A Hofman

Summary

Country: Spain

Publications

  1. ncbi [Parkinson's disease and smoking: coherence and plausibility]
    M F Allam
    Departamento de Medicina Preventiva y Salud Publica, Universidad de Cordoba, Facultad de Medicina, Cordoba, Espana
    Rev Neurol 34:686-9. 2002
  2. ncbi Smoking and Parkinson's disease: explanatory hypothesis
    Mohamed Farouk Allam
    Department of Preventive Medicine and Public Health, Faculty of Medicine, University of Cordoba, Avda Menendez Pidal, s n 14004 Cordoba, Spain
    Int J Neurosci 112:851-4. 2002
  3. ncbi [Parkinson s disease risk factors]
    M F Allam
    Departamento de Medicina Preventiva y Salud Publica, Facultad de Medicina, Universidad de Cordoba, Cordoba, Espana
    Rev Neurol 36:749-55. 2003
  4. ncbi Invasive pulmonary aspergillosis: identification of risk factors
    Mohamed Farouk Allam
    Department of Preventive Medicine and Public Health, Faculty of Medicine, University of Cordoba, Cordoba, Spain
    Scand J Infect Dis 34:819-22. 2002
  5. ncbi Incidence of parkinsonism and Parkinson disease in a general population: the Rotterdam Study
    L M L de Lau
    Department of Epidemiology and Biostatistics, Erasmus Medical Center, Rotterdam, The Netherlands
    Neurology 63:1240-4. 2004
  6. pmc Ankle brachial index combined with Framingham Risk Score to predict cardiovascular events and mortality: a meta-analysis
    F G R Fowkes
    JAMA 300:197-208. 2008
  7. ncbi Risk factors for Alzheimer's disease in Russia: a case-control study
    A V Suhanov
    Institute of Internal Medicine Siberian Branch of the Russian Academy of Medical Sciences, Novosibirsk, Russia
    Eur J Neurol 13:990-5. 2006
  8. ncbi Diet and risk of dementia: Does fat matter?: The Rotterdam Study
    M J Engelhart
    Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands
    Neurology 59:1915-21. 2002
  9. pmc Polypharmacy and falls in the middle age and elderly population
    G Ziere
    Section of Geriatric Medicine, Department of Internal Medicine, Erasmus MC, The Netherlands
    Br J Clin Pharmacol 61:218-23. 2006
  10. ncbi Angiotensin converting enzyme gene, smoking and mortality in a population-based study
    A Arias-Vasquez
    Genetic Epidemiology Unit, Department of Epidemiology and Biostatistics, Erasmus MC Rotterdam, Netherlands
    Eur J Clin Invest 35:444-9. 2005

Collaborators

Detail Information

Publications51

  1. ncbi [Parkinson's disease and smoking: coherence and plausibility]
    M F Allam
    Departamento de Medicina Preventiva y Salud Publica, Universidad de Cordoba, Facultad de Medicina, Cordoba, Espana
    Rev Neurol 34:686-9. 2002
    ..However, in other investigations this was not observed. The various studies involved showed wide variation with regard to methodology, criteria for diagnosis and periods of observation and hence it is difficult to compare them...
  2. ncbi Smoking and Parkinson's disease: explanatory hypothesis
    Mohamed Farouk Allam
    Department of Preventive Medicine and Public Health, Faculty of Medicine, University of Cordoba, Avda Menendez Pidal, s n 14004 Cordoba, Spain
    Int J Neurosci 112:851-4. 2002
    ..This systematic review raises concerns about generalization of the conclusion previously settled by many cohort and case-control studies...
  3. ncbi [Parkinson s disease risk factors]
    M F Allam
    Departamento de Medicina Preventiva y Salud Publica, Facultad de Medicina, Universidad de Cordoba, Cordoba, Espana
    Rev Neurol 36:749-55. 2003
    ..In this review we present and discuss the main risk factors (RF) for Parkinson s disease (PD) reported by epidemiological and biochemical research...
