Beatriz Martinez

Summary

Country: Spain

Publications

  1. ncbi request reprint Antimicrobial susceptibility of nisin resistant Listeria monocytogenes of dairy origin
    Beatriz Martinez
    Instituto de Productos Lacteos de Asturias, IPLA CSIC, Carretera de Infiesto s n, 33300 Villaviciosa, Asturias, Spain
    FEMS Microbiol Lett 252:67-72. 2005
  2. ncbi request reprint Consequences of the development of nisin-resistant Listeria monocytogenes in fermented dairy products
    Beatriz Martinez
    Instituto de Productos Lacteos de Asturias, Consejo Superior de Investigaciones Cientificas, 33300 Villaviciosa, Asturias, Spain
    J Food Prot 68:2383-8. 2005
  3. ncbi request reprint Cell envelope stress induced by the bacteriocin Lcn972 is sensed by the Lactococcal two-component system CesSR
    Beatriz Martinez
    Instituto de Productos Lacteos de Asturias, IPLA CSIC Apdo 85 33300 Villaviciosa Asturias, Spain
    Mol Microbiol 64:473-86. 2007
  4. pmc Specific interaction of the unmodified bacteriocin Lactococcin 972 with the cell wall precursor lipid II
    Beatriz Martinez
    Instituto de Productos Lacteos de Asturias, IPLA CSIC, Carretera de Infiesto s n Apdo 85, 33300 Villaviciosa, Spain
    Appl Environ Microbiol 74:4666-70. 2008
  5. pmc Enhanced staphylolytic activity of the Staphylococcus aureus bacteriophage vB_SauS-phiIPLA88 HydH5 virion-associated peptidoglycan hydrolase: fusions, deletions, and synergy with LysH5
    Lorena Rodríguez-Rubio
    Instituto de Productos Lacteos de Asturias IPLA CSIC, Asturias, Spain
    Appl Environ Microbiol 78:2241-8. 2012
  6. ncbi request reprint Rational selection of Leuconostoc strains for mixed starters based on the physiological biodiversity found in raw milk fermentations
    Jorge Ignacio Sánchez
    Instituto de Productos Lacteos de Asturias IPLA CSIC, Ctra Infiesto s n, 33300 Villaviciosa, Asturias, Spain
    Int J Food Microbiol 105:377-87. 2005
  7. doi request reprint Synergy between the phage endolysin LysH5 and nisin to kill Staphylococcus aureus in pasteurized milk
    Pilar Garcia
    Instituto de Productos Lacteos de Asturias, Spain
    Int J Food Microbiol 141:151-5. 2010
  8. pmc Lytic activity of LysH5 endolysin secreted by Lactococcus lactis using the secretion signal sequence of bacteriocin Lcn972
    Lorena Rodríguez-Rubio
    Instituto de Productos Lacteos de Asturias IPLA CSIC, Villaviciosa, Asturias, Spain
    Appl Environ Microbiol 78:3469-72. 2012
  9. pmc Use of green fluorescent protein to monitor cell envelope stress in Lactococcus lactis
    Ana Belén Campelo
    Department of Technology and Biotechnology of Dairy Products, Instituto de Productos Lacteos de Asturias, IPLA CSIC, Apdo 85, 33300 Villaviciosa, Asturias, Spain
    Appl Environ Microbiol 76:978-81. 2010
  10. ncbi request reprint Inhibition of a methicillin-resistant Staphylococcus aureus strain in Afuega'l Pitu cheese by the nisin Z-producing strain Lactococcus lactis subsp. lactis IPLA 729
    Natalia Rilla
    Instituto de Productos Lacteos de Asturias IPLA CSIC, 33300 Villaviciosa, Asturias, Spain
    J Food Prot 67:928-33. 2004

Collaborators

Detail Information

Publications43

  1. ncbi request reprint Antimicrobial susceptibility of nisin resistant Listeria monocytogenes of dairy origin
    Beatriz Martinez
    Instituto de Productos Lacteos de Asturias, IPLA CSIC, Carretera de Infiesto s n, 33300 Villaviciosa, Asturias, Spain
    FEMS Microbiol Lett 252:67-72. 2005
    ..As judged by these results, no clear correlation could be established between resistance to nisin and to worldwide-used antibiotics...
