Jose Perez-Martin

Summary

Country: Spain

Publications

  1. pmc Dikaryotic cell cycle in the phytopathogenic fungus Ustilago maydis is controlled by the DNA damage response cascade
    Jose Perez-Martin
    Departamento de Biotecnologia Microbiana, Centro Nacional de Biotecnologia CSIC, Madrid, Spain
    Plant Signal Behav 6:1574-7. 2011
  2. doi DNA-damage response in the basidiomycete fungus Ustilago maydis relies in a sole Chk1-like kinase
    Jose Perez-Martin
    Departamento de Biotecnologia Microbiana, Centro Nacional de Biotecnologia CSIC, Campus de Cantoblanco UAM, 28049 Madrid, Spain
    DNA Repair (Amst) 8:720-31. 2009
  3. ncbi Inhibitory phosphorylation of a mitotic cyclin-dependent kinase regulates the morphogenesis, cell size and virulence of the smut fungus Ustilago maydis
    Cecilia Sgarlata
    Department of Microbial Biotechnology, Centro Nacional de Biotecnologia CSIC, Campus de Cantoblanco UAM, 28049 Madrid, Spain
    J Cell Sci 118:3607-22. 2005
  4. ncbi A member of the Fizzy-related family of APC activators is regulated by cAMP and is required at different stages of plant infection by Ustilago maydis
    Sonia Castillo-Lluva
    Department of Microbial Biotechnology, Centro Nacional de Biotecnologia CSIC, Campus de Cantoblanco UAM, 28049 Madrid, Spain
    J Cell Sci 117:4143-56. 2004
  5. ncbi The crk1 gene encodes an Ime2-related protein that is required for morphogenesis in the plant pathogen Ustilago maydis
    Elia Garrido
    Department of Microbial Biotechnology, Centro Nacional de Biotecnologia CSIC, Campus de Cantoblanco UAM, 28049 Madrid, Spain
    Mol Microbiol 47:729-43. 2003
  6. ncbi Sustained cell polarity and virulence in the phytopathogenic fungus Ustilago maydis depends on an essential cyclin-dependent kinase from the Cdk5/Pho85 family
    Sonia Castillo-Lluva
    Departamento de Biotecnologia Microbiana, Centro Nacional de Biotecnologia CSIC, 28049 Madrid, Spain
    J Cell Sci 120:1584-95. 2007
  7. pmc The induction of sexual development and virulence in the smut fungus Ustilago maydis depends on Crk1, a novel MAPK protein
    Elia Garrido
    Departamento de Biotecnologia Microbiana, Centro Nacional de Biotecnologia CSIC, Campus de Cantoblanco UAM, 28049 Madrid, Spain
    Genes Dev 18:3117-30. 2004
  8. pmc The DNA damage response signaling cascade regulates proliferation of the phytopathogenic fungus Ustilago maydis in planta
    Carmen de Sena-Tomás
    Departamento de Biotecnologia Microbiana, Centro Nacional de Biotecnologia, Consejo Superior de Investigaciones Cientificas, 28049 Madrid, Spain
    Plant Cell 23:1654-65. 2011
  9. doi A role for the DNA-damage checkpoint kinase Chk1 in the virulence program of the fungus Ustilago maydis
    Natalia Mielnichuk
    Departamento de Biotecnologia Microbiana, Centro Nacional de Biotecnologia CSIC, Campus de Cantoblanco UAM, 28049 Madrid, Spain
    J Cell Sci 122:4130-40. 2009
  10. pmc Biz1, a zinc finger protein required for plant invasion by Ustilago maydis, regulates the levels of a mitotic cyclin
    Ignacio Flor-Parra
    Departamento de Biotecnologia Microbiana, Centro Nacional de Biotecnologia, Consejo Superior de Investigaciones Cientificas, Campus de Cantoblanco, Universidad Autonoma de Madrid, 28049 Madrid, Spain
    Plant Cell 18:2369-87. 2006

