Javier Moreno

Summary

Country: Spain

Publications

  1. ncbi Changing views on Langerhans cell functions in leishmaniasis
    Javier Moreno
    Centro de Investigaciones Biologicas, Consejo Superior de Investigaciones Cientificas, Ramiro de Maeztu 9, 28040 Madrid, Spain
    Trends Parasitol 23:86-8. 2007
  2. pmc Immunization with H1, HASPB1 and MML Leishmania proteins in a vaccine trial against experimental canine leishmaniasis
    J Moreno
    WHO Collaborating Centre for Leishmaniasis, Centro Nacional de Microbiologia, Instituto de Salud Carlos III, Majadahonda, Spain
    Vaccine 25:5290-300. 2007
  3. pmc Factors associated with Leishmania asymptomatic infection: results from a cross-sectional survey in highland northern Ethiopia
    Estefanía Custodio
    Centro Nacional de Medicina Tropical, Instituto de Salud Carlos III, Madrid, Spain
    PLoS Negl Trop Dis 6:e1813. 2012
  4. doi Immunogenicity of HSP-70, KMP-11 and PFR-2 leishmanial antigens in the experimental model of canine visceral leishmaniasis
    Eugenia Carrillo
    WHO Collaborating Centre for Leishmaniasis, Centro Nacional de Microbiologia, Inst de Salud Carlos III, Majadahonda, Spain
    Vaccine 26:1902-11. 2008
  5. pmc Knowledge, attitudes and practices related to visceral leishmaniasis in rural communities of Amhara State: a longitudinal study in northwest Ethiopia
    Noemí López-Perea
    Centro Nacional de Epidemiologia, Instituto de Salud Carlos III, Madrid, Spain
    PLoS Negl Trop Dis 8:e2799. 2014
  6. ncbi Canine leishmaniasis
    Jorge Alvar
    WHO Collaborating Centre for Leishmaniasis, Servicio de Parasitologia, Centro Nacional de Microbiologia, Instituto de Salud Carlos III, 28220 Majadahonda, Madrid, Spain
    Adv Parasitol 57:1-88. 2004
  7. doi Cytokine profiles in canine visceral leishmaniasis
    Eugenia Carrillo
    Centro de Investigaciones Biologicas, Consejo Superior de Investigaciones Cientificas CSIC, C Ramiro de Maeztu 9, 28040 Madrid, Spain
    Vet Immunol Immunopathol 128:67-70. 2009
  8. ncbi Leishmania/HIV co-infections in the second decade
    Israel Cruz
    WHO Collaborating Centre for Leishmaniasis, National Centre of Microbiology, Institute of Health Carlos III, Madrid, Spain
    Indian J Med Res 123:357-88. 2006
  9. doi What is responsible for a large and unusual outbreak of leishmaniasis in Madrid?
    Eugenia Carrillo
    WHO Collaborating Centre for Leishmaniasis, Servicio de Parasitologia, Centro Nacional de Microbiologia, Instituto de Salud Carlos III, Ctra Majadahonda Pozuelo, Km 2, 2, 28220 Madrid, Spain
    Trends Parasitol 29:579-80. 2013
  10. doi Primary vaccination with the LiESP/QA-21 vaccine (CaniLeish) produces a cell-mediated immune response which is still present 1 year later
    Javier Moreno
    WHO Collaborating Centre for Leishmaniasis, Centro Nacional de Microbiologia, Instituto de Carlos III, Madrid, Spain
    Vet Immunol Immunopathol 158:199-207. 2014