  2. ncbi request reprint Consequences of the development of nisin-resistant Listeria monocytogenes in fermented dairy products
    Beatriz Martinez
    Instituto de Productos Lacteos de Asturias, Consejo Superior de Investigaciones Cientificas, 33300 Villaviciosa, Asturias, Spain
    J Food Prot 68:2383-8. 2005
    ..This resistance should be considered when making a risk assessment of the long-term use of nisin to control L. monocytogenes...
  3. ncbi request reprint Cell envelope stress induced by the bacteriocin Lcn972 is sensed by the Lactococcal two-component system CesSR
    Beatriz Martinez
    Instituto de Productos Lacteos de Asturias, IPLA CSIC Apdo 85 33300 Villaviciosa Asturias, Spain
    Mol Microbiol 64:473-86. 2007
    ..We propose here that CesSR of L. lactis controls the immediate response to cell envelope stress in this organism...
  4. pmc Specific interaction of the unmodified bacteriocin Lactococcin 972 with the cell wall precursor lipid II
    Beatriz Martinez
    Instituto de Productos Lacteos de Asturias, IPLA CSIC, Carretera de Infiesto s n Apdo 85, 33300 Villaviciosa, Spain
    Appl Environ Microbiol 74:4666-70. 2008
    ..To our knowledge, this is the first unmodified bacteriocin that binds to the cell wall precursor lipid II...
  5. pmc Enhanced staphylolytic activity of the Staphylococcus aureus bacteriophage vB_SauS-phiIPLA88 HydH5 virion-associated peptidoglycan hydrolase: fusions, deletions, and synergy with LysH5
    Lorena Rodríguez-Rubio
    Instituto de Productos Lacteos de Asturias IPLA CSIC, Asturias, Spain
    Appl Environ Microbiol 78:2241-8. 2012
    ....
  6. ncbi request reprint Rational selection of Leuconostoc strains for mixed starters based on the physiological biodiversity found in raw milk fermentations
    Jorge Ignacio Sánchez
    Instituto de Productos Lacteos de Asturias IPLA CSIC, Ctra Infiesto s n, 33300 Villaviciosa, Asturias, Spain
    Int J Food Microbiol 105:377-87. 2005
    ..This study evidences the fact that natural environments can be considered as a proper source of new strains, which may help the dairy industry to widen their fermented products range...
  7. doi request reprint Synergy between the phage endolysin LysH5 and nisin to kill Staphylococcus aureus in pasteurized milk
    Pilar Garcia
    Instituto de Productos Lacteos de Asturias, Spain
    Int J Food Microbiol 141:151-5. 2010
    ..As far as we know, this is the first study that exploits the possibilities of hurdle technology combining a phage-encoded endolysin and the bacteriocin nisin for efficient S. aureus inhibition in milk...
  8. pmc Lytic activity of LysH5 endolysin secreted by Lactococcus lactis using the secretion signal sequence of bacteriocin Lcn972
    Lorena Rodríguez-Rubio
    Instituto de Productos Lacteos de Asturias IPLA CSIC, Villaviciosa, Asturias, Spain
    Appl Environ Microbiol 78:3469-72. 2012
    ..Up to 80 U/mg of extracellular active endolysin was detected in culture supernatants, but most of the protein (up to 323 U/mg) remained in the cell extracts...
  9. pmc Use of green fluorescent protein to monitor cell envelope stress in Lactococcus lactis
    Ana Belén Campelo
    Department of Technology and Biotechnology of Dairy Products, Instituto de Productos Lacteos de Asturias, IPLA CSIC, Apdo 85, 33300 Villaviciosa, Asturias, Spain
    Appl Environ Microbiol 76:978-81. 2010
    ..A dot blot assay allowed fast detection of green fluorescent protein (GFP) fluorescence even at low production levels. Unexpectedly, this promoter was also induced by mitomycin C via CesR...
  10. ncbi request reprint Inhibition of a methicillin-resistant Staphylococcus aureus strain in Afuega'l Pitu cheese by the nisin Z-producing strain Lactococcus lactis subsp. lactis IPLA 729
    Natalia Rilla
    Instituto de Productos Lacteos de Asturias IPLA CSIC, 33300 Villaviciosa, Asturias, Spain
    J Food Prot 67:928-33. 2004
    ..8 x 10(4) and 7.2 x 10(6) CFU/ml). The staphylococcal strain was also undetected in test cheeses in which the nisin Z producer was present whereas 2 log units were detected in control cheeses at the end of ripening...