  4. ncbi Invasive pulmonary aspergillosis: identification of risk factors
    Mohamed Farouk Allam
    Department of Preventive Medicine and Public Health, Faculty of Medicine, University of Cordoba, Cordoba, Spain
    Scand J Infect Dis 34:819-22. 2002
    ..However, invasive pulmonary aspergillosis can also occur in mild granulocytopenic or even immunocompetent patients...
  5. ncbi Incidence of parkinsonism and Parkinson disease in a general population: the Rotterdam Study
    L M L de Lau
    Department of Epidemiology and Biostatistics, Erasmus Medical Center, Rotterdam, The Netherlands
    Neurology 63:1240-4. 2004
    ..To investigate the incidence of parkinsonism and Parkinson disease (PD) in the general population using in-person screening along with clinical data...
  6. pmc Ankle brachial index combined with Framingham Risk Score to predict cardiovascular events and mortality: a meta-analysis
    F G R Fowkes
    JAMA 300:197-208. 2008
    ..Prediction models to identify healthy individuals at high risk of cardiovascular disease have limited accuracy. A low ankle brachial index (ABI) is an indicator of atherosclerosis and has the potential to improve prediction...
  7. ncbi Risk factors for Alzheimer's disease in Russia: a case-control study
    A V Suhanov
    Institute of Internal Medicine Siberian Branch of the Russian Academy of Medical Sciences, Novosibirsk, Russia
    Eur J Neurol 13:990-5. 2006
    ..These findings have implications for developing preventive strategies of AD...
  8. ncbi Diet and risk of dementia: Does fat matter?: The Rotterdam Study
    M J Engelhart
    Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands
    Neurology 59:1915-21. 2002
    ....
  9. pmc Polypharmacy and falls in the middle age and elderly population
    G Ziere
    Section of Geriatric Medicine, Department of Internal Medicine, Erasmus MC, The Netherlands
    Br J Clin Pharmacol 61:218-23. 2006
    ..Falls in the elderly are common and often serious. We studied the association between multiple drug use (polypharmacy) and falls in the elderly...
  10. ncbi Angiotensin converting enzyme gene, smoking and mortality in a population-based study
    A Arias-Vasquez
    Genetic Epidemiology Unit, Department of Epidemiology and Biostatistics, Erasmus MC Rotterdam, Netherlands
    Eur J Clin Invest 35:444-9. 2005
    ..We aimed to evaluate if the ACE I/D polymorphism is related to total mortality in the elderly...
  11. ncbi Dietary fatty acids and the risk of Parkinson disease: the Rotterdam study
    L M L de Lau
    Department of Epidemiology and Biostatistics, Erasmus Medical Center, Rotterdam, The Netherlands
    Neurology 64:2040-5. 2005
    ..Unsaturated fatty acids are important constituents of neuronal cell membranes and have neuroprotective, antioxidant, and anti-inflammatory properties...
  12. ncbi Evidence for a role of the genomic region of the gene encoding for the alpha1 chain of type IX collagen (COL9A1) in hip osteoarthritis: A population-based study
    B Z Alizadeh
    Erasmus Medical Center, Rotterdam, The Netherlands
    Arthritis Rheum 52:1437-42. 2005
    ..We studied 2 COL9A1 markers (509-8B2 and 509-12B1) in relation to radiographic OA, within the framework of the Rotterdam Study, a population-based study of 7,983 subjects ages 55 years and older...
  13. pmc Angiotensin converting enzyme gene polymorphism and cardiovascular morbidity and mortality: the Rotterdam Study
    F A Sayed-Tabatabaei
    Department of Epidemiology and Biostatistics, Erasmus Medical Center, Postbus 1738, 3000 DR Rotterdam, The Netherlands
    J Med Genet 42:26-30. 2005
    ....
