beta1
    Xavier Bessa
    Gastroenterology Department, Institut de Malalties Digestives, Hospital Clinic, Institut d Investigacions Biomèdiques Agust Pi i Sunyer, University of Barcelona, Barcelona, Spain
    Gastroenterology 122:1122-32. 2002
    ..To characterize leukocyte-endothelium interaction in experimental colon cancer, quantify the main endothelial cell adhesion molecules (CAMs), and evaluate the effect of tumor-derived products...
  10. ncbi request reprint Effect of cyclosporin A on cell adhesion molecules and leukocyte-endothelial cell interactions in experimental colitis
    Antonio Soriano-Izquierdo
    Department of Gastroenterology, Institut de Malalties Digestives, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer IDIBAPS, University of Barcelona, Barcelona, Spain
    Inflamm Bowel Dis 10:789-800. 2004
    ..The aim of this study was to investigate whether modulation of leukocyte recruitment and expression of cell adhesion molecules contribute to the therapeutic efficacy of CsA in a model of experimental colitis...
  11. ncbi request reprint Endoscopic ultrasonography in patients with large gastric folds at endoscopy and biopsies negative for malignancy: predictors of malignant disease and clinical impact
    Angels Gines
    Endoscopy Unit, Department of Gastroenterology, Institut de Malalties Digestives i Metaboliques, Centre de Diagnòstic Biomèdic Hospital Clínic, IDIBAPS, Barcelona, Spain
    Am J Gastroenterol 101:64-9. 2006
    ....
  12. pmc Prognostic value of postoperative detection of blood circulating tumor cells in patients with colorectal cancer operated on for cure
    Xavier Bessa
    Department of Gastroenterology, Institut de Malalties Digestives, Hospital Clinic, IDIBAPS, University of Barcelona, Catalonia, Spain
    Ann Surg 237:368-75. 2003
    ..To assess whether postoperative detection of circulating tumor cells in peripheral blood influenced the prognosis of patients with colorectal cancer after radical surgery...
  13. ncbi request reprint Association of the ARLTS1 Cys148Arg variant with sporadic and familial colorectal cancer
    Sergi Castellvi-Bel
    Department of Gastroenterology, Institut de Malalties Digestives i Metaboliques, Hospital Clinic, CIBER EHD, IDIBAPS, Villarroel 170, 08036 Barcelona, Catalonia, Spain
    Carcinogenesis 28:1687-91. 2007
    ..23, P = 0.007) and familial cases and controls (OR = 1.55, 95% CI = 1.10-2.19, P = 0.01) in agreement with a hypothetical moderate increase of the cancer risk linked to the C148R ARLTS1 variant, both in sporadic and familial CRC cases...
  14. doi request reprint Genetic susceptibility variants associated with colorectal cancer prognosis
    Anna Abuli
    Department of Gastroenterology, Hospital Clinic, Centro de Investigacion Biomedica en Red de Enfermedades Hepaticas y Digestivas CIBERehd, Institut d Investigacions Biomediques August Pi i Sunyer IDIBAPS, University of Barcelona, Barcelona, Catalonia 08036, Spain
    Carcinogenesis 34:2286-91. 2013
    ....
  15. ncbi request reprint Life events and inflammatory bowel disease relapse: a prospective study of patients enrolled in remission
    Angela Vidal
    Department of Clinical Psychology, Hospital Clinic de Barcelona, Institute Investigacions Biomèdiques August Pi i Sunyer, Barcelona, Spain
    Am J Gastroenterol 101:775-81. 2006
    ....
  16. ncbi request reprint A prospective trial comparing wireless capsule endoscopy and barium contrast series for small-bowel surveillance in hereditary GI polyposis syndromes
    Alfredo Mata
    Digestive Endoscopy Unit, Gastroenterology Department, Institut de Malaties Digestives, Barcelona, Catalonia, Spain
    Gastrointest Endosc 61:721-5. 2005
    ..The objective was to establish the effectiveness of wireless capsule endoscopy for detecting small-bowel polyps in patients with hereditary GI polyposis syndromes in comparison with barium contrast series...