  11. pmc The putative lactococcal extracytoplasmic function anti-sigma factor llmg2447 determines resistance to the cell wall-active bacteriocin lcn972
    Clara Roces
    DairySafe Group, Department of Technology and Biotechnology of Dairy Products, IPLA CSIC, Villaviciosa, Asturias, Spain
    Antimicrob Agents Chemother 56:5520-7. 2012
    ..This new role in neutralizing cell wall-active compounds (e.g., Lcn972) could have evolved from a putative primary function of Llmg2447 in sensing cell envelope stress...
  12. pmc Isolation of Lactococcus lactis mutants simultaneously resistant to the cell wall-active bacteriocin Lcn972, lysozyme, nisin, and bacteriophage c2
    Clara Roces
    Department of Technology and Biotechnology of Dairy Products, Instituto de Productos Lacteos de Asturias IPLA CSIC, Villaviciosa, Asturias, Spain
    Appl Environ Microbiol 78:4157-63. 2012
    ..However, a clear correlation between these genes and resistance to Lcn972 could not be clearly established, pointing to the presence of as-yet-unidentified mutations that account for Lcn972 resistance...
  13. pmc The peptidoglycan hydrolase of Staphylococcus aureus bacteriophage 11 plays a structural role in the viral particle
    Lorena Rodríguez-Rubio
    DairySafe Group, Department of Technology and Biotechnology of Dairy Products, Instituto de Productos Lacteos de Asturias IPLA CSIC, Villaviciosa, Asturias, Spain
    Appl Environ Microbiol 79:6187-90. 2013
    ..11Δ49 phages showed a reduced burst size and delayed host lysis. Complementation of gp49 with HydH5 from bacteriophage vB_SauS-phiIPLA88 restored the wild-type phenotype. ..
  14. pmc The phage lytic proteins from the Staphylococcus aureus bacteriophage vB_SauS-phiIPLA88 display multiple active catalytic domains and do not trigger staphylococcal resistance
    Lorena Rodríguez-Rubio
    DairySafe Group, Department of Technology and Biotechnology of Dairy Products, Instituto de Productos Lácteos de Asturias Consejo Superior de Investigaciones Científicas, Villaviciosa, Asturias, Spain
    PLoS ONE 8:e64671. 2013
    ..However, a quick increase in lysostaphin resistance (up to 1000-fold in liquid culture) was observed. The lack of resistant development supports the use of phage lytic proteins as future therapeutics to treat staphylococcal infections...
  15. pmc The tape measure protein of the Staphylococcus aureus bacteriophage vB_SauS-phiIPLA35 has an active muramidase domain
    Lorena Rodríguez-Rubio
    Instituto de Productos Lacteos de Asturias IPLA CSIC, Department of Technology and Biotechnology of Dairy Products, Asturias, Spain
    Appl Environ Microbiol 78:6369-71. 2012
    ..This report shows that the lysozyme-like domain (TG1) has muramidase activity and exhibits in vitro lytic activity against live S. aureus cells, an activity that could eventually find use in the treatment of infections...
  16. doi request reprint Lack of the host membrane protease FtsH hinders release of the Lactococcus lactis bacteriophage TP712
    Clara Roces
    DairySafe Group, Department of Technology and Biotechnology of Dairy Products, Instituto de Productos Lacteos de Asturias IPLA CSIC, Villaviciosa, Asturias, Spain
    J Gen Virol 94:2814-8. 2013
    ..These virions were infective, demonstrating that a functional host FtsH is required by TP712 to proceed effectively with lysis of the host. ..
  17. ncbi request reprint Enhanced production of lactococcin 972 in chemostat cultures
    Alma Hernández de Rojas
    Instituto de Productos Lacteos de Asturias, Apdo 85, 33300, Villaviciosa, Asturias, Spain
    Appl Microbiol Biotechnol 66:48-52. 2004
    ..Lcn972 behaved as a true primary metabolite, as it was maximally produced when the cells were actively growing. Bacteriocin yields were improved up to ten-fold in chemostat cultures compared with those achieved in batch...