  14. ncbi A polymorphic CA repeat in the IGF-I gene is associated with gender-specific differences in body height, but has no effect on the secular trend in body height
    I Rietveld
    Department of Internal Medicine, Erasmus MC Rotterdam, The Netherlands
    Clin Endocrinol (Oxf) 61:195-203. 2004
    ..A polymorphism near the promoter region of the IGF-I gene has been associated with serum IGF-I levels, age-related decline of serum IGF-I levels, body height, birth weight and intima media thickness in hypertensive subjects...
  15. ncbi Retinal vessel diameters and risk of stroke: the Rotterdam Study
    M K Ikram
    Department of Epidemiology and Biostatistics, Erasmus Medical Center, Rotterdam, The Netherlands
    Neurology 66:1339-43. 2006
    ..A smaller ratio of the retinal arteriolar-to-venular diameters reportedly predicts the risk of stroke. It is unclear if this is due to arteriolar narrowing or venular dilation...
  16. ncbi A longitudinal population-based study of prothrombotic factors in elderly subjects with atrial fibrillation: the Rotterdam Study 1990-1999
    J Heeringa
    Department of Epidemiology and Biostatistics, Erasmus MC, Rotterdam, The Netherlands
    J Thromb Haemost 4:1944-9. 2006
    ..A prothrombotic or hypercoagulable state in atrial fibrillation may contribute to stroke and thromboembolism. Results of longitudinal population-based studies in elderly people with atrial fibrillation are not yet available...
  17. doi Tracking and determinants of subcutaneous fat mass in early childhood: the Generation R Study
    L Ay
    The Generation R Study Group, Erasmus Medical Center, Rotterdam, The Netherlands
    Int J Obes (Lond) 32:1050-9. 2008
    ..To examine the development and tracking of subcutaneous fat mass in the first 2 years of life and to examine which parental, fetal and postnatal characteristics are associated with subcutaneous fat mass...
  18. doi Cerebrovascular risk factors and incident depression in community-dwelling elderly
    H J Luijendijk
    Department of Epidemiology and Biostatistics, Erasmus Medical Center, Rotterdam, The Netherlands
    Acta Psychiatr Scand 118:139-48. 2008
    ..We studied the longitudinal association between cerebrovascular risk factors and incident depression in a large population-based study...
  19. doi Maternal educational level and risk of gestational hypertension: the Generation R Study
    Lm Silva
    The Generation R Study Group, Erasmus MC, University Medical Centre Rotterdam, Rotterdam, The Netherlands
    J Hum Hypertens 22:483-92. 2008
    ..The higher risk of gestational hypertension in these women is probably caused by pre-existing hypertensive tendencies that manifested themselves during pregnancy...
  20. doi Smoke exposure, airway symptoms and exhaled nitric oxide in infants: the Generation R study
    C Gabriele
    Dept of Paediatric Respiratory Medicine, Erasmus University Medical Center, Sophia Children s Hospital, The Netherlands
    Eur Respir J 32:307-13. 2008
    ..The occurrence and the severity of respiratory symptoms in the first 2 months of life are associated with lower exhaled nitric oxide fraction...
  21. doi Actigraphic sleep duration and fragmentation are related to obesity in the elderly: the Rotterdam Study
    J F van den Berg
    Department of Epidemiology and Biostatistics, Erasmus Medical Center, Rotterdam, The Netherlands
    Int J Obes (Lond) 32:1083-90. 2008
    ..Furthermore, the role of sleep fragmentation in this relationship is unknown. Our aim was to investigate the association of sleep measures with body mass index (BMI) and obesity in a normal elderly population...
  22. doi Depressive symptoms and risk of stroke: the Rotterdam Study
    M J Bos
    Department of Epidemiology and Biostatistics, Erasmus Medical Centre, 3000 CA Rotterdam, The Netherlands
    J Neurol Neurosurg Psychiatry 79:997-1001. 2008
    ..This study examines the association between depressive symptoms, depressive disorder and the risk of stroke in the general population...