Collaborators

  • Gero Steinberg
  • David Canovas
  • Isabel Alvarez-Tabarés
  • Regine Kahmann
  • Sonia Castillo-Lluva
  • Cecilia Sgarlata
  • Natalia Carbó
  • Natalia Mielnichuk
  • Tatiana Garcia-Muse
  • Ignacio Flor-Parra
  • Elia Garrido
  • Carmen de Sena-Tomás
  • Cristina Sánchez-Martinez
  • William K Holloman
  • Alfonso Fernández-Alvarez
  • Isabella Weber
  • Jörg Kämper
  • Miroslav Vranes
  • Ute Voss
  • Philip Muller

Detail Information

Publications23

  1. pmc Dikaryotic cell cycle in the phytopathogenic fungus Ustilago maydis is controlled by the DNA damage response cascade
    Jose Perez-Martin
    Departamento de Biotecnologia Microbiana, Centro Nacional de Biotecnologia CSIC, Madrid, Spain
    Plant Signal Behav 6:1574-7. 2011
    ..Here we propose and discuss several hypothesis to address these questions...
  2. doi DNA-damage response in the basidiomycete fungus Ustilago maydis relies in a sole Chk1-like kinase
    Jose Perez-Martin
    Departamento de Biotecnologia Microbiana, Centro Nacional de Biotecnologia CSIC, Campus de Cantoblanco UAM, 28049 Madrid, Spain
    DNA Repair (Amst) 8:720-31. 2009
    ..maydis the sole Chk1 kinase recapitulates the roles that in other organisms are shared by Chk1 and the Chk2/Rad53 family of protein kinases...
  3. ncbi Inhibitory phosphorylation of a mitotic cyclin-dependent kinase regulates the morphogenesis, cell size and virulence of the smut fungus Ustilago maydis
    Cecilia Sgarlata
    Department of Microbial Biotechnology, Centro Nacional de Biotecnologia CSIC, Campus de Cantoblanco UAM, 28049 Madrid, Spain
    J Cell Sci 118:3607-22. 2005
    ..These data reinforces the connections between cell cycle, morphogenesis and virulence in this smut fungus...
  4. ncbi A member of the Fizzy-related family of APC activators is regulated by cAMP and is required at different stages of plant infection by Ustilago maydis
    Sonia Castillo-Lluva
    Department of Microbial Biotechnology, Centro Nacional de Biotecnologia CSIC, Campus de Cantoblanco UAM, 28049 Madrid, Spain
    J Cell Sci 117:4143-56. 2004
    ..maydis. We propose that along the infection process, Cru1 is required to keep the appropriate G1 length necessary for the adaptation of fungal cells to host environment through the different stages of the plant infection...
  5. ncbi The crk1 gene encodes an Ime2-related protein that is required for morphogenesis in the plant pathogen Ustilago maydis
    Elia Garrido
    Department of Microbial Biotechnology, Centro Nacional de Biotecnologia CSIC, Campus de Cantoblanco UAM, 28049 Madrid, Spain
    Mol Microbiol 47:729-43. 2003
    ..These results demonstrate an important role for the crk1- encoded protein in the morphogenesis and environmental adaptation in Ustilago maydis...
  6. ncbi Sustained cell polarity and virulence in the phytopathogenic fungus Ustilago maydis depends on an essential cyclin-dependent kinase from the Cdk5/Pho85 family
    Sonia Castillo-Lluva
    Departamento de Biotecnologia Microbiana, Centro Nacional de Biotecnologia CSIC, 28049 Madrid, Spain
    J Cell Sci 120:1584-95. 2007
    ..These results support a major role for morphogenesis in the virulence program of dimorphic fungi...
  7. pmc The induction of sexual development and virulence in the smut fungus Ustilago maydis depends on Crk1, a novel MAPK protein
    Elia Garrido
    Departamento de Biotecnologia Microbiana, Centro Nacional de Biotecnologia CSIC, Campus de Cantoblanco UAM, 28049 Madrid, Spain
    Genes Dev 18:3117-30. 2004
    ..On the basis of our data, we propose that all of these proteins constitute a new family of MAP kinases...
  8. pmc The DNA damage response signaling cascade regulates proliferation of the phytopathogenic fungus Ustilago maydis in planta
    Carmen de Sena-Tomás
