Anouchka Skoudy

Summary

Affiliation: Hospital del Mar
Country: Spain

Publications

  1. pmc Murine embryonic stem cell-derived pancreatic acinar cells recapitulate features of early pancreatic differentiation
    Meritxell Rovira
    Cancer Research Program, Institut Municipal d Investigacio Medica, Barcelona, Spain
    Gastroenterology 135:1301-1310, 1310.e1-5. 2008
  2. pmc Directed pancreatic acinar differentiation of mouse embryonic stem cells via embryonic signalling molecules and exocrine transcription factors
    Fabien Delaspre
    Cancer Research Program, Institut Hospital del Mar d Investigacions Mèdiques IMIM, Biomedical Research Park, Barcelona, Spain
    PLoS ONE 8:e54243. 2013
  3. pmc Transforming growth factor (TGF)beta, fibroblast growth factor (FGF) and retinoid signalling pathways promote pancreatic exocrine gene expression in mouse embryonic stem cells
    Anouchka Skoudy
    Unitat de Biologia Cel lular i Molecular, Institut Municipal d Investigacio Medica, 08003 Barcelona, Spain
    Biochem J 379:749-56. 2004
  4. ncbi Viral-mediated coexpression of Pdx1 and p48 regulates exocrine pancreatic differentiation in mouse ES cells
    Meritxell Rovira
    Cell and Molecular Biology Unit, Institut Municipal d Investigacio Medica IMIM, Dr Aiguader 88, Barcelona, Spain
    Cloning Stem Cells 9:327-38. 2007
  5. doi The epigenetic regulators Bmi1 and Ring1B are differentially regulated in pancreatitis and pancreatic ductal adenocarcinoma
    Carles Martínez-Romero
    Institut Municipal d Investigacio Medica, Hospital del Mar, Barcelona, Spain
    J Pathol 219:205-13. 2009
  6. doi Pancreatic ductal adenocarcinoma and transcription factors: role of c-Myc
    Anouchka Skoudy
    Cancer Research Programme, IMIM Institut de Recerca Hospital del Mar, Dr Aiguader 88, Barcelona, Spain
    J Gastrointest Cancer 42:76-84. 2011
  7. ncbi PTF1alpha/p48 transcription factor couples proliferation and differentiation in the exocrine pancreas [corrected]
    Annie Rodolosse
    Unitat de Biologia Cellular i Molecular, Institut Municipal d Investigacio Medica, Barcelona, Spain
    Gastroenterology 127:937-49. 2004
  8. doi Pancreatic ductal adenocarcinoma: cellular origin, signaling pathways and stroma contribution
    Inmaculada Hernández-Muñoz
    Programa de Recerca en Càncer, Institut Municipal d Investigació Mèdica IMIM Hospital del Mar, Barcelona, Spain
    Pancreatology 8:462-9. 2008
  9. pmc Diabetes and exocrine pancreatic insufficiency in E2F1/E2F2 double-mutant mice
    Ainhoa Iglesias
    Department of Genetics, Physical Anthropology and Animal Physiology, Faculty of Sciences, University of the Basque Country, Bilbao, Spain
    J Clin Invest 113:1398-407. 2004

Collaborators

  • Francisco X Real
  • Pierre Savatier
  • Stephen F Konieczny
  • Carmen Guerra
  • Ilse Rooman
  • Philippe Ravassard
  • B Soria
  • Meritxell Rovira
  • Fabien Delaspre
  • Inmaculada Hernández-Muñoz
  • Mohammad Massumi
  • Carles Martínez-Romero
  • Ainhoa Iglesias
  • Annie Rodolosse
  • Marta Salido
  • Almudena Bosch
  • Xavier Molero
  • Mariano Barbacid
  • Mar Iglesias
  • Tania Lobato
  • Ana Gonzalez
  • Pilar Navarro
  • Bruno Payre
  • Josep Lloreta
  • Selma A Serra
  • Miguel Angel Valverde
  • Marlene Dufresne
  • Mélanie Marchand
  • Judit Jane-Valbuena
  • Seth J Field
  • Usua Laresgoiti
  • Elisabet Chalaux
  • Matilde Murga
  • Bernardino Moreno
  • José Lloreta
  • Irantzu Bernales
  • Asier Fullaondo
  • Ana M Zubiaga
  • Hélène Hagège
  • Teresa Adell

