Josep Lloreta

Summary

Affiliation: Hospital del Mar
Country: Spain

Publications

  1. pmc Centrosome clustering and cyclin D1 gene amplification in double minutes are common events in chromosomal unstable bladder tumors
    Javier del Rey
    Departament de Biologia Cellular Fisiologia i Immunologia, Institut de Biotecnologia i de Biomedicina, Universitat Autonoma de Barcelona, 08193 Bellaterra, Spain
    BMC Cancer 10:280. 2010
  2. ncbi request reprint Extrathoracic mesothelial proliferations and their mimics
    Josep Lloreta-Trull
    Department of Pathology, Hospital del Mar IMAS IMIM, Universitat Pompeu Fabra, Barcelona, Spain
    Ultrastruct Pathol 30:37-51. 2006
  3. ncbi request reprint Ultrastructural features of highly active antiretroviral therapy-associated partial lipodystrophy
    Josep Lloreta
    Department of Pathology, Hospital del Mar IMAS IMIM, Universitat Pompeu Fabra, Passeig Maritim 25 29, 08003 Barcelona, Spain
    Virchows Arch 441:599-604. 2002
  4. ncbi request reprint The current role of electron microscopy in the diagnosis of epithelial and epithelioid tumors
    Josep Lloreta-Trull
    Department of Pathology, Hospital del Mar IMAS IMIM, Universitat Pompeu Fabra, and Autonomous University of Barcelona, Barcelona, Spain
    Semin Diagn Pathol 20:46-59. 2003
  5. doi request reprint Molecular alterations of EGFR and PTEN in prostate cancer: association with high-grade and advanced-stage carcinomas
    Silvia de Muga
    Department of Health and Experimental Sciences, Universitat Pompeu Fabra, Barcelona, Spain
    Mod Pathol 23:703-12. 2010
  6. doi request reprint KLF6 and TP53 mutations are a rare event in prostate cancer: distinguishing between Taq polymerase artifacts and true mutations
    Laia Agell
    Department of Pathology, Hospital del Mar, Barcelona, Spain
    Mod Pathol 21:1470-8. 2008
  7. doi request reprint Mutations in FGFR3 and PIK3CA, singly or combined with RAS and AKT1, are associated with AKT but not with MAPK pathway activation in urothelial bladder cancer
    Nuria Juanpere
    Department of Pathology, Hospital del Mar Parc de Salut Mar, 08003 Barcelona, Spain
    Hum Pathol 43:1573-82. 2012
  8. doi request reprint PI3K signaling pathway is activated by PIK3CA mRNA overexpression and copy gain in prostate tumors, but PIK3CA, BRAF, KRAS and AKT1 mutations are infrequent events
    Laia Agell
    Department of Pathology, Hospital del Mar Parc de Salut Mar, Barcelona, Spain
    Mod Pathol 24:443-52. 2011
  9. doi request reprint Concurrent TMPRSS2-ERG and SLC45A3-ERG rearrangements plus PTEN loss are not found in low grade prostate cancer and define an aggressive tumor subset
    Silvia Hernandez
    Department of Health and Experimental Sciences, Universitat Pompeu Fabra, Barcelona, Spain
    Prostate 76:854-65. 2016
  10. doi request reprint CXCR4 mRNA overexpression in high grade prostate tumors: lack of association with TMPRSS2-ERG rearrangement
    Silvia de Muga
    Department of Pathology, Hospital del Mar Parc de Salut Mar IMIM, Barcelona, Spain
    Cancer Biomark 12:21-30. 2012

Collaborators

Detail Information

Publications38

  1. pmc Centrosome clustering and cyclin D1 gene amplification in double minutes are common events in chromosomal unstable bladder tumors
    Javier del Rey
    Departament de Biologia Cellular Fisiologia i Immunologia, Institut de Biotecnologia i de Biomedicina, Universitat Autonoma de Barcelona, 08193 Bellaterra, Spain
    BMC Cancer 10:280. 2010
    ..Aneuploidy, centrosome abnormalities and gene amplification are hallmarks of chromosome instability (CIN) in cancer. Yet there are no studies of the in vivo behavior of these phenomena within the same bladder tumor...
  2. ncbi request reprint Extrathoracic mesothelial proliferations and their mimics
    Josep Lloreta-Trull
    Department of Pathology, Hospital del Mar IMAS IMIM, Universitat Pompeu Fabra, Barcelona, Spain
    Ultrastruct Pathol 30:37-51. 2006
    ....