Collaborators

Detail Information

Publications23

  1. ncbi Changing views on Langerhans cell functions in leishmaniasis
    Javier Moreno
    Centro de Investigaciones Biologicas, Consejo Superior de Investigaciones Cientificas, Ramiro de Maeztu 9, 28040 Madrid, Spain
    Trends Parasitol 23:86-8. 2007
    ..In their article, they propose a new role for epidermal Langerhans cells and dermal dendritic cells to explain the events that take place after inoculation by Leishmania...
  2. pmc Immunization with H1, HASPB1 and MML Leishmania proteins in a vaccine trial against experimental canine leishmaniasis
    J Moreno
    WHO Collaborating Centre for Leishmaniasis, Centro Nacional de Microbiologia, Instituto de Salud Carlos III, Majadahonda, Spain
    Vaccine 25:5290-300. 2007
    ..The results demonstrate that HASPB1 and H1 antigens in combination with Montanide were able to induce partial protection against canine leishmaniasis, even under extreme experimental challenge conditions...
  3. pmc Factors associated with Leishmania asymptomatic infection: results from a cross-sectional survey in highland northern Ethiopia
    Estefanía Custodio
    Centro Nacional de Medicina Tropical, Instituto de Salud Carlos III, Madrid, Spain
    PLoS Negl Trop Dis 6:e1813. 2012
    ..In order to develop effective control strategies on the transmission of the disease it is important to generate knowledge on the epidemiological determinants of the infection...
  4. doi Immunogenicity of HSP-70, KMP-11 and PFR-2 leishmanial antigens in the experimental model of canine visceral leishmaniasis
    Eugenia Carrillo
    WHO Collaborating Centre for Leishmaniasis, Centro Nacional de Microbiologia, Inst de Salud Carlos III, Majadahonda, Spain
    Vaccine 26:1902-11. 2008
    ..The identification as vaccine candidates of Leishmania antigens that elicit appropriate immune responses in the canine model is a key step in the rational approach to generate a vaccine for canine visceral leishmaniasis...
  5. pmc Knowledge, attitudes and practices related to visceral leishmaniasis in rural communities of Amhara State: a longitudinal study in northwest Ethiopia
    Noemí López-Perea
    Centro Nacional de Epidemiologia, Instituto de Salud Carlos III, Madrid, Spain
    PLoS Negl Trop Dis 8:e2799. 2014
    ..The knowledge on how the population perceives the disease is essential in order to propose successful control strategies...
  6. ncbi Canine leishmaniasis
    Jorge Alvar
    WHO Collaborating Centre for Leishmaniasis, Servicio de Parasitologia, Centro Nacional de Microbiologia, Instituto de Salud Carlos III, 28220 Majadahonda, Madrid, Spain
    Adv Parasitol 57:1-88. 2004
    ....
  7. doi Cytokine profiles in canine visceral leishmaniasis
    Eugenia Carrillo
    Centro de Investigaciones Biologicas, Consejo Superior de Investigaciones Cientificas CSIC, C Ramiro de Maeztu 9, 28040 Madrid, Spain
    Vet Immunol Immunopathol 128:67-70. 2009
    ..This review focuses on advances in the canine immune response knowledge over the recent years and examines the principal role of the cytokine pattern elicited after infection with L. infantum...
  8. ncbi Leishmania/HIV co-infections in the second decade
    Israel Cruz
    WHO Collaborating Centre for Leishmaniasis, National Centre of Microbiology, Institute of Health Carlos III, Madrid, Spain
    Indian J Med Res 123:357-88. 2006
    ..An extensive review of the literature on Leishmania/HIV co-infection has allowed the inclusion of a comprehensive and updated list of bibliographical references...
  9. doi What is responsible for a large and unusual outbreak of leishmaniasis in Madrid?
    Eugenia Carrillo
    WHO Collaborating Centre for Leishmaniasis, Servicio de Parasitologia, Centro Nacional de Microbiologia, Instituto de Salud Carlos III, Ctra Majadahonda Pozuelo, Km 2, 2, 28220 Madrid, Spain
    Trends Parasitol 29:579-80. 2013
    ..Although dogs are the main reservoir host, hares are suspected as a potential culprit for the surprising increase of cases. ..
  10. doi Primary vaccination with the LiESP/QA-21 vaccine (CaniLeish) produces a cell-mediated immune response which is still present 1 year later
    Javier Moreno
    WHO Collaborating Centre for Leishmaniasis, Centro Nacional de Microbiologia, Instituto de Carlos III, Madrid, Spain
    Vet Immunol Immunopathol 158:199-207. 2014
    ..These results confirm that vaccination with LiESP/QA-21 is capable of inducing an appropriate Th1-dominated immune profile which persists for a full year. ..
  11. ncbi Semi-quantitative analysis of cytokine expression in asymptomatic canine leishmaniasis
    Cristina Chamizo
    WHO Collaborating Centre for Leishmaniasis, Parasitology Service, National Centre of Microbiology, Instituto de Salud Carlos III, Madrid, Spain
    Vet Immunol Immunopathol 103:67-75. 2005
    ..Although both Th1 and Th2 cytokines are produced, cell mediated immunity observed in these L. infantum-infected asymptomatic dogs depended on the preferential expression of Th1 cytokines...
  12. pmc Use of a LiESP/QA-21 vaccine (CaniLeish) stimulates an appropriate Th1-dominated cell-mediated immune response in dogs