  23. ncbi Relation between smoking and risk of dementia and Alzheimer disease: the Rotterdam Study
    C Reitz
    Department of Epidemiology and Biostatistics, Erasmus Medical Center, Rotterdam, The Netherlands
    Neurology 69:998-1005. 2007
    ....
  24. pmc The H63D variant in the HFE gene predisposes to arthralgia, chondrocalcinosis and osteoarthritis
    B Z Alizadeh
    Department of Epidemiology and Biostatistics, Erasmus Medical Centre, Rotterdam, The Netherlands
    Ann Rheum Dis 66:1436-42. 2007
    ..To investigate the relation between the HFE C282Y and H63D variants with arthralgia and joint pathology in the population-based Rotterdam Study...
  25. ncbi Dietary folate, vitamin B12, and vitamin B6 and the risk of Parkinson disease
    L M L de Lau
    Department of Epidemiology and Biostatistics, Erasmus Medical Center, Rotterdam, The Netherlands
    Neurology 67:315-8. 2006
    ..Moreover, vitamin B6 might influence the risk of PD through antioxidant effects unrelated to homocysteine metabolism and through its role in dopamine synthesis...
  26. ncbi Differential roles of Angiotensinogen and Angiotensin Receptor type 1 polymorphisms in breast cancer risk
    A M González-Zuloeta Ladd
    Department of Epidemiology and Biostatistics, Erasmus University Medical Center, Postbus 1738, 3000 DR, Rotterdam, The Netherlands
    Breast Cancer Res Treat 101:299-304. 2007
    ..Our results suggest that AGT plays a role in breast cancer risk in postmenopausal women, whereas the role of AGTR1 needs further studying...
  27. ncbi Variations in estrogen receptor alpha gene and risk of dementia, and brain volumes on MRI
    T den Heijer
    Department of Epidemiology and Biostatistics, Erasmus Medical Center, 3000 DR Rotterdam, The Netherlands
    Mol Psychiatry 9:1129-35. 2004
    ..50 (SE 0.10) in PP genotype, 4.45 (SE 0.06) in Pp genotype, and 4.18 ml (SE 0.08) in pp genotype (P trend=0.008). Further studies are required to investigate whether this smaller amygdalar volume has functional significance...
  28. pmc Arterial oxygen saturation, COPD, and cerebral small vessel disease
    E J van Dijk
    Department of Epidemiology and Biostatistics, Erasmus Medical Centre, The Netherlands
    J Neurol Neurosurg Psychiatry 75:733-6. 2004
    ..To study whether lower arterial oxygen saturation (SaO(2)) and chronic obstructive pulmonary disease (COPD) are associated with cerebral white matter lesions and lacunar infarcts...
  29. ncbi Markers of inflammation and cellular adhesion molecules in relation to insulin resistance in nondiabetic elderly: the Rotterdam study
    A E Hak
    Department of Epidemiology and Biostatistics, Erasmus Medical Center Rotterdam, 3000 DR Rotterdam, The Netherlands
    J Clin Endocrinol Metab 86:4398-405. 2001
    ..These factors may contribute to the well-known relationship between insulin resistance and cardiovascular disease risk and might potentially become therapeutic targets in insulin resistant subjects...
  30. ncbi Apolipoprotein E and carotid artery atherosclerosis: the Rotterdam study
    A J Slooter
    Department of Epidemiology, Erasmus Medical Center, Rotterdam, Netherlands
    Stroke 32:1947-52. 2001
    ..It is yet unclear whether the apolipoprotein E polymorphism (APOE) is related to atherosclerosis in the carotid arteries. The aim of the present study was to investigate the role of APOE in carotid artery atherosclerosis...
  31. ncbi Dietary antioxidants and peripheral arterial disease : the Rotterdam Study
    K Klipstein-Grobusch
    Department of Epidemiology and Biostatistics, Erasmus University Medical School, Rotterdam, The Netherlands
    Am J Epidemiol 154:145-9. 2001
    ..001, 0.031). Whether these differences in antioxidant intake and the risk of a low AAI and of peripheral arterial disease between sexes are attributable to a different food pattern for men compared with women remains to be elucidated...