  18. pmc Potential of the virion-associated peptidoglycan hydrolase HydH5 and its derivative fusion proteins in milk biopreservation
    Lorena Rodríguez-Rubio
    DairySafe Group, Department of Technology and Biotechnology of Dairy Products, Instituto de Productos Lácteos de Asturias IPLA, Consejo Superior de Investigaciones Cientificas CSIC, Villaviciosa, Asturias, Spain
    PLoS ONE 8:e54828. 2013
    ..These results might facilitate the use of the peptidoglycan hydrolase HydH5 and its derivative fusions, particularly CHAPSH3b, as biocontrol agents for controlling undesirable bacteria in dairy products...
  19. pmc Culture conditions determine the balance between two different exopolysaccharides produced by Lactobacillus pentosus LPS26
    Jorge Ignacio Sánchez
    Instituto de Productos Lacteos de Asturias IPLA CSIC, Ctra Infiesto s n, 33300 Villaviciosa, Spain
    Appl Environ Microbiol 72:7495-502. 2006
    ..Finally, it should be noted that this is, to our knowledge, the first report on EPS production by L. pentosus...
  20. pmc Lytic activity of the virion-associated peptidoglycan hydrolase HydH5 of Staphylococcus aureus bacteriophage vB_SauS-phiIPLA88
    Lorena Rodriguez
    Instituto de Productos Lacteos de Asturias IPLA CSIC, Apdo, Asturias, Spain
    BMC Microbiol 11:138. 2011
    ..In this context, bacteriophage lytic enzymes such as endolysins and structural peptidoglycan (PG) hydrolases have received considerable attention as possible antimicrobials against gram-positive bacteria...
  21. pmc The Lcn972 bacteriocin-encoding plasmid pBL1 impairs cellobiose metabolism in Lactococcus lactis
    Ana B Campelo
    DairySafe Group, Department of Technology and Biotechnology of Dairy Products, IPLA CSIC, Carretera de Infiesto s n, Apdo 85, 33300 Villaviciosa, Asturias, Spain
    Appl Environ Microbiol 77:7576-85. 2011
    ..Thus, downregulation of celB could help to build up a response against the antimicrobial activity of Lcn972, enhancing self-immunity of the producer cells...
  22. ncbi request reprint Application of reverse transcriptase PCR-based T-RFLP to perform semi-quantitative analysis of metabolically active bacteria in dairy fermentations
    Jorge I Sánchez
    Instituto de Productos Lacteos de Asturias IPLA CSIC, ctra Infiesto, S N, 33300 Villaviciosa, Asturias, Spain
    J Microbiol Methods 65:268-77. 2006
    ..RT-PCR-based T-RFLP can be an alternative to classical methods in order to study dynamics of metabolically active populations in relatively simple microbial ecosystems, such as defined dairy starter cultures...
  23. pmc Genomic characterization of two Staphylococcus epidermidis bacteriophages with anti-biofilm potential
    Diana Gutiérrez
    DairySafe Group, Department of Technology and Biotechnology of Dairy Products, Instituto de Productos Lacteos de Asturias IPLA CSIC, Paseo Río Linares, 33300 Villaviciosa, Asturias, Spain
    BMC Genomics 13:228. 2012
    ..In this context, the use of phages to destroy biofilms is an interesting alternative...
  24. pmc Functional genomic analysis of two Staphylococcus aureus phages isolated from the dairy environment
    Pilar Garcia
    Instituto de Productos Lacteos de Asturias, Consejo Superior de Investigaciones Cientificas, Apdo 85, 33300 Villaviciosa, Asturias, Spain
    Appl Environ Microbiol 75:7663-73. 2009
    ..Comparative analysis of phiIPLA35 and phiIPLA88 genome structures shows that they resemble those of phi12 and phi11, respectively, both representatives of large genomic groupings within the S. aureus-infecting phages...
  25. doi request reprint Prophage induction in Lactococcus lactis by the bacteriocin Lactococcin 972
    Carmen Madera
    Instituto de Productos Lacteos de Asturias IPLA CSIC, Villaviciosa, Asturias, Spain
    Int J Food Microbiol 129:99-102. 2009
    ..Since Lcn972 is active against L. lactis strains currently used in commercial starters, promising applications for dairy fermentations are discussed...