  17. ncbi request reprint Relative roles of ICAM-1 and VCAM-1 in the pathogenesis of experimental radiation-induced intestinal inflammation
    Meritxell Molla
    Department of Gastroenterology, Hospital Clinic, Institut de Investigacions Biomediques August Pi i Sunyer, University of Barcelona, Barcelona, Spain
    Int J Radiat Oncol Biol Phys 57:264-73. 2003
    ..Our objective was to characterize the requirement for intercellular adhesion molecule 1 (ICAM-1) and vascular cell adhesion molecule 1 (VCAM-1) in intestinal inflammatory response after abdominal irradiation...
  18. ncbi request reprint Detection of lymph node micrometastases by gene promoter hypermethylation in samples obtained by endosonography- guided fine-needle aspiration biopsy
    Maria Pellise
    Department of Gastroenterology, Institut de Malalties Digestives, Centre de Diagnostic Biomedic, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer, University of Barcelona, Barcelona, Catalonia, Spain
    Clin Cancer Res 10:4444-9. 2004
    ..Moreover, addition of methylation analysis to conventional cytology may increase its sensitivity at the expenses of a decrease in its specificity...
  19. ncbi request reprint Postoperative surveillance in patients with colorectal cancer who have undergone curative resection: a prospective, multicenter, randomized, controlled trial
    Francisco Rodriguez-Moranta
    Gastroenterology Department, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer, University of Barcelona IDIBAPS, Barcelona, Catalonia, Spain
    J Clin Oncol 24:386-93. 2006
    ..This prospective, multicenter, randomized, controlled trial was aimed at comparing the efficacy of two different surveillance strategies in terms of both survival and recurrence resectability...
  20. doi request reprint Susceptibility genetic variants associated with colorectal cancer risk correlate with cancer phenotype
    Anna Abuli
    Department of Gastroenterology, Hospital del Mar, Institut Municipal d Investigacio Medica, Pompeu Fabra University, Barcelona, Catalonia, Spain
    Gastroenterology 139:788-96, 796.e1-6. 2010
    ..Characterization of such a correlation would improve CRC management and prevention programs. We assessed the association between these genetic variants and CRC phenotype in patients and modeled pairwise combinations to detect epistasis...
  21. ncbi request reprint Down-regulation of endothelial adhesion molecules and leukocyte adhesion by treatment with superoxide dismutase is beneficial in chronic immune experimental colitis
    Joaquim Seguí
    Department of Gastroenterology, Hospital Clinic, Institut de Investigacions Biomèdiques August Pi i Sunyer IDIBAPS, University of Barcelona, Spain
    Inflamm Bowel Dis 11:872-82. 2005
    ..Down-regulation of adhesion molecule expression, reduction of lipid hydroperoxidation, and recruitment of leukocytes into the inflamed intestine contribute to this beneficial effect...
  22. ncbi request reprint ERCP in orthotopic liver transplanted patients
    Alfredo Mata
    Section of GI Endoscopy, Motility and Functional GI Tests, Institut de Malalties Digestives, Hospital Clinic, Barcelona, Spain
    Hepatogastroenterology 51:1801-4. 2004
    ..Biliary complications after orthotopic liver transplantation (OLT) are still common. The aim of the study was to assess the effectiveness of ERCP as a diagnostic and treatment tool in the management of biliary tract OLT complications...
  23. doi request reprint Health-related quality of life in inflammatory bowel disease patients: the role of psychopathology and personality
    Angela Vidal
    Department of Clinical Psychology, Hospital Clinic de Barcelona, CIBER EHD, Institut Investigacions Biomèdiques August Pi i Sunyer, Barcelona, Spain
    Inflamm Bowel Dis 14:977-83. 2008
    ....