  32. ncbi Is open-angle glaucoma associated with early menopause? The Rotterdam Study
    C A Hulsman
    The Netherlands Ophthalmic Research Institute, Amsterdam, The Netherlands
    Am J Epidemiol 154:138-44. 2001
    ..Among women who went through menopause between the ages of 45 and 49 years, the odds ratio was 1.1 (95% confidence interval: 0.7, 2.0). These findings suggest that early menopause is associated with a higher risk of open-angle glaucoma...
  33. ncbi Is carotid intima-media thickness useful in cardiovascular disease risk assessment? The Rotterdam Study
    A I del Sol
    Department of Epidemiology and Biostatistics, Erasmus Medical Center, Rotterdam, The Netherlands
    Stroke 32:1532-8. 2001
    ..We determined the contribution of common carotid intima-media thickness (IMT) in the prediction of future coronary heart disease and cerebrovascular disease when added to established risk factors...
  34. ncbi Serum carotenoids and cerebral white matter lesions: the Rotterdam scan study
    T den Heijer
    Department of Epidemiology and Biostatistics, Erasmus Medical Center, Rotterdam, The Netherlands
    J Am Geriatr Soc 49:642-6. 2001
    ..Longitudinal studies with repeated measurements of both carotenoids and WMLs are necessary to explore this hypothesis further...
  35. ncbi Antihypertensive drugs and incidence of dementia: the Rotterdam Study
    A Ruitenberg
    Department of Epidemiology and Biostatistics, Erasmus Medical Center, Rotterdam, The Netherlands
    Neurobiol Aging 22:407-12. 2001
    ..87, not significant. Dementia may be prevented by antihypertensive treatment. In order to confirm any relation in Alzheimer's disease larger observational studies with longer follow-up are needed...
  36. ncbi Risk factors for age-related macular degeneration: Pooled findings from three continents
    W Smith
    National Centre for Epidemiology and Population Health, Australian National University, Canberra, Australia
    Ophthalmology 108:697-704. 2001
    ..CONCLUSIONS: These combined data from racially similar communities across three continents provide strong and consistent evidence that tobacco smoking is the principal known preventable exposure associated with any form of AMD...
  37. ncbi CYP2D6 polymorphism in Parkinson's disease: the Rotterdam Study
    B S Harhangi
    Department of Epidemiology and Biostatistics, Erasmus Medical Center Rotterdam, The Netherlands
    Mov Disord 16:290-3. 2001
    ..Our result supports the hypothesis that the CYP2D6 gene is not a major gene responsible for PD...
  38. ncbi Parity and carotid artery atherosclerosis in elderly women: The Rotterdam Study
    K H Humphries
    Centre for Health Evaluation and Outcome Sciences, St Paul's Hospital, Vancouver, Canada
    Stroke 32:2259-64. 2001
    ....
  39. ncbi Variable expression of presenilin 1 is not a major determinant of risk for late-onset Alzheimer's disease
    B Dermaut
    University of Antwerp, Department of Biochemistry Universiteitsplein 1, Antwerpen, Belgium
    J Neurol 248:935-9. 2001
    ..In the meta-analysis no major differences between patients and controls were found for the PSEN1 intronic variation. Together, our results do not support a major role for variable expression of PSEN1 in LOAD...
  40. ncbi Hypertension and cerebral white matter lesions in a prospective cohort study
    F E de Leeuw
    Department of Epidemiology and Biostatistics, Erasmus University Medical Centre, Rotterdam, The Netherlands
    Brain 125:765-72. 2002
    ..Adequate treatment of hypertension may therefore prevent white matter lesions and the associated cognitive decline...