    Departamento de Biotecnologia Microbiana, Centro Nacional de Biotecnologia, Consejo Superior de Investigaciones Cientificas, 28049 Madrid, Spain
    Plant Cell 23:1654-65. 2011
    ..Therefore, Chk1 and Atr1 emerge as critical cell type regulators in addition to their roles in the DNA damage response...
  9. doi A role for the DNA-damage checkpoint kinase Chk1 in the virulence program of the fungus Ustilago maydis
    Natalia Mielnichuk
    Departamento de Biotecnologia Microbiana, Centro Nacional de Biotecnologia CSIC, Campus de Cantoblanco UAM, 28049 Madrid, Spain
    J Cell Sci 122:4130-40. 2009
    ..Our results support the emerging idea that checkpoint kinases have roles other than in the DNA-damage response, by virtue of their ability to interact with the cell cycle machinery...
  10. pmc Biz1, a zinc finger protein required for plant invasion by Ustilago maydis, regulates the levels of a mitotic cyclin
    Ignacio Flor-Parra
    Departamento de Biotecnologia Microbiana, Centro Nacional de Biotecnologia, Consejo Superior de Investigaciones Cientificas, Campus de Cantoblanco, Universidad Autonoma de Madrid, 28049 Madrid, Spain
    Plant Cell 18:2369-87. 2006
    ..Our data support a model in which Biz1 is involved in cell cycle arrest preceding plant penetration as well as in the induction of appressoria...
  11. ncbi The cdc25 phosphatase is essential for the G2/M phase transition in the basidiomycete yeast Ustilago maydis
    Cecilia Sgarlata
    Department of Microbial Biotechnology, Centro Nacional de Biotecnologia CSIC, Campus de Cantoblanco UAM, 28049 Madrid, Spain
    Mol Microbiol 58:1482-96. 2005
    ..maydis Cdc25 counteracts the Wee1-mediated inhibitory phosphorylation of Cdk1-Clb2 complex. Our results supports a model in which inhibitory phosphorylation of Cdk1 is a primary mechanism operating at G2/M transition in this fungus...
  12. pmc Septins from the phytopathogenic fungus Ustilago maydis are required for proper morphogenesis but dispensable for virulence
    Isabel Alvarez-Tabarés
    Departamento de Biotecnologia Microbiana, Centro Nacional de Biotecnologia CSIC, Madrid, Spain
    PLoS ONE 5:e12933. 2010
    ..Studies of septins in fungal cells underpin a clear correlation between septin-based structures and fungal morphology, providing clues to understand the molecular frame behind the varied morphologies found in fungal world...
  13. ncbi Pathocycles: Ustilago maydis as a model to study the relationships between cell cycle and virulence in pathogenic fungi
    Jose Perez-Martin
    Departamento de Biotecnologia Microbiana, Centro Nacional de Biotecnologia CSIC, Campus de Cantoblanco UAM, 28049, Madrid, Spain
    Mol Genet Genomics 276:211-29. 2006
    ..maydis. We also discuss the connection between cell cycle and virulence and how cell cycle control is an important downstream target in the fungus-plant interaction...
  14. pmc Activation of the cell wall integrity pathway promotes escape from G2 in the fungus Ustilago maydis
    Natalia Carbó
    Department of Microbial Biotechnology, National Center of Biotechnology, Consejo Superior de Investigaciones Cientificas, Madrid, Spain
    PLoS Genet 6:e1001009. 2010
    ....
  15. pmc Pheromone-induced G2 arrest in the phytopathogenic fungus Ustilago maydis
    Tatiana Garcia-Muse
    Department of Microbial Biotechnology, Centro Nacional de Biotecnologia CSIC, Campus de Cantoblanco UAM, 28049 Madrid, Spain
    Eukaryot Cell 2:494-500. 2003
    ..Visualization of the nucleus and microtubule organization indicates that the arrest takes place at the G(2) phase. Chemical-induced cell cycle arrest and release in the presence of pheromone further support this conclusion...
  16. doi Cdk5 kinase regulates the association between adaptor protein Bem1 and GEF Cdc24 in the fungus Ustilago maydis