  24. ncbi request reprint Late-occurring liver metastases in colorectal cancer
    Francisco Rodriguez-Moranta
    Gastroenterology Department, Institut de Malalties Digestives, Hospital Clinic, IDIBAPS, University of Barcelona, Barcelona, Catalonia, Spain
    Dig Dis Sci 50:345-7. 2005
  25. doi request reprint Susceptibility genetic variants associated with early-onset colorectal cancer
    María Dolores Giráldez
    Department of Gastroenterology, Hospital Clinic, Centro de Investigacion Biomedica en Red de Enfermedades Hepaticas y Digestivas CIBERehd, IDIBAPS, University of Barcelona, Villarroel 170, 08036 Barcelona, Catalonia, Spain
    Carcinogenesis 33:613-9. 2012
    ..Association of CRC susceptibility variants with some patient's familiar and personal features could be relevant for screening and surveillance strategies in this high-risk group and it should be explored in further studies...
  26. pmc Aberrant gene promoter methylation associated with sporadic multiple colorectal cancer
    Victoria Gonzalo
    Department of Gastroenterology, Hospital Clinic, Centro de Investigación Biomédica en Red en el Area temática de Enfermedades Hepáticas y Digestivas, Institut d Investigacions Biomediques August Pi i Sunyer, University of Barcelona, Barcelona, Catalonia, Spain
    PLoS ONE 5:e8777. 2010
    ....
  27. doi request reprint [The impact of anxiety and depression on relapse in patients with inflammatory bowel disease]
    Angela Vidal
    Servicio de Psicología Clínica, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer, Barcelona
    Med Clin (Barc) 132:298-302. 2009
    ..We sought to determine whether suffering anxiety and depressive disorders among patients with inactive disease would increase the risk of subsequent relapses...
  28. pmc Whole-exome sequencing identifies rare pathogenic variants in new predisposition genes for familial colorectal cancer
    Clara Esteban-Jurado
    Servei de Gastroenterologia, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas, University of Barcelona, Barcelona, Spain
    Genet Med 17:131-42. 2015
    ..The hypothesis of rare high-penetrance mutations in new genes is a likely explanation for the underlying predisposition in some of these familial cases...
  29. doi request reprint Seeking genetic susceptibility variants for colorectal cancer: the EPICOLON consortium experience
    Sergi Castellvi-Bel
    Department of Gastroenterology, Hospital Clinic, CIBERehd, IDIBAPS, University of Barcelona, Villarroel 170, 08036 Barcelona, Catalonia, Spain
    Mutagenesis 27:153-9. 2012
    ..Finishing their own pangenomic study and performing whole-exome sequencing in selected CRC samples are among EPICOLON future research prospects...
  30. pmc Case-control study for colorectal cancer genetic susceptibility in EPICOLON: previously identified variants and mucins
    Anna Abuli
    Department of Gastroenterology, IDIBAPS, Hospital Clinic, CIBERehd, University of Barcelona, Barcelona, Catalonia, Spain
    BMC Cancer 11:339. 2011
    ....
  31. doi request reprint [Prediction of prognosis of patients with pancreatic adenocarcinoma with curative intent resection by means of histologic grade and pathologic N stage]
    Antonio Soriano-Izquierdo
    Servicio de Gastroenterologia, Institut de Malalties Digestives i Metaboliques, Hospital Clínic Institut d Investigacions Biomèdiques August Pi i Sunyer IDIBAPS, CIBERehd Universidad de Barcelona, Barcelona, Espana
    Med Clin (Barc) 132:163-71. 2009
    ..We evaluated the prognostic significance of different factors in both overall survival and tumor recurrence in patients with pancreatic adenocarcinoma who had undergone pancreatic resection with curative intent...
  32. ncbi request reprint Risk assessment in relatives of gastric cancer patients: hyperproliferation, genetics, and Helicobacter pylori infection
    J Ignasi Elizalde
    Gastroenterology Department, Institut de Malalties Digestives i Metaboliques, Hospital Clinic, Universitat de Barcelona, IDIBAPS, Spain
    Eur J Gastroenterol Hepatol 18:877-9. 2006
    ..However, several lines of evidence suggest that the increased cancer risk in first-degree relatives of gastric cancer probands is mostly dependent on Helicobacter pylori infection clustering...