    Javier Moreno
    WHO Collaborating Centre for Leishmaniasis, Centro Nacional de Microbiologia, Instituto de Carlos III, Madrid, Spain
    PLoS Negl Trop Dis 6:e1683. 2012
    ....
  13. doi An approach for interlaboratory comparison of conventional and real-time PCR assays for diagnosis of human leishmaniasis
    Israel Cruz
    WHO Collaborating Center for Leishmaniasis, Servicio de Parasitologia, Centro Nacional de Microbiologia, Instituto de Salud Carlos III, Ctra Majadahonda Pozuelo, Km2, 28220 Madrid, Spain
    Exp Parasitol 134:281-9. 2013
    ....
  14. pmc Low prevalence of Leishmania infection in post-epidemic areas of Libo Kemkem, Ethiopia
    Luis Sordo
    Centro Nacional de Epidemiologia, Instituto de Salud Carlos III, CIBER en Epidemiología y Salud Pública CIBERESP, Madrid, Spain
    Am J Trop Med Hyg 86:955-8. 2012
    ..Only one case of active disease was encountered. The results suggest that the conditions responsible for the outbreak no longer reign. However, active surveillance remains necessary...
  15. ncbi Virulence and disease in leishmaniasis: what is relevant for the patient?
    Luis Rivas
    Centro de Investigaciones Biologicas, Consejo Superior de Investigaciones Cientificas CSIC, Ramiro de Maeztu 9, 28040 Madrid, Spain
    Trends Parasitol 20:297-301. 2004
  16. pmc Cytokine Release Assays as Tests for Exposure to Leishmania, and for Confirming Cure from Leishmaniasis, in Solid Organ Transplant Recipients
    Eugenia Carrillo
    WHO Collaborating Centre for Leishmaniasis, Centro Nacional de Microbiologia, Instituto de Salud Carlos III, Madrid, Spain
    PLoS Negl Trop Dis 9:e0004179. 2015
    ....
  17. ncbi A recombinant enolase from Anisakis simplex is differentially recognized in natural human and mouse experimental infections
    Esperanza Rodríguez
    Servicio de Parasitologia, Centro Nacional de Microbiologia, Instituto de Salud Carlos III, Ctra Majadahonda Pozuelo km 2, 2, 28220 Majadahonda, Madrid, Spain
    Med Microbiol Immunol 195:1-10. 2006
    ..These results seem to indicate that, during natural infection in humans, A. simplex larvae do not offer sufficient antigenic stimulus to induce anti-enolase antibodies...
  18. ncbi Canine leishmaniasis: epidemiological risk and the experimental model
    Javier Moreno
    WHO Collaborating Centre for Leishmaniasis, Servicio de Parasitologi a, Centro Nacional de Microbiologia, Instituto de Salud Carlos III, Ctra Majadahonda Pozuelo km 2, 28220 Majadahonda, Spain
    Trends Parasitol 18:399-405. 2002
    ..Such studies are essential to determine the basis of the canine protective immune response and to establish a laboratory model, a significant aspect for the development of vaccines against canine leishmaniasis...
  19. pmc Protein malnutrition impairs the immune response and influences the severity of infection in a hamster model of chronic visceral leishmaniasis
    Eugenia Carrillo
    WHO Collaborating Centre for Leishmaniasis, Centro Nacional de Microbiologia, Instituto de Salud Carlos III, Madrid, Spain
    PLoS ONE 9:e89412. 2014
    ..The present results show that protein malnutrition promotes visceral leishmaniasis and provide clues regarding the mechanisms underlying the impairment of the immune system. ..
  20. ncbi Evaluation of a specific immunochemotherapy for the treatment of canine visceral leishmaniasis
    Jose Luis Guarga
    Departamento de Patologia Animal, Parasitologia y Enfermedades Parasitarias, Facultad de Veterinaria, C Miguel Servet 177, 50013 Zaragoza, Spain
    Vet Immunol Immunopathol 88:13-20. 2002
    ..Cellular lymphoproliferation studies indicated a lack of a specific response to soluble leishmanial antigen (SLA), but the non-specific lymphoproliferative capacity assayed with phytohemagglutinin (PHA) was maintained...
  21. pmc The relationship between leishmaniasis and AIDS: the second 10 years
    Jorge Alvar
    Control of Neglected Tropical Diseases, World Health Organization, 20 Avenue Appia, CH 1211 Geneva 27, Switzerland
    Clin Microbiol Rev 21:334-59, table of contents. 2008
    ..Based on the previous experience of 20 years of coinfection in Europe, this review focuses on the management of Leishmania-HIV-coinfected patients in low-income countries where leishmaniasis is endemic...
  22. ncbi Synthesis, interaction with double-helical DNA and biological activity of the water soluble complex cis-dichloro-1,2-propylenediamine-N,N,N',N'-tetraacetato ruthenium (III) (RAP)
    Rosario A Vilaplana
    Departamento de Quimica Inorganica, Laboratorio de Química Bioinorgánica, Facultad de Quimica, Universidad de Sevilla, 41071 Sevilla, Spain
    J Inorg Biochem 100:1834-41. 2006
    ..The stability of [RuCl(2)(PDTA-H(2))]-DNA binding is suggested by the high degree of damage that persisted after removal of compound 1 from the culture medium...
  23. ncbi A novel methodology to develop a foot and mouth disease virus (FMDV) peptide-based vaccine in transgenic plants
    María J Dus Santos
    Instituto de Virologia, C I C V, INTA Castelar, CC77, Morón 1708, Pcia De, Buenos Aires, Argentina
    Vaccine 20:1141-7. 2002
    ....