  26. doi request reprint Lytic activity of the recombinant staphylococcal bacteriophage PhiH5 endolysin active against Staphylococcus aureus in milk
    José María Obeso
    Instituto de Productos Lacteos de Asturias IPLA CSIC, Apdo 85 33300 Villaviciosa, Asturias, Spain
    Int J Food Microbiol 128:212-8. 2008
    ..As far as we know, this is the first report to assess the antimicrobial activity of a phage endolysin which might be useful for novel biocontrol strategies in dairying...
  27. pmc The Behavior of Staphylococcus aureus Dual-Species Biofilms Treated with Bacteriophage phiIPLA-RODI Depends on the Accompanying Microorganism
    Silvia Gonzalez
    Instituto de Productos Lacteos de Asturias IPLA CSIC, Villaviciosa, Asturias, Spain
    Appl Environ Microbiol 83:. 2017
    ..Altogether, the results presented here highlight the need to study the impact of phage therapy on microbial communities that reflect a more realistic setting...
  28. pmc Incidence of Staphylococcus aureus and analysis of associated bacterial communities on food industry surfaces
    Diana Gutiérrez
    Instituto de Productos Lacteos de Asturias IPLA CSIC, Villaviciosa, Asturias, Spain
    Appl Environ Microbiol 78:8547-54. 2012
    ....
  29. doi request reprint Phage inactivation of Staphylococcus aureus in fresh and hard-type cheeses
    Edita Bueno
    Instituto de Productos Lacteos de Asturias IPLA CSIC, Department of Technology and Biotechnology of Dairy Products, 33300 Villaviciosa, Asturias, Spain
    Int J Food Microbiol 158:23-7. 2012
    ..73log CFU/g was present in control cheeses. Starter strains were not affected by the presence of phages in the cheese making processes and cheeses maintained their expected physico-chemical properties...
  30. doi request reprint Phage sensitivity and prophage carriage in Staphylococcus aureus isolated from foods in Spain and New Zealand
    Diana Gutiérrez
    Instituto de Productos Lácteos de Asturias IPLA CSIC Paseo Río Linares s n, 33300 Villaviciosa, Asturias, Spain
    Int J Food Microbiol 230:16-20. 2016
    ..aureus strains, but were infrequently detected in New Zealand strains. Overall, the correlation between phage resistance and lysogeny in S. aureus strains was found to be weak. ..
  31. doi request reprint Contribution of the CesR-regulated genes llmg0169 and llmg2164-2163 to Lactococcus lactis fitness
    Clara Roces
    Department of Technology and Biotechnology of Dairy Products, Instituto de Productos Lacteos de Asturias IPLA CSIC, Asturias, Spain
    Int J Food Microbiol 133:279-85. 2009
    ..lactis under technologically-relevant stresses and their functionality could be a useful marker to select robust dairy starters...
  32. doi request reprint Nisin-bacteriophage crossresistance in Staphylococcus aureus
    Beatriz Martinez
    Instituto de Productos Lácteos de Asturias IPLA CSIC Apdo 85 33300 Villaviciosa, Asturias, Spain
    Int J Food Microbiol 122:253-8. 2008
    ..In contrast, bacteriophage insensitive mutants were not nisin resistant. The results indicate that careful use of nisin and bacteriophages in combination is required for control of S. aureus in dairy products...
  33. pmc Use of logistic regression for prediction of the fate of Staphylococcus aureus in pasteurized milk in the presence of two lytic phages
    José M Obeso
    Instituto de Productos Lacteos de Asturias IPLA CSIC, 33300 Villaviciosa, Asturias, Spain
    Appl Environ Microbiol 76:6038-46. 2010
    ..Besides, the global model provides the minimum phage concentration (about 2 x 10(8) PFU/ml) required to inactivate S. aureus in milk at different temperatures, irrespective of the bacterial contamination level...
  34. doi request reprint Isolation and characterization of bacteriophages infecting Staphylococcus epidermidis
    Diana Gutiérrez
    Instituto de Productos Lacteos de Asturias IPLA CSIC, Apdo 85, 33300, Villaviciosa, Asturias, Spain
    Curr Microbiol 61:601-8. 2010
    ..epidermidis population by 5.67 log units in 8 h of incubation; in the presence of the mixture of phi-IPLA6 and phi-IPLA7, however, a reduction of 2.27 log units was detected...