  33. doi request reprint Impact of wide-angle, high-definition endoscopy in the diagnosis of colorectal neoplasia: a randomized controlled trial
    Maria Pellise
    Gastroenterology Department, Endoscopy Unit, Institut de Malalties Digestives i Metaboliques, Hospital Clinic, CIBERehd, IDIBAPS, University of Barcelona, Barcelona, Spain
    Gastroenterology 135:1062-8. 2008
    ..We sought to compare the performance of colonoscopy using a high-definition, wide-angle endoscope (HDE) versus a standard colonoscope (SC) for the detection of colorectal neoplasia...
  34. ncbi request reprint Positive VEGF immunostaining independently predicts poor prognosis in curatively resected gastric cancer patients: results of a study assessing a panel of angiogenic markers
    Oscar Vidal
    Department of Surgery, Institut de Malalties Digestives i Metabolisme, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer IDIBAPS, University of Barcelona Medical School, Barcelona, Spain
    J Gastrointest Surg 12:1005-14. 2008
    ..001; HR, 3.27; 95% CI, 1.76 to 6.10) and tumor recurrence (p = 0.002; HR, 2.81; 95% CI, 1.48 to 5.35). Our study suggests that VEGF alone may be clinically useful for establishing therapeutic decisions in gastric cancer patients...
  35. ncbi request reprint Laparoscopy-assisted colectomy versus open colectomy for treatment of non-metastatic colon cancer: a randomised trial
    Antonio M Lacy
    Department of Surgery, Institut de Malalties Digestives, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer, University of Barcelona, 08036 Barcelona, Spain
    Lancet 359:2224-9. 2002
    ..Our study aimed to compare efficacy of LAC and open colectomy (OC) for treatment of non-metastatic colon cancer in terms of tumour recurrence and survival...
  36. pmc New genes emerging for colorectal cancer predisposition
    Clara Esteban-Jurado
    Clara Esteban Jurado, Anna Abulí, Jenifer Muñoz, Francesc Balaguer, Teresa Ocaña, Antoni Castells, Josep M Piqué, Sergi Castellví Bel, Department of Gastroenterology, Hospital Clinic, Centro de Investigacion Biomedica en Red de Enfermedades Hepaticas y Digestivas CIBERehd, Institut d Investigacions Biomediques August Pi i Sunyer IDIBAPS, University of Barcelona, 08036 Barcelona, Catalonia, Spain
    World J Gastroenterol 20:1961-71. 2014
    ..By using whole-genome sequencing, germline mutations in the POLE and POLD1 genes have been found to be responsible for a new form of CRC genetic predisposition called polymerase proofreading-associated polyposis...
  37. ncbi request reprint Evaluation of PARVG located on 22q13 as a candidate tumor suppressor gene for colorectal and breast cancer
    Sergi Castellvi-Bel
    Department of Gastroenterology, Institut de Malalties Digestives, Hospital Clinic, Barcelona, Catalonia, Spain
    Cancer Genet Cytogenet 144:80-2. 2003
    ..We have identified several DNA variants that are not compatible with pathogenic mutations. Accordingly, PARVG appears not to be a tumor suppressor gene involved in CRC and breast cancer development and progression...
  38. doi request reprint Transcriptional analysis of the intestinal mucosa of patients with ulcerative colitis in remission reveals lasting epithelial cell alterations
    Núria Planell
    Department of Gastroenterology, IDIBAPS, Hospital Clinic, CIBER EHD, Barcelona, Spain
    Gut 62:967-76. 2013
    ..Ulcerative colitis (UC) is a chronic condition characterised by the relapsing inflammation despite previous endoscopic and histological healing. Our objective was to identify the molecular signature associated with UC remission...
  39. ncbi request reprint Endoscopic requirements of colorectal cancer screening programs in average-risk population. Estimation according to a Markov model
    Francisco Rodriguez-Moranta
    Department of Gastroenterology, Institut de Malalties Digestives i Metaboliques, Hospital Clinic, Barcelona, Spain
    Gastroenterol Hepatol 31:405-12. 2008
    ..To estimate endoscopic requirements of four different CRC screening strategies (annual and biennial fecal occult blood testing (FOBT), flexible sigmoidoscopy every 5 years, and colonoscopy every 10 years) in an average-risk population...