Detail Information

Publications9

  1. pmc Murine embryonic stem cell-derived pancreatic acinar cells recapitulate features of early pancreatic differentiation
    Meritxell Rovira
    Cancer Research Program, Institut Municipal d Investigacio Medica, Barcelona, Spain
    Gastroenterology 135:1301-1310, 1310.e1-5. 2008
    ..However, there are limited models to study normal acinar cell differentiation in vitro. The aim of this work was to generate and characterize purified populations of pancreatic acinar cells from embryonic stem (ES) cells...
  2. pmc Directed pancreatic acinar differentiation of mouse embryonic stem cells via embryonic signalling molecules and exocrine transcription factors
    Fabien Delaspre
    Cancer Research Program, Institut Hospital del Mar d Investigacions Mèdiques IMIM, Biomedical Research Park, Barcelona, Spain
    PLoS ONE 8:e54243. 2013
    ..This study provides a novel method to produce functional pancreatic exocrine cells from ESC...
  3. pmc Transforming growth factor (TGF)beta, fibroblast growth factor (FGF) and retinoid signalling pathways promote pancreatic exocrine gene expression in mouse embryonic stem cells
    Anouchka Skoudy
    Unitat de Biologia Cel lular i Molecular, Institut Municipal d Investigacio Medica, 08003 Barcelona, Spain
    Biochem J 379:749-56. 2004
    ....
  4. ncbi Viral-mediated coexpression of Pdx1 and p48 regulates exocrine pancreatic differentiation in mouse ES cells
    Meritxell Rovira
    Cell and Molecular Biology Unit, Institut Municipal d Investigacio Medica IMIM, Dr Aiguader 88, Barcelona, Spain
    Cloning Stem Cells 9:327-38. 2007
    ..Therefore, combined expression of key genes involved in pancreatic development may be a promising approach to generate mature pancreatic exocrine cells...
  5. doi The epigenetic regulators Bmi1 and Ring1B are differentially regulated in pancreatitis and pancreatic ductal adenocarcinoma
    Carles Martínez-Romero
    Institut Municipal d Investigacio Medica, Hospital del Mar, Barcelona, Spain
    J Pathol 219:205-13. 2009
    ..Our results suggest that Bmi1 and Ring1B are modulated in pancreatic diseases and could contribute differently to tumour development...
  6. doi Pancreatic ductal adenocarcinoma and transcription factors: role of c-Myc
    Anouchka Skoudy
    Cancer Research Programme, IMIM Institut de Recerca Hospital del Mar, Dr Aiguader 88, Barcelona, Spain
    J Gastrointest Cancer 42:76-84. 2011
    ..Furthermore, most oncogenic signaling pathways converge on sets of transcription factors that ultimately control gene expression patterns resulting in cancer development, progression, and metastasis...
  7. ncbi PTF1alpha/p48 transcription factor couples proliferation and differentiation in the exocrine pancreas [corrected]
    Annie Rodolosse
    Unitat de Biologia Cellular i Molecular, Institut Municipal d Investigacio Medica, Barcelona, Spain
    Gastroenterology 127:937-49. 2004
    ..The aim was to analyze the ability of p48 to modulate cell proliferation, its relationship with cell differentiation, and the mechanisms involved therein...
  8. doi Pancreatic ductal adenocarcinoma: cellular origin, signaling pathways and stroma contribution
    Inmaculada Hernández-Muñoz
    Programa de Recerca en Càncer, Institut Municipal d Investigació Mèdica IMIM Hospital del Mar, Barcelona, Spain
    Pancreatology 8:462-9. 2008
    ..An improved understanding of these key aspects for PDAC ontogeny will open new avenues for tumor prevention, early detection, and improved therapy...
  9. pmc Diabetes and exocrine pancreatic insufficiency in E2F1/E2F2 double-mutant mice
    Ainhoa Iglesias
    Department of Genetics, Physical Anthropology and Animal Physiology, Faculty of Sciences, University of the Basque Country, Bilbao, Spain
    J Clin Invest 113:1398-407. 2004
    ..These results suggest that E2F1/E2F2 activity negatively controls growth of mature pancreatic cells and is necessary for the maintenance of differentiated pancreatic phenotypes in the adult...