  3. ncbi request reprint Ultrastructural features of highly active antiretroviral therapy-associated partial lipodystrophy
    Josep Lloreta
    Department of Pathology, Hospital del Mar IMAS IMIM, Universitat Pompeu Fabra, Passeig Maritim 25 29, 08003 Barcelona, Spain
    Virchows Arch 441:599-604. 2002
    ....
  4. ncbi request reprint The current role of electron microscopy in the diagnosis of epithelial and epithelioid tumors
    Josep Lloreta-Trull
    Department of Pathology, Hospital del Mar IMAS IMIM, Universitat Pompeu Fabra, and Autonomous University of Barcelona, Barcelona, Spain
    Semin Diagn Pathol 20:46-59. 2003
    ....
  5. doi request reprint Molecular alterations of EGFR and PTEN in prostate cancer: association with high-grade and advanced-stage carcinomas
    Silvia de Muga
    Department of Health and Experimental Sciences, Universitat Pompeu Fabra, Barcelona, Spain
    Mod Pathol 23:703-12. 2010
    ..Alterations in the EGFR-PTEN signaling pathway are present in a third of prostate adenocarcinomas, particularly affecting the more advanced cases...
  6. doi request reprint KLF6 and TP53 mutations are a rare event in prostate cancer: distinguishing between Taq polymerase artifacts and true mutations
    Laia Agell
    Department of Pathology, Hospital del Mar, Barcelona, Spain
    Mod Pathol 21:1470-8. 2008
    ..When using FFPE tissues, it is mandatory to perform at least two independent rounds of PCR and sequencing to confirm mutations and exclude Taq polymerase-induced artifacts...
  7. doi request reprint Mutations in FGFR3 and PIK3CA, singly or combined with RAS and AKT1, are associated with AKT but not with MAPK pathway activation in urothelial bladder cancer
    Nuria Juanpere
    Department of Pathology, Hospital del Mar Parc de Salut Mar, 08003 Barcelona, Spain
    Hum Pathol 43:1573-82. 2012
    ..Other genes different from FGFR3 may be related with the pERK activation in bladder tumors...
  8. doi request reprint PI3K signaling pathway is activated by PIK3CA mRNA overexpression and copy gain in prostate tumors, but PIK3CA, BRAF, KRAS and AKT1 mutations are infrequent events
    Laia Agell
    Department of Pathology, Hospital del Mar Parc de Salut Mar, Barcelona, Spain
    Mod Pathol 24:443-52. 2011
    ..PIK3CA, BRAF, KRAS and AKT1 mutations are very infrequent events in prostate tumors. However, PI3K signaling pathway is activated by PIK3CA FISH gain and/or mRNA overexpression, leading to an increased pAKT protein expression...
  9. doi request reprint Concurrent TMPRSS2-ERG and SLC45A3-ERG rearrangements plus PTEN loss are not found in low grade prostate cancer and define an aggressive tumor subset
    Silvia Hernandez
    Department of Health and Experimental Sciences, Universitat Pompeu Fabra, Barcelona, Spain
    Prostate 76:854-65. 2016
    ..SLC45A3 is the second most common ERG partner in prostate cancer (PrCa). Coexisting TMPRSS2 and SLC45A3 rearrangements are found in a subset of cases, but the meaning is still unknown...
  10. doi request reprint CXCR4 mRNA overexpression in high grade prostate tumors: lack of association with TMPRSS2-ERG rearrangement
    Silvia de Muga
    Department of Pathology, Hospital del Mar Parc de Salut Mar IMIM, Barcelona, Spain
    Cancer Biomark 12:21-30. 2012
    ..In conclusion, our results reveal for the first time that CXCR4 overexpression is associated with high Gleason score prostate tumors, but that it is independent of the TMPRSS2-ERG rearrangement...
  11. ncbi request reprint PIK3CA mutations are an early genetic alteration associated with FGFR3 mutations in superficial papillary bladder tumors
    Elena Lopez-Knowles
    Institut Municipal d Investigacio Medica, Universitat Pompeu Fabra, Carrer del Dr Aiguader 80, 08003 Barcelona, Spain
    Cancer Res 66:7401-4. 2006
    ..PIK3CA may constitute a novel diagnostic and prognostic tool, as well as a therapeutic target, in bladder cancer...