  40. ncbi request reprint [Usefulness of tomographic computer colonography for colorectal polyp detection]
    Virginia Piñol
    Servicio de Gastroenterologia, Instituto de Enfermedades Digestivas, Institut d Investigacions Biomediques August Pi i Sunyer IDIBAPS, Universitat de Barcelona, Barcelona, Spain
    Med Clin (Barc) 123:41-4. 2004
    ..The aim of the present study was to evaluate the efficacy of CTC in the detection of colorectal polyps, and to establish the factors determining a diagnostic accuracy...
  41. ncbi request reprint Time course of anti-inflammatory effect of low-dose radiotherapy: correlation with TGF-beta(1) expression
    Meritxell Arenas
    Department of Radiation Oncology, Hospital Clinic de Barcelona, University of Barcelona, Spain
    Radiother Oncol 86:399-406. 2008
    ..The objectives of this study were to characterize the in vivo effects of LD-RT on leukocyte recruitment over time, and its relationship with TGF-beta(1) production...
  42. doi request reprint Defective IL-10 production in severe phenotypes of Crohn's disease
    Ismael Correa
    Department of Gastroenterology, Hospital Clinic, IDIBAPS, Barcelona, Spain
    J Leukoc Biol 85:896-903. 2009
    ..We propose that treatment with IL-10 or IL-10-inducing therapies could be of particular benefit to these group of patients...
  43. pmc Crohn's disease patients carrying Nod2/CARD15 gene variants have an increased and early need for first surgery due to stricturing disease and higher rate of surgical recurrence
    Manuel Alvarez-Lobos
    Department of Gastroenterology, Hospital Clinic, Barcelona, Spain
    Ann Surg 242:693-700. 2005
    ..To study the predictive value of Nod2/CARD15 gene variants along with disease phenotypic characteristics for requirement of initial surgery and for surgical recurrence in Crohn's disease (CD)...
  44. ncbi request reprint Cyclooxygenase 2 expression in colorectal cancer with DNA mismatch repair deficiency
    Antoni Castells
    Department of Gastroenterology, Institut de Malalties Digestives, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer, University of Barcelona
    Clin Cancer Res 12:1686-92. 2006
    ....
  45. ncbi request reprint GI flexible endoscope disinfection: "in use" test comparative study
    Josep M Bordas
    GI Endoscopy, Motility and Functional Tests, Institut de Malalties Digestives, Institut Malalties Digestives, Hospital Clinic, Facultat de Medicina Universitat de Barcelona, Barcelona, Spain
    Hepatogastroenterology 52:800-7. 2005
    ..The "in use" method is adequate for control and for establishing comparisons between different disinfectants...
  46. ncbi request reprint [High-grade dysplasia as a risk factor of metachronous advanced colorectal neoplasms in patients with advanced adenomas]
    Antonio Z Gimeno-Garcia
    Servicio de Gastroenterologia, Institut de Malalties Digestives, Hospital Clinic, Universitat de Barcelona, Barcelona, Espana
    Gastroenterol Hepatol 30:207-11. 2007
    ..High grade dysplasia (HGD) is the main marker of cancer transformation. However, its predictive value for developing advanced neoplams in patients with advanced adenoma is unknown...
  47. ncbi request reprint Effects of Helicobacter pylori eradication on platelet activation and disease recurrence in patients with acute coronary syndromes
    J Ignasi Elizalde
    Gastroenterology Department, Institut Clinic de Malalties Digestives, University of Barcelona, Barcelona, Spain
    Helicobacter 9:681-9. 2004
    ..Platelet activation is consistently observed in animal models of Helicobacter pylori infection and could help to explain the alleged epidemiological association between H. pylori and coronary heart disease...