    Isabel Alvarez-Tabarés
    Departamento de Biotecnologia Microbiana, Centro Nacional de Biotecnologia CSIC, 28049 Madrid, Spain
    J Cell Sci 121:2824-32. 2008
    ..maydis. We found that Bem1 and Cdc24 physically interact and colocalize at cell tips and that Cdk5 regulates this interaction. Our data suggest a method by which Cdk5 could regulate polar growth in this phytopathogenic fungus...
  17. pmc The induction of the mating program in the phytopathogen Ustilago maydis is controlled by a G1 cyclin
    Sonia Castillo-Lluva
    Department of Microbial Biotechnology, Centro Nacional de Biotecnologia, Consejo Superior de Investigaciones Cientificas, Campus de Cantoblanco, Universidad Autonoma de Madrid, Spain
    Plant Cell 17:3544-60. 2005
    ..maydis...
  18. ncbi Characterization of B-type cyclins in the smut fungus Ustilago maydis: roles in morphogenesis and pathogenicity
    Tatiana Garcia-Muse
    Department of Microbial Biotechnology, Centro Nacional de Biotecnologia CSIC, Campus de Cantoblanco UAM, 28049 Madrid, Spain
    J Cell Sci 117:487-506. 2004
    ..Mutant strains with half a dose of clb2 or high level of clb2 expression are impaired at distinct stages in the infection process. These data reinforces the connections between cell cycle, morphogenesis and virulence in this smut fungus...
  19. doi 14-3-3 regulates the G2/M transition in the basidiomycete Ustilago maydis
    Natalia Mielnichuk
    Departamento de Biotecnologia Microbiana, Centro Nacional de Biotecnologia CSIC, Darwin 3, Campus de Cantoblanco UAM, 28049 Madrid, Spain
    Fungal Genet Biol 45:1206-15. 2008
    ..Comparison of the roles of 14-3-3 during cell cycle regulation in other fungal system let us to discuss the connections between morphogenesis, cell cycle regulation and the evolutionary role of 14-3-3 proteins in fungi...
  20. doi Spa2 is required for morphogenesis but it is dispensable for pathogenicity in the phytopathogenic fungus Ustilago maydis
    Natalia Carbó
    Departamento de Biotecnologia Microbiana, Centro Nacional de Biotecnologia CSIC, Madrid, Spain
    Fungal Genet Biol 45:1315-27. 2008
    ..Finally, to our surprise, we found that cells defectives in Spa2 function were as pathogenic as wild-type cells...
  21. pmc Polar growth in the infectious hyphae of the phytopathogen ustilago maydis depends on a virulence-specific cyclin
    Ignacio Flor-Parra
    Departamento de Biotecnologia Microbiana, Centro Nacional de Biotecnologia, Consejo Superior de Investigaciones Cientificas, Universidad Autonoma de Madrid, 28049 Madrid, Spain
    Plant Cell 19:3280-96. 2007
    ..However, in spite of this pivotal role during morphogenesis, pcl12 mutants were virulent. We discuss the implications of these results for the role of polar growth during the infection process...
  22. pmc Gpa2, a G-protein alpha subunit required for hyphal development in Candida albicans
    Cristina Sánchez-Martinez
    Department of Microbial Biotechnology, Centro Nacional de Biotecnologia CSIC, Campus de Cantoblanco UAM, 28049 Madrid, Spain
    Eukaryot Cell 1:865-74. 2002
    ..albicans genetic backgrounds. Our results indicate that, in response to environmental cues, Gpa2 is required for the regulation of a MAPK signaling pathway...
  23. doi Sphingolipid biosynthesis is required for polar growth in the dimorphic phytopathogen Ustilago maydis
    David Canovas
    Departamento de Biotecnologia Microbiana, Centro Nacional de Biotecnologia CSIC, Madrid, Spain
    Fungal Genet Biol 46:190-200. 2009
    ..Time course experiments suggest that AbA provokes cell depolarization in three steps: disassembly of SRDs from the tips, delocalization of some polarity proteins, and lastly appearance of medial division septa...