  12. ncbi request reprint The p53 pathway and outcome among patients with T1G3 bladder tumors
    Elena Lopez-Knowles
    Institut Municipal d Investigacio Medica, Universitat Pompeu Fabra, and Hospital del Mar, Barcelona, Spain
    Clin Cancer Res 12:6029-36. 2006
    ..The aim was to analyze Tp53 and HDM2 in T1G3 bladder tumors and to determine the prognostic value of their alterations...
  13. doi request reprint A 12-gene expression signature is associated with aggressive histological in prostate cancer: SEC14L1 and TCEB1 genes are potential markers of progression
    Laia Agell
    Department of Pathology, Hospital del Mar Mar Health Park, Barcelona, Spain
    Am J Pathol 181:1585-94. 2012
    ..This set of genes may contribute to a better understanding of the molecular basis of prostate cancer. TCEB1 and SELC14L1 are good candidate markers for predicting prognosis and progression of prostate cancer...
  14. doi request reprint A multicolor fluorescence in situ hybridization assay: A monitoring tool in the surveillance of patients with a history of non-muscle-invasive urothelial cell carcinoma: A prospective study
    Ana B Galván
    Molecular Cytogenetics Laboratory, Department of Pathology, Hospital del Mar Research Institute, Barcelona, Spain
    Cancer Cytopathol 119:395-403. 2011
    ..The aim of the current study was to compare a multicolor fluorescence in situ hybridization (FISH) assay (UroVysion) with routine follow-up (cystoscopy and cytology) in the monitoring of patients with a previous history of NMIUCC...
  15. doi request reprint Association of ERG and TMPRSS2-ERG with grade, stage, and prognosis of prostate cancer is dependent on their expression levels
    Alba Font-Tello
    Department of Pathology, Hospital del Mar Parc de Salut Mar IMIM, Barcelona, Spain
    Prostate 75:1216-26. 2015
    ..The quantitative differences in TMPRSS2-ERG fusion expression have received very limited attention in the literature...
  16. doi request reprint Cardiac myxoma with glandular differentiation: an immunohistochemical and ultrastructural study
    Josep Lloreta
    Hospital del Mar, Universitat Pompeu Fabra, Barcelona, Spain
    Ultrastruct Pathol 37:77-82. 2013
    ..Further studies are required to unravel the relationship between stellate cells and the diverse heterologous components reported in these tumors...
  17. doi request reprint Value of p16(INK4a) in the diagnosis of low-grade urothelial carcinoma of the urinary bladder in urinary cytology
    Francesc Alameda
    Department of Pathology, Hospital of the Sea, Barcelona, Spain
    Cancer Cytopathol 120:276-82. 2012
    ..Immunocytochemical expression of p16(INK4a) has been examined in biopsy samples from urothelial carcinomas, but few studies have addressed this protein in urine cytology...
  18. doi request reprint FGFR3 mutations in prostate cancer: association with low-grade tumors
    Silvia Hernandez
    Department of Health and Experimental Sciences, Universitat Pompeu Fabra, Barcelona, Spain
    Mod Pathol 22:848-56. 2009
    ..This gene does not seem to be central to the pathogenesis of prostate cancer, but it is significantly associated with a subgroup of low-grade prostate tumors, and with the finding of other tumors, mainly arising in bladder and skin...
  19. doi request reprint FOXO1 downregulation is associated with worse outcome in bladder cancer and adds significant prognostic information to p53 overexpression
    Josep Lloreta
    Department of Pathology, Hospital del Mar, Barcelona, Spain Department of Health and Experimental Sciences, Universitat Pompeu Fabra, Barcelona, Spain
    Hum Pathol . 2017
    ..It may be particularly informative on the risk of progression in the more indolent and on the risk of recurrence in the more aggressive tumors...
  20. ncbi request reprint Acquired mucosal indeterminate cell histiocytoma
    Marta Ferran
    Department of Dermatology, Hospital del Mar, IMAS, Universitat Autonoma de Barcelona, Barcelona, Spain
    Pediatr Dermatol 24:253-6. 2007
    ..The morphologic features and diagnostic criteria of cutaneous indeterminate cell histiocytic proliferations are reviewed. The possible relationship between indeterminate cell and Langerhans cell histiocytoses is discussed...