  41. ncbi Effect of smoking on global cognitive function in nondemented elderly
    A Ott
    Department of Epidemiology and Biostatistics Drs Hofman, Launer, Ott, and Stijnen, Erasmus University Medical Centre, The Netherlands
    Neurology 62:920-4. 2004
    ..Contrary to early case-control studies that suggested smoking protects against Alzheimer disease (AD), recent prospective studies have shown that elderly who smoke may be at increased risk for dementia...
  42. pmc A study of gene--environment interaction on the gene for angiotensin converting enzyme: a combined functional and population based approach
    F A Sayed-Tabatabaei
    Department of Epidemiology and Biostatistics, Erasmus Medical Center, Rotterdam, The Netherlands
    J Med Genet 41:99-103. 2004
    ..In this paper, we used a combined functional and population based approach to investigate the gene-environment interaction of the ACE I/D polymorphism in relation to carotid artery wall thickness...
  43. ncbi Dietary antioxidants and the risk of ischemic stroke: the Rotterdam Study
    Z Voko
    Department of Epidemiology and Biostatistics, Erasmus Medical Center Rotterdam, The Netherlands
    Neurology 61:1273-5. 2003
    ..These results agree with the view that high dietary intake of antioxidants, in particular vitamin C and--in smokers--vitamin E, reduces the risk of stroke...
  44. ncbi A clinical-genetic study of Parkinson's disease in a genetically isolated community
    M C J Dekker
    Genetic Epidemiologic Unit, Dept of Epidemiology, Erasmus MC, Rotterdam, The Netherlands
    J Neurol 250:1056-62. 2003
    ..The finding of a common ancestor in 41 idiopathic-PD patients along with the exclusion of known PD genes and loci suggests the presence of at least one other, yet unknown, susceptibility gene involved in PD in this population...
  45. ncbi Pharmacologic agents associated with a preventive effect on Alzheimer's disease: a review of the epidemiologic evidence
    B A in 't Veld
    Department of Epidemiology and Biostatistics, Erasmus Medical Center Rotterdam, P O Box 1738, 3000 DR Rotterdam, The Netherlands
    Epidemiol Rev 24:248-68. 2002
  46. ncbi Genetic epidemiology of amyotrophic lateral sclerosis
    D Majoor-Krakauer
    Department of Clinical Genetics, Erasmus Medical Center, Rotterdam, The Netherlands
    Clin Genet 63:83-101. 2003
    ....
  47. ncbi Coronary calcification detected by electron-beam computed tomography and myocardial infarction. The Rotterdam Coronary Calcification Study
    R Vliegenthart
    Department of Epidemiology and Biostatistics, Erasmus Medical Center, Rotterdam, The Netherlands
    Eur Heart J 23:1596-1603. 2002
    ..We cross-sectionally examined the association between coronary calcification and myocardial infarction in the prospective Rotterdam Coronary Calcification Study...
  48. pmc Cerebral haemodynamics and depression in the elderly
    H Tiemeier
    Department of Epidemiology and Biostatistics, Erasmus Medical Centre Rotterdam, Rotterdam, Netherlands
    J Neurol Neurosurg Psychiatry 73:34-9. 2002
    ....
  49. ncbi Bone mineral density and the risk of peripheral arterial disease: the Rotterdam Study
    M van der Klift
    Institute of Medical Technology Assessment, Erasmus Medical Center, Rotterdam, The Netherlands
    Calcif Tissue Int 70:443-9. 2002
    ..Estrogen deficiency may be the common denominator in osteoporosis and PAD, resulting in clustering of these two major diseases in postmenopausal women...
  50. ncbi Anthropometric measures, fitness and habitual physical activity in offspring of hypertensive parents. Dutch Hypertension and Offspring Study
    D C de Visser
    Department of Epidemiology and Biostatistics, Erasmus University Medical School, Rotterdam, The Netherlands
    Am J Hypertens 7:242-8. 1994
    ..Fitness or habitual physical activity are, however, not different between groups of subjects at different risk for future hypertension...