  48. doi request reprint The long-term results of a randomized clinical trial of laparoscopy-assisted versus open surgery for colon cancer
    Antonio M Lacy
    Department of Surgery, Centro de Investigaciones Biomédicas Esther Koplowitz, IMDiM, IDIBAPS, Hospital Clinic, University of Barcelona, Spain
    Ann Surg 248:1-7. 2008
    ..The aim of this study was to compare the long-term outcome of laparoscopy-assisted colectomy (LAC) and open colectomy (OC) for nonmetastatic colon cancer...
  49. ncbi request reprint Endoscopic ultrasound-guided fine needle aspiration: predictive factors of accurate diagnosis and cost-minimization analysis of on-site pathologist
    Maria Pellisé Urquiza
    Department of Gastroenterology, Hospital Clinic, Barcelona, Spain
    Gastroenterol Hepatol 30:319-24. 2007
    ....
  50. pmc The MLH1 c.1852_1853delinsGC (p.K618A) variant in colorectal cancer: genetic association study in 18,723 individuals
    Anna Abuli
    Department of Gastroenterology, Hospital Clinic, Centro de Investigacion Biomedica en Red de Enfermedades Hepaticas y Digestivas CIBERehd, Institut d Investigacions Biomediques August Pi i Sunyer IDIBAPS, University of Barcelona, Barcelona, Catalonia, Spain Department of Gastroenterology, Hospital del Mar IMIM Hospital del Mar Medical Research Centre, Pompeu Fabra University, Barcelona, Catalonia, Spain
    PLoS ONE 9:e95022. 2014
    ....
  51. ncbi request reprint [Implementation of clinical management in hospital organization]
    David Font
    Institut d Investigacions Biomediques August Pi i Sunyer, Hospital Clinic, Universitat de Barcelona, Barcelona, Espana
    Med Clin (Barc) 130:351-6. 2008
  52. ncbi request reprint Psychometric properties of the original Inflammatory Bowel Disease Questionnaire, a Spanish version
    Angela Vidal
    Department of Clinical Psychology, Hospital Clinic de Barcelona, Institut Investigacions Biomèdiques August Pi i Sunyer, Barcelona, Spain
    Gastroenterol Hepatol 30:212-8. 2007
    ....
  53. ncbi request reprint [Organization and functioning model of biomedical research structures. Situation and future challenges]
    David Font
    Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer, Universitat de Barcelona, Barcelona, Espana
    Med Clin (Barc) 130:510-6. 2008
  54. ncbi request reprint Identification of MYH mutation carriers in colorectal cancer: a multicenter, case-control, population-based study
    Francesc Balaguer
    Department of Gastroenterology, Institut de Malalties Digestives i Metaboliques, Hospital Clinic, CIBERehd, IDIBAPS Institut d Investigacions Biomèdiques August Pi i Sunyer, University of Barcelona, Barcelona, Catalonia, Spain
    Clin Gastroenterol Hepatol 5:379-87. 2007
    ....
  55. ncbi request reprint Efficacy of an inhibitor of adhesion molecule expression (GI270384X) in the treatment of experimental colitis
    Julian Panes
    Dept of Gastroenterology, Hospital Clinic, Villarroel 170, Barcelona 08036, Spain
    Am J Physiol Gastrointest Liver Physiol 293:G739-48. 2007
    ..Reduced adhesion molecule expression and leukocyte recruitment to the inflamed intestine contribute to this beneficial effect...
  56. ncbi request reprint The role of P-selectin in experimental colitis as determined by antibody immunoblockade and genetically deficient mice
    Meritxell Gironella
    Department of Gastroenterology, Institut de Malalties Digestives, IIBB CSIC, Institut d Investigacions Biomediques August Pi i Sunyer IDIBAPS, University of Barcelona, Villaroel 170, 08036 Barcelona, Spain
    J Leukoc Biol 72:56-64. 2002
    ..Therefore, ablation of P-selectin function ameliorates colitis, but this protection is attenuated in P-selectin(-/-) mice, probably due to compensatory mechanisms that involve up-regulation of other adhesion molecules such as VCAM-1...