  21. ncbi request reprint Primitive round cell liposarcoma of the omentum: diagnostic value of ultrastructural study
    Francesc Alameda
    Department of Pathology, Hospital del Mar, Barcelona, Spain
    Ultrastruct Pathol 27:433-7. 2003
    ..This case illustrates the importance of ultrastructural study and the limitations of immunohistochemistry in the diagnosis of such tumors, particularly when they grow in unusual locations...
  22. ncbi request reprint Large cell lymphoma-like reaction in a cervical polyp
    Francesc Alameda
    Department of Pathology, Hospital Universitari del Mar, Passeig Maritim 25 29, 08003 Barcelona, Catalunya, Spain
    Gynecol Oncol 99:481-5. 2005
    ..Inflammatory lesions of the uterine cervix are very common, and although lymphomas in this location are rare, the differential diagnosis between both diseases must be considered in some cases and may be difficult to achieve...
  23. doi request reprint Verruciform xanthoma developing in recessive dystrophic epidermolysis bullosa: A sheep in wolf's clothing
    Laia Curto-Barredo
    Departments of Dermatology Pathology, Hospital del Mar, Parc de Salut Mar, Barcelona, Spain Department of Dermatology, Instituto Valenciano de Oncologia, Valencia, Spain
    Am J Dermatopathol 36:506-9. 2014
    ..In vivo noninvasive image technologies such as reflectance confocal microscopy may be helpful diagnostic tools in this clinical setting...
  24. doi request reprint Bladder cancer and seroreactivity to BK, JC and Merkel cell polyomaviruses: the Spanish bladder cancer study
    Claudia Robles
    Unit of Infections and Cancer, Cancer Epidemiology Research Programme, Catalan Institute of Oncology, IDIBELL, 08908 L Hospitalet de Llobregat, Barcelona, Spain
    Int J Cancer 133:597-603. 2013
    ..Furthermore, no association was observed between seroresponse to JCV and bladder cancer. Therefore, we conclude that BKV and MCV polyomavirus infection could be related to an increased bladder cancer risk...
  25. ncbi request reprint [Biochemical-histo-morphometric findings of the residual prostate (II): long-term PSA behavior after retropubic adenomectomy for BPH. Relationship with prostate volume, histology and its implications in the diagnosis of subsequent adenocarcinoma]
    Juan José Ballesteros Sampol
    Servicios de Urología y de Patología de los Hospitales del IMAS Barcelona, Espana
    Arch Esp Urol 62:713-8. 2009
    ....
  26. ncbi request reprint [Report of two cases of bladder and prostate oat cell tumors]
    Juan José Ballesteros Sampol
    Servicios de Urología y Patología del Hospital de la Esperanza, Barcelona, Espana
    Arch Esp Urol 58:170-5. 2005
    ..To report two cases of bladder and prostate oat cell tumors with bad outcome, in accordance to the bibliographic review...
  27. ncbi request reprint [Histomorphometric findings in the residual prostate and prostatic hollow after retropubic surgery for BPH: (I) baseline data obtained from the last 70 consecutive cases]
    Juan José Ballesteros Sampol
    Servicio de Urologia de los Hospitales del I M A S Barcelona, Espana
    Arch Esp Urol 60:1.069-76. 2007
    ..All this is the first step for the long-term study of its evolution and possible implications in the genesis of new obstructive or neoplastic pathology...
  28. pmc Effect of insulin on ACE2 activity and kidney function in the non-obese diabetic mouse
    Marta Riera
    Department of Nephrology, Hospital del Mar IMIM, Barcelona, Spain
    PLoS ONE 9:e84683. 2014
    ..ACE2 activity is increased starting at an early stage in both serum and urine. Moreover, these alterations can be completely prevented by the chronic administration of insulin. ..
  29. ncbi request reprint Large atypical melanocytic nevi in recessive dystrophic epidermolysis bullosa: clinicopathological, ultrastructural, and dermoscopic study
    Fernando Gallardo
    Department of Dermatology, Hospital del Mar, IMAS, Barcelona, Spain
    Pediatr Dermatol 22:338-43. 2005
    ..The clinical, histopathologic and ultrastructural features of these nevi are reviewed. The usefulness of dermoscopic examination in the routine diagnosis and follow-up of these lesions are stressed...