  35. doi request reprint Typing of bacteriophages by randomly amplified polymorphic DNA (RAPD)-PCR to assess genetic diversity
    Diana Gutiérrez
    DairySafe Group, Instituto de Productos Lacteos de Asturias IPLA CSIC, Villaviciosa, Asturias, Spain
    FEMS Microbiol Lett 322:90-7. 2011
    ..The results support the use of RAPD-PCR for quick typing of phage isolates and preliminary assessment of their genetic diversity bypassing tedious DNA purification protocols and previous knowledge of their sequence...
  36. pmc Bacteriophages as Weapons Against Bacterial Biofilms in the Food Industry
    Diana Gutiérrez
    Instituto de Productos Lacteos de Asturias, Consejo Superior de Investigaciones Científicas Villaviciosa, Spain
    Front Microbiol 7:825. 2016
    ..In this regard, this review examines the environmental factors that determine biofilm development in food-processing equipment. In addition, future perspectives for the use of bacteriophage-derived tools as disinfectants are discussed. ..
  37. pmc 'Artilysation' of endolysin λSa2lys strongly improves its enzymatic and antibacterial activity against streptococci
    Lorena Rodríguez-Rubio
    Instituto de Productos Lacteos de Asturias IPLA CSIC, Paseo Río Linares s n 33300 Villaviciosa, Asturias, Spain
    Sci Rep 6:35382. 2016
    ..In addition, lower doses of Art-240 are required to achieve the same bactericidal effect...
  38. pmc Two Phages, phiIPLA-RODI and phiIPLA-C1C, Lyse Mono- and Dual-Species Staphylococcal Biofilms
    Diana Gutiérrez
    Instituto de Productos Lacteos de Asturias IPLA CSIC, Departamento de Tecnología y Biotecnología de Productos Lácteos Villaviciosa, Asturias, Spain
    Appl Environ Microbiol 81:3336-48. 2015
    ..These results confirm that lytic bacteriophages can be efficient biofilm-disrupting agents, supporting their potential as antimicrobials against staphylococcal infections. ..
  39. pmc Low-level predation by lytic phage phiIPLA-RODI promotes biofilm formation and triggers the stringent response in Staphylococcus aureus
    Lucía Fernández
    Instituto de Productos Lacteos de Asturias IPLA CSIC, Paseo Rio Linares s n 33300, Villaviciosa, Asturias, Spain
    Sci Rep 7:40965. 2017
    ....
  40. pmc Effective removal of staphylococcal biofilms by the endolysin LysH5
    Diana Gutiérrez
    Instituto de Productos Lacteos de Asturias IPLA CSIC, Villaviciosa, Asturias, Spain
    PLoS ONE 9:e107307. 2014
    ..The results demonstrated that besides the notable activity of endolysin LysH5 against staphylococcal biofilms, persister cells were also inhibited, which raises new opportunities as an adjuvant for some antibiotics. ..
  41. doi request reprint Listeriaphages and coagulin C23 act synergistically to kill Listeria monocytogenes in milk under refrigeration conditions
    Lorena Rodríguez-Rubio
    DairySafe Group, Department of Technology and Biotechnology of Dairy Products, Instituto de Productos Lacteos de Asturias IPLA CSIC, 33300 Villaviciosa, Asturias, Spain
    Int J Food Microbiol 205:68-72. 2015
    ....
  42. pmc A bacteriocin gene cluster able to enhance plasmid maintenance in Lactococcus lactis
    Ana B Campelo
    Dairy Safe group, Department Technology and Biotechnology of Dairy Products, Instituto de Productos Lácteos de AsturiasIPLA CSIC, Paseo Río Linares, S N, 33300 Villaviciosa, Asturias, Spain
    Microb Cell Fact 13:77. 2014
    ..lactis in the absence of antibiotics. Lcn972 is a non-lantibiotic bacteriocin encoded by the 11-kbp plasmid pBL1 with a potent antimicrobial activity against Lactococcus...
  43. doi request reprint Cell Wall-active Bacteriocins and Their Applications Beyond Antibiotic Activity
    Clara Roces
    DairySafe Group, Department of Technology and Biotechnology of Dairy Products, Instituto de Productos Lacteos de Asturias IPLA CSIC, Paseo Río Linares s n, 33300, Villaviciosa, Asturias, Spain
    Probiotics Antimicrob Proteins 4:259-72. 2012
    ..Moreover, even though bacteriocins have been a matter of interest as natural food antimicrobials, we propose them as suitable tools to provide new means to improve biotechnologically relevant microorganisms. ..