  30. ncbi request reprint Cranial fasciitis in an 8-year-old boy: clinical and histopathologic features
    Mireia Yébenes
    Department of Dermatology, Hospital del Mar, IMAS, Barcelona, Spain
    Pediatr Dermatol 24:E26-30. 2007
    ..An increased awareness of the clinical and histopathologic characteristics of this entity seems important to establish the diagnosis, to adopt an adequate, conservative treatment and to avoid unnecessarily aggressive procedures...
  31. ncbi request reprint CD20-negative T-cell-rich B-cell lymphoma as a progression of a nodular lymphocyte-predominant Hodgkin's lymphoma treated with rituximab: a molecular analysis using laser capture microdissection
    Lara Pijuan
    Hospital del Mar IMAS IMIM, Autonomous University of Barcelona, Passeig Maritim 25 29, Barcelona 08003, Spain
    Am J Surg Pathol 29:1399-403. 2005
    ....
  32. pmc Murine embryonic stem cell-derived pancreatic acinar cells recapitulate features of early pancreatic differentiation
    Meritxell Rovira
    Cancer Research Program, Institut Municipal d Investigacio Medica, Barcelona, Spain
    Gastroenterology 135:1301-1310, 1310.e1-5. 2008
    ..However, there are limited models to study normal acinar cell differentiation in vitro. The aim of this work was to generate and characterize purified populations of pancreatic acinar cells from embryonic stem (ES) cells...
  33. doi request reprint Genomic imbalances in urothelial cancer: intratumor heterogeneity versus multifocality
    Esther Prat
    Institut de Biotecnologia i Biomedicina, Department de Biologia Cellular, Universitat Autonoma de Barcelona, Bellaterra 08193, Barcelona, Spain
    Diagn Mol Pathol 17:134-40. 2008
    ....
  34. ncbi request reprint In vitro differentiation of HT-29 M6 mucus-secreting colon cancer cells involves a trychostatin A and p27(KIP1)-inducible transcriptional program of gene expression
    Clara Mayo
    Unitat de Biologia Celñlular i Molecular, Institut Municipal d Investigacio Medica, Barcelona, Spain
    J Cell Physiol 212:42-50. 2007
    ..Therefore, the HT-29 M6 model allows the identification of some basic mechanisms of cancer cell differentiation control, so far revealing HDAC and p27(KIP1) as key regulatory factors of differentiation gene expression...
  35. ncbi request reprint Prospective study of FGFR3 mutations as a prognostic factor in nonmuscle invasive urothelial bladder carcinomas
    Silvia Hernandez
    Universitat Pompeu Fabra, Institut Municipal d Investigacio Medica, Hospital del Mar, Barcelona, Spain
    J Clin Oncol 24:3664-71. 2006
    ..To determine the frequency and the prognostic value of fibroblast growth factor receptor 3 (FGFR3) mutations in patients with nonmuscle invasive bladder tumors according to tumor stage and grade...
  36. ncbi request reprint Insertion (8;11) in a renal oncocytoma with multifocal transformation to chromophobe renal cell carcinoma
    Marta Salido
    Laboratori de Citogenètica i Biologia Molecular, Servei de Patologia, Hospital del Mar, IMAS, Universitat Autonoma de Barcelona, Passeig Maritim 25 29, Barcelona 08003, Spain
    Cancer Genet Cytogenet 163:160-3. 2005
    ..FISH techniques on paraffin tissue sections may help to identify genetic aberrations such as CCND1 rearrangement in order to establish a diagnosis of oncocytoma...
  37. ncbi request reprint Prediction of recurrence and nucleolar features in node-negative breast carcinoma, ductal type, grade II. An ultrastructural study
    Josep Lloreta
    Department of Pathology, Hospital del Mar IMAS IMIM, Universitat Pompeu Fabra, Passeig Maritim 25 29, 08003 Barcelona, Spain
    Virchows Arch 440:280-4. 2002
    ..Although electron microscopy is a highly accurate method, improving the precision of light microscopic techniques would allow more universal assessment of these nucleolar features...
  38. ncbi request reprint Vulvar angiomyxoma, aggressive angiomyxoma, and angiomyofibroblastoma: an immunohistochemical and ultrastructural study
    Francesc Alameda
    Department of Pathology, Hospital Universitari del Mar Universitat Autònoma de Barcelona, Barcelona, Catalunya, Spain
    Ultrastruct Pathol 30:193-205. 2006
    ....